VOLUME 7 (2016)
Table of Contents
Priority Research Papers
|
| Intrinsic resistance to PIM kinase inhibition in AML through p38αmediated feedback activation of mTOR signaling |
|
https://doi.org/10.18632/oncotarget.9822
|
| 37407-37419 |
Research Papers: Gerotarget (Focus on Aging)
|
| MiR23adepressed autophagy is a participant in PUVA and UVBinduced premature senescence |
|
https://doi.org/10.18632/oncotarget.9357
|
| 37420-37435 |
|
| The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons |
|
https://doi.org/10.18632/oncotarget.9545
|
| 37436-37455 |
Research Papers: Pathology
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| Caspase8 inhibition represses initial human monocyte activation in septic shock model |
|
https://doi.org/10.18632/oncotarget.9648
|
| 37456-37470 |
|
| Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation |
|
https://doi.org/10.18632/oncotarget.9650
|
| 37471-37486 |
Research Papers: Immunology
|
| HCVrelated liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2 |
|
https://doi.org/10.18632/oncotarget.9303
|
| 37487-37497 |
|
| TIM4 is differentially expressed in the distinct subsets of dendritic cells in skin and skindraining lymph nodes and controls skin Langerhans cell homeostasis |
|
https://doi.org/10.18632/oncotarget.9546
|
| 37498-37512 |
Research Papers
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| Salmonella inhibits tumor angiogenesis by downregulation of vascular endothelial growth factor |
|
https://doi.org/10.18632/oncotarget.7038
|
| 37513-37523 |
|
| Downregulation of miR101 contributes to epithelialmesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2 |
|
https://doi.org/10.18632/oncotarget.6852
|
| 37524-37535 |
|
| cSrc/Cav1dependent activation of the EGFR by Dsg2 |
|
https://doi.org/10.18632/oncotarget.7675
|
| 37536-37555 |
|
| Nomogram based on systemic inflammatory response markers predicting the survival of patients with resectable gastric cancer after D2 gastrectomy |
|
https://doi.org/10.18632/oncotarget.8788
|
| 37556-37565 |
|
| NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing |
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https://doi.org/10.18632/oncotarget.8885
|
| 37566-37580 |
|
| The epithelialmesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients |
|
https://doi.org/10.18632/oncotarget.9036
|
| 37581-37588 |
|
| Dosimetric impact of intermediate dose calculation for optimization convergence error |
|
https://doi.org/10.18632/oncotarget.7743
|
| 37589-37598 |
|
| Angiogenesis genotyping in the selection of firstline treatment with either sunitinib or pazopanib for advanced renal cell carcinoma |
|
https://doi.org/10.18632/oncotarget.9229
|
| 37599-37607 |
|
| Immortalization capacity of HPV types is inversely related to chromosomal instability |
|
https://doi.org/10.18632/oncotarget.8058
|
| 37608-37621 |
|
| A novel TRPV4specific agonist inhibits monocyte adhesion and atherosclerosis |
|
https://doi.org/10.18632/oncotarget.9376
|
| 37622-37635 |
|
| Genetic landscape of T and NKcell posttransplant lymphoproliferative disorders |
|
https://doi.org/10.18632/oncotarget.9400
|
| 37636-37648 |
|
| MARCKS contributes to stromal cancerassociated fibroblast activation and facilitates ovarian cancer metastasis |
|
https://doi.org/10.18632/oncotarget.8726
|
| 37649-37663 |
|
| Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2 Src and HIF1α signaling nexus |
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https://doi.org/10.18632/oncotarget.9224
|
| 37664-37679 |
|
| Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2positive breast cancer patients who have progressed on trastuzumabbased regimen |
|
https://doi.org/10.18632/oncotarget.8974
|
| 37680-37692 |
|
| MicroRNAmediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.9264
|
| 37693-37713 |
|
| Blockade of MCP1/CCR4 signalinginduced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.9265
|
| 37714-37727 |
|
| Nuclear delivery of recombinant OCT4 by chitosan nanoparticles for transgenefree generation of proteininduced pluripotent stem cells |
|
https://doi.org/10.18632/oncotarget.9276
