Oncotarget

VOLUME 7 (2016)

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About The Cover

The cover for issue 46 of Oncotarget features Figure 2, "Immunohistochemistry reveals neuroendocrine origin of tumors in LSL-MYCN;hGFAP-Cre mice", from Fielitz et al.

Table of Contents

Priority Research Papers

Characterization of pancreatic glucagonproducing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAPpositive cells

https://doi.org/10.18632/oncotarget.12766
74415-74426
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The deubiquitinase USP54 is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis

https://doi.org/10.18632/oncotarget.12769
74427-74434
Abstract  |  PDF  |  Full Text  |  How to cite

Absence of ERK5/MAPK7 delays tumorigenesis in Atm/ mice

https://doi.org/10.18632/oncotarget.12908
74435-74447
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Kinetics prognostic and predictive values of ESR1 circulating mutations in metastatic breast cancer patients progressing on aromatase inhibitor

https://doi.org/10.18632/oncotarget.12950
74448-74459
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Polymorphisms of the murine mitochondrial ND4 CYTB and COX3 genes impact hematopoiesis during aging

https://doi.org/10.18632/oncotarget.11952
74460-74472
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

7Ketocholesterol induces ATM/ATR Chk1/Chk2 PI3K/Akt signalings cytotoxicity and IL8 production in endothelial cells

https://doi.org/10.18632/oncotarget.12578
74473-74483
Abstract  |  PDF  |  Full Text  |  How to cite

Ampelopsin attenuates brain aging of Dgalinduced rats through miR34amediated SIRT1/mTOR signal pathway

https://doi.org/10.18632/oncotarget.12811
74484-74495
Abstract  |  PDF  |  Full Text  |  How to cite

Patient fibroblastsderived induced neurons demonstrate autonomous neuronal defects in adultonset Krabbe disease

https://doi.org/10.18632/oncotarget.12812
74496-74509
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Longterm exposure to air pollution is associated with biological aging

https://doi.org/10.18632/oncotarget.12903
74510-74525
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

G6PC3 ALDOA and CS induction accompanies mir122 downregulation in the mechanical asphyxia and can serve as hypoxia biomarkers

https://doi.org/10.18632/oncotarget.12931
74526-74536
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Pathology

Intravenous administration of xenogenic adiposederived mesenchymal stem cells ADMSC and ADMSCderived exosomes markedly reduced brain infarct volume and preserved neurological function in rat after acute ischemic stroke

https://doi.org/10.18632/oncotarget.12902
74537-74556
Abstract  |  PDF  |  Full Text  |  How to cite

Beauveria attenuates asthma by inhibiting inflammatory response and inducing lymphocytic cell apoptosis

https://doi.org/10.18632/oncotarget.12958
74557-74568
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

MiR185/AKT and miR29a/Collagen 1a pathways are activated in IPF BAL cells

https://doi.org/10.18632/oncotarget.12740
74569-74581
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quantitative proteomics reveals Piccolo as a candidate serological correlate of recovery from GuillainBarré syndrome

https://doi.org/10.18632/oncotarget.12789
74582-74591
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tolllike receptor agonists partially restore the production of proinflammatory cytokines and type I interferon in Sézary syndrome

https://doi.org/10.18632/oncotarget.12816
74592-74601
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells

https://doi.org/10.18632/oncotarget.12980
74602-74611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Autophagy and Cell Death

Fyn phosphorylates AMPK to inhibit AMPK activity and AMPdependent activation of autophagy

https://doi.org/10.18632/oncotarget.11916
74612-74629
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis

https://doi.org/10.18632/oncotarget.11858
74630-74647
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hyperosmotic treatment synergistically boost efficiency of cellpermeable peptides

https://doi.org/10.18632/oncotarget.9448
74648-74657
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Rapamycin ameliorates chitosan nanoparticleinduced developmental defects of preimplantation embryos in mice

https://doi.org/10.18632/oncotarget.10813
74658-74677
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic significance of heparanase expression in metastatic melanoma

https://doi.org/10.18632/oncotarget.12492
74678-74685
Abstract  |  PDF  |  Full Text  |  How to cite

Selenite promotes alltrans retinoic acidinduced maturation of acute promyelocytic leukemia cells

https://doi.org/10.18632/oncotarget.12531
74686-74700
Abstract  |  PDF  |  Full Text  |  How to cite

