VOLUME 6 (2015)
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Heregulin, a new interactor of the telosome/shelterin complex in human telomeres.
See Menendez et al
Table of Contents
Editorial
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| APOBEC3 in papillomavirus restriction evolution and cancer progression |
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https://doi.org/10.18632/oncotarget.6324
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| 39385-39386 |
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| Cell autonomous VegfC/Vegfr3 signaling in adult neural stem cells |
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https://doi.org/10.18632/oncotarget.6325
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| 39387-39388 |
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| ASM in Alzheimer’s disease |
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https://doi.org/10.18632/oncotarget.6333
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| 39389-39390 |
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| Riskreducing surgery in BRCA 1/2 mutation carries: a point of view |
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https://doi.org/10.18632/oncotarget.6348
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| 39391-39392 |
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| Sequencing rare Tcell populations |
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https://doi.org/10.18632/oncotarget.6349
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| 39393-39394 |
Editorial: Gerotarget (Focus on Aging)
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| Measuring refractive index distribution in the human eye lens |
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https://doi.org/10.18632/oncotarget.6322
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| 39395-39395 |
Editorial: Autophagy and Cell Death
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| Defective autophagy gets to the brain |
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https://doi.org/10.18632/oncotarget.6318
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| 39396-39397 |
Research Perspectives
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| Metformin for cancer and aging prevention: is it a time to make the long story short |
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https://doi.org/10.18632/oncotarget.6347
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| 39398-39407 |
Priority Research Papers
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| Heregulin a new interactor of the telosome/shelterin complex in human telomeres |
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https://doi.org/10.18632/oncotarget.4962
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| 39408-39421 |
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| Heregulin a new regulator of telomere length in human cells |
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https://doi.org/10.18632/oncotarget.4964
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| 39422-39436 |
Research Papers: Gerotarget (Focus on Aging)
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| Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer’s disease: identification of common and distinct olfactory targets across Alzheimerrelated copathologies |
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https://doi.org/10.18632/oncotarget.6254
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| 39437-39456 |
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| Changes in autophagy proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells |
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https://doi.org/10.18632/oncotarget.6277
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| 39457-39468 |
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| Mitochondriatargeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats |
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https://doi.org/10.18632/oncotarget.5783
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| 39469-39481 |
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| Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their antitumor activity |
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https://doi.org/10.18632/oncotarget.5430
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| 39482-39492 |
Research Papers: Pathology
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| The redox sensitive glycogen synthase kinase 3β suppresses the selfprotective antioxidant response in podocytes upon oxidative glomerular injury |
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https://doi.org/10.18632/oncotarget.6303
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| 39493-39506 |
Research Papers: Chromosome
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| A novel gammaretroviral shuttle vector insertional mutagenesis screen identifies <em>SHARPIN</em> as a breast cancer metastasis gene and prognostic biomarker |
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https://doi.org/10.18632/oncotarget.6232
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| 39507-39520 |
Reviews
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| Novel agents for advanced pancreatic cancer |
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https://doi.org/10.18632/oncotarget.3999
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| 39521-39537 |
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| Influence of companion diagnostics on efficacy and safety of targeted anticancer drugs: systematic review and metaanalyses |
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https://doi.org/10.18632/oncotarget.5946
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| 39538-39549 |
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| Differentiation and transdifferentiation potentials of cancer stem cells |
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https://doi.org/10.18632/oncotarget.6098
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| 39550-39563 |
Research Papers
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| Multistep effective drug distribution within solid tumors |
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https://doi.org/10.18632/oncotarget.5051
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| 39564-39577 |
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| Epithelial neoplasia coincides with exacerbated injury and fibrotic response in the lungs of <i>Gprc5a</i>knockout mice following silica exposure |
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https://doi.org/10.18632/oncotarget.5532
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| 39578-39593 |
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| Silibinin enhances the repair of ultraviolet Binduced DNA damage by activating p53dependent nucleotide excision repair mechanism in human dermal fibroblasts |
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https://doi.org/10.18632/oncotarget.5519
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| 39594-39606 |
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| Molecular pathological epidemiology of colorectal cancer in Chinese patients with <i>KRAS</i> and <i>BRAF</i> mutations |
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https://doi.org/10.18632/oncotarget.5551
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| 39607-39613 |
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| Systematic evaluation of underlying defects in DNA repair as an approach to caseonly assessment of familial prostate cancer |
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https://doi.org/10.18632/oncotarget.5554
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| 39614-39633 |
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| Mutant AKT1E17K is oncogenic in lung epithelial cells |
