Oncotarget

VOLUME 8 (2017)

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About The Cover

The cover for issue 37 of Oncotarget features Figure 1F, "Cisplatin-treated glands showed morphological changes matching apoptosis and an induction of cleaved caspase 3 expression in the epithelial lining of the mammary duct," by de Groot, et al.

Table of Contents

Editorial

Viral inhibitions of PACTinduced RIGI activation

https://doi.org/10.18632/oncotarget.18928
60725-60726
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Research Perspectives

Blocking epithelialtomesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen

https://doi.org/10.18632/oncotarget.18337
60727-60749
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Priority Research Papers

Intraductal cisplatin treatment in a BRCAassociated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice

https://doi.org/10.18632/oncotarget.18490
60750-60763
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Changes of peripheral lymphocyte subsets and cytokine environment during aging and deteriorating gastrointestinal tract health status

https://doi.org/10.18632/oncotarget.18485
60764-60777
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Research Papers: Pathology

Reversal effect of Jagged1 signaling inhibition on CCl4induced hepatic fibrosis in rats

https://doi.org/10.18632/oncotarget.18484
60778-60788
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Ilomastat a synthetic inhibitor of MMPs prevents lung injury induced by γray irradiation in mice

https://doi.org/10.18632/oncotarget.18487
60789-60808
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers: Immunology

Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia

https://doi.org/10.18632/oncotarget.17955
60809-60825
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human monocytederived dendritic cells exposed to hyperthermia show a distinct gene expression profile and selective upregulation of IGFBP6

https://doi.org/10.18632/oncotarget.18338
60826-60840
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Analyses of a wholegenome interclade recombination map of hepatitis delta virus suggest a host polymerasedriven and viral RNA structurepromoted templateswitching mechanism for viral RNA recombination

https://doi.org/10.18632/oncotarget.18339
60841-60859
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HNSCC subverts PBMCs to secrete soluble products that promote tumor cell proliferation

https://doi.org/10.18632/oncotarget.18486
60860-60874
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Epigenetic hypomethylation and upregulation of matrix metalloproteinase 9 in Kawasaki disease

https://doi.org/10.18632/oncotarget.19650
60875-60891
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Research Papers: Autophagy and Cell Death

AntiCD47 antibodies induce phagocytosis of live malignant B cells by macrophages via the Fc domain resulting in cell death by phagoptosis

https://doi.org/10.18632/oncotarget.18492
60892-60903
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Research Papers

Unique synergistic formulation of curcumin epicatechin gallate and resveratrol tricurin suppresses HPV E6 eliminates HPV+ cancer cells and inhibits tumor progression

https://doi.org/10.18632/oncotarget.16648
60904-60916
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Decreased WWOX expression promotes angiogenesis in osteosarcoma

https://doi.org/10.18632/oncotarget.17126
60917-60932
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Association of STAT4 and PTPN22 polymorphisms and their interactions with type1 autoimmune hepatitis susceptibility in Chinese Han children

https://doi.org/10.18632/oncotarget.17458
60933-60940
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effect of aFGF in neonatal hypoxicischaemic brain injury

https://doi.org/10.18632/oncotarget.17524
60941-60953
Abstract  |  PDF  |  Full Text  |  How to cite

Expression of glucose transporter 1 and prognosis in nonsmall cell lung cancer: a pooled analysis of 1665 patients

https://doi.org/10.18632/oncotarget.17604
60954-60961
Abstract  |  PDF  |  Full Text  |  How to cite

Hepatitis B virus X proteininduced upregulation of CAT1 stimulates proliferation and inhibits apoptosis in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.17631
60962-60974
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic defects of the IRF1mediated major histocompatibility complex class I antigen presentation pathway occur prevalently in the JAK2 gene in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.17689
60975-60986
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Autophagyrelated gene expression is an independent prognostic indicator of glioma

https://doi.org/10.18632/oncotarget.17719
60987-61000
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tim3 inhibits lowdensity lipoproteininduced atherogenic responses in human umbilical vein endothelial cells

https://doi.org/10.18632/oncotarget.17720
61001-61010
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGFβ1/Smad3 signaling

https://doi.org/10.18632/oncotarget.17723
61011-61024
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Orphan nuclear receptor Nur77 inhibits poly I:Ctriggered acute liver inflammation by inducing the ubiquitinediting enzyme A20

https://doi.org/10.18632/oncotarget.17731
61025-61035
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High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.17717
61036-61047
Abstract  |  PDF  |  Full Text  |  How to cite

