Oncotarget

VOLUME 7 (2016)

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About The Cover

Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model. See Borland et al.

Table of Contents

Editorial

Lessons learned from a SIRT2selective inhibitor

https://doi.org/10.18632/oncotarget.8502
22971-22972
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Priority Research Papers

Addiction to Runx1 is partially attenuated by loss of p53 in the EµMyc lymphoma model

https://doi.org/10.18632/oncotarget.8554
22973-22987
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release

Research Papers: Gerotarget (Focus on Aging)

Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrPhAβPPswe/PS1ΔE9 mice: potential mechanism underlying cognitive impairment

https://doi.org/10.18632/oncotarget.8453
22988-23005
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis

https://doi.org/10.18632/oncotarget.8470
23006-23018
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adipose triglyceride lipase decrement affects skeletal muscle homeostasis during aging through FAsPPARαPGC1α antioxidant response

https://doi.org/10.18632/oncotarget.8552
23019-23032
Abstract  |  PDF  |  Full Text  |  How to cite

Nitrogen and carbon source balance determines longevity independently of fermentative or respiratory metabolism in the yeast Saccharomyces cerevisiae

https://doi.org/10.18632/oncotarget.8656
23033-23042
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types

https://doi.org/10.18632/oncotarget.8469
23043-23055
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circadian factors BMAL1 and RORα control HIF1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health

https://doi.org/10.18632/oncotarget.8521
23056-23071
Abstract  |  PDF  |  Full Text  |  How to cite

The pathological role of advanced glycation end productsdownregulated heat shock protein 60 in islet βcell hypertrophy and dysfunction

https://doi.org/10.18632/oncotarget.8604
23072-23087
Abstract  |  PDF  |  Full Text  |  How to cite

Effect of CTLA4 gene polymorphisms on longterm kidney allograft function in Han Chinese recipients

https://doi.org/10.18632/oncotarget.8714
23088-23095
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Role of p85α in neutrophil extra and intracellular reactive oxygen species generation

https://doi.org/10.18632/oncotarget.8500
23096-23105
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

The emerging role of FTY720 Fingolimod in cancer treatment

https://doi.org/10.18632/oncotarget.7145
23106-23127
Abstract  |  PDF  |  Full Text  |  How to cite

Does an NKTcellbased immunotherapeutic approach have a future in multiple myeloma

https://doi.org/10.18632/oncotarget.7440
23128-23140
Abstract  |  PDF  |  Full Text  |  How to cite

The altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transporters

https://doi.org/10.18632/oncotarget.8153
23141-23155
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Doublestrand break repair and colorectal cancer: gene variants within 3′ UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

https://doi.org/10.18632/oncotarget.6804
23156-23169
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

hsamiR9 controls the mobility behavior of glioblastoma cells via regulation of MAPK14 signaling elements

https://doi.org/10.18632/oncotarget.6687
23170-23181
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MRP1CD28 bispecific oligonucleotide aptamers: target costimulation to drugresistant melanoma cancer stem cells

https://doi.org/10.18632/oncotarget.8095
23182-23196
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

STARD13correlated ceRNA network inhibits EMT and metastasis of breast cancer

https://doi.org/10.18632/oncotarget.8099
23197-23211
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

E2F1induced upregulation of long noncoding RNA LINC00668 predicts a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically silencing of CKIs

https://doi.org/10.18632/oncotarget.6745
23212-23226
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab antiEGFR antibody cetuximab and the mTOR inhibitor temsirolimus

https://doi.org/10.18632/oncotarget.7594
23227-23238
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.8096
23239-23250
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Concordance of anaplastic lymphoma kinase ALK gene rearrangements between circulating tumor cells and tumor in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.8136
23251-23262
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of transcriptome data identifies a novel 5gene pancreatic adenocarcinoma classifier

https://doi.org/10.18632/oncotarget.8139
23263-23281
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+T cells within tumors

https://doi.org/10.18632/oncotarget.7818
23282-23299
Abstract  |  PDF  |  Full Text  |  How to cite

MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin

https://doi.org/10.18632/oncotarget.8188
23300-23311
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic landscape of DNA repair genes in cancer

https://doi.org/10.18632/oncotarget.8196
23312-23321
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

