Oncotarget

VOLUME 8 (2017)

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About The Cover

The cover for issue 34 of Oncotarget features Figure 3C, "SMYD2-mediated β-catenin methylation is required for expression of Wnt downstream genes and β-catenin nuclear translocation by FOXM1," from Deng, et al.

Table of Contents

News

Fledglings in p53 signaling network

https://doi.org/10.18632/oncotarget.19229
55768-55769
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Editorial

PRRT2 a network stability gene

https://doi.org/10.18632/oncotarget.19506
55770-55771
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Transglutaminase in neurological disease

https://doi.org/10.18632/oncotarget.19694
55772-55773
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Cancer’s new Achilles’ heel

https://doi.org/10.18632/oncotarget.19954
55774-55775
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Priority Research Papers

Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR3245p mediated suppression of HMGXB3 and WASF2

https://doi.org/10.18632/oncotarget.18218
55776-55789
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a novel p53 target COL17A1 that inhibits breast cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.18433
55790-55803
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Resistance to CTLA4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells

https://doi.org/10.18632/oncotarget.18437
55804-55820
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of a p53repressed gene module in breast cancer cells

https://doi.org/10.18632/oncotarget.19608
55821-55836
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Critical roles of SMYD2mediated βcatenin methylation for nuclear translocation and activation of Wnt signaling

https://doi.org/10.18632/oncotarget.19646
55837-55847
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of p16<sup>INK4A</sup> stimulates aberrant mitochondrial biogenesis through a CDK4/Rbindependent pathway

https://doi.org/10.18632/oncotarget.19862
55848-55862
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Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3kinase PI3K p85α and p85β

https://doi.org/10.18632/oncotarget.19866
55863-55876
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Priority Research Papers: Immunology

Zbtb1 controls NKp46<sup>+</sup> RORgammaT<sup>+</sup> innate lymphoid cell ILC3 development

https://doi.org/10.18632/oncotarget.19645
55877-55888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Pharynx mitochondrial [Ca<sup>2+</sup>] dynamics in live <i>C elegans</i> worms during aging

https://doi.org/10.18632/oncotarget.18600
55889-55900
Abstract  |  PDF  |  Full Text  |  How to cite

Differentially expressed lncRNAs and miRNAs with associated ceRNA networks in aged mice with postoperative cognitive dysfunction

https://doi.org/10.18632/oncotarget.18362
55901-55914
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Detecting the genetic link between Alzheimer’s disease and obesity using bioinformatics analysis of GWAS data

https://doi.org/10.18632/oncotarget.19115
55915-55919
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Pathology

NiaoDuQing granules relieve chronic kidney disease symptoms by decreasing renal fibrosis and anemia

https://doi.org/10.18632/oncotarget.18473
55920-55937
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Classical swine fever virus Shimen infection increases p53 signaling to promote cell cycle arrest in porcine alveolar macrophages

https://doi.org/10.18632/oncotarget.18997
55938-55949
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PKCθ utility in diagnosing cKIT/DOG1 double negative gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.19116
55950-55957
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Synergistic antibiotic effect of looped antimicrobial peptide CLP19 with bactericidal and bacteriostatic agents

https://doi.org/10.18632/oncotarget.18124
55958-55966
Abstract  |  PDF  |  Full Text  |  How to cite

Melatonin inhibits Sirt1dependent NAMPT and NFAT5 signaling in chondrocytes to attenuate osteoarthritis

https://doi.org/10.18632/oncotarget.18356
55967-55983
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Autophagy and Cell Death

Hyperosmotic stress stimulates autophagy via polycystin2

https://doi.org/10.18632/oncotarget.18995
55984-55997
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF7 breast cancer cells

https://doi.org/10.18632/oncotarget.19639
55998-56020
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers

<i>IL1</i> genes polymorphism and the risk of renal cell carcinoma in Chinese Han population

https://doi.org/10.18632/oncotarget.18715
56021-56029
Abstract  |  PDF  |  Full Text  |  How to cite

