VOLUME 7 (2016)
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Molecular signatures of age-associated chronic degeneration of shoulder muscles. See Raz et al.
Table of Contents
Research Perspectives
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| Integrative microRNA and gene profiling data analysis reveals novel biomarkers and mechanisms for lung cancer |
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https://doi.org/10.18632/oncotarget.7264
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| 8441-8454 |
Research Perspectives: Neuroscience
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| Acute stress enhances the expression of neuroprotection and neurogenesisassociated genes in the hippocampus of a mouse restraint model |
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https://doi.org/10.18632/oncotarget.7225
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| 8455-8465 |
Research Papers: Gerotarget (Focus on Aging)
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| Age and brain regiondependent αsynuclein oligomerization is attributed to alterations in intrinsic enzymes regulating αsynuclein phosphorylation in aging monkey brains |
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https://doi.org/10.18632/oncotarget.6445
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| 8466-8480 |
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| Potential role of PCTAIRE2 PCTAIRE3 and PHistone H4 in amyloid precursor proteindependent Alzheimer pathology |
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https://doi.org/10.18632/oncotarget.7380
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| 8481-8497 |
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| Moderate treadmill running exercise prior to tendon injury enhances wound healing in aging rats |
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https://doi.org/10.18632/oncotarget.7381
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| 8498-8512 |
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| Molecular signatures of ageassociated chronic degeneration of shoulder muscles |
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https://doi.org/10.18632/oncotarget.7382
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| 8513-8523 |
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| Epigenetic clock analyses of cellular senescence and ageing |
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https://doi.org/10.18632/oncotarget.7383
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| 8524-8531 |
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| Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of agerelated macular degeneration |
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https://doi.org/10.18632/oncotarget.7384
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| 8532-8545 |
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| Highlighting the impact of aging on type I collagen: labelfree investigation using confocal reflectance microscopy and diffuse reflectance spectroscopy in 3D matrix model |
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https://doi.org/10.18632/oncotarget.7385
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| 8546-8555 |
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| Investigating the specific core geneticandepigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells |
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https://doi.org/10.18632/oncotarget.7388
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| 8556-8579 |
Research Papers: Pathology
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| Integrative analysis of genomewide association studies and gene expression analysis identifies pathways associated with rheumatoid arthritis |
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https://doi.org/10.18632/oncotarget.7390
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| 8580-8589 |
Research Papers: Immunology
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| GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis |
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https://doi.org/10.18632/oncotarget.6535
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| 8590-8600 |
Reviews
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| Molecular mechanisms of long noncoding RNAs on gastric cancer |
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https://doi.org/10.18632/oncotarget.6926
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| 8601-8612 |
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| The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease |
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https://doi.org/10.18632/oncotarget.6937
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| 8613-8624 |
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| Evolving roles of circadian rhythms in liver homeostasis and pathology |
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https://doi.org/10.18632/oncotarget.7065
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| 8625-8639 |
Research Papers
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| Irsogladine maleate a gastric mucosal protectant suppresses intestinal polyp development in Apcmutant mice |
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https://doi.org/10.18632/oncotarget.7082
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| 8640-8652 |
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| Small molecule screen for inhibitors of expression from canonical CREB response elementcontaining promoters |
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https://doi.org/10.18632/oncotarget.7085
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| 8653-8662 |
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| The long noncoding RNA MALAT1 promotes tumordriven angiogenesis by upregulating proangiogenic gene expression |
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https://doi.org/10.18632/oncotarget.6675
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| 8663-8675 |
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| Hyperactive ERK and persistent mTOR signaling characterize vemurafenib resistance in papillary thyroid cancer cells |
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https://doi.org/10.18632/oncotarget.6779
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| 8676-8687 |
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| Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine Nacetyltransferasedependent acetylation and bioactivation of aromatic amine carcinogens |
