VOLUME 8 (2017)
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About The Cover
The cover for issue 22 of Oncotarget features Figure 1C, "Representative scatter plots of apoptosis in 4T1 cells, after AnnexinV/7-AAD staining and assessment by flow cytometry," by Wang, et al.
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Table of Contents
News
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| ROS and radiotherapy: more we care |
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https://doi.org/10.18632/oncotarget.16613
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| 35482-35483 |
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| Bispecific protein targets prostate cancer |
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https://doi.org/10.18632/oncotarget.17372
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| 35484-35485 |
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| Reactivating nuclear PTEN to treat CLL |
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https://doi.org/10.18632/oncotarget.17543
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| 35486-35487 |
Editorial
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| Polymer toxicity in neurodegeneration FENIB |
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https://doi.org/10.18632/oncotarget.17772
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| 35490-35491 |
Research Perspectives
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| From rapalogs to antiaging formula |
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https://doi.org/10.18632/oncotarget.18033
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| 35492-35507 |
Priority Research Papers
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| Therapeutic inhibition of USP7PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones |
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https://doi.org/10.18632/oncotarget.16348
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| 35508-35522 |
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| Genetic landscape of extreme responders with anaplastic oligodendroglioma |
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https://doi.org/10.18632/oncotarget.16773
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| 35523-35531 |
Research Papers: Pathology
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| Expression of wildtype p53induced phosphatase 1 in diabetic epiretinal membranes |
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https://doi.org/10.18632/oncotarget.16683
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| 35532-35541 |
Research Papers: Immunology
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| Unique properties of thymic antigenpresenting cells promote epigenetic imprinting of alloantigenspecific regulatory T cells |
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https://doi.org/10.18632/oncotarget.16221
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| 35542-35557 |
Research Papers: Neuroscience
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| cAMP/PKACREBBDNF signaling pathway in hippocampus mediates cyclooxygenase 2induced learning/memory deficits of rats subjected to chronic unpredictable mild stress |
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https://doi.org/10.18632/oncotarget.16009
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| 35558-35572 |
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| Nitrobenzylthioinosine mimics adenosine to attenuate the epileptiform discharge of hippocampal neurons from epileptic rats |
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https://doi.org/10.18632/oncotarget.16012
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| 35573-35582 |
Methodological Research Paper
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| Biodegradable and biocompatible high elastic chitosan scaffold is cellfriendly both in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.14709
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| 35583-35591 |
Research Papers
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| Tumorfibroblast interactions stimulate tumor vascularization by enhancing cytokinedriven production of MMP9 by tumor cells |
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https://doi.org/10.18632/oncotarget.16022
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| 35592-35608 |
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| Elevated microRNA135a is associated with pulmonary arterial hypertension in experimental mouse model |
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https://doi.org/10.18632/oncotarget.16011
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| 35609-35618 |
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| Combined effect of body mass index and metabolic status on the risk of prevalent and incident chronic kidney disease: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.10915
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| 35619-35629 |
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| Recombinant methioninase effectively targets a Ewing’s sarcoma in a patientderived orthotopic xenograft PDOX nudemouse model |
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https://doi.org/10.18632/oncotarget.15823
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| 35630-35638 |
|
| Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma |
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https://doi.org/10.18632/oncotarget.16767
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| 35639-35655 |
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| Circulating tumor cells CTCs are associated with abnormalities in peripheral blood dendritic cells in patients with inflammatory breast cancer |
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https://doi.org/10.18632/oncotarget.10290
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| 35656-35668 |
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| Ultraconserved long noncoding RNA uc63 in breast cancer |
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https://doi.org/10.18632/oncotarget.10572
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| 35669-35680 |
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| Identification of molecular targets for esophageal carcinoma diagnosis using miRNAseq and RNAseq data from The Cancer Genome Atlas: a study of 187 cases |
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https://doi.org/10.18632/oncotarget.16051
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| 35681-35699 |
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| The prognostic impact of supraclavicular lymph node in N3IIIB stage nonsmall cell lung cancer patients treated with definitive concurrent chemoradiotherapy |