βcasein nanovehicles for oral delivery of chemotherapeutic drug combinations overcoming Pglycoproteinmediated multidrug resistance in human gastric cancer cells

https://doi.org/10.18632/oncotarget.8019
23322-23334
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of extracellular vesicleborne periostin as a feature of muscleinvasive bladder cancer

https://doi.org/10.18632/oncotarget.8024
23335-23345
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatitis B virus PreS2mutant large surface antigen activates storeoperated calcium entry and promotes chromosome instability

https://doi.org/10.18632/oncotarget.8109
23346-23360
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Near infrared photoimmunotherapy with an antimesothelin antibody

https://doi.org/10.18632/oncotarget.8025
23361-23369
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BAY 117085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death

https://doi.org/10.18632/oncotarget.8042
23370-23382
Abstract  |  PDF  |  Full Text  |  How to cite

Cell fate determination in cisplatin resistance and chemosensitization

https://doi.org/10.18632/oncotarget.8110
23383-23394
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NFκB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiationmediated tumor suppression

https://doi.org/10.18632/oncotarget.8246
23395-23415
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ABCG1 maintains highgrade glioma survival in vitro and in vivo

https://doi.org/10.18632/oncotarget.8030
23416-23424
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor growth suppressive effect of IL4 through p21mediated activation of STAT6 in IL4Rα overexpressed melanoma models

https://doi.org/10.18632/oncotarget.8111
23425-23438
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BCL6 modulation of acute lymphoblastic leukemia response to chemotherapy

https://doi.org/10.18632/oncotarget.8273
23439-23453
Abstract  |  PDF  |  Full Text  |  How to cite

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics

https://doi.org/10.18632/oncotarget.8032
23454-23467
Abstract  |  PDF  |  Full Text  |  How to cite

Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL induced apoptosis

https://doi.org/10.18632/oncotarget.8048
23468-23481
Abstract  |  PDF  |  Full Text  |  How to cite

Role of ADAM17 in invasion and migration of CD133expressing liver cancer stem cells after irradiation

https://doi.org/10.18632/oncotarget.8112
23482-23497
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Androgen deprivation therapy sensitizes triple negative breast cancer cells to immunemediated lysis through androgen receptor independent modulation of osteoprotegerin

https://doi.org/10.18632/oncotarget.8274
23498-23511
Abstract  |  PDF  |  Full Text  |  How to cite

Increased chemoresistance via Snail–Raf kinase inhibitor protein signaling in colorectal cancer in response to a nicotine derivative

https://doi.org/10.18632/oncotarget.8049
23512-23520
Abstract  |  PDF  |  Full Text  |  How to cite

Driver or passenger effects of augmented cMyc and Cdc20 in gliomagenesis

https://doi.org/10.18632/oncotarget.8080
23521-23529
Abstract  |  PDF  |  Full Text  |  How to cite

GP73 Nglycosylation at Asn144 reduces hepatocellular carcinoma cell motility and invasiveness

https://doi.org/10.18632/oncotarget.8120
23530-23541
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effect of sorafenib on cisplatinbased chemoradiation in head and neck cancer cells

https://doi.org/10.18632/oncotarget.8275
23542-23551
Abstract  |  PDF  |  Full Text  |  How to cite

Krüppellike factor 8 activates the transcription of CXC cytokine receptor type 4 to promote breast cancer cell invasion transendothelial migration and metastasis

https://doi.org/10.18632/oncotarget.8083
23552-23568
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel circulating peptide biomarkers for esophageal squamous cell carcinoma revealed by a magnetic beadbased MALDITOFMS assay

https://doi.org/10.18632/oncotarget.8123
23569-23580
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Progression of benign prostatic hyperplasia is associated with proinflammatory mediators and chronic activation of prostateinfiltrating lymphocytes

https://doi.org/10.18632/oncotarget.8051
23581-23593
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HER2siRNA delivered by EGFRspecific single chain antibody inhibits NSCLC cell proliferation and tumor growth

https://doi.org/10.18632/oncotarget.8053
23594-23607
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3PI3KNFκB compensatory survival signaling

https://doi.org/10.18632/oncotarget.8281
23608-23632
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance antitumor efficacy in uveal melanoma

https://doi.org/10.18632/oncotarget.8054
23633-23646
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between serum CA724 and HER2 overexpression among stage II–III resectable gastric cancer patients: an observational study