Specificity and biologic activities of novel antimembrane IgM antibodies

https://doi.org/10.18632/oncotarget.12506
74701-74723
Abstract  |  PDF  |  Full Text  |  How to cite

Nutlin3 inhibits androgen receptordriven cFLIP expression resulting in apoptosis of prostate cancer cells

https://doi.org/10.18632/oncotarget.12542
74724-74733
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer

https://doi.org/10.18632/oncotarget.12543
74734-74746
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells

https://doi.org/10.18632/oncotarget.12546
74747-74767
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions

https://doi.org/10.18632/oncotarget.11013
74768-74778
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exocytosis of polyubiquitinated proteins in bortezomibresistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors

https://doi.org/10.18632/oncotarget.11340
74779-74796
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm IPMN associated with disease progression

https://doi.org/10.18632/oncotarget.11501
74797-74806
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PEITCmediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells

https://doi.org/10.18632/oncotarget.11655
74807-74819
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Akt isoform specific effects in ovarian cancer progression

https://doi.org/10.18632/oncotarget.11204
74820-74833
Abstract  |  PDF  |  Full Text  |  How to cite

Dendritic cellderived nitric oxide inhibits the differentiation of effector dendritic cells

https://doi.org/10.18632/oncotarget.11361
74834-74845
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Detection of cellular senescence within human invasive breast carcinomas distinguishes different breast tumor subtypes

https://doi.org/10.18632/oncotarget.12432
74846-74859
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems

https://doi.org/10.18632/oncotarget.11382
74860-74871
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Kindlin2 interacts with βcatenin and YB1 to enhance EGFR transcription during glioma progression

https://doi.org/10.18632/oncotarget.12439
74872-74885
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Neutrophilia in locally advanced cervical cancer: A novel biomarker for imageguided adaptive brachytherapy

https://doi.org/10.18632/oncotarget.12440
74886-74894
Abstract  |  PDF  |  Full Text  |  How to cite

A three ion channel genesbased signature predicts prognosis of primary glioblastoma patients and reveals a chemotherapy sensitive subtype

https://doi.org/10.18632/oncotarget.12462
74895-74903
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of tumor infiltrating NK cells and macrophages in stage II+III esophageal cancer patients

https://doi.org/10.18632/oncotarget.12484
74904-74916
Abstract  |  PDF  |  Full Text  |  How to cite

Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells

https://doi.org/10.18632/oncotarget.12493
74917-74930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A signaling cascade including ARID1A GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment

https://doi.org/10.18632/oncotarget.11647
74931-74946
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of the zinc finger 216 ZNF216 in human carcinoma cells: a potential regulator of EGFR activity

https://doi.org/10.18632/oncotarget.12509
74947-74965
Abstract  |  PDF  |  Full Text  |  How to cite

Periostin is identified as a putative metastatic marker in breast cancerderived exosomes

https://doi.org/10.18632/oncotarget.11663
74966-74978
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

APOBEC3 deletion increases the risk of breast cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.11792
74979-74986
Abstract  |  PDF  |  Full Text  |  How to cite

Antihepatocellular carcinoma properties of the antialcoholism drug disulfiram discovered to enzymatically inhibit the AMPKrelated kinase SNARK in vitro

https://doi.org/10.18632/oncotarget.11820
74987-74999
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

nc886 a noncoding RNA and suppressor of PKR exerts an oncogenic function in thyroid cancer

https://doi.org/10.18632/oncotarget.11852
75000-75012
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interleukin6 and Creactive protein as prognostic biomarkers in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.12601
75013-75022
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SMYD3mediated lysine methylation in the PH domain is critical for activation of AKT1

https://doi.org/10.18632/oncotarget.11898
75023-75037
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR8855p suppresses hepatocellular carcinoma metastasis and inhibits Wnt/βcatenin signaling pathway

https://doi.org/10.18632/oncotarget.12602
75038-75051
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of sulfatase1 in murine hepatocarcinoma HcaF cell line downregulates mesothelin and leads to reduction in lymphatic metastasis both in vitro and in vivo

https://doi.org/10.18632/oncotarget.11933
75052-75063
Abstract  |  PDF  |  Full Text  |  How to cite