P62 plasmid can alleviate dietinduced obesity and metabolic dysfunctions

https://doi.org/10.18632/oncotarget.19840
56030-56040
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of NTCP expression by cyclin D1 in hepatitis B virusrelated hepatocellular carcinoma has clinical significance

https://doi.org/10.18632/oncotarget.10241
56041-56050
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade

https://doi.org/10.18632/oncotarget.17359
56051-56065
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells

https://doi.org/10.18632/oncotarget.10701
56066-56080
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer

https://doi.org/10.18632/oncotarget.9760
56081-56094
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatic B cell leukemia3 suppresses chemicallyinduced hepatocarcinogenesis in mice through altered MAPK and NFκB activation

https://doi.org/10.18632/oncotarget.10893
56095-56109
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha

https://doi.org/10.18632/oncotarget.18125
56110-56125
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeting hypoxic cancer stem cells CSCs with Doxycycline: Implications for optimizing antiangiogenic therapy

https://doi.org/10.18632/oncotarget.18445
56126-56142
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA profiling associated with nonsmall cell lung cancer: next generation sequencing detection experimental validation and prognostic value

https://doi.org/10.18632/oncotarget.18603
56143-56157
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Molecular and functional characterization of a new 3′ end KIT juxtamembrane deletion in a duodenal GIST treated with neoadjuvant Imatinib

https://doi.org/10.18632/oncotarget.19341
56158-56167
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulation of <em>LINC00161</em> correlates with tumor migration and invasion and poor prognosis of patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17040
56168-56173
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA610 suppresses osteosarcoma oncogenicity via targeting TWIST1 expression

https://doi.org/10.18632/oncotarget.17045
56174-56184
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NAcetylcysteine breaks resistance to trastuzumab caused by MUC4 overexpression in human HER2 positive BCbearing nude mice monitored by <sup>89</sup>ZrTrastuzumab and <sup>18</sup>FFDG PET imaging

https://doi.org/10.18632/oncotarget.17015
56185-56198
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A phase 1 doseescalation study of the oral histone deacetylase inhibitor abexinostat in combination with standard hypofractionated radiotherapy in advanced solid tumors

https://doi.org/10.18632/oncotarget.14147
56199-56209
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Time dependent modulation of tumor radiosensitivity by a pan HDAC inhibitor: abexinostat

https://doi.org/10.18632/oncotarget.14813
56210-56227
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hepatitis C virus core protein targets 4EBP1 expression and phosphorylation and potentiates Mycinduced liver carcinogenesis in transgenic mice

https://doi.org/10.18632/oncotarget.17280
56228-56242
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression and release of glucoseregulated protein78 GRP78 in multiple myeloma

https://doi.org/10.18632/oncotarget.17353
56243-56254
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FoxR2 promotes glioma proliferation by suppression of the p27 pathway

https://doi.org/10.18632/oncotarget.17447
56255-56266
Abstract  |  PDF  |  Full Text  |  How to cite

Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGFβ/Smad signaling pathway

https://doi.org/10.18632/oncotarget.17453
56267-56280
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of DESI2 and IP10 gene therapy significantly improves therapeutic efficacy against murine carcinoma

https://doi.org/10.18632/oncotarget.17623
56281-56295
Abstract  |  PDF  |  Full Text  |  How to cite

Eugenol alleviated breast precancerous lesions through HER2/ PI3KAKT pathwayinduced cell apoptosis and Sphase arrest

https://doi.org/10.18632/oncotarget.17626
56296-56310
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted alpha therapy using a novel CD70 targeted thorium227 conjugate in <i>in vitro</i> and <i>in vivo</i> models of renal cell carcinoma

https://doi.org/10.18632/oncotarget.16910
56311-56326
Abstract  |  PDF  |  Full Text  |  How to cite

A novel EGFRTKI inhibitor cAMPH<sub>3</sub>BO<sub>3</sub> complex combined with thermal therapy is a promising strategy to improve lung cancer treatment outcomes

https://doi.org/10.18632/oncotarget.17628
56327-56337
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification of precision treatment strategies for relapsed/ refractory multiple myeloma by functional drug sensitivity testing

https://doi.org/10.18632/oncotarget.17630
56338-56350
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways

https://doi.org/10.18632/oncotarget.16912
56351-56363
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Androgen receptor expression identifies patient with favorable outcome in operable triple negative breast cancer

https://doi.org/10.18632/oncotarget.16913
56364-56374
Abstract  |  PDF  |  Full Text  |  How to cite