Quantitative assessment of the effect of pregestational diabetes and risk of adverse maternal perinatal and neonatal outcomes

https://doi.org/10.18632/oncotarget.17824
61048-61056
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of Xlinked inhibitor of apoptosis protein by ‘7Benzylidenenaltrexone maleate’ sensitizes pancreatic cancer cells to TRAILinduced apoptosis

https://doi.org/10.18632/oncotarget.17841
61057-61071
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An immunocompetent mouse model of human glioblastoma

https://doi.org/10.18632/oncotarget.17851
61072-61082
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Cuprous oxide nanoparticles inhibit the growth of cervical carcinoma by inducing autophagy

https://doi.org/10.18632/oncotarget.17854
61083-61092
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Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.17862
61093-61106
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Integrated transcriptomic analysis of distancerelated field cancerization in rectal cancer patients

https://doi.org/10.18632/oncotarget.17864
61107-61117
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Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3KAKTP21 signaling

https://doi.org/10.18632/oncotarget.18010
61118-61132
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of calponin h1 confers anoikis resistance and tumor progression in the development of highgrade serous carcinoma originating from the fallopian tube epithelium

https://doi.org/10.18632/oncotarget.18024
61133-61145
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Application of luteolin nanomicelles antiglioma effect with improvement in vitro and in vivo

https://doi.org/10.18632/oncotarget.18019
61146-61162
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Clinically relevant morphological structures in breast cancer represent transcriptionally distinct tumor cell populations with varied degrees of epithelialmesenchymal transition and CD44+CD24 stemness

https://doi.org/10.18632/oncotarget.18022
61163-61180
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Characteristics of ovarian cancer detection by a nearinfrared fluorescent probe activated by human NADPH: quinone oxidoreductase isozyme 1 hNQO1

https://doi.org/10.18632/oncotarget.18044
61181-61192
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Improvement of mitochondrial function mediated the neuroprotective effect of 54hydroxy3dimethoxybenzylidene2thioxo4thiazolidinone in rats with cerebral ischemiareperfusion injuries

https://doi.org/10.18632/oncotarget.18048
61193-61202
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic value and preoperative predictors of microvascular invasion in solitary hepatocellular carcinoma ≤ 5 cm without macrovascular invasion

https://doi.org/10.18632/oncotarget.18049
61203-61214
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Identification of hMex3A and its effect on human bladder cancer cell proliferation

https://doi.org/10.18632/oncotarget.18050
61215-61225
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Andrographolide inhibits arrhythmias and is cardioprotective in rabbits

https://doi.org/10.18632/oncotarget.18051
61226-61238
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Multiple genespecific DNA methylation in blood leukocytes and colorectal cancer risk: a casecontrol study in China

https://doi.org/10.18632/oncotarget.18054
61239-61252
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Short stature homeobox 2 methylation as a potential noninvasive biomarker in bronchial aspirates for lung cancer diagnosis

https://doi.org/10.18632/oncotarget.18056
61253-61263
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identification and causes of metabonomic difference between orthotopic and subcutaneous xenograft of pancreatic cancer

https://doi.org/10.18632/oncotarget.18057
61264-61281
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical roles of the aberrantly expressed lncRNAs in lung squamous cell carcinoma: a study based on RNAsequencing and microarray data mining

https://doi.org/10.18632/oncotarget.18058
61282-61304
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene polymorphisms in the PI3K/AKT/mTOR signaling pathway contribute to prostate cancer susceptibility in Chinese men

https://doi.org/10.18632/oncotarget.18064
61305-61317
Abstract  |  PDF  |  Full Text  |  How to cite

A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsamiR1853p binding site

https://doi.org/10.18632/oncotarget.18095
61318-61326
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Integrative bioinformatics analysis identifies ROBO1 as a potential therapeutic target modified by miR218 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18099
61327-61337
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HDAC10 promotes angiogenesis in endothelial cells through the PTPN22/ERK axis

https://doi.org/10.18632/oncotarget.18130
61338-61349
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Thioredoxin plays a key role in retinal neuropathy prior to endothelial damage in diabetic mice

https://doi.org/10.18632/oncotarget.18134
61350-61364
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Prognostic value of the creactive protein/prognostic nutritional index ratio after hip fracture surgery in the elderly population

https://doi.org/10.18632/oncotarget.18135
61365-61372
Abstract  |  PDF  |  Full Text  |  How to cite

