VOLUME 6 (2015)
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About The Cover
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
See Duffy et al.
Table of Contents
Editorial: Chromosome
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| Extracellular vesicles in smokingrelated lung diseases |
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https://doi.org/10.18632/oncotarget.6556
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| 43144-43145 |
Priority Research Papers
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| Fra1 is a key driver of colon cancer metastasis and a Fra1 classifier predicts diseasefree survival |
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https://doi.org/10.18632/oncotarget.6454
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| 43146-43161 |
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| SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells |
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https://doi.org/10.18632/oncotarget.6351
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| 43162-43171 |
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| Epigenetic effects of RRx001: a possible unifying mechanism of anticancer activity |
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https://doi.org/10.18632/oncotarget.6526
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| 43172-43181 |
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| Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables networkbased therapeutic target discovery in neuroblastoma |
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https://doi.org/10.18632/oncotarget.6568
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| 43182-43201 |
Research Papers: Pathology
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| Combination of exercise training and erythropoietin prevents cancerinduced muscle alterations |
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https://doi.org/10.18632/oncotarget.6439
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| 43202-43215 |
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| Activation of an endothelial Notch1Jagged1 circuit induces VCAM1 expression an effect amplified by interleukin1β |
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https://doi.org/10.18632/oncotarget.6456
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| 43216-43229 |
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| The NKG2D – IL15 signaling pathway contributes to Tcell mediated pathology in inflammatory myopathies |
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https://doi.org/10.18632/oncotarget.6462
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| 43230-43243 |
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| Molecular classification of noninvasive breast lesions for personalised therapy and chemoprevention |
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https://doi.org/10.18632/oncotarget.6525
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| 43244-43254 |
Research Papers: Immunology
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| Validation of a multicolor staining to monitor <sub>phospho</sub>STAT5 levels in regulatory Tcell subsets |
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https://doi.org/10.18632/oncotarget.6486
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| 43255-43266 |
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| IL27 induces the expression of IDO and PDL1 in human cancer cells |
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https://doi.org/10.18632/oncotarget.6530
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| 43267-43280 |
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| Hepatitis B virus core antigen as a carrier for <em>Chlamydia trachomatis</em> MOMP multiepitope peptide enhances protection against genital chlamydial infection |
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https://doi.org/10.18632/oncotarget.6533
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| 43281-43292 |
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| GB virus type C E2 protein inhibits human immunodeficiency virus type 1 Gag assembly by downregulating human ADPribosylation factor 1 |
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https://doi.org/10.18632/oncotarget.6537
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| 43293-43309 |
Research Papers: Chromosome
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| Proteasome inhibition mediates p53 reactivation and anticancer activity of 6Gingerol in cervical cancer cells |
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https://doi.org/10.18632/oncotarget.6383
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| 43310-43325 |
Reviews
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| Is lineage decisionmaking restricted during tumoral reprograming of haematopoietic stem cells |
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https://doi.org/10.18632/oncotarget.6145
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| 43326-43341 |
Research Papers
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| Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis |
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https://doi.org/10.18632/oncotarget.6126
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| 43342-43362 |
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| Loss of COX5B inhibits proliferation and promotes senescence via mitochondrial dysfunction in breast cancer |
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https://doi.org/10.18632/oncotarget.6222
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| 43363-43374 |
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| Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling |
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https://doi.org/10.18632/oncotarget.6234
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| 43375-43394 |
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| IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival |
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https://doi.org/10.18632/oncotarget.6028
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| 43395-43407 |
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| CXCR3 as a molecular target in breast cancer metastasis: inhibition of tumor cell migration and promotion of host antitumor immunity |
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https://doi.org/10.18632/oncotarget.6125
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| 43408-43419 |
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| VHLdependent alterations in the secretome of renal cell carcinoma: Association with immune cell response |
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https://doi.org/10.18632/oncotarget.5560
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| 43420-43437 |
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| Collective cancer cell invasion induced by coordinated contractile stresses |
