VOLUME 6 (2015)
View Archive »
About The Cover
Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex. See Fischer et al.
|
|
Table of Contents
Editorial
|
| SnoRNPs ZNHIT proteins and the R2TP pathway |
|
https://doi.org/10.18632/oncotarget.6388
|
| 41399-41400 |
Editorial: Chromosome
|
| Active transcription without histone modifications |
|
https://doi.org/10.18632/oncotarget.6437
|
| 41401-41401 |
Priority Research Papers
|
| Indirect p53dependent transcriptional repression of Survivin CDC25C and PLK1 genes requires the cyclindependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex |
|
https://doi.org/10.18632/oncotarget.6356
|
| 41402-41417 |
Research Papers: Gerotarget (Focus on Aging)
|
| Genomewide endogenous DAF16/FOXO recruitment dynamics during lowered insulin signalling in C elegans |
|
https://doi.org/10.18632/oncotarget.6282
|
| 41418-41433 |
Research Papers: Pathology
|
| LPSinduced TNFα factor mediates proinflammatory and profibrogenic pattern in nonalcoholic fatty liver disease |
|
https://doi.org/10.18632/oncotarget.5163
|
| 41434-41452 |
|
| VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer |
|
https://doi.org/10.18632/oncotarget.6162
|
| 41453-41463 |
|
| Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro |
|
https://doi.org/10.18632/oncotarget.6203
|
| 41464-41478 |
|
| Myristic acid potentiates palmitic acidinduced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis |
|
https://doi.org/10.18632/oncotarget.6286
|
| 41479-41496 |
|
| Donorderived stemcells and epithelial mesenchymal transition in squamous cell carcinoma in transplant recipients |
|
https://doi.org/10.18632/oncotarget.6359
|
| 41497-41507 |
Research Papers: Immunology
|
| 4Hydroxynonenal regulates mitochondrial function in human small airway epithelial cells |
|
https://doi.org/10.18632/oncotarget.6131
|
| 41508-41521 |
Research Papers: Autophagy and Cell Death
|
| Differential role of RIP1 in Smac mimeticmediated chemosensitization of neuroblastoma cells |
|
https://doi.org/10.18632/oncotarget.6308
|
| 41522-41534 |
|
| Mechanisms for autophagy modulation by isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells |
|
https://doi.org/10.18632/oncotarget.6365
|
| 41535-41549 |
Research Papers: Chromosome
|
| ASPP1/2PP1 complexes are required for chromosome segregation and kinetochoremicrotubule attachments |
|
https://doi.org/10.18632/oncotarget.6355
|
| 41550-41565 |
Reviews
|
| The dark side of ZNF217 a key regulator of tumorigenesis with powerful biomarker value |
|
https://doi.org/10.18632/oncotarget.5893
|
| 41566-41581 |
|
| Decoding Warburg’s hypothesis: tumorrelated mutations in the mitochondrial respiratory chain |
|
https://doi.org/10.18632/oncotarget.6057
|
| 41582-41599 |
|
| Concepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapies |
|
https://doi.org/10.18632/oncotarget.6113
|
| 41600-41619 |
Research Papers
|
| MiR2243p inhibits hypoxiainduced autophagy by targeting autophagyrelated genes in human glioblastoma cells |
|
https://doi.org/10.18632/oncotarget.5871
|
| 41620-41637 |
|
| MicroRNA1 downregulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/βcatenin pathway |
|
https://doi.org/10.18632/oncotarget.5873
|
| 41638-41649 |
|
| The proinflammatory LTB4/BLT1 signal axis confers resistance to TGFβ1induced growth inhibition by targeting Smad3 linker region |
|
https://doi.org/10.18632/oncotarget.6146
|
| 41650-41666 |
|
| Eribulin targets a chTOGdependent directed migration of cancer cells |
|
https://doi.org/10.18632/oncotarget.6147
|
| 41667-41678 |
|
| Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP1/cJun and NFκB pathway |
|
https://doi.org/10.18632/oncotarget.6149
|
| 41679-41691 |
|
| Mutant p53 confers chemoresistance in nonsmall cell lung cancer by upregulating Nrf2 |
|
https://doi.org/10.18632/oncotarget.6150
|
| 41692-41705 |
|
| 5Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stemlike traits |
|
https://doi.org/10.18632/oncotarget.5991
|
| 41706-41721 |
|
| Suppression of ATAD2 inhibits hepatocellular carcinoma progression through activation of p53 and p38mediated apoptotic signaling |
|
https://doi.org/10.18632/oncotarget.6152
|
| 41722-41735 |
|
| A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway |
|
https://doi.org/10.18632/oncotarget.6153
|
| 41736-41749 |
|
| A novel prohibitinbinding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation |
|
https://doi.org/10.18632/oncotarget.6154
|
| 41750-41765 |
|
| EBVmiRBART103p facilitates epithelialmesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC |
|
https://doi.org/10.18632/oncotarget.6155
|
| 41766-41782 |
|
| Transient receptor potential melastatin 4 channel contributes to migration of androgeninsensitive prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.6157
|
| 41783-41793 |
|
| Palbociclib inhibits epithelialmesenchymal transition and metastasis in breast cancer via cJun/COX2 signaling pathway |
|
https://doi.org/10.18632/oncotarget.5993
|
| 41794-41808 |
|
| Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model |
|
https://doi.org/10.18632/oncotarget.6166
|
| 41809-41824 |
|
| Combination of circulating tumor cell enumeration and tumor marker detection in predicting prognosis and treatment effect in metastatic castrationresistant prostate cancer |
|
https://doi.org/10.18632/oncotarget.6167
|
| 41825-41836 |
|
| Insulinlike growth factorindependent insulinlike growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1 |
|
https://doi.org/10.18632/oncotarget.5995
|
| 41837-41855 |
|
| Adjuvant treatment with tumortargeting Salmonella typhimurium A1R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model |
|
https://doi.org/10.18632/oncotarget.6170
|
| 41856-41862 |
|
| Inhibition of iNOS activity enhances the antitumor effects of alphagalactosylceramide in established murine cancer model |
|
https://doi.org/10.18632/oncotarget.6172
|
| 41863-41874 |
|
| The demographic features clinicopathologic characteristics treatment outcome and diseasespecific prognostic factors of solitary fibrous tumor: a populationbased analysis |
|
https://doi.org/10.18632/oncotarget.6174
|
| 41875-41883 |
|
| Caveolin1negative head and neck squamous cell carcinoma primary tumors display increased epithelial to mesenchymal transition and prometastatic properties |
|
https://doi.org/10.18632/oncotarget.6099
|
| 41884-41901 |
|
| BclxL inhibition by moleculartargeting drugs sensitizes human pancreatic cancer cells to TRAIL |
|
https://doi.org/10.18632/oncotarget.5881
|
| 41902-41915 |
|
| GalNAcT14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.6019
|
| 41916-41928 |
|
| E4335dimethoxyphenylallyl2methoxyphenol inhibits growth of colon tumors in mice |
|
https://doi.org/10.18632/oncotarget.5861
|
| 41929-41943 |
|
| STAT3 blockade enhances the efficacy of conventional chemotherapeutic agents by eradicating head neck stemloid cancer cell |
|
https://doi.org/10.18632/oncotarget.5986
|
| 41944-41958 |
|
| Cullin3 promotes breast cancer cells metastasis and epithelialmesenchymal transition by targeting BRMS1 for degradation |
|
https://doi.org/10.18632/oncotarget.5999
|
| 41959-41975 |
|
| Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castratesensitive and resistant prostate cancer |
|
https://doi.org/10.18632/oncotarget.5659
|
| 41976-41987 |
|
| Mitochondrial DNA copy number in peripheral blood leukocytes and the aggressiveness of localized prostate cancer |
|
https://doi.org/10.18632/oncotarget.5889
|
| 41988-41996 |
|
| Oncogenic Ras suppresses ING4TDGFas axis to promote apoptosis resistance |
|
https://doi.org/10.18632/oncotarget.6015
|
| 41997-42007 |
|
| Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma |
|
https://doi.org/10.18632/oncotarget.5788
|
| 42008-42018 |
|
| CD133 overexpression correlates with clinicopathological features of gastric cancer patients and its impact on survival: a systematic review and metaanalysis |
|
https://doi.org/10.18632/oncotarget.5714
|
| 42019-42027 |
|
| Cancertestis antigen MAGEC2 binds Rbx1 and inhibits ubiquitin ligasemediated turnover of cyclin E |
|
https://doi.org/10.18632/oncotarget.5973
|
| 42028-42039 |
|
| Comprehensive profiling of novel microRNA9 targets and a tumor suppressor role of microRNA9 via targeting IGF2BP1 in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.5969
|
| 42040-42052 |
|
| MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data |
|
https://doi.org/10.18632/oncotarget.5974
|
| 42053-42066 |
|