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https://doi.org/10.18632/oncotarget.16054
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| 35700-35706 |
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| Targeting CD157 in AML using a novel Fcengineered antibody construct |
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https://doi.org/10.18632/oncotarget.16060
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| 35707-35717 |
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| Salivary glycopatterns as potential biomarkers for diagnosis of gastric cancer |
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https://doi.org/10.18632/oncotarget.16082
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| 35718-35727 |
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| Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species |
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https://doi.org/10.18632/oncotarget.16113
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| 35728-35742 |
|
| Comparison of Gadoliniumenhanced MRI and 18FDG PET/PETCT for the diagnosis of brain metastases in lung cancer patients: A metaanalysis of 5 prospective studies |
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https://doi.org/10.18632/oncotarget.16182
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| 35743-35749 |
|
| LncRNA Snhg1 a nondegradable sponge for miR338 promotes expression of protooncogene CST3 in primary esophageal cancer cells |
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https://doi.org/10.18632/oncotarget.16189
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| 35750-35760 |
|
| Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase |
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https://doi.org/10.18632/oncotarget.16204
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| 35761-35775 |
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| An absence of platelet activation following thalidomide treatment in vitro or in vivo |
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https://doi.org/10.18632/oncotarget.16205
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| 35776-35782 |
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| Differential microRNA expression profiling in primary tumors and matched liver metastasis of patients with colorectal cancer |
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https://doi.org/10.18632/oncotarget.16206
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| 35783-35791 |
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| KSHV coinfection downregulates HPV16 E6 and E7 from cervical cancer cells |
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https://doi.org/10.18632/oncotarget.16207
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| 35792-35803 |
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| Binding of galectin1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells |
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https://doi.org/10.18632/oncotarget.16208
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| 35804-35823 |
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| Low numbers of preleukemic fusion genes are frequently present in umbilical cord blood without affecting DNA damage response |
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https://doi.org/10.18632/oncotarget.16211
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| 35824-35834 |
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| Antiproliferative role of recombinant lethal toxin of Bacillus anthracis on primary mammary ductal carcinoma cells revealing its therapeutic potential |
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https://doi.org/10.18632/oncotarget.16214
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| 35835-35847 |
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| Relevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype |
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https://doi.org/10.18632/oncotarget.16261
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| 35848-35862 |
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| Glutaminase inhibitor CB839 synergizes with carfilzomib in resistant multiple myeloma cells |
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https://doi.org/10.18632/oncotarget.16262
|
| 35863-35876 |
|
| Knockdown of P4HA1 inhibits neovascularization via targeting glioma stem cellendothelial cell transdifferentiation and disrupting vascular basement membrane |
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https://doi.org/10.18632/oncotarget.16270
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| 35877-35889 |
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| Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with preadipocytes/adipocytes |
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https://doi.org/10.18632/oncotarget.16271
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| 35890-35901 |
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| MicroRNAs of the mir17~92 cluster regulate multiple aspects of pancreatic tumor development and progression |
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https://doi.org/10.18632/oncotarget.16277
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| 35902-35918 |
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| Selenophosphate synthetase 1 SPS1 is required for the development and selenium homeostasis of central nervous system in chicken Gallus gallus |
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https://doi.org/10.18632/oncotarget.16283
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| 35919-35932 |
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| GABAergic neurons in nucleus accumbens are correlated to resilience and vulnerability to chronic stress for major depression |
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https://doi.org/10.18632/oncotarget.16411
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| 35933-35945 |
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| Multiple antitumor effects of Reparixin on thyroid cancer |
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https://doi.org/10.18632/oncotarget.16412
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| 35946-35961 |
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| The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease |
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https://doi.org/10.18632/oncotarget.16414
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| 35962-35972 |
|
| Identification and functional analysis of differentially expressed genes in poorly differentiated hepatocellular carcinoma using RNAseq |
