VOLUME 5 (2014)
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About The Cover
Wild-type p110α has more interactions with the nSH2 domain than the oncogenic mutant H1047R. See Gabelli et. al.
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Table of Contents
Editorial
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| Immunogenic cell death inducers as anticancer agents |
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https://doi.org/10.18632/oncotarget.2266
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| 5190-5191 |
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| Targeting lemurs against cancer metastasis |
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https://doi.org/10.18632/oncotarget.2271
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| 5192-5193 |
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| Ras in epidermal proliferation |
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https://doi.org/10.18632/oncotarget.2275
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| 5194-5195 |
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| Knowledgebased computational models |
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https://doi.org/10.18632/oncotarget.2276
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| 5196-5197 |
Priority Research Papers
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| Structural basis of nSH2 regulation and lipid binding in PI3Kα |
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https://doi.org/10.18632/oncotarget.2263
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| 5198-5208 |
Clinical Research Papers
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| NYESO1 as a potential immunotherapeutic target in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.2101
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| 5209-5217 |
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| An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma LGPUCC and its potential use for surveillance after transurethral resection using urine |
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https://doi.org/10.18632/oncotarget.2129
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| 5218-5233 |
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| Low PKCα expression within the MRDHR stratum defines a new subgroup of childhood TALL with very poor outcome |
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https://doi.org/10.18632/oncotarget.2062
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| 5234-5245 |
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| High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients |
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https://doi.org/10.18632/oncotarget.2124
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| 5246-5256 |
Research Papers
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| LASP1 is a novel BCRABL substrate and a phosphorylationdependent binding partner of CRKL in chronic myeloid leukemia |
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https://doi.org/10.18632/oncotarget.2072
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| 5257-5271 |
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| CD271 is an imperfect marker for melanoma initiating cells |
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https://doi.org/10.18632/oncotarget.1967
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| 5272-5283 |
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| Circulating miR148b and miR133a as biomarkers for breast cancer detection |
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https://doi.org/10.18632/oncotarget.2014
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| 5284-5294 |
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| Loss of ARID1A expression sensitizes cancer cells to PI3K and AKTinhibition |
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https://doi.org/10.18632/oncotarget.2092
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| 5295-5303 |
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| A FcγRIIIengaging bispecific antibody expands the range of HER2expressing breast tumors eligible to antibody therapy |
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https://doi.org/10.18632/oncotarget.2093
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| 5304-5319 |
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| Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration |
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https://doi.org/10.18632/oncotarget.2097
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| 5320-5334 |
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| Galectin4 expression is associated with reduced lymph node metastasis and modulation of Wnt/βcatenin signalling in pancreatic adenocarcinoma |
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https://doi.org/10.18632/oncotarget.2104
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| 5335-5349 |
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| Macrophages are recruited to hypoxic tumor areas and acquire a ProAngiogenic M2Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin |
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https://doi.org/10.18632/oncotarget.2110
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| 5350-5368 |
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| GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the βcatenin signaling |
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https://doi.org/10.18632/oncotarget.2105
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| 5369-5380 |
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| Combined therapy with RAD001 e BEZ235 overcomes resistance of PET immortalized cell lines to mTOR inhibition |
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https://doi.org/10.18632/oncotarget.2111
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| 5381-5391 |
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| FOXO1 downregulation contributes to the oncogenic program of primary mediastinal Bcell lymphoma |
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https://doi.org/10.18632/oncotarget.2107
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| 5392-5402 |
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| Tumor suppressor XAF1 induces apoptosis inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.2114
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| 5403-5415 |
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| MiR143 acts as a tumor suppressor by targeting NRAS and enhances temozolomideinduced apoptosis in glioma |
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https://doi.org/10.18632/oncotarget.2116
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| 5416-5427 |
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| The response of head and neck squamous cell carcinoma to cetuximab treatment depends on Aurora kinase A polymorphism |
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https://doi.org/10.18632/oncotarget.2117
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| 5428-5438 |
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| Tumorderived exosomes promote tumor progression and Tcell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.2118
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| 5439-5452 |
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| Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth |
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https://doi.org/10.18632/oncotarget.2113
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| 5453-5471 |
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| Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes |
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https://doi.org/10.18632/oncotarget.2121
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| 5472-5482 |
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| Hedgehog signaling sensitizes Glioma stem cells to endogenous nanoirradiation |
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https://doi.org/10.18632/oncotarget.2123
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| 5483-5493 |
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| A nucleolinDNMT1 regulatory axis in acute myeloid leukemogenesis |
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https://doi.org/10.18632/oncotarget.2131
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| 5494-5509 |
