VOLUME 8 (2017)
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About The Cover
The cover for issue 23 of Oncotarget features Figure 5E, "The mechanism of action for BMS-345541, an IKK inhibitor. Through inhibition of IKK activity, IκB fails to get phosphorylated, leading to the inhibition of NFκB translocation across the nuclear membrane and inhibition of GD3S and GD2 expression," by Battula, et al.
Table of Contents
News
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| Selective emodin toxicity in cancer cells |
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https://doi.org/10.18632/oncotarget.16611
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| 36932-36933 |
Priority Research Papers
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| IKK inhibition by BMS345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells |
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https://doi.org/10.18632/oncotarget.16294
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| 36936-36949 |
Research Papers: Gerotarget (Focus on Aging)
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| Downregulation of protein kinase CK2 activity induces agerelated biomarkers in <i>C elegans</i> |
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https://doi.org/10.18632/oncotarget.16939
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| 36950-36963 |
Research Papers: Pathology
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| Killer cell immunoglobulinlike receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis |
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https://doi.org/10.18632/oncotarget.16936
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| 36964-36972 |
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| Pannexin1 knockout and blockade reduces ischemic stroke injury in female but not in male mice |
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https://doi.org/10.18632/oncotarget.16937
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| 36973-36983 |
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| Zerumbone ameliorates highfat dietinduced adiposity by restoring AMPKregulated lipogenesis and microRNA146b/SIRT1mediated adipogenesis |
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https://doi.org/10.18632/oncotarget.16974
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| 36984-36995 |
Research Papers: Chromosome
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| Potential biomarkers of DNA replication stress in cancer |
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https://doi.org/10.18632/oncotarget.16940
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| 36996-37008 |
Research Papers
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| Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo2 cells |
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https://doi.org/10.18632/oncotarget.10425
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| 37009-37022 |
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| Association of miR608 rs4919510 polymorphism and cancer risk: a metaanalysis based on 13664 subjects |
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https://doi.org/10.18632/oncotarget.9509
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| 37023-37031 |
|
| LoLoPicker: detecting low allelicfraction variants from lowquality cancer samples |
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https://doi.org/10.18632/oncotarget.16144
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| 37032-37040 |
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| RARα2 and PMLRAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells |
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https://doi.org/10.18632/oncotarget.10556
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| 37041-37060 |
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| The antitumor efficacy of 3C23K a glycoengineered humanized antiMISRII antibody in an ovarian cancer model is mainly mediated by engagement of immune effector cells |
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https://doi.org/10.18632/oncotarget.15715
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| 37061-37079 |
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| Comparative study of cisplatinbased definitive concurrent chemoradiotherapy with S1 versus paclitaxel for unresectable locally advanced esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.16180
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| 37080-37090 |
|
| Epigenetic upregulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells |
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https://doi.org/10.18632/oncotarget.16181
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| 37091-37103 |
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| The Spi1/PU1 transcription factor accelerates replication fork progression by increasing PP1 phosphatase in leukemia |
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https://doi.org/10.18632/oncotarget.16183
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| 37104-37114 |
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| hMAGEA2 promotes progression of breast cancer by regulating Akt and Erk1/2 pathways |
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https://doi.org/10.18632/oncotarget.16184
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| 37115-37127 |
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| Genemodified NK92MI cells expressing a chimeric CD16BBζ or CD64BBζ receptor exhibit enhanced cancerkilling ability in combination with therapeutic antibody |
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https://doi.org/10.18632/oncotarget.16201
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| 37128-37139 |
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| Mitochondrial matrix chaperone and cmyc inhibition causes enhanced lethality in glioblastoma |
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https://doi.org/10.18632/oncotarget.16202
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| 37140-37153 |
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| YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma |
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https://doi.org/10.18632/oncotarget.16209
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| 37154-37163 |
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| Metastasisassociated protein 3 in colorectal cancer determines tumor recurrence and prognosis |
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https://doi.org/10.18632/oncotarget.16332
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| 37164-37171 |
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| Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer |
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https://doi.org/10.18632/oncotarget.16420
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| 37172-37185 |
|
| Synthesis and evaluation of anthranilamidebased derivatives as FXa inhibitors |
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https://doi.org/10.18632/oncotarget.16427
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| 37186-37199 |
|
| Are pretreatment neutrophillymphocyte ratio and plateletlymphocyte ratio useful in predicting the outcomes of patients with smallcell lung cancer |
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https://doi.org/10.18632/oncotarget.16553