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https://doi.org/10.18632/oncotarget.16415
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| 35973-35983 |
|
| Cysteine and glycinerich protein 2 CSRP2 transcript levels correlate with leukemia relapse and leukemiafree survival in adults with Bcell acute lymphoblastic leukemia and normal cytogenetics |
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https://doi.org/10.18632/oncotarget.16416
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| 35984-36000 |
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| 18FFluoride PET/CT tumor burden quantification predicts survival in breast cancer |
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https://doi.org/10.18632/oncotarget.16418
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| 36001-36011 |
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| Renal mass biopsy using Raman spectroscopy identifies malignant and benign renal tumors: potential for preoperative diagnosis |
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https://doi.org/10.18632/oncotarget.16419
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| 36012-36019 |
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| Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment |
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https://doi.org/10.18632/oncotarget.16421
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| 36020-36032 |
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| BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population |
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https://doi.org/10.18632/oncotarget.16422
|
| 36033-36039 |
|
| Regulatory network of GATA3 in pediatric acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.16424
|
| 36040-36053 |
|
| ERRF sensitizes ERBB2positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression |
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https://doi.org/10.18632/oncotarget.16425
|
| 36054-36066 |
|
| Inhibiting G protein βγ signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel |
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https://doi.org/10.18632/oncotarget.16428
|
| 36067-36081 |
|
| KIFC1 is essential for acrosome formation and nuclear shaping during spermiogenesis in the lobster Procambarus clarkii |
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https://doi.org/10.18632/oncotarget.16429
|
| 36082-36098 |
|
| Collagen type IV alpha 1 COL4A1 and collagen type XIII alpha 1 COL13A1 produced in cancer cells promote tumor budding at the invasion front in human urothelial carcinoma of the bladder |
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https://doi.org/10.18632/oncotarget.16432
|
| 36099-36114 |
|
| Identification of driver modules in pancancer via coordinating coverage and exclusivity |
|
https://doi.org/10.18632/oncotarget.16433
|
| 36115-36126 |
|
| The influence of tumor necrosis factorα on the tumorigenic Wntsignaling pathway in human mammary tissue from obese women |
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https://doi.org/10.18632/oncotarget.16632
|
| 36127-36136 |
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| Glioma stem cellsderived exosomes promote the angiogenic ability of endothelial cells through miR21/VEGF signal |
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https://doi.org/10.18632/oncotarget.16661
|
| 36137-36148 |
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| Stem cell autocrine CXCL12/CXCR4 stimulates invasion and metastasis of esophageal cancer |
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https://doi.org/10.18632/oncotarget.15254
|
| 36149-36160 |
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| Integration of the cancerrelated inflammatory response as a stratifying biomarker of survival in hepatocellular carcinoma treated with sorafenib |
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https://doi.org/10.18632/oncotarget.15322
|
| 36161-36170 |
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| Tumor and serum gammaglutamyl transpeptidase new prognostic and molecular interpretation of an old biomarker in gastric cancer |
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https://doi.org/10.18632/oncotarget.15609
|
| 36171-36184 |
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| High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin |
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https://doi.org/10.18632/oncotarget.15873
|
| 36185-36202 |
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| Search for rare protein altering variants influencing susceptibility to multiple myeloma |
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https://doi.org/10.18632/oncotarget.15874
|
| 36203-36210 |
|
| Tropomyosinrelated kinase B mediated signaling contributes to the induction of malignant phenotype of gallbladder cancer |
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https://doi.org/10.18632/oncotarget.16063
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| 36211-36224 |
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| The ovarian cancer oncobiome |
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https://doi.org/10.18632/oncotarget.16717
|
| 36225-36245 |
|
| Oncogenic features of neuromedin U in breast cancer are associated with NMUR2 expression involving crosstalk with members of the WNT signaling pathway |
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https://doi.org/10.18632/oncotarget.16121
|
| 36246-36265 |
|
| MicroRNA22 suppresses the growth migration and invasion of colorectal cancer cells through a Sp1 negative feedback loop |
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https://doi.org/10.18632/oncotarget.16742
|
| 36266-36278 |
|
| The transcriptional STAT3 is a potential target whereas transcriptional STAT5A/5B/6 are new biomarkers for prognosis in human breast carcinoma |
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https://doi.org/10.18632/oncotarget.16748
|
| 36279-36288 |
|
| Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.16749
|
| 36289-36304 |
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| Expression of embryonal stem cell transcription factors in breast cancer: Oct4 as an indicator for poor clinical outcome and tamoxifen resistance |
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https://doi.org/10.18632/oncotarget.16750
|
| 36305-36318 |
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| Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing |
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https://doi.org/10.18632/oncotarget.16751
|
| 36319-36330 |
|
| Generation of lung cancer cell lines harboring EGFR T790M mutation by CRISPR/Cas9mediated genome editing |
