Oncotarget

VOLUME 8 (2017)

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About The Cover

The cover for issue 13 of Oncotarget features Figure 7A, "H&E analysis and the combined antitumor effects of a rat anti-mPD-L1 antibody +/- NHS-muIL12 on intravesical bladder tumors," from Fallon, et al.

Table of Contents

News

TNBC invasion: downstream of STAT3

https://doi.org/10.18632/oncotarget.15259
20517-20518
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uPAR directedimaging of headandneck cancer

https://doi.org/10.18632/oncotarget.16240
20519-20520
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HSP90 proteins in the scenario of tumor complexity

https://doi.org/10.18632/oncotarget.16266
20521-20522
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Unwanted acquired mutations in Ba/F3 transformation assays

https://doi.org/10.18632/oncotarget.16268
20523-20524
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Priority Research Papers

Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells

https://doi.org/10.18632/oncotarget.15656
20525-20542
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis

https://doi.org/10.18632/oncotarget.16129
20543-20557
Abstract  |  PDF  |  Full Text  |  How to cite

Enhanced antitumor effects by combining an IL12/antiDNA fusion protein with avelumab an antiPDL1 antibody

https://doi.org/10.18632/oncotarget.16137
20558-20571
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

https://doi.org/10.18632/oncotarget.16244
20572-20587
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells

https://doi.org/10.18632/oncotarget.15246
20588-20601
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse

https://doi.org/10.18632/oncotarget.15292
20602-20611
Abstract  |  PDF  |  Full Text  |  How to cite

Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldestold

https://doi.org/10.18632/oncotarget.15296
20612-20621
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Pathology

Fibrinogen is related to longterm mortality in Chinese patients with acute coronary syndrome but failed to enhance the prognostic value of the GRACE score

https://doi.org/10.18632/oncotarget.15094
20622-20629
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Tickhost conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite

https://doi.org/10.18632/oncotarget.15243
20630-20644
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma

https://doi.org/10.18632/oncotarget.15830
20645-20655
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

https://doi.org/10.18632/oncotarget.9327
20656-20666
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NADH autofluorescence a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

https://doi.org/10.18632/oncotarget.15400
20667-20678
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues

https://doi.org/10.18632/oncotarget.11557
20679-20694
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Impact of exudative diathesis induced by selenium deficiency on LncRNAs and their roles in the oxidative reduction process in broiler chick veins

https://doi.org/10.18632/oncotarget.14971
20695-20705
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metformintreated cancer cells modulate macrophage polarization through AMPKNFκB signaling

https://doi.org/10.18632/oncotarget.14982
20706-20718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Discovery and validation of potential urinary biomarkers for bladder cancer diagnosis using a pseudotargeted GCMS metabolomics method

https://doi.org/10.18632/oncotarget.14988
20719-20728
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

32Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect

https://doi.org/10.18632/oncotarget.15117
20729-20740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

IL6 secreted by cancerassociated fibroblasts promotes epithelialmesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.15119
20741-20750
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer

https://doi.org/10.18632/oncotarget.10612
20751-20765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Design sythesis and evaluation of a series of 3 or 4alkoxy substituted phenoxy derivatives as PPARs agonists

https://doi.org/10.18632/oncotarget.15198
20766-20783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.15265
20784-20793
Abstract  |  PDF  |  Full Text  |  How to cite

Ageadjusted charlson comorbidity index score as predictor of prolonged postoperative ileus in patients with colorectal cancer who underwent surgical resection

https://doi.org/10.18632/oncotarget.15285
20794-20801
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Understanding PSA and its derivatives in prediction of tumor volume: addressing health disparities in prostate cancer risk stratification

https://doi.org/10.18632/oncotarget.14903
20802-20812
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Exclusive destruction of mitotic spindles in human cancer cells

https://doi.org/10.18632/oncotarget.15343
20813-20824
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo

https://doi.org/10.18632/oncotarget.15346
20825-20833
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical significance of CSF3R SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia

https://doi.org/10.18632/oncotarget.15355
20834-20841
Abstract  |  PDF  |  Full Text  |  How to cite