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https://doi.org/10.18632/oncotarget.7086
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| 8688-8699 |
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| Pololike kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloidinduced apoptosis |
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https://doi.org/10.18632/oncotarget.3901
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| 8700-8711 |
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| <i>TERT</i> promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas |
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https://doi.org/10.18632/oncotarget.6007
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| 8712-8725 |
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| MicroRNAs 125a and 125b inhibit ovarian cancer cells through posttranscriptional inactivation of EIF4EBP1 |
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https://doi.org/10.18632/oncotarget.6474
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| 8726-8742 |
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| An individualized prognostic signature for gastric cancer patients treated with 5Fluorouracilbased chemotherapy and distinct multiomics characteristics of prognostic groups |
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https://doi.org/10.18632/oncotarget.7087
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| 8743-8755 |
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| Overexpression of miR199a5p decreases esophageal cancer cell proliferation through repression of mitogenactivated protein kinase kinase kinase11 MAP3K11 |
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https://doi.org/10.18632/oncotarget.6752
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| 8756-8770 |
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| Tumor sialylation impedes T cell mediated antitumor responses while promoting tumor associatedregulatory T cells |
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https://doi.org/10.18632/oncotarget.6822
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| 8771-8782 |
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| microRNA1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis |
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https://doi.org/10.18632/oncotarget.7088
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| 8783-8796 |
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| Oblongifolin M an active compound isolated from a Chinese medical herb Garcinia oblongifolia potently inhibits enterovirus 71 reproduction through downregulation of ERp57 |
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https://doi.org/10.18632/oncotarget.7122
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| 8797-8808 |
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| TGFβ/Smad3 signalling regulates the transition of bone marrowderived macrophages into myofibroblasts during tissue fibrosis |
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https://doi.org/10.18632/oncotarget.6604
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| 8809-8822 |
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| Epithelial but not stromal expression of collagen alpha1III is a diagnostic and prognostic indicator of colorectal carcinoma |
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https://doi.org/10.18632/oncotarget.6815
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| 8823-8838 |
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| Prostate extracellular vesicles in patient plasma as a liquid biopsy platform for prostate cancer using nanoscale flow cytometry |
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https://doi.org/10.18632/oncotarget.6983
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| 8839-8849 |
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| NogoB receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein |
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https://doi.org/10.18632/oncotarget.7091
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| 8850-8865 |
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| Activated hepatic stellate cells promote liver cancer by induction of myeloidderived suppressor cells through cyclooxygenase2 |
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https://doi.org/10.18632/oncotarget.6839
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| 8866-8878 |
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| Generation of functional hepatocytes from human spermatogonial stem cells |
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https://doi.org/10.18632/oncotarget.7092
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| 8879-8895 |
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| Bufalin enhances antitumor effect of paclitaxel on cervical tumorigenesis via inhibiting the integrin α2/β5/FAK signaling pathway |
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https://doi.org/10.18632/oncotarget.6840
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| 8896-8907 |
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| Chromosomal anomalies at 1q 3 16q and mutations of <em>SIX1</em> and <em>DROSHA</em> genes underlie Wilms tumor recurrences |
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https://doi.org/10.18632/oncotarget.6950
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| 8908-8915 |
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| Gene 33/Mig6 inhibits hexavalent chromiuminduced DNA damage and cell transformation in human lung epithelial cells |
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https://doi.org/10.18632/oncotarget.6866
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| 8916-8930 |
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| Tristetraprolin suppresses the EMT through the downregulation of Twist1 and Snail1 in cancer cells |
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https://doi.org/10.18632/oncotarget.7094
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| 8931-8943 |
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| Expression of programmed cell deathligand 1 and its correlation with clinical outcomes in gliomas |
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https://doi.org/10.18632/oncotarget.6884
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| 8944-8955 |
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| Adenovirusmediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy |
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https://doi.org/10.18632/oncotarget.6909
