Oncotarget

VOLUME 6 (2015)

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See Milholland et al. Mutation frequency versus age in tumors of 6,969 individuals. The relationship between the two variables can be expressed as an exponential increase (P < 2.2*10-16, r = 0.36).

Table of Contents

Editorial

Ciliopathy in PCS MVA syndrome

https://doi.org/10.18632/oncotarget.5244
24582-24583
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ICOS regulates ILC2s in asthma

https://doi.org/10.18632/oncotarget.5245
24584-24585
PDF  |  How to cite

ULK1 in type I interferon response

https://doi.org/10.18632/oncotarget.5241
24586-24587
PDF  |  How to cite

RSKcFos in KSHV lytic progression

https://doi.org/10.18632/oncotarget.5262
24588-24589
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Clearance of dying cells accelerates malignancy

https://doi.org/10.18632/oncotarget.5670
24590-24591
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Gli2 hedgehog and TCR signalling

https://doi.org/10.18632/oncotarget.5017
24592-24593
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Editorial: Chromosome

Nek5: a new regulator of centrosome integrity

https://doi.org/10.18632/oncotarget.5139
24594-24595
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Progenitor cell fate SOXC and WNT

https://doi.org/10.18632/oncotarget.5237
24596-24597
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Putting the brakes on chondrosarcoma

https://doi.org/10.18632/oncotarget.5242
24598-24598
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Priority Research Papers

Quaking and miR155 interactions in inflammation and leukemogenesis

https://doi.org/10.18632/oncotarget.5248
24599-24610
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomewide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo

https://doi.org/10.18632/oncotarget.5232
24611-24626
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Agerelated somatic mutations in the cancer genome

https://doi.org/10.18632/oncotarget.5685
24627-24635
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its protumour action via extracellular matrix metalloproteases MMPs induction

https://doi.org/10.18632/oncotarget.4323
24636-24648
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers: Immunology

Eliminating roles for Tbet and IL2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors

https://doi.org/10.18632/oncotarget.5584
24649-24659
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Neuroprotective effect of cellular prion protein PrPC is related with activation of alpha7 nicotinic acetylcholine receptor α7nAchRmediated autophagy flux

https://doi.org/10.18632/oncotarget.4953
24660-24674
Abstract  |  PDF  |  Full Text  |  How to cite

Bradykinin inhibits oxidative stressinduced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/EGFR/RB signal pathways

https://doi.org/10.18632/oncotarget.5071
24675-24689
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Identification of deregulation of apoptosis and cell cycle in neuroendocrine tumors of the lung via NanoString nCounter expression analysis

https://doi.org/10.18632/oncotarget.3992
24690-24698
Abstract  |  PDF  |  Full Text  |  How to cite

Apocynin improving cardiac remodeling in chronic renal failure disease is associated with upregulation of epoxyeicosatrienoic acids

https://doi.org/10.18632/oncotarget.5084
24699-24708
Abstract  |  PDF  |  Full Text  |  How to cite

Nnbutyl haloperidol iodide protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy

https://doi.org/10.18632/oncotarget.5077
24709-24721
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ALDH1A1overexpressing cells are differentiated cells but not cancer stem or progenitor cells in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.4406
24722-24732
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

The 26S proteasome is a multifaceted target for anticancer therapies

https://doi.org/10.18632/oncotarget.4619
24733-24749
Abstract  |  PDF  |  Full Text  |  How to cite

Molecular classification of gastric cancer: Towards a pathwaydriven targeted therapy

https://doi.org/10.18632/oncotarget.4990
24750-24779
Abstract  |  PDF  |  Full Text  |  How to cite

