Oncotarget

VOLUME 7 (2016)

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CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways. See Schulte et al.

 

Table of Contents

Editorial

Targeting MITF in the tolerancephase

https://doi.org/10.18632/oncotarget.9423
54094-54095
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Research Perspectives

Metformin and cancer: Quo vadis et cui bono

https://doi.org/10.18632/oncotarget.10262
54096-54101
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Priority Research Papers

Novel function of MDA9/Syntenin SDCBP as a regulator of survival and stemness in glioma stem cells

https://doi.org/10.18632/oncotarget.10851
54102-54119
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations

https://doi.org/10.18632/oncotarget.10852
54120-54136
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EGFRtargeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models

https://doi.org/10.18632/oncotarget.11021
54137-54156
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis

https://doi.org/10.18632/oncotarget.11022
54157-54173
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias

https://doi.org/10.18632/oncotarget.11099
54174-54182
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Royal jelly promotes DAF16mediated proteostasis to tolerate βamyloid toxicity in C elegans model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.10857
54183-54193
Abstract  |  PDF  |  Full Text  |  How to cite

Age is associated with time in therapeutic range for warfarin therapy in patients with atrial fibrillation

https://doi.org/10.18632/oncotarget.10944
54194-54199
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Dosedependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer’s disease

https://doi.org/10.18632/oncotarget.11027
54200-54214
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson’s disease

https://doi.org/10.18632/oncotarget.11090
54215-54227
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

FOXC2 diseasemutations identified in lymphedemadistichiasis patients cause both loss and gain of protein function

https://doi.org/10.18632/oncotarget.9797
54228-54239
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

https://doi.org/10.18632/oncotarget.11095
54240-54252
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9801
54253-54262
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension

https://doi.org/10.18632/oncotarget.10855
54263-54273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency

https://doi.org/10.18632/oncotarget.11026
54274-54289
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NLRP3 inflammasome activation is involved in Ang IIinduced kidney damage via mitochondrial dysfunction

https://doi.org/10.18632/oncotarget.11091
54290-54302
Abstract  |  PDF  |  Full Text  |  How to cite

Binge ethanol exposure causes endoplasmic reticulum stress oxidative stress and tissue injury in the pancreas

https://doi.org/10.18632/oncotarget.11103
54303-54316
Abstract  |  PDF  |  Full Text  |  How to cite

Prolyl hydroxylase 2 PHD2 inhibition protects human renal epithelial cells and mice kidney from hypoxia injury

https://doi.org/10.18632/oncotarget.11104
54317-54328
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Towards a multi protein and mRNA expression of biological predictive and distinguish model for post stroke depression

https://doi.org/10.18632/oncotarget.11105
54329-54338
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance

https://doi.org/10.18632/oncotarget.10913
54339-54359
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of specific allergen and probiotics induces specific regulatory B cells and enhances specific immunotherapy effect on allergic rhinitis

https://doi.org/10.18632/oncotarget.10946
54360-54369
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ADAR1 is vital for B cell lineage development in the mouse bone marrow

https://doi.org/10.18632/oncotarget.11029
54370-54379
Abstract  |  PDF  |  Full Text  |  How to cite

Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals

https://doi.org/10.18632/oncotarget.11092
54380-54391
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myeloid cell expressed proprotein convertase FURIN attenuates inflammation

https://doi.org/10.18632/oncotarget.11106
54392-54404
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Research Papers

White matter degeneration in subjective cognitive decline: a diffusion tensor imaging study

https://doi.org/10.18632/oncotarget.10091
54405-54414
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of the neonatal Fc receptor expression in nonsmall cell lung cancer tissue is associated with a poor prognosis

https://doi.org/10.18632/oncotarget.10074
54415-54429
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Scaffold attachment factor A SAFA and Ku temporally regulate repair of radiationinduced clustered genome lesions

https://doi.org/10.18632/oncotarget.9914
54430-54444
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Importance of the type I insulinlike growth factor receptor in HER2 FGFR2 and METunamplified gastric cancer with and without Ras pathway activation

https://doi.org/10.18632/oncotarget.10642
54445-54462
Abstract  |  PDF  |  Full Text  |  How to cite

