VOLUME 6 (2015)
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About The Cover
Correlation plot showing the heatmap with the Pearson’s correlation coefficient values for H4K12ac, BRD4, H3K27ac, H3K4me3, H2Bub1, GRO-seq, RNAPII and H3K27me3 on TSS and 3 kb downstream region of estrogen-upregulated genes. See Nagarajan et al.
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Table of Contents
Editorial
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| Ghrelin receptor controls obesity by fat burning |
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https://doi.org/10.18632/oncotarget.3668
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| 6470-6471 |
Reviews
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| The microRNA200 family: small molecules with novel roles in cancer development progression and therapy |
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https://doi.org/10.18632/oncotarget.3052
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| 6472-6498 |
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| CARP1 / CCAR1: A biphasic regulator of cancer cell growth and apoptosis |
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https://doi.org/10.18632/oncotarget.3376
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| 6499-6510 |
Research Papers: Gerotarget (Focus on Aging)
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| Ammonium is a key determinant on the dietary restriction of yeast chronological aging in culture medium |
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https://doi.org/10.18632/oncotarget.2989
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| 6511-6523 |
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| Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors |
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https://doi.org/10.18632/oncotarget.3002
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| 6524-6534 |
Research Papers: Pathology
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| Genomewide 5hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia |
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https://doi.org/10.18632/oncotarget.3163
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| 6535-6543 |
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| Protein kinase CK2 is widely expressed in follicular Burkitt and diffuse large Bcell lymphomas and propels malignant Bcell growth |
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https://doi.org/10.18632/oncotarget.3446
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| 6544-6552 |
Research Papers
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| Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large Bcell lymphoma |
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https://doi.org/10.18632/oncotarget.2720
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| 6553-6569 |
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| Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3262
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| 6570-6583 |
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| Pselectinmediated platelet adhesion promotes tumor growth |
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https://doi.org/10.18632/oncotarget.3164
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| 6584-6596 |
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| Triple Akt inhibition as a new therapeutic strategy in Tcell acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.3260
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| 6597-6610 |
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| Loss of p21Cip1/CDKN1A renders cancer cells susceptible to Pololike kinase 1 inhibition |
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https://doi.org/10.18632/oncotarget.2844
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| 6611-6626 |
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| Osteopontin promotes a cancer stem celllike phenotype in hepatocellular carcinoma cells via an integrin–NFκB–HIF1α pathway |
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https://doi.org/10.18632/oncotarget.3113
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| 6627-6640 |
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| The activity regulation of the mitotic centromereassociated kinesin by Pololike kinase 1 |
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https://doi.org/10.18632/oncotarget.2843
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| 6641-6655 |
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| Elevated S100A6 Calcyclin enhances tumorigenesis and suppresses CXCL14induced apoptosis in clear cell renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.3169
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| 6656-6669 |
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| Fibrillin1 induced by AuroraA but inhibited by BRCA2 promotes ovarian cancer metastasis |
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https://doi.org/10.18632/oncotarget.3118
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| 6670-6683 |
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| Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgenindependent prostate cancer cells via regulation of Skp2 p53 p21Cip1 and p27Kip1 |
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https://doi.org/10.18632/oncotarget.3246
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| 6684-6707 |
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| Disruption of BASIGIN decreases lactic acid export and sensitizes nonsmall cell lung cancer to biguanides independently of the LKB1 status |
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https://doi.org/10.18632/oncotarget.2862
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| 6708-6721 |
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| Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor UNC1666 in acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.3156
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| 6722-6736 |
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| Cblb inhibits Pgp transporter function by preventing its translocation into caveolae in multiple drugresistant gastric and breast cancers |
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https://doi.org/10.18632/oncotarget.3253
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| 6737-6748 |
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| Inhibition of nonsmall cell lung cancer NSCLC growth by a novel small molecular inhibitor of EGFR |
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https://doi.org/10.18632/oncotarget.3155
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| 6749-6761 |
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| Computational design chemical synthesis and biological evaluation of a novel ERK inhibitor BLEI001 with apoptosisinducing mechanisms in breast cancer |
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https://doi.org/10.18632/oncotarget.3105
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| 6762-6775 |
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| Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells |
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https://doi.org/10.18632/oncotarget.2882
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| 6776-6793 |
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| Snail and Slug collaborate on EMT and tumor metastasis through miR101mediated EZH2 axis in oral tongue squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.3180
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| 6794-6810 |
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| The histidinerich calcium binding protein HRC promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1 |
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https://doi.org/10.18632/oncotarget.3049
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| 6811-6824 |
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| Transcriptomewide identification and study of cancerspecific splicing events across multiple tumors |
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https://doi.org/10.18632/oncotarget.3145
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| 6825-6839 |
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| Radiationinduced PGE2 sustains human glioma cells growth and survival through EGF signaling |
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https://doi.org/10.18632/oncotarget.3160
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| 6840-6849 |
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| High expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis |
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https://doi.org/10.18632/oncotarget.3190
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| 6850-6861 |
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| Androgen receptor nonnuclear regulation of prostate cancer cell invasion mediated by Src and matriptase |
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https://doi.org/10.18632/oncotarget.3119
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| 6862-6876 |
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| H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptordependent pathway |
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https://doi.org/10.18632/oncotarget.3124
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| 6877-6886 |
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| G9a is essential for EMTmediated metastasis and maintenance of cancer stem celllike characters in head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.3159