New findings on primary and acquired resistance to antiEGFR therapy in metastatic colorectal cancer: do all roads lead to RAS

https://doi.org/10.18632/oncotarget.4959
24780-24796
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Dissecting tRNAderived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies

https://doi.org/10.18632/oncotarget.4695
24797-24822
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma

https://doi.org/10.18632/oncotarget.4485
24823-24841
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinct kinetic and mechanical properties govern mucin 16 and podocalyxinmediated tumor cell adhesion to E and Lselectin in shear flow

https://doi.org/10.18632/oncotarget.4704
24842-24855
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

https://doi.org/10.18632/oncotarget.4498
24856-24870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TERT promoter mutations contribute to IDH mutations in predicting differential responses to adjuvant therapies in WHO grade II and III diffuse gliomas

https://doi.org/10.18632/oncotarget.4549
24871-24883
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel antiGD2/41BB chimeric antigen receptor triggers neuroblastoma cell killing

https://doi.org/10.18632/oncotarget.4670
24884-24894
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A measles virus selectively blind to signaling lymphocytic activation molecule shows antitumor activity against lung cancer cells

https://doi.org/10.18632/oncotarget.4366
24895-24903
Abstract  |  PDF  |  Full Text  |  How to cite

Continuation of epidermal growth factor receptor tyrosine kinase inhibitor treatment prolongs disease control in nonsmallcell lung cancers with acquired resistance to EGFR tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.4570
24904-24911
Abstract  |  PDF  |  Full Text  |  How to cite

Overexpression of ROR2 and Wnt5a cooperatively correlates with unfavorable prognosis in patients with nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.4701
24912-24921
Abstract  |  PDF  |  Full Text  |  How to cite

Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity

https://doi.org/10.18632/oncotarget.4679
24922-24934
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MDA5 complements TLR3 in suppression of neuroblastoma

https://doi.org/10.18632/oncotarget.4511
24935-24946
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An antiEpCAM antibody EpAb26 for the treatment of colon cancer

https://doi.org/10.18632/oncotarget.4453
24947-24968
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model

https://doi.org/10.18632/oncotarget.4638
24969-24977
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Local production of the chemokines CCL5 and CXCL10 attracts CD8+ T lymphocytes into esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.4617
24978-24989
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens

https://doi.org/10.18632/oncotarget.4572
24990-25002
Abstract  |  PDF  |  Full Text  |  How to cite

Construction and analysis of lncRNAlncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer

https://doi.org/10.18632/oncotarget.4660
25003-25016
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Detection of soluble EpCAM sEpCAM in malignant ascites predicts poor overall survival in patients treated with catumaxomab

https://doi.org/10.18632/oncotarget.4496
25017-25023
Abstract  |  PDF  |  Full Text  |  How to cite

MiR215 an activator of the CTNNBIP1/βcatenin pathway is a marker of poor prognosis in human glioma

https://doi.org/10.18632/oncotarget.4622
25024-25033
Abstract  |  PDF  |  Full Text  |  How to cite

Cytosolic TMEM88 promotes triplenegative breast cancer by interacting with Dvl

https://doi.org/10.18632/oncotarget.4379
25034-25045
Abstract  |  PDF  |  Full Text  |  How to cite

A metaanalysis including doseresponse relationship between night shift work and the risk of colorectal cancer

https://doi.org/10.18632/oncotarget.4502
25046-25060
Abstract  |  PDF  |  Full Text  |  How to cite

Hepatitis B virusassociated diffuse large Bcell lymphoma: unique clinical features poor outcome and hepatitis B surface antigendriven origin

https://doi.org/10.18632/oncotarget.4677
25061-25073
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Annexin A1 is involved in the acquisition and maintenance of a stem celllike/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid

https://doi.org/10.18632/oncotarget.4725
25074-25092
Abstract  |  PDF  |  Full Text  |  How to cite

Hepatocellular carcinoma associated microRNA expression signature: integrated bioinformatics analysis experimental validation and clinical significance

https://doi.org/10.18632/oncotarget.4437
25093-25108
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis

https://doi.org/10.18632/oncotarget.4668
25109-25120
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intracellular lactatemediated induction of estrogen receptor beta ERβ in biphasic malignant pleural mesothelioma cells

https://doi.org/10.18632/oncotarget.4486
25121-25134
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Estrogen related receptor α ERRα a promising target for the therapy of adrenocortical carcinoma ACC

https://doi.org/10.18632/oncotarget.4722
25135-25148
Abstract  |  PDF  |  Full Text  |  How to cite