Cterminal kinesin motor KIFC1 participates in facilitating proper cell division of human seminoma

https://doi.org/10.18632/oncotarget.18139
61373-61384
Abstract  |  PDF  |  Full Text  |  How to cite

Genistein improves inflammatory response and colonic function through NFκB signal in DSSinduced colonic injury

https://doi.org/10.18632/oncotarget.18219
61385-61392
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Extranodal extension status is a powerful prognostic factor in stage III colorectal cancer

https://doi.org/10.18632/oncotarget.18223
61393-61403
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Preoperative chronic kidney disease predicts poor oncological outcomes after radical cystectomy in patients with muscleinvasive bladder cancer

https://doi.org/10.18632/oncotarget.18248
61404-61414
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interfamilial and intrafamilial phenotypic variability in three Sicilian families with AndersonFabry disease

https://doi.org/10.18632/oncotarget.18250
61415-61424
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Expression of LAG3 defines exhaustion of intratumoral PD1+ T cells and correlates with poor outcome in follicular lymphoma

https://doi.org/10.18632/oncotarget.18251
61425-61439
Abstract  |  PDF  |  Full Text  |  How to cite

Wogonoside inhibits IL1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis

https://doi.org/10.18632/oncotarget.18374
61440-61456
Abstract  |  PDF  |  Full Text  |  How to cite

Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas

https://doi.org/10.18632/oncotarget.18390
61457-61474
Abstract  |  PDF  |  Full Text  |  How to cite

RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR186/Ecadherin/EMT pathway

https://doi.org/10.18632/oncotarget.18424
61475-61486
Abstract  |  PDF  |  Full Text  |  How to cite

Specific microRNA library of IFNτ on bovine endometrial epithelial cells

https://doi.org/10.18632/oncotarget.18470
61487-61498
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Knockdown of MALAT1 expression inhibits HUVEC proliferation by upregulation of miR320a and downregulation of FOXM1 expression

https://doi.org/10.18632/oncotarget.18507
61499-61509
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling

https://doi.org/10.18632/oncotarget.18604
61510-61527
Abstract  |  PDF  |  Full Text  |  How to cite

Enhanced chemosensitization of anoikisresistant melanoma cells through syndecan2 upregulation upon anchorage independency

https://doi.org/10.18632/oncotarget.18616
61528-61537
Abstract  |  PDF  |  Full Text  |  How to cite

Targeted exome sequencing of Korean triplenegative breast cancer reveals homozygous deletions associated with poor prognosis of adjuvant chemotherapytreated patients

https://doi.org/10.18632/oncotarget.18618
61538-61550
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The 2aminoethoxydiphenyl borate analog DPB161 blocks storeoperated Ca2+ entry in acutely dissociated rat submandibular cells

https://doi.org/10.18632/oncotarget.18623
61551-61560
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA ZFAS1 correlates with clinical progression and prognosis in cancer patients

https://doi.org/10.18632/oncotarget.18633
61561-61569
Abstract  |  PDF  |  Full Text  |  How to cite

Combined reninangiotensinaldosterone system blockade and statin therapy effectively reduces the risk of cerebrovascular accident in autosomal dominant polycystic kidney disease: a nationwide populationbased cohort study

https://doi.org/10.18632/oncotarget.18636
61570-61582
Abstract  |  PDF  |  Full Text  |  How to cite

Risk score based on three mRNA expression predicts the survival of bladder cancer

https://doi.org/10.18632/oncotarget.18642
61583-61591
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Accelerated tumor growth under intermittent hypoxia is associated with hypoxiainducible factor1dependent adaptive responses to hypoxia

https://doi.org/10.18632/oncotarget.18644
61592-61603
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human steroid sulfatase induces Wnt/βcatenin signaling and epithelialmesenchymal transition by upregulating Twist1 and HIF1α in human prostate and cervical cancer cells

https://doi.org/10.18632/oncotarget.18645
61604-61617
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Programmed cell deathligand 1 expression and immunoscore in stage II and III nonsmall cell lung cancer patients receiving adjuvant chemotherapy

https://doi.org/10.18632/oncotarget.18651
61618-61625
Abstract  |  PDF  |  Full Text  |  How to cite