IL8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERKNF&#x03BA;B pathway and reduction of JNK in HNSCC

https://doi.org/10.18632/oncotarget.16914
56375-56388
Abstract  |  PDF  |  Full Text  |  How to cite

Urine miR215p as a potential noninvasive biomarker for gastric cancer

https://doi.org/10.18632/oncotarget.16916
56389-56397
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Copy number variations of circulating cellfree DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study

https://doi.org/10.18632/oncotarget.17657
56398-56407
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tumor vasculogenic mimicry formation as an unfavorable prognostic indicator in patients with breast cancer

https://doi.org/10.18632/oncotarget.16919
56408-56416
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins

https://doi.org/10.18632/oncotarget.17662
56417-56427
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Increased expression of calponin 2 is a positive prognostic factor in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.17701
56428-56442
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Estrogen promotes tumor metastasis via estrogen receptor betamediated regulation of matrixmetalloproteinase2 in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.16992
56443-56459
Abstract  |  PDF  |  Full Text  |  How to cite

Overexpression of a functional calciumsensing receptor dramatically increases osteolytic potential of MDAMB231 cells in a mouse model of bone metastasis through epiregulinmediated osteoprotegerin downregulation

https://doi.org/10.18632/oncotarget.16999
56460-56472
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HSP90 inhibitor 17DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidantantioxidant balance

https://doi.org/10.18632/oncotarget.17007
56473-56489
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membraneassociated serine proteases

https://doi.org/10.18632/oncotarget.17009
56490-56505
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coal tar pitch extract could induce chromosomal instability of human bronchial epithelial cells mediated by spindle checkpointrelated proteins

https://doi.org/10.18632/oncotarget.17025
56506-56517
Abstract  |  PDF  |  Full Text  |  How to cite

A genomewide microRNA profiling indicates miR4245p and miR5035p as regulators of ALK expression in neuroblastoma

https://doi.org/10.18632/oncotarget.17033
56518-56532
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms of primiR2191 are associated with the susceptibility and prognosis of nonsmall cell lung cancer in a Northeast Chinese population

https://doi.org/10.18632/oncotarget.17035
56533-56541
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR451 as a new tumor marker for gastric cancer

https://doi.org/10.18632/oncotarget.17239
56542-56545
Abstract  |  PDF  |  Full Text  |  How to cite

Metformin increases chemosensitivity via gene downregulation encoding DNA replication proteins in 5Fu resistant colorectal cancer cells

https://doi.org/10.18632/oncotarget.17798
56546-56557
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The roles of ING5 in gliomas: a good marker for tumorigenesis and a potential target for gene therapy

https://doi.org/10.18632/oncotarget.17802
56558-56568
Abstract  |  PDF  |  Full Text  |  How to cite

Alternative promotion and suppression of metastasis by JNK2 governed by its phosphorylation

https://doi.org/10.18632/oncotarget.17507
56569-56581
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitochondrial protein 18 MTP18 plays a proapoptotic role in chemotherapyinduced gastric cancer cell apoptosis

https://doi.org/10.18632/oncotarget.17508
56582-56597
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Expression of CD38 in myeloma bone niche: A rational basis for the use of antiCD38 immunotherapy to inhibit osteoclast formation

https://doi.org/10.18632/oncotarget.17896
56598-56611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TDP43/HDAC6 axis promoted tumor progression and regulated nutrient deprivationinduced autophagy in glioblastoma

https://doi.org/10.18632/oncotarget.17979
56612-56625
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive factors of pathologic complete response in HER2positive and axillary lymph node positive breast cancer after neoadjuvant paclitaxel carboplatin plus with trastuzumab

https://doi.org/10.18632/oncotarget.17993
56626-56634
Abstract  |  PDF  |  Full Text  |  How to cite

