Oncotarget

VOLUME 7 (2016)

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Targeting MUC1-C with GO-203 downregulates DNMT1 expression and synergistically enhances decitabine induced cell death in primary AML cells.See Tagde et al.

Table of Contents

Priority Research Papers

MUC1C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.9777
38974-38987
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Long term effects of radiation exposure on telomere lengths of leukocytes and its associated biomarkers among atomicbomb survivors

https://doi.org/10.18632/oncotarget.8801
38988-38998
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Alzheimer disease research in the 21st century: past and current failures new perspectives and funding priorities

https://doi.org/10.18632/oncotarget.9175
38999-39016
Abstract  |  PDF  |  Full Text  |  How to cite

Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt1 protein expression in young C57BL mice hearts

https://doi.org/10.18632/oncotarget.9176
39017-39025
Abstract  |  PDF  |  Full Text  |  How to cite

De novo HAPLN1 expression hallmarks Wntinduced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas

https://doi.org/10.18632/oncotarget.9346
39026-39043
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FERMT2 rs17125944 polymorphism with Alzheimer’s disease risk: a replication and metaanalysis

https://doi.org/10.18632/oncotarget.9679
39044-39050
Abstract  |  PDF  |  Full Text  |  How to cite

Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation cancer and senescence

https://doi.org/10.18632/oncotarget.9694
39051-39064
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2mediated degradation of acetylated LKB1

https://doi.org/10.18632/oncotarget.9687
39065-39081
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Runon of germline apoptosis promotes gonad senescence in C elegans

https://doi.org/10.18632/oncotarget.9681
39082-39096
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Estrogen receptor alpha inhibits senescencelike phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells

https://doi.org/10.18632/oncotarget.9772
39097-39107
Abstract  |  PDF  |  Full Text  |  How to cite

Careful neuropsychological testing reveals a novel genetic marker GSTO1*C linked to the prestage of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.9773
39108-39117
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.9776
39118-39135
Abstract  |  PDF  |  Full Text  |  How to cite

MEF2C rs190982 polymorphism with lateonset Alzheimer’s disease in Han Chinese: A replication study and metaanalyses

https://doi.org/10.18632/oncotarget.9819
39136-39142
Abstract  |  PDF  |  Full Text  |  How to cite

Agerelated increase of thromboxane B2 and risk of cardiovascular disease in atrial fibrillation

https://doi.org/10.18632/oncotarget.9826
39143-39147
Abstract  |  PDF  |  Full Text  |  How to cite

Transient enhancement of proliferation of neural progenitors and impairment of their longterm survival in p25 transgenic mice

https://doi.org/10.18632/oncotarget.9834
39148-39161
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes

https://doi.org/10.18632/oncotarget.10043
39162-39170
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL2 and IL6 cooperate to enhance the generation of influenzaspecific CD8 T cells responding to live influenza virus in aged mice and humans

https://doi.org/10.18632/oncotarget.10047
39171-39183
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

PRRT2 mutations lead to neuronal dysfunction and neurodevelopmental defects

https://doi.org/10.18632/oncotarget.9258
39184-39196
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and immunohistochemical characterization of papillary proliferation of the endometrium: A single institutional experience

https://doi.org/10.18632/oncotarget.10049
39197-39206
Abstract  |  PDF  |  Full Text  |  How to cite

TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes

https://doi.org/10.18632/oncotarget.9393
39207-39215
Abstract  |  PDF  |  Full Text  |  How to cite

