VOLUME 6 (2015)
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Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras.
See Sung et al.
Table of Contents
Editorial
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| Immune evasion mechanisms of arenaviruses |
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https://doi.org/10.18632/oncotarget.6367
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| 40386-40387 |
Priority Research Papers
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| A new class of small molecule estrogen receptoralpha antagonists that overcome antiestrogen resistance |
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https://doi.org/10.18632/oncotarget.6323
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| 40388-40404 |
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| Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras |
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https://doi.org/10.18632/oncotarget.6334
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| 40405-40417 |
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| Genomic binding and regulation of gene expression by the thyroid carcinomaassociated PAX8PPARG fusion protein |
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https://doi.org/10.18632/oncotarget.6340
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| 40418-40432 |
Research Papers: Pathology
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| <em>In vivo</em> regeneration of renal vessels post whole decellularized kidneys transplantation |
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https://doi.org/10.18632/oncotarget.6321
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| 40433-40442 |
Research Papers: Immunology
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| Linking estrogen receptor β expression with inflammatory bowel disease activity |
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https://doi.org/10.18632/oncotarget.6217
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| 40443-40451 |
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| Myelin oligodendrocyte glycoprotein MOG<sub>3555</sub>induced experimental autoimmune encephalomyelitis is ameliorated in interleukin32 alpha transgenic mice |
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https://doi.org/10.18632/oncotarget.6306
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| 40452-40463 |
Research Papers: Chromosome
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| Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells |
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https://doi.org/10.18632/oncotarget.6342
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| 40464-40479 |
Reviews
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| Deconvoluting the complexity of autophagy and Parkinson’s disease for potential therapeutic purpose |
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https://doi.org/10.18632/oncotarget.5803
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| 40480-40495 |
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| Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction |
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https://doi.org/10.18632/oncotarget.5800
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| 40496-40506 |
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| Vascular heterogeneity and targeting: the role of YKL40 in glioblastoma vascularization |
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https://doi.org/10.18632/oncotarget.5943
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| 40507-40518 |
Research Papers
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| Identification of shortform RON as a novel intrinsic resistance mechanism for antiMET therapy in METpositive gastric cancer |
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https://doi.org/10.18632/oncotarget.5816
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| 40519-40534 |
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| Overexpression of Mcl1 confers resistance to BRAF<sup>V600E</sup> inhibitors alone and in combination with MEK1/2 inhibitors in melanoma |
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https://doi.org/10.18632/oncotarget.5755
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| 40535-40556 |
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| Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 and p16ink4 mRNA |
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https://doi.org/10.18632/oncotarget.5829
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| 40557-40574 |
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| Exosomes enriched in stemness/metastaticrelated mRNAS promote oncogenic potential in breast cancer |
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https://doi.org/10.18632/oncotarget.5818
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| 40575-40587 |
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| Wholeexome sequencing and genomewide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome |
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https://doi.org/10.18632/oncotarget.5845
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| 40588-40597 |
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| Novel C6substituted 134oxadiazinones as potential anticancer agents |
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https://doi.org/10.18632/oncotarget.5839
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| 40598-40610 |
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| Identification of specific DNA methylation sites on the Ychromosome as biomarker in prostate cancer |
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https://doi.org/10.18632/oncotarget.6141
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| 40611-40621 |
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| Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5872
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| 40622-40641 |
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| Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine |
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https://doi.org/10.18632/oncotarget.5841
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| 40642-40654 |
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| Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2 |
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https://doi.org/10.18632/oncotarget.5821
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| 40655-40666 |
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| Doxycycline reverses epithelialtomesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells |
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https://doi.org/10.18632/oncotarget.5842
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| 40667-40679 |
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| Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alphafetoprotein <i>in vitro</i> and <i>in vivo</i> involving the NFkappaB and the betacatenin pathways |
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https://doi.org/10.18632/oncotarget.5673
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| 40680-40691 |
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| A novel chemical STF083010 reverses tamoxifenrelated drug resistance in breast cancer by inhibiting IRE1/XBP1 |
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https://doi.org/10.18632/oncotarget.5827
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| 40692-40703 |
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| <i>UCHL1</i> is a biomarker of aggressive multiple myeloma required for disease progression |
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https://doi.org/10.18632/oncotarget.5727
