VOLUME 6 (2015)
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Confocal immunofluorescent images showing the nuclear localization of EGFR co-localize with Cyclin D1. See Pereira et al.
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Table of Contents
Addendum
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| Identification of a chrXq273 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients |
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https://doi.org/10.18632/oncotarget.3998
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| 9643 |
Editorial
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| MicroRNA21 T helper lineage and autoimmunity |
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https://doi.org/10.18632/oncotarget.3928
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| 9644-9645 |
Reviews
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| Polypharmacology of small molecules targeting the ubiquitin–proteasome and ubiquitinlike systems |
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https://doi.org/10.18632/oncotarget.3917
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| 9646-9656 |
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| Deubiquitinating enzymes as oncotargets |
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https://doi.org/10.18632/oncotarget.3922
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| 9657-9668 |
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| Ecology meets cancer biology: the cancer swamp promotes the lethal cancer phenotype |
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https://doi.org/10.18632/oncotarget.3430
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| 9669-9678 |
Research Papers: Pathology
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| Nuclear localization of epidermal growth factor receptor EGFR in ameloblastomas |
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https://doi.org/10.18632/oncotarget.3919
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| 9679-9685 |
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| Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARαPAC mice due to dysregulated bile acid synthesis |
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https://doi.org/10.18632/oncotarget.3531
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| 9686-9700 |
Research Papers: Gerotarget (Focus on Aging)
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| EGCGmediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells |
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https://doi.org/10.18632/oncotarget.3832
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| 9701-9717 |
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| Rapatar a nanoformulation of rapamycin decreases chemicallyinduced benign prostate hyperplasia in rats |
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https://doi.org/10.18632/oncotarget.3929
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| 9718-9727 |
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| New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormonereleasing hormone receptor |
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https://doi.org/10.18632/oncotarget.3303
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| 9728-9739 |
Research Papers
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| Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach |
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https://doi.org/10.18632/oncotarget.3149
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| 9740-9755 |
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| Silencing of RSpondin1 increases radiosensitivity of glioma cells |
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https://doi.org/10.18632/oncotarget.3395
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| 9756-9765 |
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| EMMPRIN/CD147 is a novel coreceptor of VEGFR2 mediating its activation by VEGF |
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https://doi.org/10.18632/oncotarget.2870
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| 9766-9780 |
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| Flotillin2 promotes nasopharyngeal carcinoma metastasis and is necessary for the epithelialmesenchymal transition induced by transforming growth factorβ |
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https://doi.org/10.18632/oncotarget.3382
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| 9781-9793 |
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| Netrin4 as a biomarker promotes cell proliferation and invasion in gastric cancer |
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https://doi.org/10.18632/oncotarget.3400
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| 9794-9806 |
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| NGFinduced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib |
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https://doi.org/10.18632/oncotarget.3227
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| 9807-9819 |
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| Hypoxia/reoxygenationexperienced cancer cell migration and metastasis are regulated by Rap1 and Rac1GTPase activation via the expression of thymosin beta4 |
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https://doi.org/10.18632/oncotarget.3218
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| 9820-9833 |
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| Cordycepin 3’deoxyadenosine suppressed HMGA2 Twist1 and ZEB1dependent melanoma invasion and metastasis by targeting miR33b |
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https://doi.org/10.18632/oncotarget.3383
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| 9834-9853 |
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| Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation |
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https://doi.org/10.18632/oncotarget.3396
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| 9854-9876 |
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| PAK1mediated MORC2 phosphorylation promotes gastric tumorigenesis |
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https://doi.org/10.18632/oncotarget.3185
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| 9877-9886 |
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| Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas |
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https://doi.org/10.18632/oncotarget.3195
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| 9887-9896 |
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| Targeting Tolllike receptor 2 inhibits growth of head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.3393
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| 9897-9907 |
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| Interleukin21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis |
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https://doi.org/10.18632/oncotarget.3532
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| 9908-9923 |
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| HSPA12B: a novel facilitator of lung tumor growth |
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https://doi.org/10.18632/oncotarget.3533
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| 9924-9936 |
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| A suppressive role of ionizing radiationresponsive miR29c in the development of liver carcinoma via targeting WIP1 |
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https://doi.org/10.18632/oncotarget.3157
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| 9937-9950 |
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| Circadian genes Per1 and Per2 increase radiosensitivity of glioma in vivo |
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https://doi.org/10.18632/oncotarget.3179
