Oncotarget

VOLUME 7 (2016)

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About The Cover

The cover for issue 37 of Oncotarget features Figure 6B (Dermal fibroblasts with PDCD4 gene silencing promote formation of SCC with higher proliferative index and suppressed differentiation) from Jo, et al.

Table of Contents

Priority Research Papers

PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

https://doi.org/10.18632/oncotarget.11227
58717-58727
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heterogeneity in mechanisms of emergent resistance in pediatric Tcell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.11233
58728-58742
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6Kdependent pathways among FDAapproved compounds

https://doi.org/10.18632/oncotarget.11318
58743-58758
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy of ATR inhibitors as single agents in Ewing sarcoma

https://doi.org/10.18632/oncotarget.11643
58759-58767
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers: Immunology

Zbtb1 prevents default myeloid differentiation of lymphoidprimed multipotent progenitors

https://doi.org/10.18632/oncotarget.11356
58768-58778
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

MS4A6A genotypes are associated with the atrophy rates of Alzheimer’s disease related brain structures

https://doi.org/10.18632/oncotarget.9563
58779-58788
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer’s disease

https://doi.org/10.18632/oncotarget.11289
58789-58801
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Repetitive transcranial magnetic stimulation rTMS improves behavioral and biochemical deficits in levodopainduced dyskinetic rats model

https://doi.org/10.18632/oncotarget.11587
58802-58812
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Pathology

Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson’s disease

https://doi.org/10.18632/oncotarget.11020
58813-58831
Abstract  |  PDF  |  Full Text  |  How to cite

Boar seminal plasma exosomes maintain sperm function by infiltrating into the sperm membrane

https://doi.org/10.18632/oncotarget.11315
58832-58847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

https://doi.org/10.18632/oncotarget.11585
58848-58861
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Immunology

MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases

https://doi.org/10.18632/oncotarget.11186
58862-58875
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Neuroscience

Glutamatergic stimulation induces GluN2B translation by the nitric oxideHemeRegulated eIF2α kinase in cortical neurons

https://doi.org/10.18632/oncotarget.11417
58876-58892
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

hERG1/Kv111 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurindependent mechanism

https://doi.org/10.18632/oncotarget.3797
58893-58902
Abstract  |  PDF  |  Full Text  |  How to cite

Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma

https://doi.org/10.18632/oncotarget.10368
58903-58914
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aloeemodin inhibits HER2 expression through the downregulation of Ybox binding protein1 in HER2overexpressing human breast cancer cells

https://doi.org/10.18632/oncotarget.10410
58915-58930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulated long noncoding RNA CLMAT3 promotes the proliferation of colorectal cancer cells by targeting regulators of the cell cycle pathway

https://doi.org/10.18632/oncotarget.10431
58931-58938
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

https://doi.org/10.18632/oncotarget.10624
58939-58952
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crosstalk between osteoprotegerin OPG fatty acid synthase FASN and cycloxygenase2 COX2 in breast cancer: implications in carcinogenesis

https://doi.org/10.18632/oncotarget.9835
58953-58974
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PreImplantation factor PIF therapy provides comprehensive protection against radiation induced pathologies

https://doi.org/10.18632/oncotarget.10635
58975-58994
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Momordin Ic a new natural SENP1 inhibitor inhibits prostate cancer cell proliferation

https://doi.org/10.18632/oncotarget.10636
58995-59005
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

VAV1Cre mediated hematopoietic deletion of CBL and CBLB leads to JMMLlike aggressive earlyneonatal myeloproliferative disease

https://doi.org/10.18632/oncotarget.10638
59006-59016
Abstract  |  PDF  |  Full Text  |  How to cite

Tobacco smoking and methylation of genes related to lung cancer development

https://doi.org/10.18632/oncotarget.10007
59017-59028
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and metaanalysis

https://doi.org/10.18632/oncotarget.10665
59029-59048
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comparison of small biopsy specimens and surgical specimens for the detection of EGFR mutations and EML4ALK in nonsmallcell lung cancer

https://doi.org/10.18632/oncotarget.10011
59049-59057
Abstract  |  PDF  |  Full Text  |  How to cite

Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.10175
59058-59069
Abstract  |  PDF  |  Full Text  |  How to cite