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https://doi.org/10.18632/oncotarget.16752
|
| 36331-36338 |
|
| Prognosis of surgery combined with different adjuvant therapies in esophageal cancer treatment: a network metaanalysis |
|
https://doi.org/10.18632/oncotarget.16193
|
| 36339-36353 |
|
| Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer |
|
https://doi.org/10.18632/oncotarget.16754
|
| 36354-36367 |
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| Involvement of miR106b in tumorigenic actions of both prolactin and estradiol |
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https://doi.org/10.18632/oncotarget.16755
|
| 36368-36382 |
|
| Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells |
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https://doi.org/10.18632/oncotarget.16756
|
| 36383-36398 |
|
| The role of nonthermal atmospheric pressure biocompatible plasma in the differentiation of osteoblastic precursor cells MC3T3E1 |
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https://doi.org/10.18632/oncotarget.16821
|
| 36399-36409 |
|
| LncRNA CHRFinduced miR489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway |
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https://doi.org/10.18632/oncotarget.16850
|
| 36410-36422 |
|
| Parkin regulates translesion DNA synthesis in response to UV radiation |
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https://doi.org/10.18632/oncotarget.16855
|
| 36423-36437 |
|
| IER5 as a promising predictive marker promotes irradiationinduced apoptosis in cervical cancer tissues from patients undergoing chemoradiotherapy |
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https://doi.org/10.18632/oncotarget.16857
|
| 36438-36448 |
|
| Resveratrol protects against early polymicrobial sepsisinduced acute kidney injury through inhibiting endoplasmic reticulum stressactivated NFκB pathway |
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https://doi.org/10.18632/oncotarget.16860
|
| 36449-36461 |
|
| Genetic variants within the cancer susceptibility region 8q24 and ovarian cancer risk in Han Chinese women |
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https://doi.org/10.18632/oncotarget.16861
|
| 36462-36468 |
|
| Minus enddirected kinesin14 KIFC1 regulates the positioning and architecture of the Golgi apparatus |
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https://doi.org/10.18632/oncotarget.16863
|
| 36469-36483 |
|
| 3Dimensional micropillar drug screening identifies FGFR2IIIC overexpression as a potential target in metastatic giant cell tumor |
|
https://doi.org/10.18632/oncotarget.16883
|
| 36484-36491 |
|
| Therapeutic benefit of Salmonella attributed to LPS and TNFα is exhaustible and dictated by tumor susceptibility |
|
https://doi.org/10.18632/oncotarget.16906
|
| 36492-36508 |
|
| Association of VEGF and VDR gene gene and gene smoking interaction on risk of multiple myeloma in Chinese Han population |
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https://doi.org/10.18632/oncotarget.16510
|
| 36509-36516 |
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| Synergistic inhibitory effects of deferasirox in combination with decitabine on leukemia cell lines SKM1 THP1 and K562 |
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https://doi.org/10.18632/oncotarget.16583
|
| 36517-36530 |
|
| Overexpression of growth differentiation factor 15 GDF15 preventing cold ischemia reperfusion I/R injury in heart transplantation through Foxo3a signaling |
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https://doi.org/10.18632/oncotarget.16607
|
| 36531-36544 |
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| Association of CKIP1 P21A polymorphism with risk of chronic heart failure in a Chinese population |
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https://doi.org/10.18632/oncotarget.16614
|
| 36545-36552 |
|
| Roles of differential expression of microRNA213p and microRNA433 in FSH regulation in rat anterior pituitary cells |
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https://doi.org/10.18632/oncotarget.16615
|
| 36553-36565 |
|
| Postpulmonary metastasectomy prognosis after curative resection for colorectal cancer |
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https://doi.org/10.18632/oncotarget.16616
|
| 36566-36577 |
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| Systematic comparison of biologically active foreign ionscodoped calcium phosphate microparticles on osteogenic differentiation in rat osteoporotic and normal mesenchymal stem cells |
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https://doi.org/10.18632/oncotarget.16618
|
| 36578-36590 |
|
| Expression signatures of HOX cluster genes in cervical cancer pathogenesis: Impact of human papillomavirus type 16 oncoprotein E7 |
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https://doi.org/10.18632/oncotarget.16619
|
| 36591-36602 |
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| Suppression of radiationinduced migration of nonsmall cell lung cancer through inhibition of Nrf2Notch Axis |
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https://doi.org/10.18632/oncotarget.16622
|
| 36603-36613 |
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| CyclicRGDyC functionalized liposomes for dualtargeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy study |
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https://doi.org/10.18632/oncotarget.16625
|
| 36614-36627 |
|
| Insulin growth factor binding protein 2 mediates the progression of lymphangioleiomyomatosis |
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https://doi.org/10.18632/oncotarget.16695
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| 36628-36638 |
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| Genetic alterations in seborrheic keratoses |
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https://doi.org/10.18632/oncotarget.16698
|
| 36639-36649 |
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| Association between EN1 rs4144782 and susceptibility of knee osteoarthritis: A casecontrol study |
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https://doi.org/10.18632/oncotarget.16842
|
| 36650-36657 |
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| Indirubin improves antioxidant and antiinflammatory functions in lipopolysaccharidechallenged mice |
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https://doi.org/10.18632/oncotarget.17560
|
| 36658-36663 |
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| Serological proteome analysis approachbased identification of ENO1 as a tumorassociated antigen and its autoantibody could enhance the sensitivity of CEA and CYFRA 211 in the detection of nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.17067