Suppression of miR16 promotes tumor growth and metastasis through reversely regulating YAP1 in human cholangiocarcinoma

https://doi.org/10.18632/oncotarget.17832
56635-56650
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autosomal InDel polymorphisms for population genetic structure and differentiation analysis of Chinese Kazak ethnic group

https://doi.org/10.18632/oncotarget.17838
56651-56658
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelialmesenchymal transition

https://doi.org/10.18632/oncotarget.17855
56659-56671
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Wip1 is associated with tumorigenity and metastasis through MMP2 in human intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.18074
56672-56683
Abstract  |  PDF  |  Full Text  |  How to cite

Genomic analysis–integrated wholeexome sequencing of neuroblastomas identifies genetic mutations in axon guidance pathway

https://doi.org/10.18632/oncotarget.18079
56684-56697
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer

https://doi.org/10.18632/oncotarget.18082
56698-56713
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite
Special Collection ToC

Microwave ablation combined with EGFRTKIs versus only EGFRTKIs in advanced NSCLC patients with EGFRsensitive mutations

https://doi.org/10.18632/oncotarget.18083
56714-56725
Abstract  |  PDF  |  Full Text  |  How to cite

Longterm cigarette smoke exposure inhibits histone deacetylase 2 expression and enhances the nuclear factor&#x03BA;B activation in skeletal muscle of mice

https://doi.org/10.18632/oncotarget.18089
56726-56736
Abstract  |  PDF  |  Full Text  |  How to cite

HDLcholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in <i>CETP</i> <i>ABCA1</i> <i>APOC3</i> and <i>GALNT2</i>

https://doi.org/10.18632/oncotarget.18128
56737-56746
Abstract  |  PDF  |  Full Text  |  How to cite

Panobinostat a histone deacetylase inhibitor suppresses leptomeningeal seeding in a medulloblastoma animal model

https://doi.org/10.18632/oncotarget.18132
56747-56757
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and prognostic significance of cMet overexpression in breast cancer

https://doi.org/10.18632/oncotarget.18142
56758-56767
Abstract  |  PDF  |  Full Text  |  How to cite

IER3IP1 deficiency leads to increased &#x03B2;cell death and decreased &#x03B2;cell proliferation

https://doi.org/10.18632/oncotarget.18179
56768-56779
Abstract  |  PDF  |  Full Text  |  How to cite

<i>CASP8</i> 652 6N insertion/deletion polymorphism and overall cancer risk: evidence from 49 studies

https://doi.org/10.18632/oncotarget.18187
56780-56790
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

<i>In vivo</i> autophagy and biogenesis of autophagosomes within male haploid cells during spermiogenesis

https://doi.org/10.18632/oncotarget.18221
56791-56801
Abstract  |  PDF  |  Full Text  |  How to cite

Decitabine inhibits T cell proliferation via a novel TET2dependent mechanism and exerts potent protective effect in mouse auto and alloimmunity models

https://doi.org/10.18632/oncotarget.18063
56802-56815
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Selection of optimal molecular targets for tumorspecific imaging in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18232
56816-56828
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

DNA methylation signature of long noncoding RNA genes during human preimplantation embryonic development

https://doi.org/10.18632/oncotarget.18072
56829-56838
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Dysregulation of an Xlinked primatespecific epididymal microRNA cluster in unexplained asthenozoospermia

https://doi.org/10.18632/oncotarget.18076
56839-56849
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of glucose metabolism related gene GLUT1 in the occurrence and prognosis of colorectal cancer

https://doi.org/10.18632/oncotarget.18090
56850-56857
Abstract  |  PDF  |  Full Text  |  How to cite

BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling

https://doi.org/10.18632/oncotarget.18096
56858-56867
Abstract  |  PDF  |  Full Text  |  How to cite

Oleoylethanolamide inhibits &#x03B1;melanocyte stimulating hormonestimulated melanogenesis via ERK Akt and CREB signaling pathways in B16 melanoma cells

https://doi.org/10.18632/oncotarget.18097
56868-56879
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Heptamethine carbocyanine DZ1 dye for nearinfrared fluorescence imaging of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18131
56880-56892
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

<i>Marsdenia tenacissima</i> extract overcomes Axl and Metmediated erlotinib and gefitinib crossresistance in nonsmall cell lung cancer cells

https://doi.org/10.18632/oncotarget.18137
56893-56905
Abstract  |  PDF  |  Full Text  |  How to cite

Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for prosurvival or proapoptotic function

https://doi.org/10.18632/oncotarget.18144
56906-56920
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: a realworld experience

https://doi.org/10.18632/oncotarget.18176
56921-56931
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Relationship between the <i>TERT</i> <i>TNIP1</i> and <i>OBFC1</i> genetic polymorphisms and susceptibility to colorectal cancer in Chinese Han population

https://doi.org/10.18632/oncotarget.18378
56932-56941
Abstract  |  PDF  |  Full Text  |  How to cite

Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stressmediated paraptosislike cell death

https://doi.org/10.18632/oncotarget.18183
56942-56958
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

SOCS1 gene promoter methylation status is associated with instent restenosis after percutaneous coronary intervention

https://doi.org/10.18632/oncotarget.18398
56959-56967
Abstract  |  PDF  |  Full Text  |  How to cite

Interleukin15 stimulates natural killer cellmediated killing of both human pancreatic cancer and stellate cells

https://doi.org/10.18632/oncotarget.18185
56968-56979
Abstract  |  PDF  |  Full Text  |  How to cite

Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome

https://doi.org/10.18632/oncotarget.18252
56980-56990
Abstract  |  PDF  |  Full Text  |  How to cite

Synergistic suppression of t8;21positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors

https://doi.org/10.18632/oncotarget.18503
56991-57002
Abstract  |  PDF  |  Full Text  |  How to cite

Digoxininduced anemia among patients with atrial fibrillation and heart failure: clinical data analysis and druggene interaction network

https://doi.org/10.18632/oncotarget.18504
57003-57011
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA1075p suppresses nonsmall cell lung cancer by directly targeting oncogene epidermal growth factor receptor

https://doi.org/10.18632/oncotarget.18505
57012-57023
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Programmed differentiated natural killer cells kill leukemia cells by engaging SLAM family receptors

https://doi.org/10.18632/oncotarget.18659
57024-57038
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PLD1 overexpression promotes invasion and migration and function as a risk factor for Chinese glioma patients

https://doi.org/10.18632/oncotarget.18961
57039-57046
Abstract  |  PDF  |  Full Text  |  How to cite

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

https://doi.org/10.18632/oncotarget.18982
57047-57057
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase FAK

https://doi.org/10.18632/oncotarget.18983
57058-57071
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype tumor cell lines and normal pituitaries

https://doi.org/10.18632/oncotarget.19046
57072-57088
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Patterns and clinical significance of cervical lymph node metastasis in papillary thyroid cancer patients with Delphian lymph node metastasis

https://doi.org/10.18632/oncotarget.19047
57089-57098
Abstract  |  PDF  |  Full Text  |  How to cite

The prevalence subtypes and associated factors of hyperuricemia in lupus nephritis patients at chronic kidney disease stages 1–3

https://doi.org/10.18632/oncotarget.19051
57099-57108
Abstract  |  PDF  |  Full Text  |  How to cite

Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib

https://doi.org/10.18632/oncotarget.19055
57109-57120
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Datadriven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression ER activity and genomic complexity

https://doi.org/10.18632/oncotarget.19078
57121-57133
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mass spectrometrybased assay for the molecular diagnosis of glioma: concomitant detection of chromosome 1p/19q codeletion and <I>IDH1</I> <I>IDH2</I> and <I>TERT</I> mutation status

https://doi.org/10.18632/oncotarget.19103
57134-57148
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Small molecular floribundiquinone B derived from medicinal plants inhibits acetylcholinesterase activity

https://doi.org/10.18632/oncotarget.19169
57149-57162
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Cblb predicts postoperative survival in patients with resectable pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18714
57163-57173
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR2233p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19170
57174-57186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Morusin inhibits cell proliferation and tumor growth by downregulating cMyc in human gastric cancer

https://doi.org/10.18632/oncotarget.19231
57187-57200
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The ketogenic diet is not feasible as a therapy in a CD1 nu/nu mouse model of renal cell carcinoma with features of Stauffer’s syndrome

https://doi.org/10.18632/oncotarget.19306
57201-57215
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ARD1mediated aurora kinase A acetylation promotes cell proliferation and migration

https://doi.org/10.18632/oncotarget.19332
57216-57230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Assessment of nearinfrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor &#x03B1;2 antibody by fluorescence molecular tomography

https://doi.org/10.18632/oncotarget.19569
57231-57245
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NSC30049 inhibits Chk1 pathway in 5FUresistant CRC bulk and stem cell populations

https://doi.org/10.18632/oncotarget.19778
57246-57264
Abstract  |  PDF  |  Full Text  |  How to cite