|
| 37728-37739 |
|
| WDR5 high expression and its effect on tumorigenesis in leukemia |
|
https://doi.org/10.18632/oncotarget.9312
|
| 37740-37754 |
|
| Abdominal scar characteristics as a predictor of cervical stenosis after abdominal radical trachelectomy |
|
https://doi.org/10.18632/oncotarget.9318
|
| 37755-37761 |
|
| The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigenspecific T cells |
|
https://doi.org/10.18632/oncotarget.9326
|
| 37762-37772 |
|
| Crosstalk between the HIF1 and Tolllike receptor/nuclear factorκB pathways in the oral squamous cell carcinoma microenvironment |
|
https://doi.org/10.18632/oncotarget.9329
|
| 37773-37789 |
|
| Demonstration of a WNT5AIL6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion |
|
https://doi.org/10.18632/oncotarget.9332
|
| 37790-37802 |
|
| dbCPG: A web resource for cancer predisposition genes |
|
https://doi.org/10.18632/oncotarget.9334
|
| 37803-37811 |
|
| LncRNARMRP promotes carcinogenesis by acting as a miR206 sponge and is used as a novel biomarker for gastric cancer |
|
https://doi.org/10.18632/oncotarget.9336
|
| 37812-37824 |
|
| Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility |
|
https://doi.org/10.18632/oncotarget.9339
|
| 37825-37838 |
|
| Circulating AR copy number and outcome to enzalutamide in docetaxeltreated metastatic castrationresistant prostate cancer |
|
https://doi.org/10.18632/oncotarget.9341
|
| 37839-37845 |
|
| Geneexpression analysis of gleason grade 3 tumor glands embedded in low and highrisk prostate cancer |
|
https://doi.org/10.18632/oncotarget.9344
|
| 37846-37856 |
|
| Long noncoding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR206 |
|
https://doi.org/10.18632/oncotarget.9347
|
| 37857-37867 |
|
| Long noncoding RNA DANCR promotes invasion of prostate cancer through epigenetically silencing expression of TIMP2/3 |
|
https://doi.org/10.18632/oncotarget.9350
|
| 37868-37881 |
|
| DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire |
|
https://doi.org/10.18632/oncotarget.9352
|
| 37882-37892 |
|
| Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1 |
|
https://doi.org/10.18632/oncotarget.9247
|
| 37893-37905 |
|
| Identification of polycystic ovary syndrome potential drug targets based on pathobiological similarity in the proteinprotein interaction network |
|
https://doi.org/10.18632/oncotarget.9353
|
| 37906-37919 |
|
| Quantitative assessment of the association between APC promoter methylation and breast cancer |
|
https://doi.org/10.18632/oncotarget.9354
|
| 37920-37930 |
|
| Granulocytic myeloidderived suppressor cells promote angiogenesis in the context of multiple myeloma |
|
https://doi.org/10.18632/oncotarget.9270
|
| 37931-37943 |
|
| Piwiinteracting RNAs and PIWI genes as novel prognostic markers for breast cancer |
|
https://doi.org/10.18632/oncotarget.9272
|
| 37944-37956 |
|
| Long noncoding RNA metastasis associated in lung adenocarcinoma transcript 1 MALAT1 interacts with estrogen receptor and predicted poor survival in breast cancer |
|
https://doi.org/10.18632/oncotarget.9364
|
| 37957-37965 |
|
| HDAC5 a potential therapeutic target and prognostic biomarker promotes proliferation invasion and migration in human breast cancer |
|
https://doi.org/10.18632/oncotarget.9274
|
| 37966-37978 |
|
| Bidirectional roles of IRF1 on autophagy diminish its prognostic value as compared with Ki67 in liver transplantation for hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.9365
|
| 37979-37992 |
|
| The tumor suppressive miR200b subfamily is an ERG target gene in human prostate tumors |
|
https://doi.org/10.18632/oncotarget.9366
|
| 37993-38003 |
|
| GFOD1 and peejar are promising markers for clearcell renal cell carcinoma disease progression |
|
https://doi.org/10.18632/oncotarget.9379
|
| 38004-38009 |
|
| CAPE suppresses migration and invasion of prostate cancer cells via activation of noncanonical Wnt signaling |
|
https://doi.org/10.18632/oncotarget.9380
|
| 38010-38024 |
|
| Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells |
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https://doi.org/10.18632/oncotarget.9443