An isocorydine derivative dICD inhibits drug resistance by downregulating IGF2BP3 expression in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.4438
25149-25160
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coupling the modules of EMT and stemness: A tunable ‘stemness window’ model

https://doi.org/10.18632/oncotarget.4629
25161-25174
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorigenesis by Meis1 overexpression is accompanied by a change of DNA targetsequence specificity which allows binding to the AP1 element

https://doi.org/10.18632/oncotarget.4488
25175-25187
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LDOC1 silenced by cigarette exposure and involved in oral neoplastic transformation

https://doi.org/10.18632/oncotarget.4512
25188-25201
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adenomatous polyposis coli mutants dominantly activate Hsf1dependent cell stress pathways through inhibition of microtubule dynamics

https://doi.org/10.18632/oncotarget.4513
25202-25216
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Non genomic loss of function of tumor suppressors in CML: BCRABL promotes IκBα mediated p53 nuclear exclusion

https://doi.org/10.18632/oncotarget.4611
25217-25225
Abstract  |  PDF  |  Full Text  |  How to cite

Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer

https://doi.org/10.18632/oncotarget.4712
25226-25239
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes

https://doi.org/10.18632/oncotarget.4595
25240-25251
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PERK/CHOP contributes to the CGK733induced vesicular calcium sequestration which is accompanied by nonapoptotic cell death

https://doi.org/10.18632/oncotarget.4487
25252-25265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR125a suppresses tumor growth invasion and metastasis in cervical cancer by targeting STAT3

https://doi.org/10.18632/oncotarget.4457
25266-25280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RY2f an isoflavone analog overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.4634
25281-25294
Abstract  |  PDF  |  Full Text  |  How to cite

Contactdependent carcinoma aggregate dispersion by M2a macrophages via ICAM1 and β2 integrin interactions

https://doi.org/10.18632/oncotarget.4716
25295-25307
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Calmodulin antagonists promote TRA8 therapy of resistant pancreatic cancer

https://doi.org/10.18632/oncotarget.4490
25308-25319
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epithelial derived CTGF promotes breast tumor progression via inducing EMT and collagen I fibers deposition

https://doi.org/10.18632/oncotarget.4659
25320-25338
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR186

https://doi.org/10.18632/oncotarget.4509
25339-25355
Abstract  |  PDF  |  Full Text  |  How to cite

CXorf61 is a target for T cell based immunotherapy of triplenegative breast cancer

https://doi.org/10.18632/oncotarget.4516
25356-25367
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Characterization of SLC22A18 as a tumor suppressor and novel biomarker in colorectal cancer

https://doi.org/10.18632/oncotarget.4681
25368-25380
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A long noncoding RNA AB073614 promotes tumorigenesis and predicts poor prognosis in ovarian cancer

https://doi.org/10.18632/oncotarget.4541
25381-25389
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tankyrase inhibitors attenuate WNT/βcatenin signaling and inhibit growth of hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.4455
25390-25401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

KLF8 promotes tumorigenesis invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2

https://doi.org/10.18632/oncotarget.4517
25402-25417
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA940 promotes tumor cell invasion and metastasis by downregulating ZNF24 in gastric cancer

https://doi.org/10.18632/oncotarget.4456
25418-25428
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting endosialin/CD248 through antibodymediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature

https://doi.org/10.18632/oncotarget.4559
25429-25440
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

eIF3a improve cisplatin sensitivity in ovarian cancer by regulating XPC and p27Kip1 translation

https://doi.org/10.18632/oncotarget.4555
25441-25451
Abstract  |  PDF  |  Full Text  |  How to cite

Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures

https://doi.org/10.18632/oncotarget.4545
25452-25465
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells

https://doi.org/10.18632/oncotarget.4510
25466-25483
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma

https://doi.org/10.18632/oncotarget.4688
25484-25498
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Opposed expression of IKKα: loss in keratinizing carcinomas and gain in nonkeratinizing carcinomas

https://doi.org/10.18632/oncotarget.4548
25499-25505
Abstract  |  PDF  |  Full Text  |  How to cite

Thioredoxin 1 mediates TGFβinduced epithelialmesenchymal transition in salivary adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.4635
25506-25519
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines

https://doi.org/10.18632/oncotarget.4550
25520-25532
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of cMet and Bcl2 by microRNA206 activates apoptosis and inhibits tumor cell proliferation migration and colony formation

https://doi.org/10.18632/oncotarget.4575
25533-25574
Abstract  |  PDF  |  Full Text  |  How to cite

Increased SYK activity is associated with unfavorable outcome among patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.4669
25575-25587
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin

https://doi.org/10.18632/oncotarget.4436
25588-25601
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A noncanonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

https://doi.org/10.18632/oncotarget.4693
25602-25618
Abstract  |  PDF  |  Full Text  |  How to cite

Patientderived cell models as preclinical tools for genomedirected targeted therapy

https://doi.org/10.18632/oncotarget.4627
25619-25630
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic landscape of salivary gland tumors

https://doi.org/10.18632/oncotarget.4554
25631-25645
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PMLRARα protein degradation

https://doi.org/10.18632/oncotarget.4662
25646-25659
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK

https://doi.org/10.18632/oncotarget.4705
25660-25676
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

https://doi.org/10.18632/oncotarget.4499
25677-25695
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The BIM deletion polymorphism is a prognostic biomarker of EGFRTKIs response in NSCLC: A systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.4678
25696-25700
Abstract  |  PDF  |  Full Text  |  How to cite

NOP14 suppresses breast cancer progression by inhibiting NRIP1/Wnt/βcatenin pathway

https://doi.org/10.18632/oncotarget.4573
25701-25714
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reduced rate of copy number aberrations in mucinous colorectal carcinoma

https://doi.org/10.18632/oncotarget.4706
25715-25725
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TNF signaling mediates an enzalutamideinduced metastatic phenotype of prostate cancer and microenvironment cell cocultures

https://doi.org/10.18632/oncotarget.4535
25726-25740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antrodia cinnamomea alleviates cisplatininduced hepatotoxicity and enhances chemosensitivity of line1 lung carcinoma xenografted in BALB/cByJ mice

https://doi.org/10.18632/oncotarget.4348
25741-25754
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Twist promotes reprogramming of glucose metabolism in breast cancer cells through PI3K/AKT and p53 signaling pathways

https://doi.org/10.18632/oncotarget.4697
25755-25769
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Repairing of Nmustard derivative BO1055 induced DNA damage requires NER HR and MGMTdependent DNA repair mechanisms

https://doi.org/10.18632/oncotarget.4514
25770-25783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AF4 and AF4MLL mediate transcriptional elongation of 5lipoxygenase mRNA by 1 25dihydroxyvitamin D3

https://doi.org/10.18632/oncotarget.4703
25784-25800
Abstract  |  PDF  |  Full Text  |  How to cite

Survival of primary but not of cancer cells after combined Plk1HDAC inhibition

https://doi.org/10.18632/oncotarget.4445
25801-25814
Abstract  |  PDF  |  Full Text  |  How to cite

SERPINA1 is a direct estrogen receptor target gene and a predictor of survival in breast cancer patients

https://doi.org/10.18632/oncotarget.4441
25815-25827
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Understanding of tolerance in TRAILinduced apoptosis and cancelation of its machinery by αmangostin a xanthone derivative

https://doi.org/10.18632/oncotarget.4558
25828-25842
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

