VOLUME 6 (2015)
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ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts. See Valletta et al.
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Table of Contents
Editorial
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| Immunosuppression by hemorrhagic fevercausing viruses |
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https://doi.org/10.18632/oncotarget.6509
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| 44057-44058 |
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| KIM1/TIM1 in proximal tubular cell immune response |
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https://doi.org/10.18632/oncotarget.6623
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| 44059-44060 |
Priority Research Papers
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| ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts |
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https://doi.org/10.18632/oncotarget.6392
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| 44061-44071 |
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| SRC family kinase FYN promotes the neuroendocrine phenotype and visceral metastasis in advanced prostate cancer |
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https://doi.org/10.18632/oncotarget.6398
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| 44072-44083 |
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| Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae |
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https://doi.org/10.18632/oncotarget.6406
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| 44084-44094 |
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| MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in nonsmall cell lung carcinoma cells |
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https://doi.org/10.18632/oncotarget.6574
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| 44095-44107 |
Research Papers: Pathology
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| Ketaminemediated afferentspecific presynaptic transmission blocks in lowthreshold and sexspecific subpopulation of myelinated Ahtype baroreceptor neurons of rats |
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https://doi.org/10.18632/oncotarget.6586
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| 44108-44122 |
Research Papers: Immunology
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| Transpresentation of interleukin‑15 by IL15/IL15Rα mRNAengineered human dendritic cells boosts antitumoral natural killer cell activity |
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https://doi.org/10.18632/oncotarget.6536
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| 44123-44133 |
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| Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice |
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https://doi.org/10.18632/oncotarget.6628
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| 44134-44150 |
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| Cytokine secretion and NK cell activity in human ADAM17 deficiency |
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https://doi.org/10.18632/oncotarget.6629
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| 44151-44160 |
Research Papers: Autophagy and Cell Death
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| Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia |
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https://doi.org/10.18632/oncotarget.6592
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| 44161-44178 |
Reviews
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| Therapeutic potential of CART cellderived exosomes: a cellfree modality for targeted cancer therapy |
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https://doi.org/10.18632/oncotarget.6175
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| 44179-44190 |
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| Cancer stem cell targeted therapy: progress amid controversies |
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https://doi.org/10.18632/oncotarget.6176
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| 44191-44206 |
Research Papers
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| Growtharrestspecific 7C protein inhibits tumor metastasis via the NWASP/FAK/Factin and hnRNP U/βTrCP/βcatenin pathways in lung cancer |
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https://doi.org/10.18632/oncotarget.6229
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| 44207-44221 |
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| Foxo3amediated overexpression of microRNA622 suppresses tumor metastasis by repressing hypoxiainducible factor1α in ERKresponsive lung cancer |
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https://doi.org/10.18632/oncotarget.5826
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| 44222-44238 |
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| Phenotype and function of CXCR5+CD45RA−CD4+ T cells were altered in HBVrelated hepatocellular carcinoma and elevated serum CXCL13 predicted better prognosis |
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https://doi.org/10.18632/oncotarget.6235
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| 44239-44253 |
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| FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies |
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https://doi.org/10.18632/oncotarget.5471
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| 44254-44273 |
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| 244MPT overcomes gefitinib resistance in nonsmall cell lung cancer cells |
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https://doi.org/10.18632/oncotarget.6236
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| 44274-44288 |
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| The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the antitumor effects of cisplatin to resolve ATMdeficient nonsmall cell lung cancer in vivo |
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https://doi.org/10.18632/oncotarget.6247
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| 44289-44305 |
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| Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition |
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https://doi.org/10.18632/oncotarget.6248
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| 44306-44322 |
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| Increased expression of CX43 on stromal cells promotes leukemia apoptosis |
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https://doi.org/10.18632/oncotarget.6249
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| 44323-44331 |
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| Implication of epithelialmesenchymal transition in IGF1Rinduced resistance to EGFRTKIs in advanced nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.6293
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| 44332-44345 |
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| Infiltrating T cells promote renal cell carcinoma RCC progression via altering the estrogen receptor βDAB2IP signals |
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https://doi.org/10.18632/oncotarget.5884