Polypeptide Nacetylgalactosaminyltransferase6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection

https://doi.org/10.18632/oncotarget.9810
54463-54473
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The urokinase receptorderived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells

https://doi.org/10.18632/oncotarget.9976
54474-54487
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of PLIN1 expression in human breast cancer

https://doi.org/10.18632/oncotarget.10239
54488-54502
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miRNA193a5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors

https://doi.org/10.18632/oncotarget.10950
54503-54514
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crizotinib inhibits NF2associated schwannoma through inhibition of focal adhesion kinase 1

https://doi.org/10.18632/oncotarget.10248
54515-54525
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection

https://doi.org/10.18632/oncotarget.9440
54526-54536
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Induction of apoptosis and autophagy via mitochondria and PI3K/Akt/mTORmediated pathways by E adenophorum in hepatocytes of saanen goat

https://doi.org/10.18632/oncotarget.10402
54537-54548
Abstract  |  PDF  |  Full Text  |  How to cite

Artificial small RNA for sequence specific cleavage of target RNA through RNase III endonuclease Dicer

https://doi.org/10.18632/oncotarget.9582
54549-54554
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Independent evaluation of a FOXM1based quantitative malignancy diagnostic system qMIDS on head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.10512
54555-54563
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systemic immuneinflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

https://doi.org/10.18632/oncotarget.10515
54564-54571
Abstract  |  PDF  |  Full Text  |  How to cite

Posttranscriptional knowledge in pathway analysis increases the accuracy of phenotypes classification

https://doi.org/10.18632/oncotarget.9788
54572-54582
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma

https://doi.org/10.18632/oncotarget.10518
54583-54595
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The downregulated ING5 expression in lung cancer: A potential target of gene therapy

https://doi.org/10.18632/oncotarget.10519
54596-54615
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer

https://doi.org/10.18632/oncotarget.10520
54616-54626
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MET amplification in metastatic colorectal cancer: an acquired response to EGFR inhibition not a de novo phenomenon

https://doi.org/10.18632/oncotarget.10559
54627-54631
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Annexin 2A sustains glioblastoma cell dissemination and proliferation

https://doi.org/10.18632/oncotarget.10565
54632-54649
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Specific patterns of PIWIinteracting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10567
54650-54661
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Surgical resection and radiofrequency ablation initiate cancer in cytokeratin19+ liver cells deficient for p53 and Rb

https://doi.org/10.18632/oncotarget.9952
54662-54675
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation

https://doi.org/10.18632/oncotarget.10578
54676-54690
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glutamine deprivation plus BPTES alters etoposide and cisplatininduced apoptosis in triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.10579
54691-54701
Abstract  |  PDF  |  Full Text  |  How to cite

Gallic acid inhibition of SrcStat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.10581
54702-54713
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

HDAC6 inhibition prevents TNFαinduced caspase 3 activation in lung endothelial cell and maintains cellcell junctions

https://doi.org/10.18632/oncotarget.10591
54714-54722
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of primary breast tumor growth and metastasis using a neuropilin1 transmembrane domain interfering peptide

https://doi.org/10.18632/oncotarget.10101
54723-54732
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A

https://doi.org/10.18632/oncotarget.10752
54733-54743
Abstract  |  PDF  |  Full Text  |  How to cite

PAX3 is a novel tumor suppressor by regulating the activities of major signaling pathways and transcription factor FOXO3a in thyroid cancer

https://doi.org/10.18632/oncotarget.10753
54744-54757
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma

https://doi.org/10.18632/oncotarget.10181
54758-54770
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association between single nucleotide polymorphisms in the TSPYL6 gene and breast cancer susceptibility in the Han Chinese population

https://doi.org/10.18632/oncotarget.10754
54771-54781
Abstract  |  PDF  |  Full Text  |  How to cite

Cooperation between AlphavBeta3 integrin and the fibroblast growth factor receptor enhances proliferation of Hoxoverexpressing acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.10189
54782-54794
Abstract  |  PDF  |  Full Text  |  How to cite

Hypoxiatargeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cellmediated sodium iodide symporter gene delivery

https://doi.org/10.18632/oncotarget.10758
54795-54810
Abstract  |  PDF  |  Full Text  |  How to cite

Regression of experimental NISexpressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy

https://doi.org/10.18632/oncotarget.10238
54811-54824
Abstract  |  PDF  |  Full Text  |  How to cite

Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations

https://doi.org/10.18632/oncotarget.10240
54825-54837
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR34b3 and miR449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A

https://doi.org/10.18632/oncotarget.10761
54838-54851
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lung cancer exosomes as drivers of epithelial mesenchymal transition

https://doi.org/10.18632/oncotarget.10243
54852-54866
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic similarity between gastroesophageal junction and esophageal Barrett’s adenocarcinomas

https://doi.org/10.18632/oncotarget.10253
54867-54882
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition

https://doi.org/10.18632/oncotarget.10702
54883-54896
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PIM kinases as therapeutic targets against advanced melanoma

https://doi.org/10.18632/oncotarget.10703
54897-54912
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MIEN1 drives breast tumor cell migration by regulating cytoskeletalfocal adhesion dynamics

https://doi.org/10.18632/oncotarget.10798
54913-54924
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Photoimmunotheranostic agents for triplenegative breast cancer diagnosis and therapy that can be activated on demand

https://doi.org/10.18632/oncotarget.10705
54925-54936
Abstract  |  PDF  |  Full Text  |  How to cite

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4

https://doi.org/10.18632/oncotarget.10709
54937-54951
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor growth accelerated by chemotherapyinduced senescent cells is suppressed by treatment with IL12 producing cellular vaccines

https://doi.org/10.18632/oncotarget.10712
54952-54964
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plasma MiRNA alterations between NSCLC patients harboring Del19 and L858R EGFR mutations

https://doi.org/10.18632/oncotarget.10829
54965-54972
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of CDX2 in gastric cardia adenocarcinoma and its correlation with H pylori and cell proliferation

https://doi.org/10.18632/oncotarget.10362
54973-54982
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NHERF1 a novel GPER associated protein increases stability and activation of GPER in ERpositive breast cancer

https://doi.org/10.18632/oncotarget.10713
54983-54997
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR328 targeting PIM1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway

https://doi.org/10.18632/oncotarget.10714
54998-55011
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs

https://doi.org/10.18632/oncotarget.10839
55012-55025
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CNS germinomas are characterized by global demethylation chromosomal instability and mutational activation of the Kit Ras/Raf/Erk and Aktpathways

https://doi.org/10.18632/oncotarget.10392
55026-55042
Abstract  |  PDF  |  Full Text  |  How to cite

Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells

https://doi.org/10.18632/oncotarget.10393
55043-55056
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin increases PDH and suppresses HIF1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10842
55057-55068
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castrationresistant prostate cancer: a report from the PETRUS prospective study

https://doi.org/10.18632/oncotarget.10396
55069-55082
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MLN0128 a novel mTOR kinase inhibitor disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells

https://doi.org/10.18632/oncotarget.10397
55083-55097
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor LINE1 methylation level and colorectal cancer location in relation to patient survival

https://doi.org/10.18632/oncotarget.10398
55098-55109
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Carboxylterminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10399
55110-55127
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1beta in melanoma

https://doi.org/10.18632/oncotarget.10422
55128-55140
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting αvβ3 and αvβ5 integrins inhibits pulmonary metastasis in an intratibial xenograft osteosarcoma mouse model

https://doi.org/10.18632/oncotarget.10461
55141-55154
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer

https://doi.org/10.18632/oncotarget.10894
55155-55168
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sexspecific clinicopathological significance of novel Frizzled7 and established MGMT IDH1 biomarkers in glioblastoma

https://doi.org/10.18632/oncotarget.10465
55169-55180
Abstract  |  PDF  |  Full Text  |  How to cite

Serum neuronspecific enolase levels are upregulated in patients with acute lymphoblastic leukemia and are predictive of prognosis

https://doi.org/10.18632/oncotarget.10473
55181-55190
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