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https://doi.org/10.18632/oncotarget.4022
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| 39634-39650 |
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| <i>IDH1</i> mutation detection by droplet digital PCR in glioma |
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https://doi.org/10.18632/oncotarget.5630
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| 39651-39660 |
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| MiR652 inhibits acidic microenvironmentinduced epithelialmesenchymal transition of pancreatic cancer cells by targeting ZEB1 |
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https://doi.org/10.18632/oncotarget.5350
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| 39661-39675 |
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| Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia angiogenesis and inflammation responses |
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https://doi.org/10.18632/oncotarget.5344
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| 39676-39691 |
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| CGK733induced LC3 II formation is positively associated with the expression of cyclindependent kinase inhibitor p21<sup>Waf1/Cip1</sup> through modulation of the AMPK and PERK/CHOP signaling pathways |
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https://doi.org/10.18632/oncotarget.5625
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| 39692-39701 |
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| mTOR inhibitors sensitize thyroid cancer cells to cytotoxic effect of vemurafenib |
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https://doi.org/10.18632/oncotarget.4052
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| 39702-39713 |
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| Suppressing NRIP1 inhibits growth of breast cancer cells <i>in vitro</i> and <i>in vivo</i> |
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https://doi.org/10.18632/oncotarget.5356
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| 39714-39724 |
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| Practice of traditional Chinese medicine for psychobehavioral intervention improves quality of life in cancer patients: A systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.5388
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| 39725-39739 |
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| Overexpression of CHI3L1 is associated with chemoresistance and poor outcome of epithelial ovarian carcinoma |
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https://doi.org/10.18632/oncotarget.5469
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| 39740-39755 |
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| HsamiR1395p inhibits proliferation and causes apoptosis associated with downregulation of cMet |
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https://doi.org/10.18632/oncotarget.5476
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| 39756-39792 |
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| LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns |
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https://doi.org/10.18632/oncotarget.5794
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| 39793-39805 |
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| Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer – a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation |
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https://doi.org/10.18632/oncotarget.5655
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| 39806-39820 |
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| Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer |
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https://doi.org/10.18632/oncotarget.5496
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| 39821-39838 |
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| Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.5674
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| 39839-39854 |
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| Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers |
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https://doi.org/10.18632/oncotarget.5627
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| 39855-39864 |
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| Long noncoding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations |
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https://doi.org/10.18632/oncotarget.5399
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| 39865-39876 |
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| IGF1R inhibition induces scheduledependent sensitization of human melanoma to temozolomide |
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https://doi.org/10.18632/oncotarget.5631
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| 39877-39890 |
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| INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas |
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https://doi.org/10.18632/oncotarget.5359
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| 39891-39907 |
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| Frizzled7 promoter is highly active in tumors and promoterdriven Shigalike toxin I inhibits hepatocellular carcinoma growth |
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https://doi.org/10.18632/oncotarget.5516
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| 39908-39923 |
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| Key contribution of eIF4Hmediated translational control in tumor promotion |
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https://doi.org/10.18632/oncotarget.5442
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| 39924-39940 |
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| Prostaglandins induce early growth response 1 transcription factor mediated microsomal prostaglandin E<sub>2</sub> synthase upregulation for colorectal cancer progression |
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https://doi.org/10.18632/oncotarget.5402
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| 39941-39959 |
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| Impact of wall shear stress and ligand avidity on binding of antiCD146coated nanoparticles to murine tumor endothelium under flow |
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https://doi.org/10.18632/oncotarget.5662
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| 39960-39968 |
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| Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif |
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https://doi.org/10.18632/oncotarget.5483
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| 39969-39979 |
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| The 5′untranslated region of p16<sup>INK4</sup>a melanoma tumor suppressor acts as a cellular IRES controlling mRNA translation under hypoxia through YBX1 binding |
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https://doi.org/10.18632/oncotarget.5387
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| 39980-39994 |
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| Polymorphisms involving gain or loss of CpG sites are significantly enriched in traitassociated SNPs |
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https://doi.org/10.18632/oncotarget.5650
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| 39995-40004 |
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| A multistage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and proinflammatory secretory phenotype |
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https://doi.org/10.18632/oncotarget.5552