https://doi.org/10.18632/oncotarget.8145
23647-23657
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tolllike receptors 1 2 4 and 6 in esophageal epithelium Barrett’s esophagus dysplasia and adenocarcinoma

https://doi.org/10.18632/oncotarget.8151
23658-23667
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA16 sensitizes breast cancer cells to paclitaxel through suppression of IKBKB expression

https://doi.org/10.18632/oncotarget.8056
23668-23683
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Escin Ia suppresses the metastasis of triplenegative breast cancer by inhibiting epithelialmesenchymal transition via downregulating LOXL2 expression

https://doi.org/10.18632/oncotarget.8152
23684-23699
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SNPSNP interactions of three new primiRNAs with the target gene PGC and multidimensional analysis of H pylori in the gastric cancer/atrophic gastritis risk in a Chinese population

https://doi.org/10.18632/oncotarget.8057
23700-23714
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TKI sensitivity patterns of novel kinasedomain mutations suggest therapeutic opportunities for patients with resistant ALK+ tumors

https://doi.org/10.18632/oncotarget.8173
23715-23729
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dormancy activation mechanism of tracheal stem cells

https://doi.org/10.18632/oncotarget.8179
23730-23739
Abstract  |  PDF  |  Full Text  |  How to cite

The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF1αdependent and independent manners

https://doi.org/10.18632/oncotarget.8060
23740-23756
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition

https://doi.org/10.18632/oncotarget.8121
23757-23771
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Virtual screeningdriven repositioning of etoposide as CD44 antagonist in breast cancer cells

https://doi.org/10.18632/oncotarget.8180
23772-23784
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of TRPV2 and BKCa channels by the LL37 enantiomers stimulates calcium entry and migration of cancer cells

https://doi.org/10.18632/oncotarget.8122
23785-23800
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxiaregulated gene expression explains differences between melanoma cell linederived xenografts and patientderived xenografts

https://doi.org/10.18632/oncotarget.8181
23801-23811
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The NEDD8activating enzyme inhibitor MLN4924 induces G2 arrest and apoptosis in Tcell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.8068
23812-23824
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations

https://doi.org/10.18632/oncotarget.8183
23825-23836
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PIM1 destabilization activates a p53dependent response to ribosomal stress in cancer cells

https://doi.org/10.18632/oncotarget.8070
23837-23849
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Rnf25/AO7 positively regulates wnt signaling via disrupting Nkd1Axin inhibitory complex independent of its ubiquitin ligase activity

https://doi.org/10.18632/oncotarget.8126
23850-23859
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IMB6G a novel Nsubstituted sophoridinic acid derivative induces endoplasmic reticulum stressmediated apoptosis via activation of IRE1α and PERK signaling

https://doi.org/10.18632/oncotarget.8184
23860-23873
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinicopathologic characteristics of EGFR KRAS and ALK alterations in 6595 lung cancers

https://doi.org/10.18632/oncotarget.8074
23874-23884
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inactivation of RASA1 promotes melanoma tumorigenesis via RRas activation

https://doi.org/10.18632/oncotarget.8127
23885-23896
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrated analysis of long noncoding RNAs in human colorectal cancer

https://doi.org/10.18632/oncotarget.8192
23897-23908
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of CC chemokine receptor 2 associates with poor overall survival in gastric cancer patients after surgical resection

https://doi.org/10.18632/oncotarget.8069
23909-23918
Abstract  |  PDF  |  Full Text  |  How to cite

Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth

https://doi.org/10.18632/oncotarget.8081
23919-23932
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Triptolide has anticancer and chemosensitization effects by downregulating Akt activation through the MDM2/REST pathway in human breast cancer

https://doi.org/10.18632/oncotarget.8207
23933-23946
Abstract  |  PDF  |  Full Text  |  How to cite

Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis

https://doi.org/10.18632/oncotarget.8114
23947-23960
Abstract  |  PDF  |  Full Text  |  How to cite

Plasminogen activator inhibitor1 enhances radioresistance and aggressiveness of nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.8208
23961-23974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion

https://doi.org/10.18632/oncotarget.8073
23975-23987
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Armored long noncoding RNA MEG3 targeting EGFR based on recombinant MS2 bacteriophage viruslike particles against hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8115
23988-24004
Abstract  |  PDF  |  Full Text  |  How to cite