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| 40704-40718 |
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| Interleukin 6 trigged ataxiatelangiectasia mutated activation facilitates lung cancer metastasis via MMP3/MMP13 upregulation |
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https://doi.org/10.18632/oncotarget.5825
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| 40719-40733 |
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| Molecular mechanisms of cisplatin cytotoxicity in acute promyelocytic leukemia cells |
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https://doi.org/10.18632/oncotarget.5754
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| 40734-40746 |
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| IL32θ gene expression in acute myeloid leukemia suppresses TNFα production |
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https://doi.org/10.18632/oncotarget.5688
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| 40747-40761 |
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| A biotherapy based on PSCsin3D spheroidameliorated biologics depletes <i>in vivo</i> cancersustaining stem cells |
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https://doi.org/10.18632/oncotarget.5691
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| 40762-40774 |
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| CUDR promotes liver cancer stem cell growth through upregulating TERT and CMyc |
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https://doi.org/10.18632/oncotarget.5805
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| 40775-40798 |
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| MicroRNA29B mir29b regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3 |
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https://doi.org/10.18632/oncotarget.5695
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| 40799-40814 |
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| A set of defined oncogenic mutation alleles seems to better predict the response to cetuximab in CRC patientderived xenograft than KRAS 12/13 mutations |
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https://doi.org/10.18632/oncotarget.5886
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| 40815-40821 |
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| Active glycolytic metabolism in CD133+ hepatocellular cancer stem cells: regulation by MIR122 |
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https://doi.org/10.18632/oncotarget.5812
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| 40822-40835 |
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| Distribution and prognostic relevance of tumorinfiltrating lymphocytes TILs and PD1/PDL1 immune checkpoints in human brain metastases |
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https://doi.org/10.18632/oncotarget.5696
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| 40836-40849 |
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| Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/Pglycoproteinoverexpressing cancer cells |
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https://doi.org/10.18632/oncotarget.5813
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| 40850-40865 |
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| Biscyclopropane analog of disorazole C<sub>1</sub> is a microtubuledestabilizing agent active in ABCB1overexpressing human colon cancer cells |
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https://doi.org/10.18632/oncotarget.5885
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| 40866-40879 |
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| Amphiregulin enhances intercellular adhesion molecule1 expression and promotes tumor metastasis in human osteosarcoma |
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https://doi.org/10.18632/oncotarget.5679
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| 40880-40895 |
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| IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry |
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https://doi.org/10.18632/oncotarget.5683
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| 40896-40906 |
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| Disulfiram inhibits TGFβinduced epithelialmesenchymal transition and stemlike features in breast cancer via ERK/NFκB/Snail pathway |
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https://doi.org/10.18632/oncotarget.5723
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| 40907-40919 |
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| Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5712
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| 40920-40933 |
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| Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney |
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https://doi.org/10.18632/oncotarget.5882
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| 40934-40939 |
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| Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5724
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| 40940-40952 |
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| ÂÂPrevalence of deleterious <em>ATM</em> germline mutations in gastric cancer patients |
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https://doi.org/10.18632/oncotarget.5944
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| 40953-40958 |
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| PTTG regulates the metabolic switch of ovarian cancer cells via the cmyc pathway |
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https://doi.org/10.18632/oncotarget.5726
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| 40959-40969 |
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| Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin |
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https://doi.org/10.18632/oncotarget.5403
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| 40970-40980 |
|
| The Hsp90 inhibitor SNX7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human p53negative chronic lymphocytic leukemia |
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https://doi.org/10.18632/oncotarget.5715
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| 40981-40997 |
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| Heterogeneous glioblastoma cell crosstalk promotes phenotype alterations and enhanced drug resistance |
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https://doi.org/10.18632/oncotarget.5701
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| 40998-41017 |
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| Anticancer efficacy of SREBP inhibitor alone or in combination with docetaxel in prostate cancer harboring p53 mutations |
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https://doi.org/10.18632/oncotarget.5879
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| 41018-41032 |
|
| The copy number of EpsteinBarr virus latent genome correlates with the oncogenicity by the activation level of LMP1 and NFκB |
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https://doi.org/10.18632/oncotarget.5708
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| 41033-41044 |
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| LncRNA <i>MALAT1</i> enhances oncogenic activities of EZH2 in castrationresistant prostate cancer |
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https://doi.org/10.18632/oncotarget.5728
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| 41045-41055 |
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| YpT12N0 rectal cancer after neoadjuvant chemoradiation has lower survival compared with pT12N0 rectal cancer |