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| 40005-40025 |
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| PIK3CA mutation detection in metastatic biliary cancer using cellfree DNA |
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https://doi.org/10.18632/oncotarget.5432
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| 40026-40035 |
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| Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells |
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https://doi.org/10.18632/oncotarget.5486
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| 40036-40052 |
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| LGR5 regulates prosurvival MEK/ERK and proliferative Wnt/βcatenin signalling in neuroblastoma |
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https://doi.org/10.18632/oncotarget.5548
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| 40053-40067 |
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| The herbal compound Songyou Yin SYY inhibits hepatocellular carcinoma growth and improves survival in models of chronic fibrosis via paracrine inhibition of activated hepatic stellate cells |
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https://doi.org/10.18632/oncotarget.5313
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| 40068-40080 |
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| Aberrant high expression of immunoglobulin G in epithelial stem/progenitorlike cells contributes to tumor initiation and metastasis |
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https://doi.org/10.18632/oncotarget.5542
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| 40081-40094 |
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| Expression of young HERVH loci in the course of colorectal carcinoma and correlation with molecular subtypes |
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https://doi.org/10.18632/oncotarget.5539
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| 40095-40111 |
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| Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma |
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https://doi.org/10.18632/oncotarget.5556
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| 40112-40126 |
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| Comparative effectiveness study of breastconserving surgery and mastectomy in the general population: A NCDB analysis |
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https://doi.org/10.18632/oncotarget.5394
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| 40127-40140 |
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| The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2V617Fdriven cells and inhibit colony formation of primary MPN cells |
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https://doi.org/10.18632/oncotarget.5653
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| 40141-40157 |
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| Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer |
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https://doi.org/10.18632/oncotarget.5522
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| 40158-40171 |
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| Potential involvement of miR375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5 |
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https://doi.org/10.18632/oncotarget.5502
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| 40172-40185 |
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| Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq |
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https://doi.org/10.18632/oncotarget.5529
|
| 40186-40201 |
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| Ligandbased chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying <i>in vitro</i> efficacy against melanoma cells |
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https://doi.org/10.18632/oncotarget.5473
|
| 40202-40222 |
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| Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5540
|
| 40223-40234 |
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| Genes with stable DNA methylation levels show higher evolutionary conservation than genes with fluctuant DNA methylation levels |
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https://doi.org/10.18632/oncotarget.5504
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| 40235-40246 |
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| ERβ regulation of NFkB activation in prostate cancer is mediated by HIF1 |
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https://doi.org/10.18632/oncotarget.5377
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| 40247-40254 |
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| Targeting stemness is an effective strategy to control <i>EML4ALK</i>+ nonsmall cell lung cancer cells |
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https://doi.org/10.18632/oncotarget.5434
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| 40255-40267 |
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| Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines |
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https://doi.org/10.18632/oncotarget.5592
|
| 40268-40282 |
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| Identification of CD146 as a marker enriched for tumorpropagating capacity reveals targetable pathways in primary human sarcoma |
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https://doi.org/10.18632/oncotarget.5375
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| 40283-40294 |
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| Changes in microRNA miRNA expression during pancreatic cancer development and progression in a genetically engineered Kras<sup>G12D</sup>;Pdx1Cre mouse KC model |
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https://doi.org/10.18632/oncotarget.5641
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| 40295-40309 |
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| Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion |
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https://doi.org/10.18632/oncotarget.5643
|
| 40310-40326 |
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| Genomewide association study identifies two new susceptibility loci for colorectal cancer at 5q233 and 17q12 in Han Chinese |
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https://doi.org/10.18632/oncotarget.5530
|
| 40327-40336 |
Clinical Research Papers
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| Threedimensional structure discrepancy between HLA alleles for effective prediction of aGVHD severity and optimal selection of recipientdonor pairs: a proofofconcept study |
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https://doi.org/10.18632/oncotarget.5378
|
| 40337-40359 |
|
| Prospective blinded study of somatic mutation detection in cellfree DNA utilizing a targeted 54gene next generation sequencing panel in metastatic solid tumor patients |
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https://doi.org/10.18632/oncotarget.5465
|
| 40360-40369 |
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| Overexpression of caldesmon is associated with tumor progression in patients with primary nonmuscleinvasive bladder cancer |
|
https://doi.org/10.18632/oncotarget.5458
|
| 40370-40384 |
Errata
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| Erratum: A novel cancer immunotherapy based on the combination of a synthetic carbohydratepulsed dendritic cell vaccine and glycoengineered cancer cells |
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https://doi.org/10.18632/oncotarget.6369
|
| 40385-40385 |
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