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| 44346-44359 |
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| RNase L is a negative regulator of cell migration |
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https://doi.org/10.18632/oncotarget.6246
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| 44360-44372 |
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| JAM3 methylation status as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervix |
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https://doi.org/10.18632/oncotarget.6250
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| 44373-44387 |
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| Estrogen and estrogen receptor alpha promotes malignancy and osteoblastic tumorigenesis in prostate cancer |
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https://doi.org/10.18632/oncotarget.6317
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| 44388-44402 |
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| Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors |
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https://doi.org/10.18632/oncotarget.5623
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| 44403-44421 |
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| Epigenetic silencing of tumor suppressor miR3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways |
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https://doi.org/10.18632/oncotarget.6251
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| 44422-44436 |
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| Anticancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B |
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https://doi.org/10.18632/oncotarget.6295
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| 44437-44451 |
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| Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation |
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https://doi.org/10.18632/oncotarget.6090
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| 44452-44465 |
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| Upregulation of miR181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway |
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https://doi.org/10.18632/oncotarget.6298
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| 44466-44479 |
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| The Janusfaced roles of Krüppellike factor 4 in oral squamous cell carcinoma cells |
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https://doi.org/10.18632/oncotarget.6256
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| 44480-44494 |
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| Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer |
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https://doi.org/10.18632/oncotarget.6252
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| 44495-44508 |
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| Single agent BMS911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer |
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https://doi.org/10.18632/oncotarget.6332
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| 44509-44522 |
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| Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitindependent and independent proteasomal degradation pathways in breast cancer cells |
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https://doi.org/10.18632/oncotarget.5972
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| 44523-44537 |
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| Deregulation of the miR222ABCG2 regulatory module in tongue squamous cell carcinoma contributes to chemoresistance and enhanced migratory/invasive potential |
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https://doi.org/10.18632/oncotarget.6253
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| 44538-44550 |
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| Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer |
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https://doi.org/10.18632/oncotarget.6082
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| 44551-44562 |
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| Formononetin a novel FGFR2 inhibitor potently inhibits angiogenesis and tumor growth in preclinical models |
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https://doi.org/10.18632/oncotarget.6310
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| 44563-44578 |
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| Suppression of tumor angiogenesis by metformin treatment via a mechanism linked to targeting of HER2/HIF1α/VEGF secretion axis |
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https://doi.org/10.18632/oncotarget.6373
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| 44579-44592 |
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| Tamoxifen therapy benefit predictive signature coupled with prognostic signature of postoperative recurrent risk for early stage ER+ breast cancer |
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https://doi.org/10.18632/oncotarget.6260
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| 44593-44608 |
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| Tumor invasion and metastasis regulated by microRNA184 and microRNA5745p in smallcell lung cancer |
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https://doi.org/10.18632/oncotarget.6338
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| 44609-44622 |
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| EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudinlow |
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https://doi.org/10.18632/oncotarget.5977
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| 44623-44634 |
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| PPARα induces cell apoptosis by destructing Bcl2 |
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https://doi.org/10.18632/oncotarget.5988
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| 44635-44642 |
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| Effect of ceritinib LDK378 on enhancement of chemotherapeutic agents in ABCB1 and ABCG2 overexpressing cells in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.5989
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| 44643-44659 |
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| Mutant p53 induces EZH2 expression and promotes epithelial–mesenchymal transition by disrupting p68Drosha complex assembly and attenuating miR26a processing |
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https://doi.org/10.18632/oncotarget.6350
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| 44660-44674 |
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| Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.5971
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| 44675-44687 |
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| Stimulation of dendritic cells by DAMPs in ALAPDT treated SCC tumor cells |
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https://doi.org/10.18632/oncotarget.5975
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| 44688-44702 |
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| Loss of function mutations in PTPN6 promote STAT3 deregulation via JAK3 kinase in diffuse large Bcell lymphoma |