KMT Set7/9 affects genotoxic stress response via the Mdm2 axis

https://doi.org/10.18632/oncotarget.4584
25843-25855
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CCDC34 is upregulated in bladder cancer and regulates bladder cancer cell proliferation apoptosis and migration

https://doi.org/10.18632/oncotarget.4624
25856-25867
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of SDHD promoter mutations in various types of melanoma

https://doi.org/10.18632/oncotarget.4665
25868-25882
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ABT263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer

https://doi.org/10.18632/oncotarget.4540
25883-25896
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.4532
25897-25916
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen speciesdependent pathway

https://doi.org/10.18632/oncotarget.4542
25917-25931
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine23dioxygenase and inhibiting EMT induced by TNFα in melanoma

https://doi.org/10.18632/oncotarget.4577
25932-25942
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted or whole genome sequencing of formalin fixed tissue samples: potential applications in cancer genomics

https://doi.org/10.18632/oncotarget.4671
25943-25961
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miRNA7/21/107 contribute to HBxinduced hepatocellular carcinoma progression through suppression of maspin

https://doi.org/10.18632/oncotarget.4504
25962-25974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

5hydroxytryptamine receptor 5HT1DR promotes colorectal cancer metastasis by regulating Axin1/βcatenin/MMP7 signaling pathway

https://doi.org/10.18632/oncotarget.4543
25975-25987
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bortezomib inhibits Burkitt’s lymphoma cell proliferation by downregulating sumoylated hnRNP K and cMyc expression

https://doi.org/10.18632/oncotarget.4620
25988-26001
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival

https://doi.org/10.18632/oncotarget.4692
26002-26017
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Zoledronic acid prevents the tumorpromoting effects of mesenchymal stem cells via MCP1 dependent recruitment of macrophages

https://doi.org/10.18632/oncotarget.4658
26018-26028
Abstract  |  PDF  |  Full Text  |  How to cite

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy

https://doi.org/10.18632/oncotarget.4347
26029-26040
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ZIP4 silencing improves bone loss in pancreatic cancer

https://doi.org/10.18632/oncotarget.4667
26041-26051
Abstract  |  PDF  |  Full Text  |  How to cite

Leukemia inhibitory factor protects cholangiocarcinoma cells from druginduced apoptosis via a PI3K/AKTdependent Mcl1 activation

https://doi.org/10.18632/oncotarget.4482
26052-26064
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL8/androgen receptor AR/MMPs signals

https://doi.org/10.18632/oncotarget.4569
26065-26078
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Stemness and chemotherapeutic drug resistance induced by EIF5A2 overexpression in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.4581
26079-26089
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Src inhibitors act through different mechanisms in NonSmall Cell Lung Cancer models depending on EGFR and RAS mutational status

https://doi.org/10.18632/oncotarget.4636
26090-26103
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Folate deficiencytriggered redox pathways confer drug resistance in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.4422
26104-26118
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NFκB/RelAPKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells

https://doi.org/10.18632/oncotarget.4444
26119-26128
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias

https://doi.org/10.18632/oncotarget.4674
26129-26141
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1

https://doi.org/10.18632/oncotarget.4536
26142-26160
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing cMyc expression

https://doi.org/10.18632/oncotarget.4544
26161-26176
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Enhanced transfection efficiency and targeted delivery of selfassembling hR3dendriplexes in EGFRoverexpressing tumor cells

https://doi.org/10.18632/oncotarget.4614
26177-26191
Abstract  |  PDF  |  Full Text  |  How to cite

Combined expressional analysis bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells

https://doi.org/10.18632/oncotarget.4613
26192-26215
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA494 inhibits cell proliferation and invasion of chondrosarcoma cells in vivo and in vitro by directly targeting SOX9

https://doi.org/10.18632/oncotarget.4460
26216-26229
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

OSI027 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine both in vitro and in vivo

https://doi.org/10.18632/oncotarget.4579
26230-26241
Abstract  |  PDF  |  Full Text  |  How to cite