Porcine epidemic diarrhea virus nucleoprotein contributes to HMGB1 transcription and release by interacting with C/EBPβ

https://doi.org/10.18632/oncotarget.11991
75064-75080
Abstract  |  PDF  |  Full Text  |  How to cite

The antifibrotic effect of GV1001 combined with gemcitabine on treatment of pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.12057
75081-75093
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The clinicopathologic relevance and prognostic value of tumor deposits and the applicability of N1c category in rectal cancer with preoperative radiotherapy

https://doi.org/10.18632/oncotarget.12058
75094-75103
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of small molecule inhibitors of ERCC1XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells

https://doi.org/10.18632/oncotarget.12072
75104-75117
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR1395p reverses CD44+/CD133+associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells

https://doi.org/10.18632/oncotarget.12611
75118-75129
Abstract  |  PDF  |  Full Text  |  How to cite

CD103+ intraepithelial T cells in highgrade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

https://doi.org/10.18632/oncotarget.12077
75130-75144
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Efficacy of crizotinib and pemetrexedbased chemotherapy in Chinese NSCLC patients with ROS1 rearrangement

https://doi.org/10.18632/oncotarget.12612
75145-75154
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Apoptosis signalregulating kinase 1 exhibits oncogenic activity in pancreatic cancer

https://doi.org/10.18632/oncotarget.12090
75155-75164
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXRmiR22CCNA2 signaling pathway

https://doi.org/10.18632/oncotarget.12614
75165-75175
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic characterization of highrisk nonmuscle invasive bladder cancer

https://doi.org/10.18632/oncotarget.12661
75176-75184
Abstract  |  PDF  |  Full Text  |  How to cite

miR4245p promotes proliferation of gastric cancer by targeting Smad3 through TGFβ signaling pathway

https://doi.org/10.18632/oncotarget.12092
75185-75196
Abstract  |  PDF  |  Full Text  |  How to cite

Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair

https://doi.org/10.18632/oncotarget.12113
75197-75209
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Protein tyrosine phosphatase PTP4A1 promotes proliferation and epithelialmesenchymal transition in intrahepatic cholangiocarcinoma via the PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.12116
75210-75220
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum depletion induced cancer stem celllike phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells

https://doi.org/10.18632/oncotarget.12117
75221-75234
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Somatic polyploidy is associated with the upregulation of cMYC interacting genes and EMTlike signature

https://doi.org/10.18632/oncotarget.12118
75235-75260
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas

https://doi.org/10.18632/oncotarget.12127
75261-75272
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IMPA2 polymorphisms and risk of ischemic stroke in a northwest Han Chinese population

https://doi.org/10.18632/oncotarget.12133
75273-75278
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Highthroughput proteomics integrated with gene microarray for discovery of colorectal cancer potential biomarkers

https://doi.org/10.18632/oncotarget.12143
75279-75292
Abstract  |  PDF  |  Full Text  |  How to cite

Induction of antiEGFR immune response with mimotopes identified from a phage display peptide library by panitumumab

https://doi.org/10.18632/oncotarget.12167
75293-75306
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.12171
75307-75318
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumorspecific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase

https://doi.org/10.18632/oncotarget.12173
75319-75327
Abstract  |  PDF  |  Full Text  |  How to cite

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53

https://doi.org/10.18632/oncotarget.12175
75328-75338
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization

https://doi.org/10.18632/oncotarget.12180
75339-75352
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Concentration of circulating miRNAcontaining particles in serum enhances miRNA detection and reflects CRC tissuerelated deregulations

https://doi.org/10.18632/oncotarget.12205
75353-75365
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells

https://doi.org/10.18632/oncotarget.12207
75366-75378
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Methylation of RAD51B XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck lung and cervix

https://doi.org/10.18632/oncotarget.12211
75379-75393
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fragile X mental retardation protein promotes astrocytoma proliferation via the MEK/ERK signaling pathway

https://doi.org/10.18632/oncotarget.12215
75394-75406
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Indoleamine 23dioxygenase regulates antitumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment

https://doi.org/10.18632/oncotarget.12249
75407-75424
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting SALL4 by entinostat in lung cancer

https://doi.org/10.18632/oncotarget.12251
75425-75440
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TACC3 overexpression in cholangiocarcinoma correlates with poor prognosis and is a potential anticancer molecular drug target for HDAC inhibitors

https://doi.org/10.18632/oncotarget.12254
75441-75456
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The precision relationships between eight GWASidentified genetic variants and breast cancer in a Chinese population

https://doi.org/10.18632/oncotarget.12255
75457-75467
Abstract  |  PDF  |  Full Text  |  How to cite