|
| 38025-38035 |
|
| Notch1 pathwaymediated microRNA1515p promotes gastric cancer progression |
|
https://doi.org/10.18632/oncotarget.9342
|
| 38036-38051 |
|
| HEY2 a target of miR137 indicates poor outcomes and promotes cell proliferation and migration in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.9343
|
| 38052-38063 |
|
| A novel p70 S6 kinasemicroRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression |
|
https://doi.org/10.18632/oncotarget.9345
|
| 38064-38077 |
|
| Derivatives of 6cinnamamidoquinoline4carboxamide impair lysosome function and induce apoptosis |
|
https://doi.org/10.18632/oncotarget.9348
|
| 38078-38090 |
|
| Simm530 a novel and highly selective cMet inhibitor blocks cMetstimulated signaling and neoplastic activities |
|
https://doi.org/10.18632/oncotarget.9349
|
| 38091-38104 |
|
| Phage display library selection of a hypoxiabinding scFv antibody for liver cancer metabolic marker discovery |
|
https://doi.org/10.18632/oncotarget.9460
|
| 38105-38121 |
|
| Prognostic impact of history of follicular lymphoma induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma |
|
https://doi.org/10.18632/oncotarget.9473
|
| 38122-38132 |
|
| S100A7 induction is repressed by YAP via the Hippo pathway in A431 cells |
|
https://doi.org/10.18632/oncotarget.9477
|
| 38133-38142 |
|
| Downregulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers |
|
https://doi.org/10.18632/oncotarget.9411
|
| 38143-38153 |
|
| Downregulation of ABCG2 and ABCB4 transporters in the placenta of rats exposed to cadmium |
|
https://doi.org/10.18632/oncotarget.9415
|
| 38154-38163 |
|
| Quantitation of TGFβ proteins in mouse tissues shows reciprocal changes in TGFβ1 and TGFβ3 in normal vs neoplastic mammary epithelium |
|
https://doi.org/10.18632/oncotarget.9416
|
| 38164-38179 |
|
| Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations |
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https://doi.org/10.18632/oncotarget.9500
|
| 38180-38190 |
|
| Dual PI3K and mTORinhibitor PI103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVPAUY922 in tumor cells: The role of drugirradiation schedule |
|
https://doi.org/10.18632/oncotarget.9501
|
| 38191-38209 |
|
| Efficacy of CD46targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers |
|
https://doi.org/10.18632/oncotarget.9427
|
| 38210-38223 |
|
| Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene |
|
https://doi.org/10.18632/oncotarget.9502
|
| 38224-38234 |
|
| Accumulation of RNAdependent protein kinase PKR in the nuclei of lung cancer cells mediates radiation resistance |
|
https://doi.org/10.18632/oncotarget.9428
|
| 38235-38242 |
|
| Drug conjugated nanoparticles activated by cancer cell specific mRNA |
|
https://doi.org/10.18632/oncotarget.9430
|
| 38243-38256 |
|
| Aptamerguided DNA tetrahedron as a novel targeted drug delivery system for MUC1expressing breast cancer cells in vitro |
|
https://doi.org/10.18632/oncotarget.9431
|
| 38257-38269 |
|
| The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation |
|
https://doi.org/10.18632/oncotarget.9505
|
| 38270-38281 |
|
| Cooption of preexisting vascular beds in adipose tissue controls tumor growth rates and angiogenesis |
|
https://doi.org/10.18632/oncotarget.9436
|
| 38282-38291 |
|
| Sorafenib inhibits macrophagemediated epithelialmesenchymal transition in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.9438
|
| 38292-38305 |
|
| Cabazitaxel operates antimetastatic and cytotoxic via apoptosis induction and stalls brain tumor angiogenesis |
|
https://doi.org/10.18632/oncotarget.9439
|
| 38306-38318 |
|
| BET bromodomainmediated interaction between ERG and BRD4 promotes prostate cancer cell invasion |
|
https://doi.org/10.18632/oncotarget.9513
|
| 38319-38332 |
|
| Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential |
|
https://doi.org/10.18632/oncotarget.9518
|
| 38333-38346 |
|
| ChREBP promotes the differentiation of leukemiainitiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways |
|
https://doi.org/10.18632/oncotarget.9520
|
| 38347-38358 |
|
| Utility of patientderived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients |