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| 6887-6901 |
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| Depletion of eIF2·GTP·MettRNAi translation initiation complex upregulates BRCA1 expression in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.3125
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| 6902-6914 |
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| JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer |
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https://doi.org/10.18632/oncotarget.3126
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| 6915-6930 |
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| The miR4913p/mTORC2/FOXO1 regulatory loop modulates chemosensitivity in human tongue cancer |
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https://doi.org/10.18632/oncotarget.3165
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| 6931-6943 |
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| DC120 a novel AKT inhibitor preferentially suppresses nasopharyngeal carcinoma cancer stemlike cells by downregulating Sox2 |
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https://doi.org/10.18632/oncotarget.3128
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| 6944-6958 |
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| ZBRK1 a novel tumor suppressor activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer |
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https://doi.org/10.18632/oncotarget.3134
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| 6959-6976 |
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| Distinct antioncogenic effect of various microRNAs in different mouse models of liver cancer |
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https://doi.org/10.18632/oncotarget.3166
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| 6977-6988 |
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| Leukemia inhibitory factor receptor is a novel immunomarker in distinction of welldifferentiated HCC from dysplastic nodules |
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https://doi.org/10.18632/oncotarget.3136
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| 6989-6999 |
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| The PDGFD/miR106a/Twist1 pathway orchestrates epithelialmesenchymal transition in gemcitabine resistance hepatoma cells |
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https://doi.org/10.18632/oncotarget.3193
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| 7000-7010 |
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| TNKS1BP1 functions in DNA doublestrand break repair though facilitating DNAPKcs autophosphorylation dependent on PARP1 |
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https://doi.org/10.18632/oncotarget.3137
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| 7011-7022 |
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| Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.3248
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| 7023-7039 |
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| Treatmentinduced cell cycle kinetics dictate tumor response to chemotherapy |
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https://doi.org/10.18632/oncotarget.3140
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| 7040-7052 |
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| A direct plasma assay of circulating microRNA210 of hypoxia can identify early systemic metastasis recurrence in melanoma patients |
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https://doi.org/10.18632/oncotarget.3142
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| 7053-7064 |
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| A selective ATPcompetitive sphingosine kinase inhibitor demonstrates anticancer properties |
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https://doi.org/10.18632/oncotarget.3178
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| 7065-7083 |
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| Autophagybased survival prognosis in human colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.3054
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| 7084-7103 |
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| Cytokeratin 5/6 fingerprinting in HER2positive tumors identifies a poor prognosis and trastuzumabresistant BasalHER2 subtype of breast cancer |
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https://doi.org/10.18632/oncotarget.3106
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| 7104-7122 |
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| Sumoylation of HDAC2 promotes NFκBdependent gene expression |
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https://doi.org/10.18632/oncotarget.3344
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| 7123-7135 |
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| Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion |
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https://doi.org/10.18632/oncotarget.3044
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| 7136-7150 |
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| High neuropeptide Y release associates with Ewing sarcoma bone dissemination in vivo model of sitespecific metastases |
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https://doi.org/10.18632/oncotarget.3345
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| 7151-7165 |
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| Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis |
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https://doi.org/10.18632/oncotarget.3347
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| 7166-7181 |
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| Extension of the in vivo halflife of endostatin and its improved antitumor activities upon fusion to a humanized antibody against tumorassociated glycoprotein 72 in a mouse model of human colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.3121
|
| 7182-7194 |
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| Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stressmediated survival of melanoma cells |
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https://doi.org/10.18632/oncotarget.3131
|
| 7195-7208 |
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| Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis |
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https://doi.org/10.18632/oncotarget.3109
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| 7209-7220 |
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| Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective |
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https://doi.org/10.18632/oncotarget.3372
|
| 7221-7231 |
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| Multiple mechanisms of MYCN dysregulation in Wilms tumour |
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https://doi.org/10.18632/oncotarget.3377
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| 7232-7243 |
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| EGFreduced Wnt5a transcription induces epithelialmesenchymal transition via Arf6ERK signaling in gastric cancer cells |
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https://doi.org/10.18632/oncotarget.3133
|
| 7244-7261 |
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| Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs |
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https://doi.org/10.18632/oncotarget.3225
|
| 7262-7279 |
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| Bee venom inhibits growth of human cervical tumors in mice |
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https://doi.org/10.18632/oncotarget.3110
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| 7280-7292 |
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| PlexinB2 promotes invasive growth of malignant glioma |
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https://doi.org/10.18632/oncotarget.3421
|
| 7293-7304 |
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| H4K12ac is regulated by estrogen receptoralpha and is associated with BRD4 function and inducible transcription |
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https://doi.org/10.18632/oncotarget.3439
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| 7305-7317 |
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| Genetic and clinical characteristics of primary and secondary glioblastoma is associated with differential molecular subtype distribution |
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https://doi.org/10.18632/oncotarget.3440
|
| 7318-7324 |
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| microRNA29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway |
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https://doi.org/10.18632/oncotarget.2621
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| 7325-7338 |
Clinical Research Papers
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| The influence of marital status on stage at diagnosis and survival of patients with colorectal cancer |
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https://doi.org/10.18632/oncotarget.3129
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| 7339-7347 |
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| ColoLipidGene: signature of lipid metabolismrelated genes to predict prognosis in stageII colon cancer patients |
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https://doi.org/10.18632/oncotarget.3130
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| 7348-7363 |
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