Tyrosine kinase LYN is an oncotarget in human cervical cancer: A quantitative proteomic based study

https://doi.org/10.18632/oncotarget.12258
75468-75481
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secondline ramucirumab therapy for advanced hepatocellular carcinoma REACH: an East Asian and nonEast Asian subgroup analysis

https://doi.org/10.18632/oncotarget.12780
75482-75491
Abstract  |  PDF  |  Full Text  |  How to cite

Should all breast cancer patients with four or more positive lymph nodes who underwent modified radical mastectomy be treated with postoperative radiotherapy A populationbased study

https://doi.org/10.18632/oncotarget.12260
75492-75502
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epithelioid peritoneal mesothelioma: a hybrid phenotype within a mesenchymalepithelial/epithelialmesenchymal transition framework

https://doi.org/10.18632/oncotarget.12262
75503-75517
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The impact of ERBBfamily germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2positive breast cancer

https://doi.org/10.18632/oncotarget.12782
75518-75525
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extrachromosomal HPV16 LCR transcriptional activation by HDACi opposed by cellular differentiation and DNA integration

https://doi.org/10.18632/oncotarget.12263
75526-75538
Abstract  |  PDF  |  Full Text  |  How to cite

An inhibitor of cholesterol absorption displays antimyeloma activity by targeting the JAK2STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.12265
75539-75550
Abstract  |  PDF  |  Full Text  |  How to cite

PARP1 inhibitor olaparib Lynparza exerts synthetic lethal effect against ligase 4deficient melanomas

https://doi.org/10.18632/oncotarget.12270
75551-75560
Abstract  |  PDF  |  Full Text  |  How to cite

SMAD7 polymorphisms and colorectal cancer risk: a metaanalysis of casecontrol studies

https://doi.org/10.18632/oncotarget.12285
75561-75570
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL1 drives breast cancer growth and bone metastasis in vivo

https://doi.org/10.18632/oncotarget.12289
75571-75584
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

cMYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castrationresistant prostate cancer

https://doi.org/10.18632/oncotarget.12310
75585-75602
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts

https://doi.org/10.18632/oncotarget.12312
75603-75615
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interconnections between apoptotic and autophagic pathways during thiopurineinduced toxicity in cancer cells: the role of reactive oxygen species

https://doi.org/10.18632/oncotarget.12313
75616-75634
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Fluorescenceguided surgery of a highlymetastatic variant of human triplenegative breast cancer targeted with a cancerspecific GFP adenovirus prevents recurrence

https://doi.org/10.18632/oncotarget.12314
75635-75647
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wholeexome sequencing of muscleinvasive bladder cancer identifies recurrent copy number variation in IPO11 and prognostic significance of importin11 overexpression on poor survival

https://doi.org/10.18632/oncotarget.12315
75648-75658
Abstract  |  PDF  |  Full Text  |  How to cite

Curcumin targets the TFEBlysosome pathway for induction of autophagy

https://doi.org/10.18632/oncotarget.12318
75659-75671
Abstract  |  PDF  |  Full Text  |  How to cite

Epithelial cells captured from ductal carcinoma in situ reveal a gene expression signature associated with progression to invasive breast cancer

https://doi.org/10.18632/oncotarget.12352
75672-75684
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential effects of peptidoglycan on colorectal tumors and intestinal tissue postpelvic radiotherapy

https://doi.org/10.18632/oncotarget.12353
75685-75697
Abstract  |  PDF  |  Full Text  |  How to cite

SIRT1mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcomaassociated herpesvirus transformed cells

https://doi.org/10.18632/oncotarget.12359
75698-75711
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deregulation of the pRbE2F4 axis alters epidermal homeostasis and favors tumor development

https://doi.org/10.18632/oncotarget.12362
75712-75728
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FOXC1 identifies basallike breast cancer in a hereditary breast cancer cohort

https://doi.org/10.18632/oncotarget.12370
75729-75738
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of AMPK in human malignancies: A metaanalysis

https://doi.org/10.18632/oncotarget.12405
75739-75748
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.12407
75749-75762
Abstract  |  PDF  |  Full Text  |  How to cite