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https://doi.org/10.18632/oncotarget.5379
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| 41056-41062 |
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| Inhibition of Eph receptor A4 by 25dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice |
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https://doi.org/10.18632/oncotarget.5729
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| 41063-41076 |
|
| Epigenetic downregulation of the ISG15–conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.6218
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| 41077-41091 |
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| CMTM7 knockdown increases tumorigenicity of human nonsmall cell lung cancer cells and EGFRAKT signaling by reducing Rab5 activation |
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https://doi.org/10.18632/oncotarget.5732
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| 41092-41107 |
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| Germline variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients |
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https://doi.org/10.18632/oncotarget.5694
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| 41108-41122 |
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| Chemical probing of HER2amplified cancer cells identifies TORC2 as a particularly effective secondary target for combination with lapatinib |
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https://doi.org/10.18632/oncotarget.5660
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| 41123-41133 |
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| Ki67/SATB1 ratio is an independent prognostic factor of overall survival in patients with early hormone receptorpositive invasive ductal breast carcinoma |
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https://doi.org/10.18632/oncotarget.5838
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| 41134-41145 |
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| Silibininmediated metabolic reprogramming attenuates pancreatic cancerinduced cachexia and tumor growth |
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https://doi.org/10.18632/oncotarget.5843
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| 41146-41161 |
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| P2X3 purinergic receptor overexpression is associated with poor recurrencefree survival in hepatocellular carcinoma patients |
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https://doi.org/10.18632/oncotarget.6240
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| 41162-41179 |
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| Isothiocyanatostilbenes as novel cMet inhibitors |
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https://doi.org/10.18632/oncotarget.5748
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| 41180-41193 |
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| Tetracyclineinducible shRNA targeting long noncoding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells |
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https://doi.org/10.18632/oncotarget.5880
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| 41194-41203 |
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| Morphometric analysis of immunoselection against hyperploid cancer cells |
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https://doi.org/10.18632/oncotarget.5400
|
| 41204-41215 |
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| Identifying clinically relevant drug resistance genes in druginduced resistant cancer cell lines and postchemotherapy tissues |
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https://doi.org/10.18632/oncotarget.5649
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| 41216-41227 |
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| Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myeloma |
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https://doi.org/10.18632/oncotarget.5682
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| 41228-41236 |
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| Novel insights into Notum and glypicans regulation in colorectal cancer |
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https://doi.org/10.18632/oncotarget.5652
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| 41237-41257 |
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| Peptide mediated active targeting and intelligent particle size reductionmediated enhanced penetrating of fabricated nanoparticles for triplenegative breast cancer treatment |
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https://doi.org/10.18632/oncotarget.5692
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| 41258-41274 |
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| Junctional adhesion moleculeA is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus |
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https://doi.org/10.18632/oncotarget.5753
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| 41275-41289 |
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| TIP60miR22 axis as a prognostic marker of breast cancer progression |
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https://doi.org/10.18632/oncotarget.5636
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| 41290-41306 |
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| E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling |
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https://doi.org/10.18632/oncotarget.5846
|
| 41307-41323 |
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| Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase8/TRAF2mediated signaling |
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https://doi.org/10.18632/oncotarget.5847
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| 41324-41338 |
Clinical Research Papers
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| A phase I clinical trial utilizing autologous tumorinfiltrating lymphocytes in patients with primary hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5463
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| 41339-41349 |
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| The prognostic value of peripheral CD4<sup>+</sup>CD25<sup>+</sup> T lymphocytes among early stage and triple negative breast cancer patients receiving dendritic cellscytokine induced killer cells infusion |
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https://doi.org/10.18632/oncotarget.5534
|
| 41350-41359 |
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| <em>ALDH1A1</em> mRNA expression in association with prognosis of triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.6023
|
| 41360-41369 |
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| Prognostic significance of the combination of preoperative hemoglobin albumin lymphocyte and platelet in patients with gastric carcinoma: a retrospective cohort study |
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https://doi.org/10.18632/oncotarget.5629
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| 41370-41382 |
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| A novel prognostic biomarker SPC24 upregulated in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.5510
|
| 41383-41397 |
Errata
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| Erratum: Bisphosphonateinduced differential modulation of immune cell function in gingiva and bone marrow <em>in vivo</em>: Role in osteoclastmediated NK cell activation |
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https://doi.org/10.18632/oncotarget.6431
|
| 41398 |
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