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| 8956-8967 |
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| Development of a metabolites risk score for oneyear mortality risk prediction in pancreatic adenocarcinoma patients |
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https://doi.org/10.18632/oncotarget.7108
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| 8968-8978 |
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| Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression |
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https://doi.org/10.18632/oncotarget.6924
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| 8979-8992 |
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| Preclinical evaluation of a nanoformulated antihelminthic niclosamide in ovarian cancer |
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https://doi.org/10.18632/oncotarget.7113
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| 8993-9006 |
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| High level of αBcrystallin contributes to the progression of osteosarcoma |
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https://doi.org/10.18632/oncotarget.6928
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| 9007-9016 |
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| EGFRactivating mutations DNA copy number abundance of ErbB family and prognosis in lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.7029
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| 9017-9025 |
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| Parthenolide induces MITFM downregulation and senescence in patientderived MITFM<sup>high</sup> melanoma cell populations |
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https://doi.org/10.18632/oncotarget.7030
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| 9026-9040 |
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| Medical Machiavellianism: the tradeoff between benefit and harm with targeted chemotherapy |
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https://doi.org/10.18632/oncotarget.6984
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| 9041-9045 |
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| Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells |
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https://doi.org/10.18632/oncotarget.7031
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| 9046-9059 |
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| Common and distinct features of mammary tumors driven by Ptendeletion or activating Pik3ca mutation |
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https://doi.org/10.18632/oncotarget.6985
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| 9060-9068 |
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| CDK9 inhibitors selectively target estrogen receptorpositive breast cancer cells through combined inhibition of <em>MYB</em> and <em>MCL1</em> expression |
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https://doi.org/10.18632/oncotarget.6997
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| 9069-9083 |
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| Splicing factor mutations predict poor prognosis in patients with <em>de novo</em> acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.7000
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| 9084-9101 |
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| High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model |
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https://doi.org/10.18632/oncotarget.6933
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| 9102-9117 |
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| MIIP accelerates epidermal growth factor receptor protein turnover and attenuates proliferation in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.7001
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| 9118-9134 |
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| Lapatinib inhibits CIP2A/PP2A/pAkt signaling and induces apoptosis in triple negative breast cancer cells |
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https://doi.org/10.18632/oncotarget.7035
|
| 9135-9149 |
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| Exo70 is transcriptionally upregulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells |
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https://doi.org/10.18632/oncotarget.7133
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| 9150-9162 |
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| Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma |
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https://doi.org/10.18632/oncotarget.7036
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| 9163-9174 |
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| Cold inducible RNA binding protein upregulation in pituitary corticotroph adenoma induces corticotroph cell proliferation via Erk signaling pathway |
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https://doi.org/10.18632/oncotarget.7037
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| 9175-9187 |
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| BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells |
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https://doi.org/10.18632/oncotarget.6942
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| 9188-9221 |
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| MiR129 triggers autophagic flux by regulating a novel Notch1/ E2F7/Beclin1 axis to impair the viability of human malignant glioma cells |
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https://doi.org/10.18632/oncotarget.7003
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| 9222-9235 |
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| The correlation between microRNA4903p and TGFα in endometrial carcinoma tumorigenesis and progression |
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https://doi.org/10.18632/oncotarget.7061
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| 9236-9249 |
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| <em>In vitro</em> and <em>in vivo</em> inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO GDC0449 or GLI GANT61 inhibitors |
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https://doi.org/10.18632/oncotarget.7062
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| 9250-9270 |
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| MicroRNA497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle survival and vascular permeability genes |