Cterminal truncated hepatitis B virus X protein promotes hepatocellular carcinogenesis through induction of cancer and stem celllike properties

https://doi.org/10.18632/oncotarget.8209
24005-24017
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Transmembrane adaptor protein PAG1 is a novel tumor suppressor in neuroblastoma

https://doi.org/10.18632/oncotarget.8116
24018-24026
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Discovery and characterization of Isofistularin3 a marine brominated alkaloid as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells

https://doi.org/10.18632/oncotarget.8210
24027-24049
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

cRGD inhibits vasculogenic mimicry formation by downregulating uPA expression and reducing EMT in ovarian cancer

https://doi.org/10.18632/oncotarget.8079
24050-24062
Abstract  |  PDF  |  Full Text  |  How to cite

An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2

https://doi.org/10.18632/oncotarget.8211
24063-24075
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/βcatenin signaling in breast cancer

https://doi.org/10.18632/oncotarget.8119
24076-24087
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prospective phase II trial of pazopanib plus CapeOX capecitabine and oxaliplatin in previously untreated patients with advanced gastric cancer

https://doi.org/10.18632/oncotarget.8175
24088-24096
Abstract  |  PDF  |  Full Text  |  How to cite

An individualized prognostic signature and multi‑omics distinction for early stage hepatocellular carcinoma patients with surgical resection

https://doi.org/10.18632/oncotarget.8212
24097-24110
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor necrosis factor receptor 2signaling in CD133expressing cells in renal clear cell carcinoma

https://doi.org/10.18632/oncotarget.8125
24111-24124
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1

https://doi.org/10.18632/oncotarget.8214
24125-24140
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenylethanolamine Nmethyltransferase downregulation is associated with malignant pheochromocytoma/paraganglioma

https://doi.org/10.18632/oncotarget.8234
24141-24153
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by upregulating p38 MAP kinase

https://doi.org/10.18632/oncotarget.8131
24154-24171
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic profiling of lung adenocarcinoma patients reveals therapeutic targets and confers clinical benefit when standard molecular testing is negative

https://doi.org/10.18632/oncotarget.8138
24172-24178
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hedgehog pathway maintains cell survival under stress conditions and drives drug resistance in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.8253
24179-24193
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis

https://doi.org/10.18632/oncotarget.8254
24194-24207
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Survival analysis of patients with advancedstage nasopharyngeal carcinoma according to the EpsteinBarr virus status

https://doi.org/10.18632/oncotarget.8144
24208-24216
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Predictive value of angiogenesisrelated gene profiling in patients with HER2negative metastatic breast cancer treated with bevacizumab and weekly paclitaxel

https://doi.org/10.18632/oncotarget.8128
24217-24227
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC

https://doi.org/10.18632/oncotarget.8286
24228-24241
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional role of eukaryotic translation initiation factor 4 gamma 1 EIF4G1 in NSCLC

https://doi.org/10.18632/oncotarget.8168
24242-24251
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use

https://doi.org/10.18632/oncotarget.8132
24252-24268
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PDL1 is an independent prognostic predictor in gastric cancer of Western patients

https://doi.org/10.18632/oncotarget.8169
24269-24283
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The retinoblastoma protein regulates hypoxiainducible genetic programs tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells

https://doi.org/10.18632/oncotarget.8301
24284-24302
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Multilevel induction of apoptosis by microtubuleinterfering inhibitors 4βSaromatic heterocyclic podophyllum derivatives causing multifold mitochondrial depolarization and PKA signaling pathways in HeLa cells

https://doi.org/10.18632/oncotarget.8147
24303-24313
Abstract  |  PDF  |  Full Text  |  How to cite

Oncogenic protein SALL4 and ZNF217 as prognostic indicators in solid cancers: a meta‑analysis of individual studies

https://doi.org/10.18632/oncotarget.8237
24314-24325
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic and epigenomic analysis of highrisk prostate cancer reveals changes in hydroxymethylation and TET1

https://doi.org/10.18632/oncotarget.8220
24326-24338
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53CRM1 interaction and changing the cellular compartmentalization of p53 protein

https://doi.org/10.18632/oncotarget.8248
24339-24347
Abstract  |  PDF  |  Full Text  |  How to cite