Folate metabolism genetic polymorphisms and meningioma and glioma susceptibility in adults

https://doi.org/10.18632/oncotarget.18986
57265-57277
Abstract  |  PDF  |  Full Text  |  How to cite

Prostate cancer diagnosis using epigenetic biomarkers 3D highcontent imaging and probabilistic cellbycell classifiers

https://doi.org/10.18632/oncotarget.18985
57278-57301
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integration of ALV into <i>CTDSPL</i> and <i>CTDSPL2</i> genes in Bcell lymphomas promotes cell immortalization migration and survival

https://doi.org/10.18632/oncotarget.19328
57302-57315
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

An updated metaanalysis of amantadine for treating dyskinesia in Parkinson’s disease

https://doi.org/10.18632/oncotarget.17622
57316-57326
Abstract  |  PDF  |  Full Text  |  How to cite

Prognositic value of CD73adenosinergic pathway in solid tumor: A metaanalysis and systematic review

https://doi.org/10.18632/oncotarget.16905
57327-57336
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Bevacizumab combined with chemotherapy for glioblastoma: a metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.16924
57337-57344
Abstract  |  PDF  |  Full Text  |  How to cite

Association of apelin and apelin receptor with the risk of coronary artery disease: a metaanalysis of observational studies

https://doi.org/10.18632/oncotarget.17360
57345-57355
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical outcomes of WBRT plus EGFRTKIs versus WBRT or TKIs alone for the treatment of cerebral metastatic NSCLC patients: a metaanalysis

https://doi.org/10.18632/oncotarget.19054
57356-57364
Abstract  |  PDF  |  Full Text  |  How to cite

Docetaxel versus docetaxel plus cisplatin for nonsmallcell lung cancer: a metaanalysis of randomized clinical trials

https://doi.org/10.18632/oncotarget.17071
57365-57378
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of the incidence and risks of interstitial lung disease and QTc prolongation in nonsmallcell lung cancer patients treated with ALK inhibitors

https://doi.org/10.18632/oncotarget.18283
57379-57385
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic role of tumorinfiltrating lymphocytes in gastric cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.18065
57386-57398
Abstract  |  PDF  |  Full Text  |  How to cite

Combination therapy versus pharmacotherapy endoscopic variceal ligation or the transjugular intrahepatic portosystemic shunt alone in the secondary prevention of esophageal variceal bleeding: a metaanalysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.18143
57399-57408
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of <i>P73</i> polymorphisms with susceptibilities of cervical carcinoma: a metaanalysis

https://doi.org/10.18632/oncotarget.18164
57409-57413
Abstract  |  PDF  |  Full Text  |  How to cite

Systematic review and metaanalysis of the efficacy of breast conservation therapy followed by radiotherapy in four breast cancer subtypes

https://doi.org/10.18632/oncotarget.18205
57414-57420
Abstract  |  PDF  |  Full Text  |  How to cite

Association between 8q24 rs6983267 polymorphism and cancer susceptibility: a metaanalysis involving 170737 subjects

https://doi.org/10.18632/oncotarget.18960
57421-57439
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Lack of association between NAT2 polymorphism and prostate cancer risk: a metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.19023
57440-57450
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

<em>BACH2</em> promotes indolent clinical presentation in Waldenström macroglobulinemia

https://doi.org/10.18632/oncotarget.9917
57451-57459
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of neutrophiltolymphocyte ratio in patients with malignant pleural mesothelioma: a metaanalysis

https://doi.org/10.18632/oncotarget.15404
57460-57469
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Evaluation on efficacy and safety of the addition of Xknife therapy to gefitinib in NSCLC patients with symptomatic brain metastases

https://doi.org/10.18632/oncotarget.10420
57470-57476
Abstract  |  PDF  |  Full Text  |  How to cite