The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA101 in renal cell carcinoma

https://doi.org/10.18632/oncotarget.10887
59070-59086
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.10824
59087-59097
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coexpression modules of NF1 PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases

https://doi.org/10.18632/oncotarget.10359
59098-59114
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Singlestrand DNA library preparation improves sequencing of formalinfixed and paraffinembedded FFPE cancer DNA

https://doi.org/10.18632/oncotarget.10827
59115-59128
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Destabilisation aggregation toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10991
59129-59143
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ βcatenin activity and enhances epithelialtomesenchymal transition through upregulation of ZEB1 SOX9 and MACC1

https://doi.org/10.18632/oncotarget.10828
59144-59157
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas

https://doi.org/10.18632/oncotarget.10993
59158-59172
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

https://doi.org/10.18632/oncotarget.10384
59173-59188
Abstract  |  PDF  |  Full Text  |  How to cite

Prediction and diagnosis of renal cell carcinoma using nuclear magnetic resonancebased serum metabolomics and selforganizing maps

https://doi.org/10.18632/oncotarget.10830
59189-59198
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of α7nicotinic acetylcholine receptor in nicotineinduced invasion and epithelialtomesenchymal transition in human nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.10498
59199-59208
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas

https://doi.org/10.18632/oncotarget.10962
59209-59219
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite  |  Press Release
Special Collection ToC

Xanthine oxidoreductase is required for genotoxic stressinduced NKG2D ligand expression and gemcitabinemediated antitumor activity

https://doi.org/10.18632/oncotarget.11042
59220-59235
Abstract  |  PDF  |  Full Text  |  How to cite

Apatinib inhibits cellular invasion and migration by fusion kinase KIF5BRET via suppressing RET/Src signaling pathway

https://doi.org/10.18632/oncotarget.10985
59236-59244
Abstract  |  PDF  |  Full Text  |  How to cite

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKTdependent positive feedback loop

https://doi.org/10.18632/oncotarget.11043
59245-59259
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CRLF2 overexpression is a poor prognostic marker in children with high risk Tcell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.10610
59260-59272
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting the RAS/MAPK pathway with miR181a in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11150
59273-59286
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR146a5p inhibits cell proliferation and cell cycle progression in NSCLC cell lines by targeting CCND1 and CCND2

https://doi.org/10.18632/oncotarget.11040
59287-59298
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5fluorodeoxyuridine through replication fork collapseinduced DNA damage

https://doi.org/10.18632/oncotarget.11151
59299-59313
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Positive nuclear BAP1 immunostaining helps differentiate nonsmall cell lung carcinomas from malignant mesothelioma

https://doi.org/10.18632/oncotarget.10653
59314-59321
Abstract  |  PDF  |  Full Text  |  How to cite
Special Collection ToC

Preclinical activity of melflufen J1 in ovarian cancer

https://doi.org/10.18632/oncotarget.11163
59322-59335
Abstract  |  PDF  |  Full Text  |  How to cite

Establishment of a large panel of patientderived preclinical models of human renal cell carcinoma

https://doi.org/10.18632/oncotarget.10659
59336-59359
Abstract  |  PDF  |  Full Text  |  How to cite

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumorinitiating cells

https://doi.org/10.18632/oncotarget.10661
59360-59376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

XB130 is overexpressed in prostate cancer and involved in cell growth and invasion

https://doi.org/10.18632/oncotarget.11074
59377-59387
Abstract  |  PDF  |  Full Text  |  How to cite

HDAC10 promotes lung cancer proliferation via AKT phosphorylation

https://doi.org/10.18632/oncotarget.10673
59388-59401
Abstract  |  PDF  |  Full Text  |  How to cite

Novel miR122 delivery system based on MS2 virus like particle surface displaying cellpenetrating peptide TAT for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10681
59402-59416
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A general strategy to optimize immunogenicity of HLAB*0702 restricted cryptic peptides from tumor associated antigens: Design of universal neoantigen like tumor vaccines for HLAB*0702 positive patients

https://doi.org/10.18632/oncotarget.11086
59417-59428
Abstract  |  PDF  |  Full Text  |  How to cite

IL1βstimulated βcatenin upregulation promotes angiogenesis in human lungderived mesenchymal stromal cells through a NFκBdependent microRNA433 induction

https://doi.org/10.18632/oncotarget.10683
59429-59440
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TIMP1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRASmutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.11118
59441-59457
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells

https://doi.org/10.18632/oncotarget.10694
59458-59470
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel antiPSMA human scFv has the potential to be used as a diagnostic tool in prostate cancer

https://doi.org/10.18632/oncotarget.10697
59471-59481
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Shortterm pyrrolidine dithiocarbamate administration attenuates cachexiainduced alterations to muscle and liver in ApcMin/+ mice

https://doi.org/10.18632/oncotarget.10699
59482-59502
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin enhances TRAILinduced apoptosis by Mcl1 degradation via Mule in colorectal cancer cells