Transducin βlike 1 Xlinked receptor 1 correlates with clinical prognosis and clinicopathological characteristics in human solid carcinomas

https://doi.org/10.18632/oncotarget.18650
61626-61636
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Polymorphisms of protamine genes contribute to male infertility susceptibility in the Chinese Han population

https://doi.org/10.18632/oncotarget.18660
61637-61645
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of betulinic acid and chidamide synergistically inhibits EpsteinBarr virus replication through overgeneration of reactive oxygen species

https://doi.org/10.18632/oncotarget.18661
61646-61661
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance of the size and number of lymph nodes on pre and post neoadjuvant chemotherapy CT in patients with pN0 esophageal squamous cell carcinoma: a 5year followup study

https://doi.org/10.18632/oncotarget.18665
61662-61673
Abstract  |  PDF  |  Full Text  |  How to cite

Silencing IGFBP2 decreases pancreatic cancer metastasis and enhances chemotherapeutic sensitivity

https://doi.org/10.18632/oncotarget.18669
61674-61686
Abstract  |  PDF  |  Full Text  |  How to cite

Increased circular RNA UBAP2 acts as a sponge of miR143 to promote osteosarcoma progression

https://doi.org/10.18632/oncotarget.18671
61687-61697
Abstract  |  PDF  |  Full Text  |  How to cite

Endoplasmic reticulum aminopeptidase 2 involvement in metastasis of oral cavity squamous cell carcinoma discovered by proteome profiling of primary cancer cells

https://doi.org/10.18632/oncotarget.18680
61698-61708
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Decreased expression of MT1E is a potential biomarker of prostate cancer progression

https://doi.org/10.18632/oncotarget.18683
61709-61718
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Additional Nglycosylation mutation in the major hydrophilic region of hepatitis B virus S gene is a risk indicator for hepatocellular carcinoma occurrence in patients with coexistence of HBsAg/antiHBs

https://doi.org/10.18632/oncotarget.18682
61719-61730
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer

https://doi.org/10.18632/oncotarget.18686
61731-61741
Abstract  |  PDF  |  Full Text  |  How to cite

Overexpression of stathmin plays a pivotal role in the metastasis of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.18687
61742-61760
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ONC201 selectively induces apoptosis in cutaneous Tcell lymphoma cells via activating proapoptotic integrated stress response and inactivating JAK/STAT and NFκB pathways

https://doi.org/10.18632/oncotarget.18688
61761-61776
Abstract  |  PDF  |  Full Text  |  How to cite

Polymorphisms in mitotic checkpointrelated genes can influence survival outcomes of earlystage nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.18693
61777-61785
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gene expression profiling to predict recurrence of advanced squamous cell carcinoma of the tongue: discovery and external validation

https://doi.org/10.18632/oncotarget.18692
61786-61799
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MOC31PE immunotoxin – targeting peritoneal metastasis from epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.18694
61800-61809
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Trypsinprotease activated receptor2 signaling contributes to pancreatic cancer pain

https://doi.org/10.18632/oncotarget.18696
61810-61823
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization

https://doi.org/10.18632/oncotarget.18699
61824-61836
Abstract  |  PDF  |  Full Text  |  How to cite

Cardiotoxicity of trastuzumab in patients with HER2positive gastric cancer

https://doi.org/10.18632/oncotarget.18700
61837-61845
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

2Acetylamino3[42acetylamino2carboxyethylsulfanylcarbonylamino phenyl carbamoylsulfanyl] propionic acid a glutathione reductase inhibitor induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells

https://doi.org/10.18632/oncotarget.18705
61846-61860
Abstract  |  PDF  |  Full Text  |  How to cite

Evaluation of hepatectomy and palliative local treatments for gastric cancer patients with liver metastases: a propensity score matching analysis

https://doi.org/10.18632/oncotarget.18709
61861-61875
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

STAT3 mutation impacts biological and clinical features of TLGL leukemia

https://doi.org/10.18632/oncotarget.18711
61876-61889
Abstract  |  PDF  |  Full Text  |  How to cite

Functional role of SETD2 BAP1 PARP3 and PBRM1 candidate genes on the regulation of hTERT gene expression

https://doi.org/10.18632/oncotarget.18712
61890-61900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Astrocyteelevated gene1 confers resistance to pemetrexed in nonsmall cell lung cancer by upregulating thymidylate synthase expression

https://doi.org/10.18632/oncotarget.18717
61901-61916
Abstract  |  PDF  |  Full Text  |  How to cite

Potential link between Fusobacterium enrichment and DNA methylation accumulation in the inflammatory colonic mucosa in ulcerative colitis

https://doi.org/10.18632/oncotarget.18716
61917-61926
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

LEPR gene Gln223Arg polymorphism and type 2 diabetes mellitus: a metaanalysis of 3367 subjects

https://doi.org/10.18632/oncotarget.18720
61927-61934
Abstract  |  PDF  |  Full Text  |  How to cite