Effect of captopril on radiationinduced TGFβ1 secretion in EAHy926 human umbilical vein endothelial cells

https://doi.org/10.18632/oncotarget.15356
20842-20850
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Novel involvement of RhebL1 in sphingosylphosphorylcholineinduced keratin phosphorylation and reorganization: Binding to and activation of AKT1

https://doi.org/10.18632/oncotarget.15364
20851-20864
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Diabetic concentrations of metformin inhibit plateletmediated ovarian cancer cell progression

https://doi.org/10.18632/oncotarget.15348
20865-20880
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

microRNA2103p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma

https://doi.org/10.18632/oncotarget.14930
20881-20894
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Resveratrol induces mitochondriamediated caspaseindependent apoptosis in murine prostate cancer cells

https://doi.org/10.18632/oncotarget.14947
20895-20908
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Berberineinduced autophagic cell death by elevating GRP78 levels in cancer cells

https://doi.org/10.18632/oncotarget.14959
20909-20924
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms of ESR1 UGT1A1 HCN1 MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptorpositive early breast cancer

https://doi.org/10.18632/oncotarget.14995
20925-20938
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Control of longdistance celltocell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

https://doi.org/10.18632/oncotarget.15467
20939-20960
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

https://doi.org/10.18632/oncotarget.15468
20961-20973
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines

https://doi.org/10.18632/oncotarget.15469
20974-20987
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Drp1dependent mitophagy protects against cisplatininduced apoptosis of renal tubular epithelial cells by improving mitochondrial function

https://doi.org/10.18632/oncotarget.15470
20988-21000
Abstract  |  PDF  |  Full Text  |  How to cite

The PIAS3Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

https://doi.org/10.18632/oncotarget.15471
21001-21014
Abstract  |  PDF  |  Full Text  |  How to cite

Imidazoline I2 receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via AktNrf2Smad2/3 signaling pathway

https://doi.org/10.18632/oncotarget.15472
21015-21030
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration

https://doi.org/10.18632/oncotarget.15473
21031-21043
Abstract  |  PDF  |  Full Text  |  How to cite

Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Tolllike receptor 4 signaling

https://doi.org/10.18632/oncotarget.15483
21044-21053
Abstract  |  PDF  |  Full Text  |  How to cite

Realtime nearinfrared fluorescence imaging using cRGDZW8001 for intraoperative visualization of multiple cancer types

https://doi.org/10.18632/oncotarget.15486
21054-21066
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antimicrobial peptide Epinecidin1 promotes complete skin regeneration of methicillinresistant Staphylococcus aureusinfected burn wounds in a swine model

https://doi.org/10.18632/oncotarget.15042
21067-21080
Abstract  |  PDF  |  Full Text  |  How to cite

Epigenetic silencing of miR520c leads to induced S100A4 expression and its mediated colorectal cancer progression

https://doi.org/10.18632/oncotarget.15499
21081-21094
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR133b mediated ceRNA network in colorectal cancer

https://doi.org/10.18632/oncotarget.15045
21095-21105
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis

https://doi.org/10.18632/oncotarget.15500
21106-21114
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

https://doi.org/10.18632/oncotarget.15501
21115-21127
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pevonedistat a Nedd8activating enzyme inhibitor sensitizes neoplastic Bcells to death receptormediated apoptosis

https://doi.org/10.18632/oncotarget.15050
21128-21139
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Annonaceous acetogenins mediated upregulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro

https://doi.org/10.18632/oncotarget.15502
21140-21152
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteasome inhibition enhances the efficacy of volasertibinduced mitotic arrest in AML in vitro and prolongs survival in vivo

https://doi.org/10.18632/oncotarget.15503
21153-21166
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma

https://doi.org/10.18632/oncotarget.15504
21167-21176
Abstract  |  PDF  |  Full Text  |  How to cite

Synergistic effects of the immune checkpoint inhibitor CTLA4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

https://doi.org/10.18632/oncotarget.15505
21177-21186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MCMDA: Matrix completion for MiRNAdisease association prediction

https://doi.org/10.18632/oncotarget.15061
21187-21199
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Rap2b siRNA significantly enhances the anticancer therapeutic efficacy of Adriamycin in a gold nanoshellbased drug/gene codelivery system

https://doi.org/10.18632/oncotarget.15508
21200-21211
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of patientspecific and tumorshared T cell receptor sequences in renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.15064
21212-21228
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma

https://doi.org/10.18632/oncotarget.15070
21229-21240
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

https://doi.org/10.18632/oncotarget.15071
21241-21252
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Variations in the bitterness perceptionrelated genes TAS2R38 and CA6 modify the risk for colorectal cancer in Koreans

https://doi.org/10.18632/oncotarget.15512
21253-21265
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer

https://doi.org/10.18632/oncotarget.15072
21266-21280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomescale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.15068
21281-21289
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

https://doi.org/10.18632/oncotarget.15514
21290-21304
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Granulocyte colonystimulating factor enhances the therapeutic efficacy of bone marrow mesenchymal stem cell transplantation in rats with experimental acute pancreatitis

https://doi.org/10.18632/oncotarget.15515
21305-21314
Abstract  |  PDF  |  Full Text  |  How to cite