Prokineticin 2 PROK2 is an important factor for angiogenesis in colorectal cancer

https://doi.org/10.18632/oncotarget.4385
26242-26251
Abstract  |  PDF  |  Full Text  |  How to cite

Rhodomycin A a novel Srctargeted compound can suppress lung cancer cell progression via modulating Srcrelated pathways

https://doi.org/10.18632/oncotarget.4761
26252-26265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Small molecule inhibitors of Late SV40 Factor LSF abrogate hepatocellular carcinoma HCC: Evaluation using an endogenous HCC model

https://doi.org/10.18632/oncotarget.4656
26266-26277
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients

https://doi.org/10.18632/oncotarget.4495
26278-26290
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GLV9 a new synthetic flavonoid derivative ameliorates DSSinduced colitis against oxidative stress by upregulating Trx1 expression via activation of AMPK/FOXO3a pathway

https://doi.org/10.18632/oncotarget.4657
26291-26307
Abstract  |  PDF  |  Full Text  |  How to cite

CD44 promotes multidrug resistance by protecting Pglycoprotein from FBXO21mediated ubiquitination

https://doi.org/10.18632/oncotarget.4763
26308-26321
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An engineered TIMP2based and enediyneintegrated fusion protein for targeting MMP14 shows potent antitumor efficacy

https://doi.org/10.18632/oncotarget.4709
26322-26334
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of GALNT14 as a novel neuroblastoma predisposition gene

https://doi.org/10.18632/oncotarget.4501
26335-26346
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IKK inhibition increases bortezomib effectiveness in ovarian cancer

https://doi.org/10.18632/oncotarget.4713
26347-26358
Abstract  |  PDF  |  Full Text  |  How to cite

Specificity protein Sp transcription factors and metformin regulate expression of the long noncoding RNA HULC

https://doi.org/10.18632/oncotarget.4560
26359-26372
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AMF/PGImediated tumorigenesis through MAPKERK signaling in endometrial carcinoma

https://doi.org/10.18632/oncotarget.4708
26373-26387
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multikinase inhibitor treatment: Characterization validation and prognostic value

https://doi.org/10.18632/oncotarget.4557
26388-26399
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor necrosis targeted radiotherapy of nonsmall cell lung cancer using radioiodinated protohypericin in a mouse model

https://doi.org/10.18632/oncotarget.4568
26400-26410
Abstract  |  PDF  |  Full Text  |  How to cite

A genomewide assessment of rare copy number variants in colorectal cancer

https://doi.org/10.18632/oncotarget.4621
26411-26423
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model

https://doi.org/10.18632/oncotarget.4459
26424-26436
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protein kinase Crelated kinase 1 and 2 play an essential role in thromboxanemediated neoplastic responses in prostate cancer

https://doi.org/10.18632/oncotarget.4664
26437-26456
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1

https://doi.org/10.18632/oncotarget.4762
26457-26471
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluating blood levels of neuron specific enolase chromogranin A and circulating tumor cells as Merkel cell carcinoma biomarkers

https://doi.org/10.18632/oncotarget.4500
26472-26482
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic amplification of 9p241 targeting JAK2 PDL1 and PDL2 is enriched in highrisk triple negative breast cancer

https://doi.org/10.18632/oncotarget.4494
26483-26493
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SIRT3 inhibits prostate cancer by destabilizing oncoprotein cMYC through regulation of the PI3K/Akt pathway

https://doi.org/10.18632/oncotarget.4764
26494-26507
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomewide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma

https://doi.org/10.18632/oncotarget.4769
26508-26518
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse

https://doi.org/10.18632/oncotarget.4470
26519-26527
Abstract  |  PDF  |  Full Text  |  How to cite

Selective inhibition of histone deacetylase 2 induces p53dependent survivin downregulation through MDM2 proteasomal degradation

https://doi.org/10.18632/oncotarget.3100
26528-26540
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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