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https://doi.org/10.18632/oncotarget.6300
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| 44703-44713 |
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| A networkbased method to evaluate quality of reproducibility of differential expression in cancer genomics studies |
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https://doi.org/10.18632/oncotarget.5987
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| 44714-44727 |
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| Expression of androgen receptor splice variants in clinical breast cancers |
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https://doi.org/10.18632/oncotarget.6296
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| 44728-44744 |
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| SingleMolecule Localization Microscopy allows for the analysis of cancer metastasisspecific miRNA distribution on the nanoscale |
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https://doi.org/10.18632/oncotarget.6297
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| 44745-44757 |
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| Radiation and SN38 treatments modulate the expression of microRNAs cytokines and chemokines in colon cancer cells in a p53directed manner |
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https://doi.org/10.18632/oncotarget.5815
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| 44758-44780 |
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| A comparison of isolated circulating tumor cells and tissue biopsies using wholegenome sequencing in prostate cancer |
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https://doi.org/10.18632/oncotarget.6330
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| 44781-44793 |
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| Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiationinduced mouse thymic lymphomas |
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https://doi.org/10.18632/oncotarget.6328
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| 44794-44805 |
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| Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma |
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https://doi.org/10.18632/oncotarget.6326
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| 44806-44818 |
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| Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications |
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https://doi.org/10.18632/oncotarget.6264
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| 44819-44831 |
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| Bone marrow stromainduced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways |
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https://doi.org/10.18632/oncotarget.6265
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| 44832-44848 |
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| ACSL4 promotes prostate cancer growth invasion and hormonal resistance |
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https://doi.org/10.18632/oncotarget.6438
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| 44849-44863 |
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| Differentiation between genetic mutations of breast cancer by breath volatolomics |
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https://doi.org/10.18632/oncotarget.6269
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| 44864-44876 |
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| Genomic responses to hepatitis B virus HBV infection in primary human hepatocytes |
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https://doi.org/10.18632/oncotarget.6270
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| 44877-44891 |
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| Sensitivity of human pleural mesothelioma to oncolytic measles virus depends on defects of the type I interferon response |
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https://doi.org/10.18632/oncotarget.6285
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| 44892-44904 |
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| mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1ARas transformed cells |
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https://doi.org/10.18632/oncotarget.6457
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| 44905-44926 |
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| TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer |
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https://doi.org/10.18632/oncotarget.6743
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| 44927-44940 |
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| The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation |
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https://doi.org/10.18632/oncotarget.6759
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| 44941-44954 |
Clinical Research Papers
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| Conditional survival among patients with adrenal cortical carcinoma determined using a national populationbased surveillance epidemiology and end results registry |
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https://doi.org/10.18632/oncotarget.5831
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| 44955-44962 |
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| Clinical significance of age at diagnosis among young nonsmall cell lung cancer patients under 40 years old: a populationbased study |
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https://doi.org/10.18632/oncotarget.5524
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| 44963-44970 |
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| Phase II clinical and exploratory biomarker study of dacomitinib in recurrent and/or metastatic esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.6056
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| 44971-44984 |
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| A prospective multicenter observational study of longterm decitabine treatment in patients with myelodysplastic syndrome |
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https://doi.org/10.18632/oncotarget.6242
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| 44985-44994 |
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| Patterns of care and treatment outcomes in older patients with biliary tract cancer |
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https://doi.org/10.18632/oncotarget.5707
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| 44995-45004 |
Case Reports
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| Cerebral hemorrhage due to tuberculosis meningitis: a rare case report and literature review |
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https://doi.org/10.18632/oncotarget.6528
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| 45005-45009 |
News
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| Inhibitors of mTOR in aging and cancer |
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https://doi.org/10.18632/oncotarget.6878
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| 45010-45011 |
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