Eukaryotic translation initiation factor 5A2 regulates the migration and invasion of hepatocellular carcinoma cells via pathways involving reactive oxygen species

https://doi.org/10.18632/oncotarget.8324
24348-24360
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EGFR mediates hyperlipidemiainduced renal injury via regulating inflammation and oxidative stress: the detrimental role and mechanism of EGFR activation

https://doi.org/10.18632/oncotarget.8222
24361-24373
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ANO1 protein as a potential biomarker for esophageal cancer prognosis and precancerous lesion development prediction

https://doi.org/10.18632/oncotarget.8223
24374-24382
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Twist1related miR26b5p suppresses epithelialmesenchymal transition migration and invasion by targeting SMAD1 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8328
24383-24401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prevention of cisplatinbased chemotherapyinduced delayed nausea and vomiting using triple antiemetic regimens: a mixed treatment comparison

https://doi.org/10.18632/oncotarget.8255
24402-24414
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional characterization and anticancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor

https://doi.org/10.18632/oncotarget.8329
24415-24428
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nimotuzumab combined with concurrent chemoradiotherapy in locally advanced nasopharyngeal carcinoma: a retrospective analysis

https://doi.org/10.18632/oncotarget.8225
24429-24435
Abstract  |  PDF  |  Full Text  |  How to cite

BM microenvironmental protection of CML cells from imatinib through Stat5/NFκB signaling and reversal by Wogonin

https://doi.org/10.18632/oncotarget.8332
24436-24454
Abstract  |  PDF  |  Full Text  |  How to cite

Neuropathy correlated with imbalanced Foxp3/IL17 in bone marrow microenvironment of patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.8227
24455-24465
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA421 regulated by HIF1α promotes metastasis inhibits apoptosis and induces cisplatin resistance by targeting Ecadherin and caspase3 in gastric cancer

https://doi.org/10.18632/oncotarget.8228
24466-24482
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phosphorylation of TOPK at Y74 Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon

https://doi.org/10.18632/oncotarget.8231
24483-24494
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5

https://doi.org/10.18632/oncotarget.8336
24495-24509
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR206 regulates cisplatin resistance and EMT in human lung adenocarcinoma cells partly by targeting MET

https://doi.org/10.18632/oncotarget.8229
24510-24526
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Granulocyte macrophage colonystimulating factor predicts postoperative recurrence of clearcell renal cell carcinoma

https://doi.org/10.18632/oncotarget.8235
24527-24536
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR206 suppresses epithelial mesenchymal transition by targeting TGFβ signaling in estrogen receptor positive breast cancer cells

https://doi.org/10.18632/oncotarget.8233
24537-24548
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic implications of PIK3CA amplification in curatively resected liposarcoma

https://doi.org/10.18632/oncotarget.8240
24549-24558
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR31 is distinctively overexpressed in primary male extramammary Paget's disease

https://doi.org/10.18632/oncotarget.8230
24559-24563
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chronic inflammationassociated genomic instability paves the way for human esophageal carcinogenesis

https://doi.org/10.18632/oncotarget.8356
24564-24571
Abstract  |  PDF  |  Full Text  |  How to cite

Fasassociated protein with death domain FADD regulates autophagy through promoting the expression of Ras homolog enriched in brain Rheb in human breast adenocarcinoma cells

https://doi.org/10.18632/oncotarget.8249
24572-24584
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exosomes derived from gefitinibtreated EGFRmutant lung cancer cells alter cisplatin sensitivity via upregulating autophagy

https://doi.org/10.18632/oncotarget.8358
24585-24595
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of mutational and clinicopathologic characteristics of lung adenocarcinoma with clear cell component

https://doi.org/10.18632/oncotarget.8258
24596-24603
Abstract  |  PDF  |  Full Text  |  How to cite

Multifunctional targeting vinorelbine plus tetrandrine liposomes for treating brain glioma along with eliminating glioma stem cells

https://doi.org/10.18632/oncotarget.8360
24604-24622
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proper hepatic pedicle clamping during hepatectomy is associated with improved postoperative longterm prognosis in patients with AJCC stage IIIB hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8331
24623-24632
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cefradine blocks solarultraviolet induced skin inflammation through direct inhibition of TLAK celloriginated protein kinase

https://doi.org/10.18632/oncotarget.8260
24633-24645
Abstract  |  PDF  |  Full Text  |  How to cite