The comprehensive summary of surgical versus nonsurgical treatment for obesity: a systematic review and metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.9581
39216-39230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The associations between serum biomarkers and stenosis of the coronary arteries

https://doi.org/10.18632/oncotarget.9645
39231-39240
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas

https://doi.org/10.18632/oncotarget.9649
39241-39255
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dendritic cellderived VEGFA plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors

https://doi.org/10.18632/oncotarget.9684
39256-39269
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Toxicological assessment of multiwalled carbon nanotubes in vitro: potential mitochondria effects on male reproductive cells

https://doi.org/10.18632/oncotarget.9689
39270-39278
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ATG4A promotes tumor metastasis by inducing the epithelialmesenchymal transition and stemlike properties in gastric cells

https://doi.org/10.18632/oncotarget.9827
39279-39292
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mutations of KRAS NRAS BRAF EGFR and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance

https://doi.org/10.18632/oncotarget.9828
39293-39301
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Treatment of diabetes mellitusinduced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase

https://doi.org/10.18632/oncotarget.9909
39302-39315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of NLRP3 inflammasomes in mouse hepatic stellate cells during Schistosoma J infection

https://doi.org/10.18632/oncotarget.10044
39316-39331
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analysis of the correlation between lipotoxicity and pituitarythyroid axis hormone levels in men and male rats

https://doi.org/10.18632/oncotarget.10045
39332-39344
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of volumesensitive Cl channel mediates autophagyrelated cell death in myocardial ischaemia/reperfusion injury

https://doi.org/10.18632/oncotarget.10050
39345-39362
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related smallmolecule inhibitor pterostilbene

https://doi.org/10.18632/oncotarget.8101
39363-39375
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunoproteomic identification of MbovP579 a promising diagnostic biomarker for serological detection of Mycoplasma bovis infection

https://doi.org/10.18632/oncotarget.9799
39376-39395
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence

https://doi.org/10.18632/oncotarget.9818
39396-39407
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Immunoglobulin G promotes skin graft acceptance in an immunologically potent rat model

https://doi.org/10.18632/oncotarget.9823
39408-39420
Abstract  |  PDF  |  Full Text  |  How to cite

Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation

https://doi.org/10.18632/oncotarget.9820
39421-39435
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of FCGR2A rs1801274 polymorphism with susceptibility to autoimmune diseases: A metaanalysis

https://doi.org/10.18632/oncotarget.9831
39436-39443
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Neuroscience

5d a novel analogue of 3nbutylphthalide decreases NADPH oxidase activity through the positive regulation of CK2 after ischemia/reperfusion injury

https://doi.org/10.18632/oncotarget.8548
39444-39457
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Reactivation of Smacmediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic

https://doi.org/10.18632/oncotarget.8462
39458-39472
Abstract  |  PDF  |  Full Text  |  How to cite

Mitochondrial oxidative phosphorylation controls cancer cell’s life and death decisions upon exposure to MAPK inhibitors

https://doi.org/10.18632/oncotarget.7790
39473-39485
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heparanase expression upregulates platelet adhesion activity and thrombogenicity

https://doi.org/10.18632/oncotarget.8960
39486-39496
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Paeonol protects endotoxininduced acute kidney injury: potential mechanism of inhibiting TLR4NFκB signal pathway

https://doi.org/10.18632/oncotarget.8347
39497-39510
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA26b inhibits tumor metastasis by targeting the KPNA2/cjun pathway in human gastric cancer

https://doi.org/10.18632/oncotarget.8629
39511-39526
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR590 promotes cell proliferation and invasion in Tcell acute lymphoblastic leukaemia by inhibiting RB1

https://doi.org/10.18632/oncotarget.8414
39527-39534
Abstract  |  PDF  |  Full Text  |  How to cite

Plasma dynamic monitoring of soluble cMet level for EGFRTKI treatment in advanced nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.9425
39535-39543
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in earlystage nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.9647
39544-39555
Abstract  |  PDF  |  Full Text  |  How to cite

Cytoplasmic full length and novel cleaved variant TBLR1 reduces apoptosis in prostate cancer under androgen deprivation

https://doi.org/10.18632/oncotarget.9005
39556-39571
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms in the CHIT1 gene: Associations with colorectal cancer

https://doi.org/10.18632/oncotarget.9138
39572-39581
Abstract  |  PDF  |  Full Text  |  How to cite