Hypoxiainduced CCL28 promotes recruitment of regulatory T cells and tumor growth in liver cancer

https://doi.org/10.18632/oncotarget.12409
75763-75773
Abstract  |  PDF  |  Full Text  |  How to cite

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death

https://doi.org/10.18632/oncotarget.12411
75774-75789
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lumbar punctureadministered resveratrol inhibits STAT3 activation enhancing autophagy and apoptosis in orthotopic rat glioblastomas

https://doi.org/10.18632/oncotarget.12414
75790-75799
Abstract  |  PDF  |  Full Text  |  How to cite

Secretory leukoprotease inhibitor is required for efficient quercetinmediated suppression of TNFα secretion

https://doi.org/10.18632/oncotarget.12415
75800-75809
Abstract  |  PDF  |  Full Text  |  How to cite

Exploring the interactions of the RAS family in the human protein network and their potential implications in RASdirected therapies

https://doi.org/10.18632/oncotarget.12416
75810-75826
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PITX2 and PANCR DNA methylation predicts overall survival in patients with head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12417
75827-75838
Abstract  |  PDF  |  Full Text  |  How to cite

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

https://doi.org/10.18632/oncotarget.12419
75839-75853
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ran GTPase promotes cancer progression via Met receptormediated downstream signaling

https://doi.org/10.18632/oncotarget.12420
75854-75864
Abstract  |  PDF  |  Full Text  |  How to cite

MiR608 premiR1241 and premiR26a1 polymorphisms modify susceptibility and recurrencefree survival in surgically resected CRC individuals

https://doi.org/10.18632/oncotarget.12422
75865-75873
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells

https://doi.org/10.18632/oncotarget.12425
75874-75901
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human betadefensin 3 contributes to the carcinogenesis of cervical cancer via activation of NFκB signaling

https://doi.org/10.18632/oncotarget.12426
75902-75913
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secondgeneration proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicininduced apoptosis

https://doi.org/10.18632/oncotarget.12427
75914-75925
Abstract  |  PDF  |  Full Text  |  How to cite

Delayed reendothelialization with rapamycin is rescued by the addition of nicorandil in ballooninjured rat carotid arteries

https://doi.org/10.18632/oncotarget.12444
75926-75939
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cancer cellbinding peptide fused Fc domain activates immune effector cells and blocks tumor growth

https://doi.org/10.18632/oncotarget.12445
75940-75953
Abstract  |  PDF  |  Full Text  |  How to cite

Doxycycline is an NFκB inhibitor that induces apoptotic cell death in malignant Tcells

https://doi.org/10.18632/oncotarget.12488
75954-75967
Abstract  |  PDF  |  Full Text  |  How to cite

Phosphoproteomics reveals ALK promote cell progress via RAS/ JNK pathway in neuroblastoma

https://doi.org/10.18632/oncotarget.12513
75968-75980
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

p53 increase mitochondrial copy number via upregulation of mitochondrial transcription factor A in colorectal cancer

https://doi.org/10.18632/oncotarget.12514
75981-75995
Abstract  |  PDF  |  Full Text  |  How to cite

The prognostic value of DNA damage level in peripheral blood lymphocytes of chemotherapynaïve patients with germ cell cancer

https://doi.org/10.18632/oncotarget.12515
75996-76005
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autocrine interleukin23 promotes selfrenewal of CD133+ ovarian cancer stemlike cells

https://doi.org/10.18632/oncotarget.12579
76006-76020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Common polymorphisms in CD44 gene and susceptibility to cancer: a systematic review and metaanalysis of 45 studies

https://doi.org/10.18632/oncotarget.12580
76021-76035
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SOX17 is a tumor suppressor in endometrial cancer

https://doi.org/10.18632/oncotarget.12582
76036-76046
Abstract  |  PDF  |  Full Text  |  How to cite