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| Sustained conditional knockdown reveals intracellular bone sialoprotein as essential for breast cancer skeletal metastasis |
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https://doi.org/10.18632/oncotarget.2132
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| 5510-5522 |
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| Sensitization of radioresistant prostate cancer cells with a unique cytolethal distending toxin |
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https://doi.org/10.18632/oncotarget.2133
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| 5523-5534 |
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| Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD |
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https://doi.org/10.18632/oncotarget.2137
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| 5535-5546 |
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| Hepatocyte growth factorlike protein is required for prostate tumor growth in the TRAMP mouse model |
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https://doi.org/10.18632/oncotarget.2139
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| 5547-5558 |
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| Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway |
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https://doi.org/10.18632/oncotarget.2140
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| 5559-5569 |
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| Small interfering RNA siRNAmediated knockdown of macrophage migration inhibitory factor MIF suppressed cyclin D1 expression and hepatocellular carcinoma cell proliferation |
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https://doi.org/10.18632/oncotarget.2141
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| 5570-5580 |
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| Specific delivery of microRNA93 into HBVreplicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA |
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https://doi.org/10.18632/oncotarget.2143
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| 5581-5590 |
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| E3ligase Skp2 predicts poor prognosis and maintains cancer stem cell pool in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.2149
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| 5591-5601 |
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| The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.2136
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| 5602-5614 |
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| Development of replicationcompetent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter |
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https://doi.org/10.18632/oncotarget.2151
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| 5615-5623 |
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| Upregulation of microRNA135a3p and death receptor 5 plays a critical role in Tanshinone I sensitized prostate cancer cells to TRAIL induced apoptosis |
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https://doi.org/10.18632/oncotarget.2152
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| 5624-5636 |
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| Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells |
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https://doi.org/10.18632/oncotarget.2154
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| 5637-5650 |
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| A novel class I HDAC inhibitor MPT0G030 induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and Ecadherin |
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https://doi.org/10.18632/oncotarget.2155
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| 5651-5662 |
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| TFF1 activates p53 through downregulation of miR504 in gastric cancer |
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https://doi.org/10.18632/oncotarget.2156
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| 5663-5673 |
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| Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX970 |
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https://doi.org/10.18632/oncotarget.2158
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| 5674-5685 |
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| Multiple myeloma cellderived microvesicles are enriched in CD147 expression and enhance tumor cell proliferation |
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https://doi.org/10.18632/oncotarget.2159
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| 5686-5699 |
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| Loss of PPM1A expression enhances invasion and the epithelialtomesenchymal transition in bladder cancer by activating the TGFβ/Smad signaling pathway |
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https://doi.org/10.18632/oncotarget.2144
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| 5700-5711 |
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| FAS/FASL are dysregulated in chordoma and their lossoffunction impairs zebrafish notochord formation |
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https://doi.org/10.18632/oncotarget.2145
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| 5712-5724 |
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| Regulatory role of miR1423p on the functional hepatic cancer stem cell marker CD133 |
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https://doi.org/10.18632/oncotarget.2167
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| 5725-5735 |
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| HPrune through GSK3β interaction sustains canonical WNT/βcatenin signaling enhancing cancer progression in NSCLC |
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https://doi.org/10.18632/oncotarget.2169
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| 5736-5749 |
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| The ALK inhibitor ASP3026 eradicates NPMALK+ Tcell anaplastic largecell lymphoma in vitro and in a systemic xenograft lymphoma model |
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https://doi.org/10.18632/oncotarget.2170
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| 5750-5763 |
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| Dissecting DNA repair in adult high grade gliomas for patient stratification in the postgenomic era |
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https://doi.org/10.18632/oncotarget.2180
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| 5764-5781 |
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| Thrombospondin 1 promotes an aggressive phenotype through epithelialtomesenchymal transition in human melanoma |
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https://doi.org/10.18632/oncotarget.2164
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| 5782-5797 |
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| Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells |
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https://doi.org/10.18632/oncotarget.2185
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| 5798-5807 |
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| Oncogenemediated regulation of p53 ISGylation and functions |
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https://doi.org/10.18632/oncotarget.2199
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| 5808-5818 |
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| Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patientderived xenografts |
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https://doi.org/10.18632/oncotarget.2171
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| 5819-5831 |
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| HERG1 functions as an oncogene in pancreatic cancer and is downregulated by miR96 |
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https://doi.org/10.18632/oncotarget.2200
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| 5832-5844 |
Research Perspectives
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| Caspase2 regulates oncogeneinduced senescence |
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https://doi.org/10.18632/oncotarget.2286
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| 5845-5847 |
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