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| 37200-37207 |
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| Nomograms for predicting progression and efficacy of postoperation radiotherapy in IIIApN2 nonsmall cell lung cancer patients |
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https://doi.org/10.18632/oncotarget.16564
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| 37208-37216 |
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| Interleukin10 rs1800896 polymorphism is associated with increased head and neck cancer risk but not associated with its clinical stages |
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https://doi.org/10.18632/oncotarget.16660
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| 37217-37224 |
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| MiRNA profiling of gastrointestinal stromal tumors by nextgeneration sequencing |
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https://doi.org/10.18632/oncotarget.16664
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| 37225-37238 |
|
| The relevance of a low <em>JAK2</em><sup>V617F</sup> allele burden in clinical practice: a monocentric study |
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https://doi.org/10.18632/oncotarget.16744
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| 37239-37249 |
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| Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule |
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https://doi.org/10.18632/oncotarget.16763
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| 37250-37262 |
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| <i>XPG</i> gene polymorphisms and cancer susceptibility: evidence from 47 studies |
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https://doi.org/10.18632/oncotarget.16146
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| 37263-37277 |
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| Carcinomaspecific expression of P2Y<sub>11</sub> receptor and its contribution in ATPinduced purinergic signalling and cell migration in human hepatocellular carcinoma cells |
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https://doi.org/10.18632/oncotarget.16191
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| 37278-37290 |
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| Distinct MDCT imaging features to differential diagnosis of hepatic paragonimiasis and small hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.16197
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| 37291-37295 |
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| Renal sympathetic denervation guided by renal nerve stimulation to treat ventricular arrhythmia in CKD patients with ICD |
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https://doi.org/10.18632/oncotarget.16278
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| 37296-37307 |
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| <i>PPARGC1A</i> rs3736265 G>A polymorphism is associated with decreased risk of type 2 diabetes mellitus and fasting plasma glucose level |
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https://doi.org/10.18632/oncotarget.16307
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| 37308-37320 |
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| Transcriptome profiling reveals miR93p as a novel tumor suppressor in gastric cancer |
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https://doi.org/10.18632/oncotarget.16310
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| 37321-37331 |
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| Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymphnodes |
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https://doi.org/10.18632/oncotarget.16953
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| 37332-37341 |
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| Upregulation of calprotectin in mild IgEmediated ovalbumin hypersensitivity |
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https://doi.org/10.18632/oncotarget.16954
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| 37342-37354 |
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| MiR146a negatively regulates dectin1induced inflammatory responses |
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https://doi.org/10.18632/oncotarget.16958
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| 37355-37366 |
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| An inverse association between tea consumption and colorectal cancer risk |
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https://doi.org/10.18632/oncotarget.16959
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| 37367-37376 |
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| NFkB is essential for activininduced colorectal cancer migration via upregulation of PI3KMDM2 pathway |
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https://doi.org/10.18632/oncotarget.16343
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| 37377-37393 |
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| A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNAassociated processes |
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https://doi.org/10.18632/oncotarget.16962
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| 37394-37408 |
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| The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL <em>in vivo</em> |
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https://doi.org/10.18632/oncotarget.16964
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| 37409-37422 |
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| Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.16965
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| 37423-37434 |
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| High expression of B7H6 in human glioma tissues promotes tumor progression |
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https://doi.org/10.18632/oncotarget.16391
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| 37435-37447 |
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| The Nterminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelialtomesenchymal transition via a PDGFRαdependent mechanism |
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https://doi.org/10.18632/oncotarget.16394
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| 37448-37463 |
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| Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multiparametric magnetic resonance imaging |
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https://doi.org/10.18632/oncotarget.16395
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| 37464-37477 |
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| Respiratory status determines the effect of emodin on cell viability |
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https://doi.org/10.18632/oncotarget.16396
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| 37478-37490 |
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| Prognostic value of circulating endothelial cells in metastatic colorectal cancer |
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https://doi.org/10.18632/oncotarget.16397
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| 37491-37501 |