The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer

https://doi.org/10.18632/oncotarget.8659
39582-39594
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models

https://doi.org/10.18632/oncotarget.9153
39595-39608
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9203
39609-39626
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interference with mutagenic aflatoxin B1induced checkpoints through antagonistic action of ochratoxin A in intestinal cancer cells: a molecular explanation on potential risk of crosstalk between carcinogens

https://doi.org/10.18632/oncotarget.8914
39627-39639
Abstract  |  PDF  |  Full Text  |  How to cite

Small RNAs and the competing endogenous RNA network in high grade serous ovarian cancer tumor spread

https://doi.org/10.18632/oncotarget.9243
39640-39653
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Minimal contribution of ERK1/2MAPK signalling towards the maintenance of oncogenic GNAQQ209Pdriven uveal melanomas in zebrafish

https://doi.org/10.18632/oncotarget.9207
39654-39670
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Programmed deathligand1 expression in advanced gastric cancer detected with RNA in situ hybridization and its clinical significance

https://doi.org/10.18632/oncotarget.9381
39671-39679
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR193a5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9444
39680-39693
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pinin associates with prognosis of hepatocellular carcinoma through promoting cell proliferation and suppressing glucose deprivationinduced apoptosis

https://doi.org/10.18632/oncotarget.9233
39694-39704
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycle

https://doi.org/10.18632/oncotarget.9451
39705-39718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Homeobox protein VentX induces p53independent apoptosis in cancer cells

https://doi.org/10.18632/oncotarget.9238
39719-39729
Abstract  |  PDF  |  Full Text  |  How to cite

MEK inhibitor PD0325901 and vitamin C synergistically induce hypomethylation of mouse embryonic stem cells

https://doi.org/10.18632/oncotarget.9452
39730-39739
Abstract  |  PDF  |  Full Text  |  How to cite

Downregulation of microRNA320 suppresses cardiomyocyte apoptosis and protects against myocardial ischemia and reperfusion injury by targeting IGF1

https://doi.org/10.18632/oncotarget.9240
39740-39757
Abstract  |  PDF  |  Full Text  |  How to cite

The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas

https://doi.org/10.18632/oncotarget.9250
39758-39767
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorselective replication herpes simplex virusbased technology significantly improves clinical detection and prognostication of viable circulating tumor cells

https://doi.org/10.18632/oncotarget.9465
39768-39783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection

https://doi.org/10.18632/oncotarget.9289
39784-39795
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin1 via an increase in ROS and activation of NFκB

https://doi.org/10.18632/oncotarget.9290
39796-39808
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumabpaclitaxel neoadjuvant therapy in HER2 positive breast cancer

https://doi.org/10.18632/oncotarget.9489
39809-39822
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy of epidermal growth factor receptor inhibitors in combination with chemotherapy in advanced nonsmall cell lung cancer: A metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.9503
39823-39833
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling

https://doi.org/10.18632/oncotarget.9405
39834-39845
Abstract  |  PDF  |  Full Text  |  How to cite

Tumortropic endothelial colony forming cells ECFCs loaded with nearinfrared sensitive Au nanoparticles: A “cellular stove” approach to the photoablation of melanoma

https://doi.org/10.18632/oncotarget.9511
39846-39860
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap FP1039/GSK3052230

https://doi.org/10.18632/oncotarget.9515
39861-39871
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FKBP14 overexpression contributes to osteosarcoma carcinogenesis and indicates poor survival outcome

https://doi.org/10.18632/oncotarget.9524
39872-39884
Abstract  |  PDF  |  Full Text  |  How to cite

Microsatellite instability derived JAK1 frameshift mutations are associated with tumor immune evasion in endometrioid endometrial cancer

https://doi.org/10.18632/oncotarget.9414
39885-39893
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activated dendritic cells delivered in tissue compatible biomatrices induce insitu antitumor CTL responses leading to tumor regression

https://doi.org/10.18632/oncotarget.9529
39894-39906
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA613 inhibits cell growth migration and invasion of papillary thyroid carcinoma by regulating SphK2

https://doi.org/10.18632/oncotarget.9530
39907-39915
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorinfiltrating immune cell subpopulations influence the oncologic outcome after intravesical Bacillus CalmetteGuérin therapy in bladder cancer

https://doi.org/10.18632/oncotarget.9537
39916-39930
Abstract  |  PDF  |  Full Text  |  How to cite