Features and risk factors of carotid atherosclerosis in a population with high stroke incidence in China

https://doi.org/10.18632/oncotarget.15415
57477-57488
Abstract  |  PDF  |  Full Text  |  How to cite

Neutrophiltolymphocyte ratio and neurological deterioration following acute cerebral hemorrhage

https://doi.org/10.18632/oncotarget.15423
57489-57494
Abstract  |  PDF  |  Full Text  |  How to cite

Different longterm oncologic outcomes after radical surgical resection for neuroendocrine carcinoma and adenocarcinoma of the stomach

https://doi.org/10.18632/oncotarget.15488
57495-57504
Abstract  |  PDF  |  Full Text  |  How to cite

Efficacy and safety of a reduced calcineurin inhibitor dose combined with mycophenolate mofetil in liver transplant patients with chronic renal dysfunction

https://doi.org/10.18632/oncotarget.15490
57505-57515
Abstract  |  PDF  |  Full Text  |  How to cite

Preoperative monocytelymphocyte and neutrophillymphocyte but not plateletlymphocyte ratios are predictive of clinical outcomes in resected patients with nonmetastatic Siewert type II/III adenocarcinoma of esophagogastric junction: a prospective cohort study the AMONP corhort

https://doi.org/10.18632/oncotarget.15497
57516-57527
Abstract  |  PDF  |  Full Text  |  How to cite

Biomarker analysis of the phase 3 TORCH trial for first line erlotinib <i>versus</i> chemotherapy in advanced nonsmall cell lung cancer patients

https://doi.org/10.18632/oncotarget.15725
57528-57536
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The application of IS6110baced loopmediated isothermal amplification LAMP in the early diagnosis of tuberculous meningitis

https://doi.org/10.18632/oncotarget.15734
57537-57542
Abstract  |  PDF  |  Full Text  |  How to cite

Association of preoperative depressive and anxiety symptoms with fiveyear survival of glioma and meningioma patients: a prospective cohort study

https://doi.org/10.18632/oncotarget.15743
57543-57551
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma

https://doi.org/10.18632/oncotarget.15744
57552-57573
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

<i>TOP2A GGH</i> and <i>PECAM1</i> are associated with hematogenous lymph node and peritoneal recurrence in stage II/III gastric cancer patients enrolled in the ACTSGC study

https://doi.org/10.18632/oncotarget.15895
57574-57582
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preoperative assessment of mitral valve abnormalities in left atrial myxoma patients using cardiac CT

https://doi.org/10.18632/oncotarget.16139
57583-57593
Abstract  |  PDF  |  Full Text  |  How to cite

Risk of aortic aneurysm and dissection in patients with autosomaldominant polycystic kidney disease: a nationwide populationbased cohort study

https://doi.org/10.18632/oncotarget.16338
57594-57604
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reviews

Biological effects and epidemiological consequences of arsenic exposure and reagents that can ameliorate arsenic damage <em>in vivo</em>

https://doi.org/10.18632/oncotarget.17745
57605-57621
Abstract  |  PDF  |  Full Text  |  How to cite

The fat and the bad: Mature adipocytes key actors in tumor progression and resistance

https://doi.org/10.18632/oncotarget.18038
57622-57641
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison among fertilitysparing therapies for well differentiated earlystage endometrial carcinoma and complex atypical hyperplasia

https://doi.org/10.18632/oncotarget.17588
57642-57653
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Targeted therapies for gastric cancer: failures and hopes from clinical trials

https://doi.org/10.18632/oncotarget.14825
57654-57669
Abstract  |  PDF  |  Full Text  |  How to cite

Treatments of traumatic neuropathic pain: a systematic review

https://doi.org/10.18632/oncotarget.16917
57670-57679
Abstract  |  PDF  |  Full Text  |  How to cite

Driver genes in nonsmall cell lung cancer: Characteristics detection methods and targeted therapies

https://doi.org/10.18632/oncotarget.17016
57680-57692
Abstract  |  PDF  |  Full Text  |  How to cite
Special Collection ToC