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https://doi.org/10.18632/oncotarget.7005
|
| 9271-9287 |
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| [<sup>68</sup>Ga]PentixaforPET/CT for imaging of chemokine receptor 4 expression in small cell lung cancer initial experience |
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https://doi.org/10.18632/oncotarget.7063
|
| 9288-9295 |
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| A novel small molecule agent displays potent antimyeloma activity by inhibiting the JAK2STAT3 signaling pathway |
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https://doi.org/10.18632/oncotarget.6974
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| 9296-9308 |
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| Does bevacizumab impact antiEGFR therapy efficacy in metastatic colorectal cancer |
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https://doi.org/10.18632/oncotarget.7008
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| 9309-9321 |
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| Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating <i>VEGF</i> via PPAR responsive elements of the promoter |
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https://doi.org/10.18632/oncotarget.6975
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| 9322-9339 |
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| Altered Hepa16 cells by dimethyl sulfoxide DMSOtreatment induce antitumor immunity <em>in vivo</em> |
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https://doi.org/10.18632/oncotarget.7009
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| 9340-9352 |
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| Paracrine effect of GTP cyclohydrolase and angiopoietin1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth |
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https://doi.org/10.18632/oncotarget.6981
|
| 9353-9367 |
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| miR143 or miR145 overexpression increases cetuximabmediated antibodydependent cellular cytotoxicity in human colon cancer cells |
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https://doi.org/10.18632/oncotarget.7010
|
| 9368-9387 |
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| A 20Sprotopanoxadiol derivative overcomes multidrug resistance by antagonizing ATPbinding cassette subfamily B member 1 transporter function |
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https://doi.org/10.18632/oncotarget.7011
|
| 9388-9403 |
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| Identifying anticancer drug response related genes using an integrative analysis of transcriptomic and genomic variations with cell linebased drug perturbations |
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https://doi.org/10.18632/oncotarget.7012
|
| 9404-9419 |
|
| PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population |
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https://doi.org/10.18632/oncotarget.7137
|
| 9420-9428 |
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| A novel smallmolecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.6990
|
| 9429-9447 |
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| HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA100 |
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https://doi.org/10.18632/oncotarget.7021
|
| 9448-9461 |
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| Physalin A exerts antitumor activity in nonsmall cell lung cancer cell lines by suppressing JAK/STAT3 signaling |
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https://doi.org/10.18632/oncotarget.7051
|
| 9462-9476 |
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| Inactivation of <em>BRCA2</em> in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptormediated apoptosis |
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https://doi.org/10.18632/oncotarget.7053
|
| 9477-9490 |
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| High level of BRD4 promotes nonsmall cell lung cancer progression |
|
https://doi.org/10.18632/oncotarget.7068
|
| 9491-9500 |
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| Dehydropeptidase 1 promotes metastasis through regulation of Ecadherin expression in colon cancer |
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https://doi.org/10.18632/oncotarget.7033
|
| 9501-9512 |
|
| Depletion of CABYRa/b sensitizes lung cancer cells to TRAILinduced apoptosis through YAP/p73mediated DR5 upregulation |
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https://doi.org/10.18632/oncotarget.7069
|
| 9513-9524 |
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| The Notch pathway promotes the cancer stem cell characteristics of CD90<sup>+</sup> cells in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6672
|
| 9525-9537 |
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| The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint |
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https://doi.org/10.18632/oncotarget.7070
|
| 9538-9549 |
|
| A TET2 rs3733609 C/T genotype is associated with predisposition to the myeloproliferative neoplasms harboring JAK2V617F and confers a proliferative potential on erythroid lineages |
|
https://doi.org/10.18632/oncotarget.7072
|
| 9550-9560 |
|
| Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2overexpressing cancer cells |
|
https://doi.org/10.18632/oncotarget.7076
|
| 9561-9575 |
|
| Risk stratification based on change in plasma EpsteinBarr virus DNA load after treatment in nasopharyngeal carcinoma |
|
https://doi.org/10.18632/oncotarget.7083
|
| 9576-9585 |
|
| Polycomb complex protein BMI1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling an <i>ex vivo</i> <i>in vitro</i> and <i>in vivo</i> study |
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https://doi.org/10.18632/oncotarget.7078
|
| 9586-9599 |
Clinical Research Papers
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| Prevalence and spectrum of <em>BRCA</em> germline variants in mainland Chinese familial breast and ovarian cancer patients |
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https://doi.org/10.18632/oncotarget.7144
|
| 9600-9612 |
Case Reports
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| Nasal NK/T cell lymphoma presents with longterm nasal blockage and fever: a rare case report and literature review |
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https://doi.org/10.18632/oncotarget.7386
|
| 9613-9617 |
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