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| Folic acid phenotype FAP is a superior biomarker predicting response to pemetrexedbased chemotherapy in malignant pleural mesothelioma |
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https://doi.org/10.18632/oncotarget.16398
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| 37502-37510 |
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| Promoting oligodendroglialoriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma |
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https://doi.org/10.18632/oncotarget.16400
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| 37511-37524 |
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| Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB |
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https://doi.org/10.18632/oncotarget.16401
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| 37525-37537 |
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| Metformin inhibits proliferation and growth hormone secretion of GH3 pituitary adenoma cells |
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https://doi.org/10.18632/oncotarget.16556
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| 37538-37549 |
|
| Antitumor activity of an immunotoxin TGFαPE38 delivered by attenuated <em>Salmonella typhimurium</em> |
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https://doi.org/10.18632/oncotarget.17197
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| 37550-37560 |
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| Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population |
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https://doi.org/10.18632/oncotarget.16581
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| 37561-37567 |
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| Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX41 regulatory subunit |
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https://doi.org/10.18632/oncotarget.17247
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| 37568-37583 |
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| Contrastenhanced ultrasound evaluation of pancreatic cancer xenografts in nude mice after irradiation with subthreshold focused ultrasound for tumor ablation |
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https://doi.org/10.18632/oncotarget.16621
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| 37584-37593 |
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| Homoharringtonine suppresses imatinib resistance via the Bcl6/p53 pathway in chronic myeloid leukemia cell lines |
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https://doi.org/10.18632/oncotarget.16731
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| 37594-37604 |
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| A prospective openlabel multicenter observational study to evaluate the efficacy and safety of bortezomibmelphalanprednisone as initial treatment for autologous stem cell transplantationineligible patients with multiple myeloma |
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https://doi.org/10.18632/oncotarget.16790
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| 37605-37618 |
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| Synthetic lethal interaction between the tumour suppressor <em>STAG2</em> and its paralog <em>STAG1</em> |
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https://doi.org/10.18632/oncotarget.16838
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| 37619-37632 |
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| Involvement of Pololike kinase 1 Plk1 in quiescence regulation of cancer stemlike cells of the gastric cancer cell lines |
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https://doi.org/10.18632/oncotarget.16839
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| 37633-37645 |
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| Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.16841
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| 37646-37656 |
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| Inhibition of NLRP3 inflammasome by thioredoxininteracting protein in mouse Kupffer cells as a regulatory mechanism for nonalcoholic fatty liver disease development |
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https://doi.org/10.18632/oncotarget.17489
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| 37657-37672 |
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| Elevated CD147 expression is associated with shorter overall survival in nonsmall cell lung cancer |
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https://doi.org/10.18632/oncotarget.16948
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| 37673-37680 |
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| Modulation of the inwardly rectifying potassium channel Kir41 by the proinvasive miR5096 in glioblastoma cells |
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https://doi.org/10.18632/oncotarget.16949
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| 37681-37693 |
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| Arginine deiminase expressed in <i>vivo</i> driven by human telomerase reverse transcriptase promoter displays high hepatoma targeting and oncolytic efficiency |
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https://doi.org/10.18632/oncotarget.17032
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| 37694-37704 |
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| Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR145/Smad3 signaling pathway |
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https://doi.org/10.18632/oncotarget.17144
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| 37705-37716 |
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| KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling |
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https://doi.org/10.18632/oncotarget.17145
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| 37717-37729 |
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| Clinical and biological features of neuroblastic tumors: A comparison of neuroblastoma and ganglioneuroblastoma |
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https://doi.org/10.18632/oncotarget.17146
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| 37730-37739 |
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| Genomewide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.17147
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| 37740-37750 |
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| CRISPR/Cas9mediated <i>ApoE</i><sup>/</sup> and <i>LDLR</i><sup>/</sup> double gene knockout in pigs elevates serum LDLC and TC levels |
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https://doi.org/10.18632/oncotarget.17154
|
| 37751-37760 |
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| Polymorphisms in methotrexate transporters and their relationship to plasma methotrexate levels toxicity of highdose methotrexate and outcome of pediatric acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.17781
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| 37761-37772 |
|
| Stereochemical preference toward oncotarget: Design synthesis and <i>in vitro</i> anticancer evaluation of diastereomeric βlactams |
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https://doi.org/10.18632/oncotarget.18077
