VOLUME 6 (2015)
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About The Cover
JNK inhibitor pretreatment sensitizes pancreatic cancer stem cells to 5-fluorouracil and gemcitabine. See Suzuki et al.
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Table of Contents
News
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| DNA replication stress as an Achilles’ heel of cancer |
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https://doi.org/10.18632/oncotarget.3147
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| 1-2 |
Editorial
Reviews
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| MicroRNAs in Bcells: from normal differentiation to treatment of malignancies |
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https://doi.org/10.18632/oncotarget.3057
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| 7-25 |
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| An update on the LIM and SH3 domain protein 1 LASP1: a versatile structural signaling and biomarker protein |
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https://doi.org/10.18632/oncotarget.3083
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| 26-42 |
Priority Research Papers
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| Syringaresinol protects against hypoxia/reoxygenationinduced cardiomyocytes injury and death by destabilization of HIF1α in a FOXO3dependent mechanism |
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https://doi.org/10.18632/oncotarget.2723
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| 43-55 |
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| Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.2695
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| 56-70 |
Research Papers
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| Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells |
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https://doi.org/10.18632/oncotarget.2698
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| 71-84 |
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| WMJS001 a novel aliphatic hydroxamate derivative exhibits antiangiogenic activities via Srchomology2domaincontaining protein tyrosine phosphatase 1 |
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https://doi.org/10.18632/oncotarget.2765
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| 85-100 |
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| Decreased expression of GRIM19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.2684
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| 101-115 |
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| RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with cMyc amplification |
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https://doi.org/10.18632/oncotarget.2699
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| 116-129 |
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| Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells |
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https://doi.org/10.18632/oncotarget.2766
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| 130-143 |
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| CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance |
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https://doi.org/10.18632/oncotarget.2670
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| 144-158 |
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| Dendritic cells respond to nasopharygeal carcinoma cells through annexin A2recognizing DCSIGN |
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https://doi.org/10.18632/oncotarget.2700
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| 159-170 |
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| Patientderived glioblastoma stem cells are killed by CD133specific CAR T cells but induce the T cell aging marker CD57 |
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https://doi.org/10.18632/oncotarget.2767
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| 171-184 |
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| A novel PI3K inhibitor PIKC98 displays potent preclinical activity against multiple myeloma |
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https://doi.org/10.18632/oncotarget.2688
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| 185-195 |
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| Targeting ornithine decarboxylase reverses the LIN28/Let7 axis and inhibits glycolytic metabolism in neuroblastoma |
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https://doi.org/10.18632/oncotarget.2768
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| 196-206 |
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| EpsteinBarr virus latent membrane protein 2A suppresses the expression of HER2 via a pathway involving TWIST and YB1 in EpsteinBarr virusassociated gastric carcinomas |
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https://doi.org/10.18632/oncotarget.2702
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| 207-220 |
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| Truncated RAF kinases drive resistance to MET inhibition in METaddicted cancer cells |
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https://doi.org/10.18632/oncotarget.2771
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| 221-233 |
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| PDL1 is highly expressed in Enzalutamide resistant prostate cancer |
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https://doi.org/10.18632/oncotarget.2703
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| 234-242 |
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| CD147 promotes Srcdependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.2801
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| 243-257 |
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| Resistin promotes tumor metastasis by downregulation of miR519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells |
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https://doi.org/10.18632/oncotarget.2724
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| 258-270 |
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| GCN5 inhibits XBP1Smediated transcription by antagonizing PCAF action |
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https://doi.org/10.18632/oncotarget.2773
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| 271-287 |
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| MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand |
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https://doi.org/10.18632/oncotarget.2672
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| 288-304 |
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| Hypoxiainducible factor 1 alpha is regulated by RBM38 a RNAbinding protein and a p53 family target via mRNA translation |
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https://doi.org/10.18632/oncotarget.2786
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| 305-316 |
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| Mir243p downregulation contributes to VP16–DDP resistance in smallcell lung cancer by targeting ATG4A |
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https://doi.org/10.18632/oncotarget.2787
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| 317-331 |
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| New mechanistic insights of integrin β1 in breast cancer bone colonization |
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https://doi.org/10.18632/oncotarget.2788
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| 332-344 |
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| Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC743380 |
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https://doi.org/10.18632/oncotarget.2814
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| 345-354 |
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| PAK6 increase chemoresistance and is a prognostic marker for stage II and III colon cancer patients undergoing 5FU based chemotherapy |
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https://doi.org/10.18632/oncotarget.2803
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| 355-367 |
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| EPB41L3 TSP1 and RASSF2 as new clinically relevant prognostic biomarkers in diffuse gliomas |
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https://doi.org/10.18632/oncotarget.2745
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| 368-380 |
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| MIG7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis |
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https://doi.org/10.18632/oncotarget.2804
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| 381-393 |
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| DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in nonsmall cell lung cancers |
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https://doi.org/10.18632/oncotarget.2697
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| 394-408 |
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| Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on antiapoptotic Mcl1 |
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https://doi.org/10.18632/oncotarget.2774
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| 409-426 |
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| DNA damageinduced S and G2/M cell cycle arrest requires mTORC2dependent regulation of Chk1 |
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https://doi.org/10.18632/oncotarget.2813
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| 427-440 |
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| MicroRNA34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Rasactivated prostate cancer |
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https://doi.org/10.18632/oncotarget.2690
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| 441-457 |
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| JNK suppression of chemotherapeutic agentsinduced ROS confers chemoresistance on pancreatic cancer stem cells |
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https://doi.org/10.18632/oncotarget.2693
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| 458-470 |
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| MiR578 and miR573 as potential players in BRCArelated breast cancer angiogenesis |
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https://doi.org/10.18632/oncotarget.2509
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| 471-483 |
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| A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer |
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https://doi.org/10.18632/oncotarget.2861
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| 484-493 |
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| miR125a5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis |
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https://doi.org/10.18632/oncotarget.2674
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| 494-509 |
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| The small molecule tyrosine kinase inhibitor NVPBHG712 antagonizes ABCC10mediated paclitaxel resistance: a preclinical and pharmacokinetic study |
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https://doi.org/10.18632/oncotarget.2638
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| 510-521 |
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| Divergent behaviors and underlying mechanisms of cell migration and invasion in nonmetastatic T24 and its metastatic derivative T24T bladder cancer cell lines |
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https://doi.org/10.18632/oncotarget.2680
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| 522-536 |
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| Long noncoding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner |
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https://doi.org/10.18632/oncotarget.2681
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| 537-546 |
Clinical Research Papers
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| Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence |
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https://doi.org/10.18632/oncotarget.2772
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| 547-555 |
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| Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia |
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https://doi.org/10.18632/oncotarget.2785
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| 556-569 |
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| The landscape of metastatic progression patterns across major human cancers |
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https://doi.org/10.18632/oncotarget.2677
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| 570-583 |
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