| PD1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.5955
|
| 42067-42080 |
|
| Imaging the distribution of an antibodydrug conjugate constituent targeting mesothelin with 89Zr and IRDye 800CW in mice bearing human pancreatic tumor xenografts |
|
https://doi.org/10.18632/oncotarget.5877
|
| 42081-42090 |
|
| Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model |
|
https://doi.org/10.18632/oncotarget.5990
|
| 42091-42104 |
|
| Silencing P2X7 receptor downregulates the expression of TCP1 involved in lymphoma lymphatic metastasis |
|
https://doi.org/10.18632/oncotarget.5870
|
| 42105-42117 |
|
| LRG1 expression indicates unfavorable clinical outcome in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.5967
|
| 42118-42129 |
|
| Crosstalk between chronic lymphocytic leukemia CLL tumor B cells and mesenchymal stromal cells MSCs: implications for neoplastic cell survival |
|
https://doi.org/10.18632/oncotarget.6239
|
| 42130-42149 |
|
| Codelivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEGPLGA copolymer nanoparticles for the treatment of nonsmall lung cancer |
|
https://doi.org/10.18632/oncotarget.6243
|
| 42150-42168 |
|
| Correlation of clinical features and genetic profiles of stromal interaction molecule 1 STIM1 in colorectal cancers |
|
https://doi.org/10.18632/oncotarget.5888
|
| 42169-42182 |
|
| Mutant HRAS as novel target for MEK and mTOR inhibitors |
|
https://doi.org/10.18632/oncotarget.5619
|
| 42183-42196 |
|
| Senseantisense genepairs in breast cancer and associated pathological pathways |
|
https://doi.org/10.18632/oncotarget.6255
|
| 42197-42221 |
|
| New tumor regression grade for rectal cancer after neoadjuvant therapy and radical surgery |
|
https://doi.org/10.18632/oncotarget.6008
|
| 42222-42231 |
|
| Combinatorial BTK and MALT1 inhibition augments killing of CD79 mutant diffuse large B cell lymphoma |
|
https://doi.org/10.18632/oncotarget.6273
|
| 42232-42242 |
|
| Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors GIST beyond KIT/PDGFRα genotype evaluated by next generation sequencing NGS |
|
https://doi.org/10.18632/oncotarget.6278
|
| 42243-42257 |
|
| A Polycombmir200 loop regulates clinical outcome in bladder cancer |
|
https://doi.org/10.18632/oncotarget.5546
|
| 42258-42275 |
|
| Involvement of Wnt/βcatenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma |
|
https://doi.org/10.18632/oncotarget.5514
|
| 42276-42289 |
|
| Controllable permeability of bloodbrain barrier and reduced brain injury through lowintensity pulsed ultrasound stimulation |
|
https://doi.org/10.18632/oncotarget.5978
|
| 42290-42299 |
|
| Clinical significance of high cMYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia |
|
https://doi.org/10.18632/oncotarget.5982
|
| 42300-42311 |
|
| Germline HOXB13 pGly84Glu mutation and cancer susceptibility: a pooled analysis of 25 epidemiological studies with 145257 participates |
|
https://doi.org/10.18632/oncotarget.5994
|
| 42312-42321 |
|
| Fusarochromanoneinduced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5 |
|
https://doi.org/10.18632/oncotarget.5996
|
| 42322-42333 |
|
| Mutational profiling of colorectal cancers with microsatellite instability |
|
https://doi.org/10.18632/oncotarget.5997
|
| 42334-42344 |
Clinical Research Papers
|
| IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association |
|
https://doi.org/10.18632/oncotarget.5645
|
| 42345-42353 |
|
| Waitandsee or radical surgery for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy: a cohort study |
|
https://doi.org/10.18632/oncotarget.6093
|
| 42354-42361 |
|
| High incidence of MYC and BCL2 abnormalities in mantle cell lymphoma although only MYC abnormality predicts poor survival |
|
https://doi.org/10.18632/oncotarget.5705
|
| 42362-42371 |
|
| Identifying the optimal criteria of radiotherapeutic parameters for patients with unresectable locally advanced hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.5713
|
| 42372-42379 |
|
| Diffusion kurtosis imaging can efficiently assess the glioma grade and cellular proliferation |
|
https://doi.org/10.18632/oncotarget.5675
|
| 42380-42393 |
Copyright © 2026 Rapamycin Press LLC dba Impact Journals
Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLCß