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https://doi.org/10.18632/oncotarget.5874
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| 43438-43451 |
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| Elucidating the cancerspecific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing |
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https://doi.org/10.18632/oncotarget.6171
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| 43452-43471 |
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| Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance |
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https://doi.org/10.18632/oncotarget.6179
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| 43472-43482 |
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| Phosphorylation of Nucleophosmin at Threonine 234/237 is associated with HCC metastasis |
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https://doi.org/10.18632/oncotarget.5820
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| 43483-43495 |
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| CD47retargeted oncolytic adenovirus armed with melanoma differentiationassociated gene7/interleukin24 suppresses in vivo leukemia cell growth |
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https://doi.org/10.18632/oncotarget.6292
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| 43496-43507 |
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| Antileukemic effects of the VATPase inhibitor Archazolid A |
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https://doi.org/10.18632/oncotarget.6180
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| 43508-43528 |
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| Proteoglycan expression correlates with the phenotype of malignant and nonmalignant EBVpositive Bcell lines |
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https://doi.org/10.18632/oncotarget.5984
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| 43529-43539 |
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| Molecular and functional interactions between AKT and SOX2 in breast carcinoma |
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https://doi.org/10.18632/oncotarget.6183
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| 43540-43556 |
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| Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubuleassociated protein ATIP3 |
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https://doi.org/10.18632/oncotarget.6196
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| 43557-43570 |
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| Is magnetic resonance/ultrasound fusion prostate biopsy better than systematic prostate biopsy an updated meta and trial sequential analysis |
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https://doi.org/10.18632/oncotarget.6201
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| 43571-43580 |
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| Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC |
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https://doi.org/10.18632/oncotarget.6294
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| 43581-43593 |
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| Comprehensive multiplatform biomarker analysis of 199 anal squamous cell carcinomas |
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https://doi.org/10.18632/oncotarget.6202
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| 43594-43604 |
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| Metformin attenuates gefitinibinduced exacerbation of pulmonary fibrosis by inhibition of TGFβ signaling pathway |
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https://doi.org/10.18632/oncotarget.6186
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| 43605-43619 |
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| RNAbinding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.6204
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| 43620-43634 |
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| Integrative analysis to select cancer candidate biomarkers to targeted validation |
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https://doi.org/10.18632/oncotarget.6018
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| 43635-43652 |
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| Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas |
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https://doi.org/10.18632/oncotarget.6189
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| 43653-43666 |
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| Cigarette smoking during pregnancy and preeclampsia risk: a systematic review and metaanalysis of prospective studies |
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https://doi.org/10.18632/oncotarget.6190
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| 43667-43678 |
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| 5Fluorouracilinduced RNA stress engages a TRAILDISCdependent apoptosis axis facilitated by p53 |
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https://doi.org/10.18632/oncotarget.6030
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| 43679-43697 |
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| Liposomal doxorubicin for active targeting: surface modification of the nanocarrier evaluated <em>in vitro</em> and <em>in vivo</em> — challenges and prospects |
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https://doi.org/10.18632/oncotarget.6191
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| 43698-43711 |
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| miR192 suppresses leptomeningeal dissemination of medulloblastoma by modulating cell proliferation and anchoring through the regulation of <em>DHFR</em> integrins and <em>CD47</em> |
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https://doi.org/10.18632/oncotarget.6227
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| 43712-43730 |
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| Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer |
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https://doi.org/10.18632/oncotarget.6192
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| 43731-43742 |
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| Dysregulated expression of cell surface glycoprotein CDCP1 in prostate cancer |
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https://doi.org/10.18632/oncotarget.6193
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| 43743-43758 |
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| Characterization and bioactivity of novel calcium antagonists <i>N</i>methoxybenzyl haloperidol quaternary ammonium salt |
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https://doi.org/10.18632/oncotarget.6086
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| 43759-43769 |
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| Long noncoding RNA expression profiles of hepatitis C virusrelated dysplasia and hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6087