1433ζ and aPKCι synergistically facilitate epithelialmesenchymal transition of cholangiocarcinoma via GSK3β/Snail signaling pathway

https://doi.org/10.18632/oncotarget.10483
55191-55210
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nomogram and recursive partitioning analysis to predict overall survival in patients with stage IIBIII thoracic esophageal squamous cell carcinoma after esophagectomy

https://doi.org/10.18632/oncotarget.10904
55211-55221
Abstract  |  PDF  |  Full Text  |  How to cite

Altered phenotypic and functional characteristics of CD3+CD56+ NKTlike cells in human gastric cancer

https://doi.org/10.18632/oncotarget.10484
55222-55230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients

https://doi.org/10.18632/oncotarget.10485
55231-55248
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metadimensional data integration identifies critical pathways for susceptibility tumorigenesis and progression of endometrial cancer

https://doi.org/10.18632/oncotarget.10509
55249-55263
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome

https://doi.org/10.18632/oncotarget.10526
55264-55275
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of neural cell adhesion molecule L1 CD171 in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.10527
55276-55289
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer

https://doi.org/10.18632/oncotarget.10528
55290-55301
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development

https://doi.org/10.18632/oncotarget.10878
55302-55312
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The human Smoothened inhibitor PF04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells

https://doi.org/10.18632/oncotarget.10879
55313-55327
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD109 is identified as a potential nasopharyngeal carcinoma biomarker using aptamer selected by cellSELEX

https://doi.org/10.18632/oncotarget.10530
55328-55342
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel gene expressionbased prognostic scoring system to predict survival in gastric cancer

https://doi.org/10.18632/oncotarget.10533
55343-55351
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data

https://doi.org/10.18632/oncotarget.10536
55352-55367
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Incidence and origin of histologically confirmed liver metastases: an explorative casestudy of 23154 patients

https://doi.org/10.18632/oncotarget.10552
55368-55376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of biomarkers for pseudo and true progression of GBM based on radiogenomics study

https://doi.org/10.18632/oncotarget.10553
55377-55394
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA fingerprints in juvenile myelomonocytic leukemia JMML identified miR1505p as a tumor suppressor and potential target for treatment

https://doi.org/10.18632/oncotarget.10577
55395-55408
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD44v6competent tumor exosomes promote motility invasion and cancerinitiating cell marker expression in pancreatic and colorectal cancer cells

https://doi.org/10.18632/oncotarget.10580
55409-55436
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis

https://doi.org/10.18632/oncotarget.10583
55437-55448
Abstract  |  PDF  |  Full Text  |  How to cite

ABCC224C > T polymorphism is associated with the response to platinum/5Fubased neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients

https://doi.org/10.18632/oncotarget.10961
55449-55457
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Thromboxane A2 receptor TBXA2R is a potent survival factor for triple negative breast cancers TNBCs

https://doi.org/10.18632/oncotarget.10969
55458-55472
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Monocytederived factors including PLA2G7 induced by macrophagenasopharyngeal carcinoma cell interaction promote tumor cell invasiveness

https://doi.org/10.18632/oncotarget.10980
55473-55490
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Insulinlike growth factor binding protein3 links obesity and breast cancer progression

https://doi.org/10.18632/oncotarget.10675
55491-55505
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of brainderived neurotrophic factor in advanced gastric cancer contributes to bone metastatic osteolysis by inducing long pentraxin 3

https://doi.org/10.18632/oncotarget.10747
55506-55517
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer by downregulating its cognate gene CTNNA1 expression

https://doi.org/10.18632/oncotarget.10833
55518-55528
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The application of mRNAbased gene transfer in mesenchymal stem cellmediated cytotoxicity of glioma cells

https://doi.org/10.18632/oncotarget.10835
55529-55542
Abstract  |  PDF  |  Full Text  |  How to cite

A FASNTGFβ1FASN regulatory loop contributes to high EMT/metastatic potential of cisplatinresistant nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.10837
55543-55554
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting hyperactivated DNAPKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling

https://doi.org/10.18632/oncotarget.10864
55555-55571
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrin β3 and CD44 levels determine the effects of the OPNa splicing variant on lung cancer cell growth

https://doi.org/10.18632/oncotarget.10865
55572-55584
Abstract  |  PDF  |  Full Text  |  How to cite

YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10866
55585-55600
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Decreased expression of FOXF2 as new predictor of poor prognosis in stage I nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.10876
55601-55610
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The associations between MDM4 gene polymorphisms and cancer risk

https://doi.org/10.18632/oncotarget.10877
55611-55623
Abstract  |  PDF  |  Full Text  |  How to cite

HypoxiaNOTCH1SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer

https://doi.org/10.18632/oncotarget.10954
55624-55638
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response

https://doi.org/10.18632/oncotarget.10956
55639-55648
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

S18 family of mitochondrial ribosomal proteins: evolutionary history and Gly132 polymorphism in colon carcinoma

https://doi.org/10.18632/oncotarget.10957
55649-55662
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD24 promoted cancer cell angiogenesis via Hsp90mediated STAT3/VEGF signaling pathway in colorectal cancer

https://doi.org/10.18632/oncotarget.10971
55663-55676
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma

https://doi.org/10.18632/oncotarget.10972
55677-55689
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in Tcell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.10984
55690-55703
Abstract  |  PDF  |  Full Text  |  How to cite

The transmembrane domain of Bcl2α but not its hydrophobic cleft is a critical determinant for efficient IP3 receptor inhibition

https://doi.org/10.18632/oncotarget.11005
55704-55720
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Efficacy and safety of cisplatin dexamethasone gemcitabine and pegaspargase DDGP regimen in newly diagnosed advancedstage extranodal natural killer/Tcell lymphoma: interim analysis of a phase 4 study NCT01501149

https://doi.org/10.18632/oncotarget.10124
55721-55731
Abstract  |  PDF  |  Full Text  |  How to cite

Chemotherapy plus targeted drugs in conversion therapy for potentially resectable colorectal liver metastases: a metaanalysis

https://doi.org/10.18632/oncotarget.9675
55732-55740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pharmacogenomics of platinumbased chemotherapy response in NSCLC: a genotyping study and a pooled analysis

https://doi.org/10.18632/oncotarget.9688
55741-55756
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TCF21 genetic polymorphisms and breast cancer risk in Chinese women

https://doi.org/10.18632/oncotarget.9825
55757-55764
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Elevated serum Creactive protein level predicts a poor prognosis for recurrent gastric cancer

https://doi.org/10.18632/oncotarget.9910
55765-55770
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Targeting epithelialmesenchymal transition and cancer stem cells for chemoresistant ovarian cancer

https://doi.org/10.18632/oncotarget.9908
55771-55788
Abstract  |  PDF  |  Full Text  |  How to cite

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target

https://doi.org/10.18632/oncotarget.10048
55789-55810
Abstract  |  PDF  |  Full Text  |  How to cite

Sulfonation an underexploited area: from skeletal development to infectious diseases and cancer

https://doi.org/10.18632/oncotarget.10046
55811-55827
Abstract  |  PDF  |  Full Text  |  How to cite

Positive and negative functions of B lymphocytes in tumors

https://doi.org/10.18632/oncotarget.10094
55828-55839
Abstract  |  PDF  |  Full Text  |  How to cite

Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction

https://doi.org/10.18632/oncotarget.10095
55840-55862
Abstract  |  PDF  |  Full Text  |  How to cite

Cytoplasmic vacuolization in cell death and survival

https://doi.org/10.18632/oncotarget.10150
55863-55889
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value of amphiregulin and epiregulin mRNA expression in metastatic colorectal cancer patients

https://doi.org/10.18632/oncotarget.10151
55890-55899
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR497 expression function and clinical application in cancer

https://doi.org/10.18632/oncotarget.10152
55900-55911
Abstract  |  PDF  |  Full Text  |  How to cite

A metaanalysis of alcohol consumption and thyroid cancer risk

https://doi.org/10.18632/oncotarget.10352
55912-55923
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FGFR3TACC3 fusion in solid tumors: mini review

https://doi.org/10.18632/oncotarget.10482
55924-55938
Abstract  |  PDF  |  Full Text  |  How to cite


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