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.15528
21315-21326
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel pathogenic splice acceptor site germline mutation in intron 14 of the APC gene in a Chinese family with familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.15570
21327-21335
Abstract  |  PDF  |  Full Text  |  How to cite

Autophagy is highly targeted among host comparative proteomes during infection with different virulent RABV strains

https://doi.org/10.18632/oncotarget.15184
21336-21350
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clerosterol from vinegarbaked radix bupleuri modifies drug transport

https://doi.org/10.18632/oncotarget.15212
21351-21361
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA34a targets epithelial to mesenchymal transitioninducing transcription factors EMTTFs and inhibits breast cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.15214
21362-21379
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR4943p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

https://doi.org/10.18632/oncotarget.15226
21380-21397
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

M2 polarization of macrophages facilitates arsenicinduced cell transformation of lung epithelial cells

https://doi.org/10.18632/oncotarget.15232
21398-21409
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA HULC as a potential prognostic biomarker in human cancers: a metaanalysis

https://doi.org/10.18632/oncotarget.15247
21410-21417
Abstract  |  PDF  |  Full Text  |  How to cite

Blockade of Rhoassociated protein kinase ROCK inhibits the contractility and invasion potential of cancer stem like cells

https://doi.org/10.18632/oncotarget.15248
21418-21428
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RASSF1A promoter methylation in highgrade serous ovarian cancer: A direct comparison study in primary tumors adjacent morphologically tumor cellfree tissues and paired circulating tumor DNA

https://doi.org/10.18632/oncotarget.15249
21429-21443
Abstract  |  PDF  |  Full Text  |  How to cite

PRSS3 is a prognostic marker in invasive ductal carcinoma of the breast

https://doi.org/10.18632/oncotarget.15590
21444-21453
Abstract  |  PDF  |  Full Text  |  How to cite

Grifolin exhibits anticancer activity by inhibiting the development and invasion of gastric tumor cells

https://doi.org/10.18632/oncotarget.15250
21454-21460
Abstract  |  PDF  |  Full Text  |  How to cite

miR106b5p promotes renal cell carcinoma aggressiveness and stemcelllike phenotype by activating Wnt/βcatenin signalling

https://doi.org/10.18632/oncotarget.15591
21461-21471
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Critically short telomeres and toxicity of chemotherapy in early breast cancer

https://doi.org/10.18632/oncotarget.15592
21472-21482
Abstract  |  PDF  |  Full Text  |  How to cite

Lynch syndromerelated small intestinal adenocarcinomas

https://doi.org/10.18632/oncotarget.15277
21483-21500
Abstract  |  PDF  |  Full Text  |  How to cite

NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4ADDB1 E3 ligase complex in prostate cancer

https://doi.org/10.18632/oncotarget.15308
21501-21515
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The combination of circulating long noncoding RNAs AK001058 INHBAAS1 MIR44352HG and CEBPAAS1 fragments in plasma serve as diagnostic markers for gastric cancer

https://doi.org/10.18632/oncotarget.15628
21516-21525
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD163 as a marker of M2 macrophage contribute to predict aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15630
21526-21538
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in longterm survivors with advanced melanoma

https://doi.org/10.18632/oncotarget.15368
21539-21553
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genomic imbalances are involved in miR30c and let7a deregulation in ovarian tumors: implications for HMGA2 expression

https://doi.org/10.18632/oncotarget.15795
21554-21560
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MMP8 polymorphism is associated with susceptibility to osteonecrosis of the femoral head in a Chinese Han population

https://doi.org/10.18632/oncotarget.15371
21561-21566
Abstract  |  PDF  |  Full Text  |  How to cite