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| 36664-36673 |
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| Chemoprevention of prostate cancer in men with highgrade prostatic intraepithelial neoplasia HGPIN: a systematic review and adjusted indirect treatment comparison |
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https://doi.org/10.18632/oncotarget.16230
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| 36674-36684 |
Clinical Research Papers
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| De novo malignancy in organ transplant recipients in Taiwan: a nationwide cohort population study |
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https://doi.org/10.18632/oncotarget.13124
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| 36685-36695 |
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| Accuracy of axillary ultrasound after different neoadjuvant chemotherapy cycles in breast cancer patients |
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https://doi.org/10.18632/oncotarget.13313
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| 36696-36706 |
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| Intraperitoneal zivaflibercept effectively manages refractory ascites in colorectal cancer patients |
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https://doi.org/10.18632/oncotarget.13543
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| 36707-36715 |
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| Recombined humanized endostatin Endostar combined with chemotherapy for advanced bone and soft tissue sarcomas in stage IV |
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https://doi.org/10.18632/oncotarget.13545
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| 36716-36727 |
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| Factors that influence treatment delay in patients with colorectal cancer |
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https://doi.org/10.18632/oncotarget.13574
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| 36728-36742 |
|
| The distress thermometer as a predictor for survival in stage III lung cancer patients treated with chemotherapy |
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https://doi.org/10.18632/oncotarget.14151
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| 36743-36749 |
|
| Phase I study of QLNC120 a novel EGFR and HER2 kinase inhibitor in pretreated patients with HER2overexpressing advanced breast cancer |
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https://doi.org/10.18632/oncotarget.13581
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| 36750-36760 |
|
| Prognostic value of preoperative plasma fibrinogen level and platelettolymphocyte ratio FPLR in patients with localized upper tract urothelial carcinoma |
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https://doi.org/10.18632/oncotarget.13611
|
| 36761-36771 |
|
| Preoperative serum prealbumin as an independent prognostic indicator in patients with localized upper tract urothelial carcinoma after radical nephroureterectomy |
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https://doi.org/10.18632/oncotarget.13694
|
| 36772-36779 |
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| Vitamin D status among longterm survivors of testicular cancer |
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https://doi.org/10.18632/oncotarget.14167
|
| 36780-36786 |
Reviews
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| Noncoding RNAs as emerging regulators of epithelial to mesenchymal transition in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.16375
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| 36787-36799 |
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| A metaanalytic review of the relationship of cancer coping selfefficacy with distress and quality of life |
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https://doi.org/10.18632/oncotarget.15758
|
| 36800-36811 |
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| Diagnostic and prognostic value of blood samples for KRAS mutation identification in lung cancer: a metaanalysis |
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https://doi.org/10.18632/oncotarget.15972
|
| 36812-36823 |
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| Accuracy of Raman spectroscopy in differentiating brain tumor from normal brain tissue |
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https://doi.org/10.18632/oncotarget.15975
|
| 36824-36831 |
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| The hypoxia signalling pathway in haematological malignancies |
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https://doi.org/10.18632/oncotarget.15981
|
| 36832-36844 |
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| Prognostic value of progesterone receptor expression in ovarian cancer: a metaanalysis |
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https://doi.org/10.18632/oncotarget.15982
|
| 36845-36856 |
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| Prognostic significance of neutrophiltolymphocyte ratio in biliary tract cancers: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.16143
|
| 36857-36868 |
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| Signal transduction growth factors: the effective governance of transcription and cellular adhesion in cancer invasion |
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https://doi.org/10.18632/oncotarget.16300
|
| 36869-36884 |
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| Metaanalysis of programmed cell death 1 polymorphisms with systemic lupus erythematosus risk |
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https://doi.org/10.18632/oncotarget.16378
|
| 36885-36897 |
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| Mammalian sphingosine kinase SphK isoenzymes and isoform expression: challenges for SphK as an oncotarget |
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https://doi.org/10.18632/oncotarget.16370
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| 36898-36929 |
Corrections
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| Correction: eIF3f reduces tumor growth by directly interrupting clusterin with antiapoptotic property in cancer cells |
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https://doi.org/10.18632/oncotarget.18267
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| 36930-36930 |
|
| Correction: PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3 RB1 and multiple oncogenic signals |
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https://doi.org/10.18632/oncotarget.18268
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| 36931-36931 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
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