https://doi.org/10.18632/oncotarget.11147
59503-59518
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The human box C/D snoRNAs U3 and U8 are required for prerRNA processing and tumorigenesis

https://doi.org/10.18632/oncotarget.11148
59519-59534
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett’s esophagus and can be exploited for a novel endoscopic surveillance

https://doi.org/10.18632/oncotarget.11149
59535-59547
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformin use and cervical cancer risk in female patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.10934
59548-59555
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA stabilizes the Yboxbinding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis

https://doi.org/10.18632/oncotarget.10006
59556-59571
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oleandrin induces DNA damage responses in cancer cells by suppressing the expression of Rad51

https://doi.org/10.18632/oncotarget.10726
59572-59579
Abstract  |  PDF  |  Full Text  |  How to cite

Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a metaanalysis

https://doi.org/10.18632/oncotarget.10936
59580-59588
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AgoRIPSeq identifies Polycomb repressive complex I member CBX7 as a major target of miR375 in prostate cancer progression

https://doi.org/10.18632/oncotarget.10729
59589-59603
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Large intergenic noncoding RNAROR reverses gemcitabineinduced autophagy and apoptosis in breast cancer cells

https://doi.org/10.18632/oncotarget.10730
59604-59617
Abstract  |  PDF  |  Full Text  |  How to cite

Statins dosedependently exert a chemopreventive effect against lung cancer in COPD patients: a populationbased cohort study

https://doi.org/10.18632/oncotarget.11162
59618-59629
Abstract  |  PDF  |  Full Text  |  How to cite

A nomogram composed of clinicopathologic features and preoperative serum tumor markers to predict lymph node metastasis in early gastric cancer patients

https://doi.org/10.18632/oncotarget.10732
59630-59639
Abstract  |  PDF  |  Full Text  |  How to cite

High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer

https://doi.org/10.18632/oncotarget.10746
59640-59651
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interleukin11 promotes epithelialmesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation

https://doi.org/10.18632/oncotarget.10831
59652-59663
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Plasma miR3243p and miR1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11198
59664-59675
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dysregulated long intergenic noncoding RNA modules contribute to heart failure

https://doi.org/10.18632/oncotarget.10834
59676-59690
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dihydromyricetin promotes autophagy and apoptosis through ROSSTAT3 signaling in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10836
59691-59703
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IRESdependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

https://doi.org/10.18632/oncotarget.10923
59704-59713
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR145 sensitizes breast cancer to doxorubicin by targeting multidrug resistanceassociated protein1

https://doi.org/10.18632/oncotarget.10845
59714-59726
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bortezomibinduced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation

https://doi.org/10.18632/oncotarget.10847
59727-59741
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The breast cancer susceptibilityrelated polymorphisms at the TOX3/LOC643714 locus associated with lung cancer risk in a Han Chinese population

https://doi.org/10.18632/oncotarget.10874
59742-59753
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chemoimmunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis

https://doi.org/10.18632/oncotarget.10880
59754-59765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Carcinomaassociated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells

https://doi.org/10.18632/oncotarget.11121
59766-59780
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide

https://doi.org/10.18632/oncotarget.10926
59781-59794
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Poor recognition of O6isopropyl dG by MGMT triggers double strand breakmediated cell death and micronucleus induction in FANCdeficient cells

https://doi.org/10.18632/oncotarget.10928
59795-59808
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dichloroacetate potentiates tamoxifeninduced cell death in breast cancer cells via downregulation of the epidermal growth factor receptor

https://doi.org/10.18632/oncotarget.10999
59809-59819
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Improved survival of patients with hepatocellular carcinoma and disparities by age race and socioeconomic status by decade 1983–2012

https://doi.org/10.18632/oncotarget.10930
59820-59833
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The 3′UTR signature defines a highly metastatic subgroup of triplenegative breast cancer

https://doi.org/10.18632/oncotarget.10975
59834-59844
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MZF1/Elk1 interaction domain as therapeutic target for protein kinase Cαbased triplenegative breast cancer cells

https://doi.org/10.18632/oncotarget.11337
59845-59859
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Simultaneous targeting of Eph receptors in glioblastoma

https://doi.org/10.18632/oncotarget.10978
59860-59876
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combined cell surface carbonic anhydrase 9 and CD147 antigens enable highefficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.10979
59877-59891
Abstract  |  PDF  |  Full Text  |  How to cite

Blood concentration of cyclosporine during early posttransplant period may have influence on the occurrence of chronic graft versus host disease in patients who received allogeneic hematopoietic stem cell transplantation

https://doi.org/10.18632/oncotarget.10988
59892-59901
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drugloaded nanofibrous membranes

https://doi.org/10.18632/oncotarget.10989
59902-59916
Abstract  |  PDF  |  Full Text  |  How to cite

Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation

https://doi.org/10.18632/oncotarget.10990
59917-59931
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA 10b promotes abnormal expression of the protooncogene cJun in metastatic breast cancer cells

https://doi.org/10.18632/oncotarget.11000
59932-59944
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Whether regional lymph nodes evaluation should be equally required for both right and left colon cancer

https://doi.org/10.18632/oncotarget.11007
59945-59956
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Endoplasmic reticulum stress induces secretion of highmobility group proteins and is associated with tumorinfiltrating lymphocytes in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.11010
59957-59964
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A lupus antiDNA autoantibody mediates autocatalytic targeted delivery of nanoparticles to tumors

https://doi.org/10.18632/oncotarget.11015
59965-59975
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PDL1 expression in EBVnegative diffuse large Bcell lymphoma: clinicopathologic features and prognostic implications

https://doi.org/10.18632/oncotarget.11045
59976-59986
Abstract  |  PDF  |  Full Text  |  How to cite

MALDI imaging reveals NCOA7 as a potential biomarker in oral squamous cell carcinoma arising from oral submucous fibrosis

https://doi.org/10.18632/oncotarget.11046
59987-60004
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5mediated p53 arginine methylation

https://doi.org/10.18632/oncotarget.11088
60005-60020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crosstalk between the mitochondrial fission protein Drp1 and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients

https://doi.org/10.18632/oncotarget.11047
60021-60037
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells

https://doi.org/10.18632/oncotarget.11048
60038-60052
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metabolomic analysis reveals altered metabolic pathways in a rat model of gastric carcinogenesis

https://doi.org/10.18632/oncotarget.11049
60053-60073
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of miR181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia

https://doi.org/10.18632/oncotarget.11054
60074-60086
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

https://doi.org/10.18632/oncotarget.11065
60087-60100
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Short term exvivo expansion of circulating head and neck tumour cells

https://doi.org/10.18632/oncotarget.11159
60101-60109
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and diseasefree survival in breast cancer patients

https://doi.org/10.18632/oncotarget.11076
60110-60122
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SC79 protects retinal pigment epithelium cells from UV radiation via activating AktNrf2 signaling

https://doi.org/10.18632/oncotarget.11164
60123-60132
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Glypican3 induces a mesenchymal to epithelial transition in human breast cancer cells

https://doi.org/10.18632/oncotarget.11107
60133-60154
Abstract  |  PDF  |  Full Text  |  How to cite

The miR223 host noncoding transcript linc223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA

https://doi.org/10.18632/oncotarget.11165
60155-60168
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Superior efficacy of cotreatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC

https://doi.org/10.18632/oncotarget.11109
60169-60180
Abstract  |  PDF  |  Full Text  |  How to cite

Suppression of cMyc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase2 inhibitor ABC294640

https://doi.org/10.18632/oncotarget.11112
60181-60192
Abstract  |  PDF  |  Full Text  |  How to cite

Sitespecific associations between miRNA expression and survival in colorectal cancer cases

https://doi.org/10.18632/oncotarget.11173
60193-60205
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Involvement of urokinase receptor in the crosstalk between human hematopoietic stem cells and bone marrow microenvironment

https://doi.org/10.18632/oncotarget.11115
60206-60217
Abstract  |  PDF  |  Full Text  |  How to cite

DNA aneuploidy and breast cancer: a metaanalysis of 141163 cases

https://doi.org/10.18632/oncotarget.11130
60218-60229
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine CXC motif receptor 4 and Ras homolog gene family member A signaling pathway

https://doi.org/10.18632/oncotarget.11176
60230-60244
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sensitivity to PRIMA1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

https://doi.org/10.18632/oncotarget.11197
60245-60269
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic revelation of the protective effect and mechanism of Cordycep sinensis on diethylnitrosamineinduced rat hepatocellular carcinoma with proteomics

https://doi.org/10.18632/oncotarget.11201
60270-60289
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of KLF4 promotes cell senescence through microRNA203survivinp21 pathway

https://doi.org/10.18632/oncotarget.11200
60290-60302
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11206
60303-60309
Abstract  |  PDF  |  Full Text  |  How to cite

Wnt signalling is a bidirectional vulnerability of cancer cells

https://doi.org/10.18632/oncotarget.11203
60310-60331
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.11219
60332-60347
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis

https://doi.org/10.18632/oncotarget.11254
60348-60365
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation

https://doi.org/10.18632/oncotarget.11332
60366-60382
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity

https://doi.org/10.18632/oncotarget.11039
60383-60394
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings

https://doi.org/10.18632/oncotarget.10939
60395-60406
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lin28A activates androgen receptor via regulation of cmyc and promotes malignancy of ER−/Her2+ breast cancer

https://doi.org/10.18632/oncotarget.11004
60407-60418
Abstract  |  PDF  |  Full Text  |  How to cite