Promising landscape for regulating macrophage polarization: epigenetic viewpoint

https://doi.org/10.18632/oncotarget.17027
57693-57706
Abstract  |  PDF  |  Full Text  |  How to cite

The role of autophagy in hepatocellular carcinoma: friend or foe

https://doi.org/10.18632/oncotarget.17202
57707-57722
Abstract  |  PDF  |  Full Text  |  How to cite

Augmented expression of pololike kinase 1 indicates poor clinical outcome for breast patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17301
57723-57732
Abstract  |  PDF  |  Full Text  |  How to cite

Targeting metabolism and AMPactivated kinase with metformin to sensitize nonsmall cell lung cancer NSCLC to cytotoxic therapy: translational biology and rationale for current clinical trials

https://doi.org/10.18632/oncotarget.17496
57733-57754
Abstract  |  PDF  |  Full Text  |  How to cite

The prognostic value of long noncoding RNAs in prostate cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17645
57755-57765
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Insights from animal models of bladder cancer: recent advances challenges and opportunities

https://doi.org/10.18632/oncotarget.17714
57766-57781
Abstract  |  PDF  |  Full Text  |  How to cite

Vitamin K and its analogs: Potential avenues for prostate cancer management

https://doi.org/10.18632/oncotarget.17997
57782-57799
Abstract  |  PDF  |  Full Text  |  How to cite

Formation function and exhaustion of notochordal cytoplasmic vacuoles within intervertebral disc: current understanding and speculation

https://doi.org/10.18632/oncotarget.18101
57800-57812
Abstract  |  PDF  |  Full Text  |  How to cite

The reverse Warburg effect is likely to be an Achilles’ heel of cancer that can be exploited for cancer therapy

https://doi.org/10.18632/oncotarget.18175
57813-57825
Abstract  |  PDF  |  Full Text  |  How to cite

The efficacy of antiPD1/PDL1 therapy and its comparison with EGFRTKIs for advanced nonsmallcell lung cancer

https://doi.org/10.18632/oncotarget.18406
57826-57835
Abstract  |  PDF  |  Full Text  |  How to cite

Epigenetic regulation during the differentiation of stem cells to germ cells

https://doi.org/10.18632/oncotarget.18444
57836-57844
Abstract  |  PDF  |  Full Text  |  How to cite

Implementation and utilization of the molecular tumor board to guide precision medicine

https://doi.org/10.18632/oncotarget.18471
57845-57854
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

p53 p63 and p73 in the wonderland of <i>S cerevisiae</i>

https://doi.org/10.18632/oncotarget.18506
57855-57869
Abstract  |  PDF  |  Full Text  |  How to cite

The PI3K/Akt pathway: a critical player in intervertebral disc degeneration

https://doi.org/10.18632/oncotarget.18628
57870-57881
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

Genomic analysis of exceptional responder to regorafenib in treatmentrefractory metastatic rectal cancer: a case report and review of the literature

https://doi.org/10.18632/oncotarget.18357
57882-57888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pseudoprogression in microsatellite instabilityhigh colorectal cancer during treatment with combination T cell mediated immunotherapy: a case report and literature review

https://doi.org/10.18632/oncotarget.18361
57889-57897
Abstract  |  PDF  |  Full Text  |  How to cite

Dramatic response of CTNNB1 and VEGFR2 mutant temporal bone squamous cell carcinoma to bevacizumab in combination with pemetrexed

https://doi.org/10.18632/oncotarget.19649
57898-57904
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: A novel highly potent trivalent TGFβ receptor trap inhibits earlystage tumorigenesis and tumor cell invasion in murine Ptendeficient prostate glands

https://doi.org/10.18632/oncotarget.20370
57905-57905
Correction  |  PDF  |  How to cite

Correction: Increased autophagy in fibroblastlike synoviocytes leads to immune enhancement potential in rheumatoid arthritis

https://doi.org/10.18632/oncotarget.20371
57906-57906
Correction  |  PDF  |  How to cite

Research Papers

C1orf64 is a novel androgen receptor target gene and coregulator that interacts with 1433 protein in breast cancer

https://doi.org/10.18632/oncotarget.17826
57907-57933
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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