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| 9951-9958 |
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| Valproic acid promotes radiosensitization in meningioma stemlike cells |
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https://doi.org/10.18632/oncotarget.3692
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| 9959-9969 |
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| Delphinidin sensitizes prostate cancer cells to TRAILinduced apoptosis by inducing DR5 and causing caspasemediated HDAC3 cleavage |
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https://doi.org/10.18632/oncotarget.3667
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| 9970-9984 |
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| CXCR6 expression in nonsmall cell lung carcinoma supports metastatic process via modulating metalloproteinases |
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https://doi.org/10.18632/oncotarget.3194
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| 9985-9998 |
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| Aspirin counteracts cancer stem cell features desmoplasia and gemcitabine resistance in pancreatic cancer |
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https://doi.org/10.18632/oncotarget.3171
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| 9999-10015 |
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| Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells |
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https://doi.org/10.18632/oncotarget.3540
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| 10016-10029 |
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| Manipulation of prostate cancer metastasis by locusspecific modification of the CRMP4 promoter region using chimeric TALE DNA methyltransferase and demethylase |
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https://doi.org/10.18632/oncotarget.3192
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| 10030-10044 |
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| Vasorin is a potential serum biomarker and drug target of hepatocarcinoma screened by subtractiveEMSASELEX to clinic patient serum |
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https://doi.org/10.18632/oncotarget.3541
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| 10045-10059 |
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| XPC inhibits NSCLC cell proliferation and migration by enhancing ECadherin expression |
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https://doi.org/10.18632/oncotarget.3542
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| 10060-10072 |
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| NF2 blocks Snailmediated p53 suppression in mesothelioma |
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https://doi.org/10.18632/oncotarget.3543
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| 10073-10085 |
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| MET receptor is a potential therapeutic target in high grade cervical cancer |
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https://doi.org/10.18632/oncotarget.3161
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| 10086-10101 |
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| Coactivation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver |
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https://doi.org/10.18632/oncotarget.3546
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| 10102-10115 |
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| Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways |
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https://doi.org/10.18632/oncotarget.2687
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| 10116-10133 |
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| Glucose starvationmediated inhibition of salinomycin induced autophagy amplifies cancer cell specific cell death |
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https://doi.org/10.18632/oncotarget.3548
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| 10134-10145 |
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| Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinibresistant nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.3380
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| 10146-10160 |
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| Critical role of gap junction communication calcium and nitric oxide signaling in bystander responses to focal photodynamic injury |
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https://doi.org/10.18632/oncotarget.3553
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| 10161-10174 |
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| Yesmediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells |
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https://doi.org/10.18632/oncotarget.3391
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| 10175-10194 |
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| The miR193a3pregulated ING5 gene activates the DNA damage response pathway and inhibits multichemoresistance in bladder cancer |
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https://doi.org/10.18632/oncotarget.3555
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| 10195-10206 |
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| Preclinical evaluation of the MDM2p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma |
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https://doi.org/10.18632/oncotarget.3504
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| 10207-10221 |
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| Lung tumorigenesis induced by human vascular endothelial growth factor hVEGFA165 overexpression in transgenic mice and amelioration of tumor formation by miR16 |
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https://doi.org/10.18632/oncotarget.3390
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| 10222-10238 |
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| WNT5A promotes stemness characteristics in nasopharyngeal carcinoma cells leading to metastasis and tumorigenesis |
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https://doi.org/10.18632/oncotarget.3518
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| 10239-10252 |
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| Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer |
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https://doi.org/10.18632/oncotarget.3520
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| 10253-10266 |
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| Oncogenic extracellular HSP70 disrupts the gapjunctional coupling between capillary cells |
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https://doi.org/10.18632/oncotarget.3522
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| 10267-10283 |
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| MPGES1derived PGE2 suppresses CD80 expression on tumorassociated phagocytes to inhibit antitumor immune responses in breast cancer |
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https://doi.org/10.18632/oncotarget.3581
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| 10284-10296 |
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| MicroRNA144 suppresses osteosarcoma growth and metastasis by targeting ROCK1 and ROCK2 |
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https://doi.org/10.18632/oncotarget.3305
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| 10297-10308 |
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| Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cells |
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https://doi.org/10.18632/oncotarget.3582
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| 10309-10319 |
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| HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity |
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https://doi.org/10.18632/oncotarget.3583
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| 10320-10334 |
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| Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale labelfree comparative proteomics approach |
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https://doi.org/10.18632/oncotarget.3231
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| 10335-10349 |
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| Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the βcatenin/TCF complex association via FOXO3a activation |
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https://doi.org/10.18632/oncotarget.3585
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| 10350-10365 |
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| Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 SRR2 reporter |
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https://doi.org/10.18632/oncotarget.3590
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| 10366-10373 |
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| Potentiating the cellular targeting and antitumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells |
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https://doi.org/10.18632/oncotarget.3606
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| 10374-10398 |
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| PI3K paninhibition impairs more efficiently proliferation and survival of Tcell acute lymphoblastic leukemia cell lines when compared to isoformselective PI3K inhibitors |
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https://doi.org/10.18632/oncotarget.3295
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| 10399-10414 |
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| IL8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer |
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https://doi.org/10.18632/oncotarget.3389
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| 10415-10431 |
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| Dysregulation of the miR34aSIRT1 axis inhibits breast cancer stemness |
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https://doi.org/10.18632/oncotarget.3394
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| 10432-10444 |
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| Novel agents that downregulate EGFR HER2 and HER3 in parallel |
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https://doi.org/10.18632/oncotarget.3398
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| 10445-10459 |
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| Icaritin suppresses multiple myeloma by inhibiting IL6/JAK2/STAT3 |
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https://doi.org/10.18632/oncotarget.3399
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| 10460-10472 |
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| Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion |
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https://doi.org/10.18632/oncotarget.3401
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| 10473-10486 |
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| Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers |
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https://doi.org/10.18632/oncotarget.3402
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| 10487-10497 |
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| Loss of Cbl and Cblb ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy |
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https://doi.org/10.18632/oncotarget.3403
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| 10498-10509 |
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| HDACi inhibits liposarcoma via targeting of the MDM2p53 signaling axis and PTEN irrespective of p53 mutational status |
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https://doi.org/10.18632/oncotarget.3230
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| 10510-10520 |
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| Integrated genomic analysis identifies subclasses and prognosis signatures of kidney cancer |
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https://doi.org/10.18632/oncotarget.3294
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| 10521-10531 |
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| Multiple myeloma induces Mcl1 expression and survival of myeloidderived suppressor cells |
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https://doi.org/10.18632/oncotarget.3300
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| 10532-10547 |
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| Loss of INPP4B causes a DNA repair defect through loss of BRCA1 ATM and ATR and can be targeted with PARP inhibitor treatment |
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https://doi.org/10.18632/oncotarget.3307
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| 10548-10562 |
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| Powerful antitumor and antiangiogenic activity of a new antivascular endothelial growth factor receptor 1 peptide in colorectal cancer models |
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https://doi.org/10.18632/oncotarget.3384
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| 10563-10576 |
Clinical Research Papers
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| ROS1 rearrangements in lung adenocarcinoma: prognostic impact therapeutic options and genetic variability |
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https://doi.org/10.18632/oncotarget.3387
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| 10577-10585 |
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| Deregulation of dicer and mir155 expression in liposarcoma |
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https://doi.org/10.18632/oncotarget.3201
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| 10586-10591 |
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| CD163+ tumorassociated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients |
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https://doi.org/10.18632/oncotarget.3547
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| 10592-10603 |
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| Molecular profiling of peripheral blood is associated with circulating tumor cells content and poor survival in metastatic castrationresistant prostate cancer |
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https://doi.org/10.18632/oncotarget.3550
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| 10604-10616 |
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| TERT promoter mutations and telomere length in adult malignant gliomas and recurrences |
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https://doi.org/10.18632/oncotarget.3329
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| 10617-10633 |
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| Increased angiogenesis is associated with a 32gene expression signature and 6p21 amplification in aggressive endometrial cancer |
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https://doi.org/10.18632/oncotarget.3521
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| 10634-10645 |
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| High expression of cAMPresponsive elementbinding protein 1 CREB1 is associated with metastasis tumor stage and poor outcome in gastric cancer |
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https://doi.org/10.18632/oncotarget.3392
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| 10646-10657 |
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| Expression and clinicopathological significance of FSIP1 in breast cancer |
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https://doi.org/10.18632/oncotarget.3381
|
| 10658-10666 |
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