VOLUME 5 (2014)
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Structural modeling of celecoxib, DMC and other small molecule inhibitors binding to CDH11 and inhibiting the growth of MDA-MB-231 cells. Sd-133 binding capability to CDH11 was validated by SPR. Shown is a EC1 homodimer interface of CDH11 (PDB: 2A4C); one monomer is represented by the Van der Waals molecular surface (green) and the other by a ribbon. See Assefnia et al.
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Table of Contents
Editorial
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| Invasive leader cells: metastatic oncotarget |
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https://doi.org/10.18632/oncotarget.1870
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| 1390-1391 |
Reviews
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| Molecular pathways and therapeutic targets in lung cancer |
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https://doi.org/10.18632/oncotarget.1891
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| 1392-1433 |
Research Perspectives
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| The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer |
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https://doi.org/10.18632/oncotarget.1846
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| 1434-1438 |
Research Papers
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| Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer |
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https://doi.org/10.18632/oncotarget.1444
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| 1439-1451 |
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| The genetic landscape of anaplastic astrocytoma |
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https://doi.org/10.18632/oncotarget.1505
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| 1452-1457 |
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| Cadherin11 in poor prognosis malignancies and rheumatoid arthritis: common target common therapies |
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https://doi.org/10.18632/oncotarget.1538
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| 1458-1474 |
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| Celecoxib suppresses hepatoma stemness and progression by upregulating PTEN |
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https://doi.org/10.18632/oncotarget.1745
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| 1475-1490 |
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| Ckit induces epithelial–mesenchymal transition and contributes to salivary adenoid cystic cancer progression |
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https://doi.org/10.18632/oncotarget.1606
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| 1491-1501 |
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| Cotargeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity |
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https://doi.org/10.18632/oncotarget.1609
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| 1502-1514 |
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| Mutations in IDH1 IDH2 and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas |
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https://doi.org/10.18632/oncotarget.1765
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| 1515-1525 |
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| Atg7 and Keap1dependent autophagy protects breast cancer cell lines against mitoquinoneinduced oxidative stress |
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https://doi.org/10.18632/oncotarget.1715
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| 1526-1537 |
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| The receptor for urokinaseplasminogen activator uPAR controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style |
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https://doi.org/10.18632/oncotarget.1754
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| 1538-1553 |
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| RhoGDI2 promotes epithelialmesenchymal transition via induction of Snail in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.1733
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| 1554-1564 |
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| Thermoregulatory correlates of nausea in rats and musk shrews |
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https://doi.org/10.18632/oncotarget.1732
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| 1565-1575 |
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| Roles of neutrophil gelatinaseassociated lipocalin NGAL in human cancer |
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https://doi.org/10.18632/oncotarget.1738
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| 1576-1594 |
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| Prostate cancerderived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment |
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https://doi.org/10.18632/oncotarget.1570
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| 1595-1608 |
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| TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancerselective target pathway with therapeutic opportunities |
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https://doi.org/10.18632/oncotarget.1707
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| 1609-1620 |
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| Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43mediated gap junctional intercellular communication |
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https://doi.org/10.18632/oncotarget.1764
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| 1621-1634 |
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| Diagnosis of bladder cancer and prediction of survival by urinary metabolomics |
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https://doi.org/10.18632/oncotarget.1744
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| 1635-1645 |
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| Androgen receptor splice variants activating the fulllength receptor in mediating resistance to androgendirected therapy |
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https://doi.org/10.18632/oncotarget.1802
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| 1646-1656 |
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| Linking differential radiation responses to glioma heterogeneity |
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https://doi.org/10.18632/oncotarget.1823
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| 1657-1665 |
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| The NLRrelated protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling |
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https://doi.org/10.18632/oncotarget.1850
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| 1666-1682 |
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| Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells |
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https://doi.org/10.18632/oncotarget.1849
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| 1683-1698 |
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