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| 37773-37782 |
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| Negative regulation of tumorinfiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway |
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https://doi.org/10.18632/oncotarget.16354
|
| 37783-37795 |
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| Tea consumption and the risk of ovarian cancer: A metaanalysis of epidemiological studies |
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https://doi.org/10.18632/oncotarget.16890
|
| 37796-37806 |
Clinical Research Papers
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| Role of systematic lymphadenectomy as part of primary debulking surgery for optimally cytoreduced advanced ovarian cancer: Reappraisal in the era of radical surgery |
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https://doi.org/10.18632/oncotarget.13696
|
| 37807-37816 |
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| Effect of interrupted time during intensity modulated radiation therapy on survival outcomes in patients with nasopharyngeal cancer |
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https://doi.org/10.18632/oncotarget.13713
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| 37817-37825 |
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| Maintenance treatment of Uracil and Tegafur UFT in responders following firstline fluorouracilbased chemotherapy in metastatic gastric cancer: a randomized phase II study |
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https://doi.org/10.18632/oncotarget.13922
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| 37826-37834 |
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| Perioperative plasma glypican3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.14271
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| 37835-37844 |
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| The combination of early treatment response and ypT stage is a novel metric to stage rectal cancer patients treated with neoadjuvant chemoradiotherapy |
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https://doi.org/10.18632/oncotarget.14708
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| 37845-37854 |
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| Texture analysis of intermediateadvanced hepatocellular carcinoma: prognosis and patients’ selection of transcatheter arterial chemoembolization and sorafenib |
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https://doi.org/10.18632/oncotarget.13675
|
| 37855-37865 |
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| Outcome of patients treated for myelodysplastic syndromes without deletion 5q after failure of lenalidomide therapy |
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https://doi.org/10.18632/oncotarget.15200
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| 37866-37874 |
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| Clinical parameters to guide decisionmaking in elderly metastatic colorectal cancer patients treated with intensive cytotoxic and antiangiogenic therapy |
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https://doi.org/10.18632/oncotarget.14333
|
| 37875-37883 |
|
| Comparison between ultrahigh and conventional mono bvalue DWI for preoperative glioma grading |
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https://doi.org/10.18632/oncotarget.14180
|
| 37884-37895 |
|
| Shortterm efficacy of different chemotherapy regimens in the treatment of advanced gastric cancer: a network metaanalysis |
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https://doi.org/10.18632/oncotarget.14664
|
| 37896-37911 |
Reviews
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| Predictors and prognosticators for survival with Yttrium90 radioembolization therapy for unresectable colorectal cancer liver metastasis |
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https://doi.org/10.18632/oncotarget.16007
|
| 37912-37922 |
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| Quantification and expert evaluation of evidence for chemopredictive biomarkers to personalize cancer treatment |
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https://doi.org/10.18632/oncotarget.13544
|
| 37923-37934 |
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| Effects of CD20+ Bcell infiltration into allografts on kidney transplantation outcomes: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.16229
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| 37935-37941 |
|
| Regulatory functional territory of PLK1 and their substrates beyond mitosis |
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https://doi.org/10.18632/oncotarget.16290
|
| 37942-37962 |
|
| Concurrent chemoradiotherapy with S1 as an alternative therapy for elderly Chinese patients with nonmetastatic esophageal squamous cancer: evidence based on a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.16302
|
| 37963-37973 |
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| Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target |
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https://doi.org/10.18632/oncotarget.16467
|
| 37974-37990 |
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| Emerging proteomics biomarkers and prostate cancer burden in Africa |
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https://doi.org/10.18632/oncotarget.16568
|
| 37991-38007 |
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| Mesenchymal stem cells and their therapeutic applications in inflammatory bowel disease |
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https://doi.org/10.18632/oncotarget.16682
|
| 38008-38021 |
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| Combination therapy in combating cancer |
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https://doi.org/10.18632/oncotarget.16723
|
| 38022-38043 |
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| Functional and therapeutic significance of EZH2 in urological cancers |
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https://doi.org/10.18632/oncotarget.16765
|
| 38044-38055 |
Case Reports
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| Monitoring of <i>KRAS</i>mutated ctDNA to discriminate pseudoprogression from true progression during antiPD1 treatment of lung adenocarcinoma |
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https://doi.org/10.18632/oncotarget.16935
|
| 38056-38060 |
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| Clinical features and surgical treatment of sacral schwannomas |
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https://doi.org/10.18632/oncotarget.16968
|
| 38061-38068 |
|
| Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease: a case report and review of the literature |
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https://doi.org/10.18632/oncotarget.16971
|
| 38069-38074 |
Corrections
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| Correction: The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer |
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https://doi.org/10.18632/oncotarget.18369
|
| 38075-38075 |
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Oncotarget ® is a registered trademark of Rapamycin Press LLC
Impact Journals ® is a registered trademark of Rapamycin Press LLC
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