Loss of UHRF2 expression is associated with human neoplasia promoter hypermethylation decreased 5hydroxymethylcytosine and high proliferative activity

https://doi.org/10.18632/oncotarget.12583
76047-76061
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12584
76062-76075
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer

https://doi.org/10.18632/oncotarget.12589
76076-76086
Abstract  |  PDF  |  Full Text  |  How to cite

Interleukin1 blockade overcomes erlotinib resistance in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12590
76087-76100
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic variants in PTPRD and risk of gestational diabetes mellitus

https://doi.org/10.18632/oncotarget.12599
76101-76107
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of ZNF703 facilitates tumorigenesis and predicts unfavorable prognosis in patients with cholangiocarcinoma

https://doi.org/10.18632/oncotarget.12627
76108-76117
Abstract  |  PDF  |  Full Text  |  How to cite

Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma

https://doi.org/10.18632/oncotarget.12660
76118-76124
Abstract  |  PDF  |  Full Text  |  How to cite

Epithelialtomesenchymal transition leads to diseasestage differences in circulating tumor cell detection and metastasis in preclinical models of prostate cancer

https://doi.org/10.18632/oncotarget.12682
76125-76139
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy

https://doi.org/10.18632/oncotarget.12683
76140-76150
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of CK19 is an independent predictor of negative outcome for patients with squamous cell carcinoma of the tongue

https://doi.org/10.18632/oncotarget.12691
76151-76158
Abstract  |  PDF  |  Full Text  |  How to cite

Visualization of early prostatic adenocarcinoma as a stem cell disease

https://doi.org/10.18632/oncotarget.12709
76159-76168
Abstract  |  PDF  |  Full Text  |  How to cite

Microarray analysis on the lncRNA expression profile in male hepatocelluar carcinoma patients with chronic hepatitis B virus infection

https://doi.org/10.18632/oncotarget.12732
76169-76180
Abstract  |  PDF  |  Full Text  |  How to cite

Combination effect of therapies targeting the PI3K and ARsignaling pathways in prostate cancer

https://doi.org/10.18632/oncotarget.12771
76181-76196
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection

https://doi.org/10.18632/oncotarget.12772
76197-76213
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of vascular mimicry in patients with urothelial carcinoma of the bladder after radical cystectomy

https://doi.org/10.18632/oncotarget.12775
76214-76223
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Focal adhesion molecule Kindlin1 mediates activation of TGFβ signaling by interacting with TGFβRI SARA and Smad3 in colorectal cancer cells

https://doi.org/10.18632/oncotarget.12779
76224-76237
Abstract  |  PDF  |  Full Text  |  How to cite

Resistance of glioma cells to nutrientdeprived microenvironment can be enhanced by CD133mediated autophagy

https://doi.org/10.18632/oncotarget.12803
76238-76249
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum exosomal miR47723p is a predictor of tumor recurrence in stage II and III colon cancer

https://doi.org/10.18632/oncotarget.12841
76250-76260
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A new classification of lymph node metastases according to the lymph node stations for predicting prognosis in surgical patients with esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12842
76261-76273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Clinical relevance of circulating mucosalassociated invariant T cell levels and their anticancer activity in patients with mucosalassociated cancer

https://doi.org/10.18632/oncotarget.11187
76274-76290
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical characteristics and prognostic factors of brain central neurocytoma

https://doi.org/10.18632/oncotarget.11228
76291-76297
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy of preoperative chemotherapy regimens in patients with initially unresectable locally advanced gastric adenocarcinoma: capecitabine and oxaliplatin XELOX or with epirubicin EOX

https://doi.org/10.18632/oncotarget.11818
76298-76307
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Laparoscopic sleeve gastrectomy versus RouxenY gastric bypass for morbid obesity: a 1:1 matched cohort study in a Chinese population

https://doi.org/10.18632/oncotarget.12536
76308-76315
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of efficacy in adjuvant chemotherapy regimens in patients with radically resected gastric cancer: a propensitymatched analysis

https://doi.org/10.18632/oncotarget.11783
76316-76326
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

TMPRSS4 as an emerging potential poor prognostic factor for solid tumors: A systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.10153
76327-76336
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting signal transduction pathways of cancer stem cells for therapeutic opportunities of metastasis

https://doi.org/10.18632/oncotarget.10942
76337-76353
Abstract  |  PDF  |  Full Text  |  How to cite


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