Target of obstructive sleep apnea syndrome merge lung cancer: based on big data platform

https://doi.org/10.18632/oncotarget.15372
21567-21578
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

https://doi.org/10.18632/oncotarget.15375
21579-21598
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reappraisal of XRCC1 Arg194Trp polymorphism and glioma risk: a cumulative metaanalysis

https://doi.org/10.18632/oncotarget.15376
21599-21608
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The miR2593106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PDL1

https://doi.org/10.18632/oncotarget.15450
21609-21625
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ONC201 activates ER stress to inhibit the growth of triplenegative breast cancer cells

https://doi.org/10.18632/oncotarget.15451
21626-21638
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostainingfluorescence in situ hybridization SEiFISH

https://doi.org/10.18632/oncotarget.15452
21639-21649
Abstract  |  PDF  |  Full Text  |  How to cite

TGFβ–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC

https://doi.org/10.18632/oncotarget.15521
21650-21662
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

https://doi.org/10.18632/oncotarget.15523
21663-21673
Abstract  |  PDF  |  Full Text  |  How to cite

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways

https://doi.org/10.18632/oncotarget.15535
21674-21691
Abstract  |  PDF  |  Full Text  |  How to cite

ATM kinase sustains breast cancer stemlike cells by promoting ATG4C expression and autophagy

https://doi.org/10.18632/oncotarget.15537
21692-21709
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets

https://doi.org/10.18632/oncotarget.15558
21710-21718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR5035p confers drug resistance by targeting PUMA in colorectal carcinoma

https://doi.org/10.18632/oncotarget.15559
21719-21732
Abstract  |  PDF  |  Full Text  |  How to cite

Mitotic readout genes confer poor outcome in luminal A breast cancer tumors

https://doi.org/10.18632/oncotarget.15562
21733-21740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preclinical therapeutic efficacy of a novel bloodbrain barrierpenetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma

https://doi.org/10.18632/oncotarget.15566
21741-21753
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFRRASFOXM1βcatenin signaling axis

https://doi.org/10.18632/oncotarget.15567
21754-21769
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Next generation sequencing of extraskeletal myxoid chondrosarcoma

https://doi.org/10.18632/oncotarget.15568
21770-21777
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vitamin D and VDR in cancer cachexia and muscle regeneration

https://doi.org/10.18632/oncotarget.15583
21778-21793
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic role of programmeddeath ligand 1 PDL1 expressing tumor infiltrating lymphocytes in testicular germ cell tumors

https://doi.org/10.18632/oncotarget.15585
21794-21805
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1 AKT and MEK signaling in breast cancer

https://doi.org/10.18632/oncotarget.15586
21806-21817
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress

https://doi.org/10.18632/oncotarget.15631
21818-21833
Abstract  |  PDF  |  Full Text  |  How to cite

PIF* promotes brain remyelination locally while regulating systemic inflammation clinically relevant multiple sclerosis Msmegmatis model

https://doi.org/10.18632/oncotarget.15662
21834-21851
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Patterns of failure and clinical outcomes of definitive radiotherapy for cervical esophageal cancer

https://doi.org/10.18632/oncotarget.15665
21852-21860
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epigenetic inactivation of HOXA11 a novel functional tumor suppressor for renal cell carcinoma is associated with RCC TNM classification

https://doi.org/10.18632/oncotarget.15668
21861-21870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in nodepositive bladder cancer

https://doi.org/10.18632/oncotarget.15669
21871-21883
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SPC24 is critical for anaplastic thyroid cancer progression

https://doi.org/10.18632/oncotarget.15670
21884-21891
Abstract  |  PDF  |  Full Text  |  How to cite

Estrogen deficiency is associated with hippocampal morphological remodeling of early postmenopausal mice

https://doi.org/10.18632/oncotarget.15702
21892-21902
Abstract  |  PDF  |  Full Text  |  How to cite

Overall survival with crizotinib and nextgeneration ALK inhibitors in ALKpositive nonsmallcell lung cancer IFCT1302 CLINALK: a French nationwide cohort retrospective study

https://doi.org/10.18632/oncotarget.15746
21903-21917
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

JMJD3 suppresses stem celllike characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity

https://doi.org/10.18632/oncotarget.15747
21918-21929
Abstract  |  PDF  |  Full Text  |  How to cite

Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptorpositive HER2negative breast cancer

https://doi.org/10.18632/oncotarget.15748
21930-21937
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene regulatory pattern analysis reveals essential role of core transcriptional factors’ activation in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.15749
21938-21953
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interplay between ΔNp63 and miR1385p regulates growth metastasis and stemness of oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15752
21954-21973
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Correlations between intravoxel incoherent motion IVIM parameters and histological findings in rectal cancer: preliminary results

https://doi.org/10.18632/oncotarget.15753
21974-21983
Abstract  |  PDF  |  Full Text  |  How to cite