|
https://doi.org/10.18632/oncotarget.9521
|
| 38359-38366 |
|
| Targeting DNA repair with aphidicolin sensitizes primary chronic lymphocytic leukemia cells to purine analogs |
|
https://doi.org/10.18632/oncotarget.9525
|
| 38367-38379 |
|
| Radiosensitization by the investigational NEDD8activating enzyme inhibitor MLN4924 pevonedistat in hormoneresistant prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.9526
|
| 38380-38391 |
|
| Superior mediastinal mature cystic teratoma with gastrointestinal adenocarcinoma transformation: Report of a case |
|
https://doi.org/10.18632/oncotarget.9532
|
| 38392-38397 |
|
| H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction |
|
https://doi.org/10.18632/oncotarget.9534
|
| 38398-38407 |
|
| Expression of transmembrane protein 26 TMEM26 in breast cancer and its association with drug response |
|
https://doi.org/10.18632/oncotarget.9493
|
| 38408-38426 |
|
| Loss of GFAT1 promotes epithelialtomesenchymal transition and predicts unfavorable prognosis in gastric cancer |
|
https://doi.org/10.18632/oncotarget.9538
|
| 38427-38439 |
|
| Validation of a multiomics strategy for prioritizing personalized candidate driver genes |
|
https://doi.org/10.18632/oncotarget.9540
|
| 38440-38450 |
|
| Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented crosspresentation |
|
https://doi.org/10.18632/oncotarget.9498
|
| 38451-38466 |
|
| Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib |
|
https://doi.org/10.18632/oncotarget.9542
|
| 38467-38486 |
|
| Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weightedgene coexpression analysis |
|
https://doi.org/10.18632/oncotarget.9555
|
| 38487-38499 |
|
| Enhanced antitumor activity and cytotoxic effect on cancer stem cell population of metforminbutyrate compared with metformin HCl in breast cancer |
|
https://doi.org/10.18632/oncotarget.9522
|
| 38500-38512 |
|
| Dynamic contrastenhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis |
|
https://doi.org/10.18632/oncotarget.9567
|
| 38513-38522 |
|
| High throughput chemical library screening identifies a novel p110δ inhibitor that potentiates the antimyeloma effect of bortezomib |
|
https://doi.org/10.18632/oncotarget.9568
|
| 38523-38538 |
|
| Diabetes mellitus stimulates pancreatic cancer growth and epithelialmesenchymal transitionmediated metastasis via a p38 MAPK pathway |
|
https://doi.org/10.18632/oncotarget.9533
|
| 38539-38550 |
|
| Alterations of androgen receptorregulated enhancer RNAs eRNAs contribute to enzalutamide resistance in castrationresistant prostate cancer |
|
https://doi.org/10.18632/oncotarget.9535
|
| 38551-38565 |
|
| Basic fibroblast growth factor promotes VEGFCdependent lymphangiogenesis via inhibition of miR381 in human chondrosarcoma cells |
|
https://doi.org/10.18632/oncotarget.9570
|
| 38566-38578 |
|
| Association of peripheral leukocyte telomere length and its variation with pancreatic cancer and colorectal cancer risk in Chinese population |
|
https://doi.org/10.18632/oncotarget.9536
|
| 38579-38585 |
|
| Targeting Notch1 positive acute leukemia cells by novel fucosebound liposomes carrying daunorubicin |
|
https://doi.org/10.18632/oncotarget.9558
|
| 38586-38597 |
|
| Selective antitumor activity of roscovitine in head and neck cancer |
|
https://doi.org/10.18632/oncotarget.9560
|
| 38598-38611 |
|
| MicroRNA320a inhibits breast cancer metastasis by targeting metadherin |
|
https://doi.org/10.18632/oncotarget.9572
|
| 38612-38625 |
|
| JMJD2B is required for Helicobacter pyloriinduced gastric carcinogenesis via regulating COX2 expression |
|
https://doi.org/10.18632/oncotarget.9573
|
| 38626-38637 |
|
| Cellular prion protein controls stem celllike properties of human glioblastoma tumorinitiating cells |
|
https://doi.org/10.18632/oncotarget.9575
|
| 38638-38657 |
|
| Identification of associations between small molecule drugs and miRNAs based on functional similarity |
|
https://doi.org/10.18632/oncotarget.9577
|
| 38658-38669 |
|
| Functional/activity network FAN analysis of genephenotype connectivity liaised by grape polyphenol resveratrol |
|
https://doi.org/10.18632/oncotarget.9578
|
| 38670-38680 |
|
| EAAT3 promotes amino acid transport and proliferation of porcine intestinal epithelial cells |
|
https://doi.org/10.18632/oncotarget.9583
|
| 38681-38692 |
|
| Phosphatidylserinetargeted liposome for enhanced gliomaselective imaging |
|
https://doi.org/10.18632/oncotarget.9584
|
| 38693-38706 |
|
| Exosomal cancer immunotherapy is independent of MHC molecules on exosomes |
|
https://doi.org/10.18632/oncotarget.9585
|
| 38707-38717 |
|
| BCLW is a regulator of microtubule inhibitorinduced mitotic cell death |
|
https://doi.org/10.18632/oncotarget.9586
|
| 38718-38730 |
|
| Urinary mRNA biomarker panel for the detection of urothelial carcinoma |
|
https://doi.org/10.18632/oncotarget.9587
|
| 38731-38740 |
|
| Efficient role of IgH 3' regulatory region deficient Bcells in the development of oil granulomas |
|
https://doi.org/10.18632/oncotarget.9588
|
| 38741-38749 |
|
| Paf15 expression correlates with rectal cancer prognosis cell proliferation and radiation response |
|
https://doi.org/10.18632/oncotarget.9606
|
| 38750-38761 |
|
| Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma |
|
https://doi.org/10.18632/oncotarget.9607
|
| 38762-38774 |
|
| Association of HOTAIR polymorphisms rs4759314 and rs920778 with cancer susceptibility on the basis of ethnicity and cancer type |
|
https://doi.org/10.18632/oncotarget.9608
|
| 38775-38784 |
|
| Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers |
|
https://doi.org/10.18632/oncotarget.9609
|
| 38785-38795 |
|
| Indepth mapping of the mouse brain Nglycoproteome reveals widespread Nglycosylation of diverse brain proteins |
|
https://doi.org/10.18632/oncotarget.9737
|
| 38796-38809 |
|
| Technetium99mlabeled rituximab for use as a specific tracer of sentinel lymph node biopsy: a translational research study |
|
https://doi.org/10.18632/oncotarget.9614
|
| 38810-38821 |
|
| Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma |
|
https://doi.org/10.18632/oncotarget.9615
|
| 38822-38834 |
|
| Radioimmunotherapy of pancreatic cancer xenografts in nude mice using 90Ylabeled antiα6β4 integrin antibody |
|
https://doi.org/10.18632/oncotarget.9631
|
| 38835-38844 |
Clinical Research Papers
|
| Optimal surgical strategy for hepatocellular carcinoma with portal vein tumor thrombus: A propensity score analysis |
|
https://doi.org/10.18632/oncotarget.8642
|
| 38845-38856 |
|
| Alcohol and survival in ESCC: Prediagnosis alcohol consumption and postoperative survival in lymph nodenegative esophageal carcinoma patients |
|
https://doi.org/10.18632/oncotarget.8754
|
| 38857-38863 |
|
| Prognosis of subtypes of the mucinous breast carcinoma in Chinese women: a populationbased study of 32year experience 19832014 |
|
https://doi.org/10.18632/oncotarget.8778
|
| 38864-38875 |
|
| A global assessment of the male predominance in esophageal adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.9113
|
| 38876-38883 |
|
| A childhood chemotherapy protocol improves overall survival among adults with Tlymphoblastic lymphoma |
|
https://doi.org/10.18632/oncotarget.9144
|
| 38884-38891 |
Reviews
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| RASMAPK pathway epigenetic activation in cancer: miRNAs in action |
|
https://doi.org/10.18632/oncotarget.6476
|
| 38892-38907 |
|
| The sweet trap in tumors: aerobic glycolysis and potential targets for therapy |
|
https://doi.org/10.18632/oncotarget.7676
|
| 38908-38926 |
|
| Extracellular vesicle crosstalk in the bone marrow microenvironment: implications in multiple myeloma |
|
https://doi.org/10.18632/oncotarget.7792
|
| 38927-38945 |
|
| Perspectives for immunotherapy: which applications might achieve an HIV functional cure |
|
https://doi.org/10.18632/oncotarget.7793
|
| 38946-38958 |
|
| Current perspectives between metabolic syndrome and cancer |
|
https://doi.org/10.18632/oncotarget.8341
|
| 38959-38972 |
Corrections
|
| Correction: Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF1 activation in muscle |
|
https://doi.org/10.18632/oncotarget.9971
|
| 38973 |
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