Smoking secondhand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality

https://doi.org/10.18632/oncotarget.11051
60419-60431
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Radiation induces premature chromatid separation via the miR1423p/Bod1 pathway in carcinoma cells

https://doi.org/10.18632/oncotarget.11080
60432-60445
Abstract  |  PDF  |  Full Text  |  How to cite

Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice

https://doi.org/10.18632/oncotarget.11108
60446-60460
Abstract  |  PDF  |  Full Text  |  How to cite

IL2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways

https://doi.org/10.18632/oncotarget.11124
60461-60474
Abstract  |  PDF  |  Full Text  |  How to cite

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

https://doi.org/10.18632/oncotarget.11125
60475-60490
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.11134
60491-60502
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of androgenresponsive lncRNAs as diagnostic and prognostic markers for prostate cancer

https://doi.org/10.18632/oncotarget.11391
60503-60518
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

USP9X destabilizes pVHL and promotes cell proliferation

https://doi.org/10.18632/oncotarget.11139
60519-60534
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Waking up dormant tumor suppressor genes with zinc fingers TALEs and the CRISPR/dCas9 system

https://doi.org/10.18632/oncotarget.11142
60535-60554
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluation of DNMT3A genetic polymorphisms as outcome predictors in AML patients

https://doi.org/10.18632/oncotarget.11143
60555-60574
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelialmesenchymal transition and induced pluripotency of colon cancer cells

https://doi.org/10.18632/oncotarget.11169
60575-60592
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes

https://doi.org/10.18632/oncotarget.11260
60593-60608
Abstract  |  PDF  |  Full Text  |  How to cite

Activated platelets inhibit hepatocellular carcinoma cell differentiation and promote tumor progression via platelettumor cell binding

https://doi.org/10.18632/oncotarget.11300
60609-60622
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD151mediated adhesion is crucial to osteosarcoma pulmonary metastasis

https://doi.org/10.18632/oncotarget.11380
60623-60638
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Clinical significance of postsurgical residual tumor burden and radiation therapy in treating patients with lacrimal adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.10259
60639-60646
Abstract  |  PDF  |  Full Text  |  How to cite

Better pathologic complete response and relapsefree survival after carboplatin plus paclitaxel compared with epirubicin plus paclitaxel as neoadjuvant chemotherapy for locally advanced triplenegative breast cancer: a randomized phase 2 trial

https://doi.org/10.18632/oncotarget.10607
60647-60656
Abstract  |  PDF  |  Full Text  |  How to cite

Increased expression of αTubulin is associated with poor prognosis in patients with pancreatic cancer after surgical resection

https://doi.org/10.18632/oncotarget.10630
60657-60664
Abstract  |  PDF  |  Full Text  |  How to cite

Treatment of primary intracranial germ cell tumors: Single center experience with 42 clinically diagnosed cases

https://doi.org/10.18632/oncotarget.10218
60665-60675
Abstract  |  PDF  |  Full Text  |  How to cite

Leukocyte mitochondrial DNA copy number anthropometric indices and weight change in US women

https://doi.org/10.18632/oncotarget.10325
60676-60686
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Exosomes: small vesicles with big roles in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10807
60687-60697
Abstract  |  PDF  |  Full Text  |  How to cite

Microenvironment drug resistance in multiple myeloma: emerging new players

https://doi.org/10.18632/oncotarget.10849
60698-60711
Abstract  |  PDF  |  Full Text  |  How to cite

Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway

https://doi.org/10.18632/oncotarget.10858
60712-60722
Abstract  |  PDF  |  Full Text  |  How to cite

Role of microRNAs in drug resistance of multiple myeloma

https://doi.org/10.18632/oncotarget.11032
60723-60735
Abstract  |  PDF  |  Full Text  |  How to cite

The functions and clinical applications of tumorderived exosomes

https://doi.org/10.18632/oncotarget.11177
60736-60751
Abstract  |  PDF  |  Full Text  |  How to cite

Mesenchymal stromal cells MSCs and colorectal cancer: a troublesome twosome for the antitumour immune response

https://doi.org/10.18632/oncotarget.11354
60752-60774
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Perlecan/HSPG2 and matrilysin/MMP7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients

https://doi.org/10.18632/oncotarget.11976
60775-60775
Correction  |  PDF  |  How to cite


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