RNA sequencing analysis reveals protective role of kruppellike factor 3 in colorectal cancer

https://doi.org/10.18632/oncotarget.15766
21984-21993
Abstract  |  PDF  |  Full Text  |  How to cite

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

https://doi.org/10.18632/oncotarget.15777
21994-22002
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR519d impedes cisplatinresistance in breast cancer stem cells by downregulating the expression of MCL1

https://doi.org/10.18632/oncotarget.15781
22003-22013
Abstract  |  PDF  |  Full Text  |  How to cite

Celloforigin of diffuse large Bcell lymphomas determined by the Lymph2Cx assay: better prognostic indicator than Hans algorithm

https://doi.org/10.18632/oncotarget.15782
22014-22022
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hobnail variant of papillary thyroid carcinoma: molecular profiling and comparison to classical papillary thyroid carcinoma poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma

https://doi.org/10.18632/oncotarget.15786
22023-22033
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tetraspanin 8 TSPAN 8 as a potential target for radioimmunotherapy of colorectal cancer

https://doi.org/10.18632/oncotarget.15787
22034-22047
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HER2specific recombinant immunotoxin 4D5scFvPE40 passes through retrograde trafficking route and forces cells to enter apoptosis

https://doi.org/10.18632/oncotarget.15833
22048-22058
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in plateletderived growth factor B signaling pathway

https://doi.org/10.18632/oncotarget.15908
22059-22075
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low vitamin D status is associated with inflammation in patients with prostate cancer

https://doi.org/10.18632/oncotarget.16195
22076-22085
Abstract  |  PDF  |  Full Text  |  How to cite

Karyotyping and analysis of GNAS locus in intramuscular myxomas

https://doi.org/10.18632/oncotarget.14986
22086-22094
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Development and comparison of a Chinese nomogram adding multiparametric MRI information for predicting extracapsular extension of prostate cancer

https://doi.org/10.18632/oncotarget.11559
22095-22103
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A phase III trial of fludarabine bendamustine and rituximab FBR in previously treated patients with CLL

https://doi.org/10.18632/oncotarget.12054
22104-22112
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Crossing the perspectives of patients families and physicians on cancer treatment: A qualitative study

https://doi.org/10.18632/oncotarget.12770
22113-22122
Abstract  |  PDF  |  Full Text  |  How to cite

Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems

https://doi.org/10.18632/oncotarget.13641
22123-22134
Abstract  |  PDF  |  Full Text  |  How to cite

A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium ME2906 and a diode laser PNL6405EPG for local failure after chemoradiotherapy or radiotherapy for esophageal cancer

https://doi.org/10.18632/oncotarget.14029
22135-22144
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13530
22145-22165
Abstract  |  PDF  |  Full Text  |  How to cite

An early biomarker and potential therapeutic target of RUNX 3 hypermethylation in breast cancer a system review and metaanalysis

https://doi.org/10.18632/oncotarget.13125
22166-22174
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

KRAS and TP53 mutations in inflammatory bowel diseaseassociated colorectal cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.14549
22175-22186
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNAs: a rising biotarget in colorectal cancer

https://doi.org/10.18632/oncotarget.14728
22187-22202
Abstract  |  PDF  |  Full Text  |  How to cite

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14729
22203-22217
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies

https://doi.org/10.18632/oncotarget.14731
22218-22234
Abstract  |  PDF  |  Full Text  |  How to cite

RNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection

https://doi.org/10.18632/oncotarget.14755
22235-22250
Abstract  |  PDF  |  Full Text  |  How to cite

Consolidative thoracic radiotherapy for extensive stage small cell lung cancer

https://doi.org/10.18632/oncotarget.14759
22251-22261
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNAs in melanoma development and resistance to target therapy

https://doi.org/10.18632/oncotarget.14763
22262-22278
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

https://doi.org/10.18632/oncotarget.15299
22279-22298
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and LedipasvirSofosbuvir: a case report and review of literature

https://doi.org/10.18632/oncotarget.15397
22299-22303
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

https://doi.org/10.18632/oncotarget.16592
22304-22304
Correction  |  PDF  |  How to cite


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