KIF23 is an independent prognostic biomarker in glioma transcriptionally regulated by TCF4

https://doi.org/10.18632/oncotarget.8261
24646-24655
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prevalence characteristics of highrisk human papillomaviruses in women living in Shanghai with cervical precancerous lesions and cancer

https://doi.org/10.18632/oncotarget.8262
24656-24663
Abstract  |  PDF  |  Full Text  |  How to cite

Altered neutrophil immunophenotypes in childhood B‑cell precursor acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.8369
24664-24676
Abstract  |  PDF  |  Full Text  |  How to cite

Epithelialtomesenchymal transition leads to loss of EpCAM and different physical properties in circulating tumor cells from metastatic breast cancer

https://doi.org/10.18632/oncotarget.8250
24677-24687
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of epithelialmesenchymal transitionrelated genes increases with copy number in multiple cancer types

https://doi.org/10.18632/oncotarget.8371
24688-24699
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Progerin impairs chromosome maintenance by depleting CENPF from metaphase kinetochores in HutchinsonGilford progeria fibroblasts

https://doi.org/10.18632/oncotarget.8267
24700-24718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Netrin1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer

https://doi.org/10.18632/oncotarget.8348
24719-24733
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The microRNA124iGluR2/3 pathway regulates glucagon release from alpha cells

https://doi.org/10.18632/oncotarget.8270
24734-24743
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive value of EGFR overexpression and gene amplification on icotinib efficacy in patients with advanced esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8271
24744-24751
Abstract  |  PDF  |  Full Text  |  How to cite

Combination of an antiEGFRvIII antibody CH12 with Rapamycin synergistically inhibits the growth of EGFRvIII+PTEN–glioblastoma in vivo

https://doi.org/10.18632/oncotarget.8407
24752-24765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A comprehensive repertoire of tRNAderived fragments in prostate cancer

https://doi.org/10.18632/oncotarget.8293
24766-24777
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNA promoter hypermethylation in nipple fluid: a potential tool for early breast cancer detection

https://doi.org/10.18632/oncotarget.8352
24778-24791
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Monocyte chemotactic protein1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a highfat diet

https://doi.org/10.18632/oncotarget.8364
24792-24799
Abstract  |  PDF  |  Full Text  |  How to cite

Promoter methylation of RNF180 is associated with Hpylori infection and serves as a marker for gastric cancer and atrophic gastritis

https://doi.org/10.18632/oncotarget.8523
24800-24809
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The tumorinhibitory effectiveness of a novel antiTrop2 Fab conjugate in pancreatic cancer

https://doi.org/10.18632/oncotarget.8529
24810-24823
Abstract  |  PDF  |  Full Text  |  How to cite

New insights into the prognostic value of Ki67 labeling index in patients with triplenegative breast cancer

https://doi.org/10.18632/oncotarget.8531
24824-24831
Abstract  |  PDF  |  Full Text  |  How to cite

G protein γ subunit 7 induces autophagy and inhibits cell division

https://doi.org/10.18632/oncotarget.8559
24832-24847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

The role of postmastectomy radiotherapy in clinically nodepositive stage IIIII breast cancer patients with pathological negative nodes after neoadjuvant chemotherapy: an analysis from the NCDB

https://doi.org/10.18632/oncotarget.6664
24848-24859
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Use of dedicated gene panel sequencing using next generation sequencing to improve the personalized care of lung cancer

https://doi.org/10.18632/oncotarget.8391
24860-24870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sitagliptin use and thyroid cancer risk in patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.8399
24871-24879
Abstract  |  PDF  |  Full Text  |  How to cite

Marital status independently predicts pancreatic cancer survival in patients treated with surgical resection: an analysis of the SEER database

https://doi.org/10.18632/oncotarget.8467
24880-24887
Abstract  |  PDF  |  Full Text  |  How to cite

Therapy to target renal cell carcinoma using 131Ilabeled B7H3 monoclonal antibody

https://doi.org/10.18632/oncotarget.8550
24888-24898
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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