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| 43770-43778 |
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| Enhanced therapeutic effect of Adriamycin on multidrug resistant breast cancer by the ABCG2siRNA loaded polymeric nanoparticles assisted with ultrasound |
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https://doi.org/10.18632/oncotarget.6085
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| 43779-43790 |
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| Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription |
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https://doi.org/10.18632/oncotarget.6101
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| 43791-43805 |
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| Inhibition of p300 lysine acetyltransferase activity by luteolin reduces tumor growth in head and neck squamous cell carcinoma HNSCC xenograft mouse model |
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https://doi.org/10.18632/oncotarget.6245
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| 43806-43818 |
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| Screening key microRNAs for castrationresistant prostate cancer based on miRNA/mRNA functional synergistic network |
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https://doi.org/10.18632/oncotarget.6102
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| 43819-43830 |
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| The miR24Bim pathway promotes tumor growth and angiogenesis in pancreatic carcinoma |
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https://doi.org/10.18632/oncotarget.6257
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| 43831-43842 |
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| CSIOVDB: a microarray gene expression database of epithelial ovarian cancer subtype |
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https://doi.org/10.18632/oncotarget.5983
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| 43843-43852 |
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| p21activated kinase group II small compound inhibitor GNE2861 perturbs estrogen receptor alpha signaling and restores tamoxifensensitivity in breast cancer cells |
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https://doi.org/10.18632/oncotarget.6081
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| 43853-43868 |
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| MALDIimaging reveals thymosin beta4 as an independent prognostic marker for colorectal cancer |
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https://doi.org/10.18632/oncotarget.6103
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| 43869-43880 |
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| Cerdulatinib a novel dual SYK/JAK kinase inhibitor has broad antitumor activity in both ABC and GCB types of diffuse large B cell lymphoma |
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https://doi.org/10.18632/oncotarget.6316
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| 43881-43896 |
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| The putative oncogene <i>CRNDE</i> is a negative prognostic factor in ovarian cancer patients |
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https://doi.org/10.18632/oncotarget.6016
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| 43897-43910 |
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| Glycyrrhetinic acid induces cytoprotective autophagy via the inositolrequiring enzyme 1αcJun Nterminal kinase cascade in nonsmall cell lung cancer cells |
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https://doi.org/10.18632/oncotarget.6084
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| 43911-43926 |
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| Sorafenib a multikinase inhibitor induces formation of stress granules in hepatocarcinoma cells |
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https://doi.org/10.18632/oncotarget.5980
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| 43927-43943 |
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| The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells |
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https://doi.org/10.18632/oncotarget.6267
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| 43944-43963 |
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| Invasive oral cancer stem cells display resistance to ionising radiation |
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https://doi.org/10.18632/oncotarget.6268
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| 43964-43977 |
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| PARP1 expression activity and <em>ex vivo</em> sensitivity to the PARP inhibitor talazoparib BMN 673 in chronic lymphocytic leukaemia |
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https://doi.org/10.18632/oncotarget.6287
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| 43978-43991 |
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| The bone marrow microenvironment enhances multiple myeloma progression by exosomemediated activation of myeloidderived suppressor cells |
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https://doi.org/10.18632/oncotarget.6083
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| 43992-44004 |
Clinical Research Papers
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| Neoadjuvant chemotherapy NCT plus targeted agents versus NCT alone in colorectal liver metastases patients: A systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.5875
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| 44005-44018 |
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| Propensity score matching analysis of cisplatinbased concurrent chemotherapy in low risk nasopharyngeal carcinoma in the intensitymodulated radiotherapy era |
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https://doi.org/10.18632/oncotarget.5806
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| 44019-44029 |
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| Distribution of metastatic disease in the brain in relation to the hippocampus: a retrospective singlecenter analysis of 6064 metastases in 632 patients |
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https://doi.org/10.18632/oncotarget.5828
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| 44030-44036 |
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| Serum apolipoprotein AI is a novel prognostic indicator for nonmetastatic nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.5823
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| 44037-44048 |
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| Puquitinib mesylate an inhibitor of phosphatidylinositol 3kinase p110δ for treating relapsed or refractory nonHodgkin’s lymphoma |
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https://doi.org/10.18632/oncotarget.5833
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| 44049-44056 |
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