Screenidentified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance

https://doi.org/10.18632/oncotarget.9539
39931-39944
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of preoperative serum lactate dehydrogenase levels for resectable gastric cancer and prognostic nomograms

https://doi.org/10.18632/oncotarget.9459
39945-39956
Abstract  |  PDF  |  Full Text  |  How to cite

Expression of the receptor for hyaluronic acid mediated motility RHAMM is associated with poor prognosis and metastasis in nonsmall cell lung carcinoma

https://doi.org/10.18632/oncotarget.9554
39957-39969
Abstract  |  PDF  |  Full Text  |  How to cite

SCD1 is associated with tumor promotion late stage and poor survival in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.9461
39970-39979
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin

https://doi.org/10.18632/oncotarget.9556
39980-39995
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of FRA1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis

https://doi.org/10.18632/oncotarget.9557
39996-40011
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential association for Nacetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population

https://doi.org/10.18632/oncotarget.9475
40012-40024
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Higher methylation intensity induced by EBV LMP1 via NFκB/DNMT3b signaling contributes to silencing of PTEN gene

https://doi.org/10.18632/oncotarget.9474
40025-40037
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA138 acts as a tumor suppressor in non small cell lung cancer via targeting YAP1

https://doi.org/10.18632/oncotarget.9480
40038-40046
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A transferrintarget magnetic/fluorescent dualmode probe significantly enhances the diagnosis of nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.9482
40047-40059
Abstract  |  PDF  |  Full Text  |  How to cite

Activin B promotes endometrial cancer cell migration by downregulating Ecadherin via SMADindependent MEKERK1/2SNAIL signaling

https://doi.org/10.18632/oncotarget.9483
40060-40072
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Everolimus induces Met inactivation by disrupting the FKBP12/Met complex

https://doi.org/10.18632/oncotarget.9484
40073-40084
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Predictors of longterm response to abiraterone in patients with metastastic castrationresistant prostate cancer: a retrospective cohort study

https://doi.org/10.18632/oncotarget.9485
40085-40094
Abstract  |  PDF  |  Full Text  |  How to cite

Tailored multimodality therapy guided by a twostep decision making process for headandneck cancer of unknown primary

https://doi.org/10.18632/oncotarget.9492
40095-40105
Abstract  |  PDF  |  Full Text  |  How to cite

Soluble Tolllike receptor 4 is a potential serum biomarker in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.9496
40106-40114
Abstract  |  PDF  |  Full Text  |  How to cite

Preclinical efficacy and synergistic potential of the MDM2p53 antagonists Nutlin3 and RG7388 as single agents and in combined treatment with cisplatin in ovarian cancer

https://doi.org/10.18632/oncotarget.9499
40115-40134
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Variants in human papillomavirus receptor and associated genes are associated with typespecific HPV infection and lesion progression of the cervix

https://doi.org/10.18632/oncotarget.9510
40135-40147
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Periostin promotes tumor angiogenesis in pancreatic cancer via Erk/VEGF signaling

https://doi.org/10.18632/oncotarget.9512
40148-40159
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tspan5 is an independent favourable prognostic factor and suppresses tumour growth in gastric cancer

https://doi.org/10.18632/oncotarget.9514
40160-40173
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BKCa promotes growth and metastasis of prostate cancer through facilitating the coupling between αvβ3 integrin and FAK

https://doi.org/10.18632/oncotarget.9559
40174-40188
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fibronectin on circulating extracellular vesicles as a liquid biopsy to detect breast cancer

https://doi.org/10.18632/oncotarget.9561
40189-40199
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Big data and computational biology strategy for personalized prognosis

https://doi.org/10.18632/oncotarget.9571
40200-40220
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluating L1CAM expression in human endometrial cancer using qRTPCR

https://doi.org/10.18632/oncotarget.9574
40221-40232
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Indolin2one compounds targeting thioredoxin reductase as potential anticancer drug leads

https://doi.org/10.18632/oncotarget.9579
40233-40251
Abstract  |  PDF  |  Full Text  |  How to cite

Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT

https://doi.org/10.18632/oncotarget.9730
40252-40265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

JARID2 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelialmesenchymal transition through PTEN/AKT signaling

https://doi.org/10.18632/oncotarget.9733
40266-40284
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Isoliensinine induces dephosphorylation of NFkB p65 subunit at Ser536 via a PP2Adependent mechanism in hepatocellular carcinoma cells: roles of impairing PP2A/I2PP2A interaction

https://doi.org/10.18632/oncotarget.9603
40285-40296
Abstract  |  PDF  |  Full Text  |  How to cite

MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features

https://doi.org/10.18632/oncotarget.9610
40297-40313
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miRNA3373p inhibits gastric cancer progression through repressing myeloid zinc finger 1facilitated expression of matrix metalloproteinase 14

https://doi.org/10.18632/oncotarget.9739
40314-40328
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting FOSB with a cationic antimicrobial peptide TP4 for treatment of triplenegative breast cancer

https://doi.org/10.18632/oncotarget.9612
40329-40347
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics

https://doi.org/10.18632/oncotarget.9613
40348-40361
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cdc6 contributes to cisplatinresistance by activation of ATRChk1 pathway in bladder cancer cells

https://doi.org/10.18632/oncotarget.9616
40362-40376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of nonsmall cell lung cancer via the ERK1/2/MMP9 pathway

https://doi.org/10.18632/oncotarget.9750
40377-40386
Abstract  |  PDF  |  Full Text  |  How to cite

Integrin alphavbeta3 enhances βcatenin signaling in acute myeloid leukemia harboring Fmslike tyrosine kinase3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity

https://doi.org/10.18632/oncotarget.9617
40387-40397
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Multikinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.9752
40398-40417
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional and prognostic significance of long noncoding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer

https://doi.org/10.18632/oncotarget.9622
40418-40436
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel peptide targeting Clec9a on dendritic cell for cancer immunotherapy

https://doi.org/10.18632/oncotarget.9624
40437-40450
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inverse role of distinct subsets and distribution of macrophage in lung cancer prognosis: a metaanalysis

https://doi.org/10.18632/oncotarget.9625
40451-40460
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Transcriptomic and proteomic analysis of mouse radiationinduced acute myeloid leukaemia AML

https://doi.org/10.18632/oncotarget.9626
40461-40480
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Noninvasive detection of tumorassociated mutations from circulating cellfree DNA in hepatocellular carcinoma patients by targeted deep sequencing

https://doi.org/10.18632/oncotarget.9629
40481-40490
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European American populations

https://doi.org/10.18632/oncotarget.9636
40491-40499
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic polymorphisms in TNIP1 increase the risk of gastric carcinoma

https://doi.org/10.18632/oncotarget.9637
40500-40507
Abstract  |  PDF  |  Full Text  |  How to cite

TREM1low is a novel characteristic for tumorassociated macrophages in lung cancer

https://doi.org/10.18632/oncotarget.9639
40508-40517
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation

https://doi.org/10.18632/oncotarget.9642
40518-40530
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models

https://doi.org/10.18632/oncotarget.9643
40531-40545
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mesenchymal stem celllike properties of CD133+ glioblastoma initiating cells

https://doi.org/10.18632/oncotarget.9658
40546-40557
Abstract  |  PDF  |  Full Text  |  How to cite

Phenotypic alteration of CD8+ T cells in chronic lymphocytic leukemia is associated with epigenetic reprogramming

https://doi.org/10.18632/oncotarget.9941
40558-40570
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extracellular matrixspecific Caveolin1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis

https://doi.org/10.18632/oncotarget.9738
40571-40593
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5fluorouracilresistant colon cancer cells

https://doi.org/10.18632/oncotarget.9745
40594-40620
Abstract  |  PDF  |  Full Text  |  How to cite

Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation

https://doi.org/10.18632/oncotarget.9746
40621-40629
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tetraspanin8 promotes hepatocellular carcinoma metastasis by increasing ADAM12m expression

https://doi.org/10.18632/oncotarget.9769
40630-40643
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA375 suppresses human colorectal cancer metastasis by targeting Frizzled 8

https://doi.org/10.18632/oncotarget.9811
40644-40656
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

microRNA558 facilitates the expression of hypoxiainducible factor 2 alpha through binding to 5′untranslated region in neuroblastoma

https://doi.org/10.18632/oncotarget.9813
40657-40673
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of glycolysis and oxidative phosphorylation in benzo[α]pyrene and arsenicinduced rat lung epithelial transformed cells

https://doi.org/10.18632/oncotarget.9814
40674-40689
Abstract  |  PDF  |  Full Text  |  How to cite

Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor

https://doi.org/10.18632/oncotarget.9816
40690-40703
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/βcatenin signaling

https://doi.org/10.18632/oncotarget.9930
40704-40718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Multicentric survey on dose reduction/interruption of cancer drug therapy in 12472 patients: indicators of suspected adverse reactions

https://doi.org/10.18632/oncotarget.8942
40719-40724
Abstract  |  PDF  |  Full Text  |  How to cite

High temperature requirement A3 HTRA3 expression predicts postoperative recurrence and survival in patients with nonsmallcell lung cancer

https://doi.org/10.18632/oncotarget.9173
40725-40734
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinicopathological features and prognosis of colonic gastrointestinal stromal tumors: evaluation of a pooled case series

https://doi.org/10.18632/oncotarget.9196
40735-40745
Abstract  |  PDF  |  Full Text  |  How to cite

Radiobiological modeling of two stereotactic body radiotherapy schedules in patients with stage I peripheral nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.9442
40746-40755
Abstract  |  PDF  |  Full Text  |  How to cite

Phase I doseescalation study of helical intensitymodulated radiotherapybased stereotactic body radiotherapy for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9450
40756-40766
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Repurposing metformin for cancer treatment: current clinical studies

https://doi.org/10.18632/oncotarget.8194
40767-40780
Abstract  |  PDF  |  Full Text  |  How to cite

Addressing the elephant in the room therapeutic resistance in nonsmall cell lung cancer with epigenetic therapies

https://doi.org/10.18632/oncotarget.8205
40781-40791
Abstract  |  PDF  |  Full Text  |  How to cite

Tall cell variant of papillary thyroid carcinoma: current evidence on clinicopathologic features and molecular biology

https://doi.org/10.18632/oncotarget.8215
40792-40799
Abstract  |  PDF  |  Full Text  |  How to cite

Tetrandrine a Chinese plantderived alkaloid is a potential candidate for cancer chemotherapy

https://doi.org/10.18632/oncotarget.8315
40800-40815
Abstract  |  PDF  |  Full Text  |  How to cite

Multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus – Eastern Hepatobiliary Surgical Hospital consensus statement

https://doi.org/10.18632/oncotarget.8386
40816-40829
Abstract  |  PDF  |  Full Text  |  How to cite

Adipogenic miRNA and metasignature miRNAs involved in human adipocyte differentiation and obesity

https://doi.org/10.18632/oncotarget.8518
40830-40845
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The emerging roles and therapeutic potential of cyclindependent kinase 11 CDK11 in human cancer

https://doi.org/10.18632/oncotarget.8519
40846-40859
Abstract  |  PDF  |  Full Text  |  How to cite

Neuraminidase1: A novel therapeutic target in multistage tumorigenesis

https://doi.org/10.18632/oncotarget.8396
40860-40881
Abstract  |  PDF  |  Full Text  |  How to cite

Engineered nanoparticles induce cell apoptosis: potential for cancer therapy

https://doi.org/10.18632/oncotarget.8553
40882-40903
Abstract  |  PDF  |  Full Text  |  How to cite


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