Synergistic interaction between galectin3 and carcinoembryonic antigen promotes colorectal cancer metastasis

https://doi.org/10.18632/oncotarget.18721
61935-61943
Abstract  |  PDF  |  Full Text  |  How to cite

Serinearginine protein kinase 1 SRPK1 is elevated in gastric cancer and plays oncogenic functions

https://doi.org/10.18632/oncotarget.18734
61944-61957
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Swine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway

https://doi.org/10.18632/oncotarget.18740
61958-61968
Abstract  |  PDF  |  Full Text  |  How to cite

Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of protumorigenic factors

https://doi.org/10.18632/oncotarget.18755
61969-61981
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Chiral platinum II423dihydroxypropyl formamide oxoaporphine FOA complexes promote tumor cells apoptosis by directly targeting Gquadruplex DNA in vitro and in vivo

https://doi.org/10.18632/oncotarget.18778
61982-61997
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Docking of CDK1 with antibiotic drugs revealed novel therapeutic value in breast ductal cancer in situ

https://doi.org/10.18632/oncotarget.18779
61998-62010
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of CD14 as a potential biomarker of hepatocellular carcinoma using iTRAQ quantitative proteomics

https://doi.org/10.18632/oncotarget.18782
62011-62028
Abstract  |  PDF  |  Full Text  |  How to cite

Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers

https://doi.org/10.18632/oncotarget.18790
62029-62038
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antihyperglycemic treatment in patients with type 2 diabetes in Italy: the impact of age and kidney function

https://doi.org/10.18632/oncotarget.18816
62039-62048
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Human colorectal cancer cells induce vascular smooth muscle cell apoptosis in an exocrine manner

https://doi.org/10.18632/oncotarget.18893
62049-62056
Abstract  |  PDF  |  Full Text  |  How to cite

Redoxdependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin

https://doi.org/10.18632/oncotarget.18907
62057-62068
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TRIM22 confers poor prognosis and promotes epithelialmesenchymal transition through regulation of AKT/GSK3β/βcatenin signaling in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.18911
62069-62080
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survival

https://doi.org/10.18632/oncotarget.19060
62081-62098
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Altered microRNAs expression in T cells of patients with SLE involved in the lack of vitamin D

https://doi.org/10.18632/oncotarget.19062
62099-62110
Abstract  |  PDF  |  Full Text  |  How to cite

A patientderived orthotopic xenograft PDOX mouse model of a cisplatinumresistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology

https://doi.org/10.18632/oncotarget.19095
62111-62119
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of Notch1 pathway is involved in rottlerininduced tumor suppressive function in nasopharyngeal carcinoma cells

https://doi.org/10.18632/oncotarget.19097
62120-62130
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibitor of H3K27 demethylase JMJD3/UTX GSKJ4 is a potential therapeutic option for castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.19100
62131-62142
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR217 inhibits laryngeal cancer metastasis by repressing AEG1 and PDL1 expression

https://doi.org/10.18632/oncotarget.19121
62143-62153
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Shuanghuang Shengbai granule cures myelosuppression and suppresses lung cancer progression: mechanism and therapeutic targets from the aspect of microRNAs

https://doi.org/10.18632/oncotarget.19129
62154-62166
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of the E2F target gene CENPI promotes chromosome instability and predicts poor prognosis in estrogen receptorpositive breast cancer

https://doi.org/10.18632/oncotarget.19131
62167-62182
Abstract  |  PDF  |  Full Text  |  How to cite

The regulation of hydroxysteroid 17βdehydrogenase type 1 and 2 gene expression in breast cancer cell lines by estradiol dihydrotestosterone microRNAs and genes related to breast cancer

https://doi.org/10.18632/oncotarget.19136
62183-62194
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of miR135b5p promotes unfavorable clinical characteristics and poor prognosis via the repression of SFRP4 in pancreatic cancer

https://doi.org/10.18632/oncotarget.19150
62195-62207
Abstract  |  PDF  |  Full Text  |  How to cite

High Eg5 expression predicts poor prognosis in breast cancer

https://doi.org/10.18632/oncotarget.19215
62208-62216
Abstract  |  PDF  |  Full Text  |  How to cite

CTCF promotes epithelial ovarian cancer metastasis by broadly controlling the expression of metastasisassociated genes

https://doi.org/10.18632/oncotarget.19216
62217-62230
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pathologic lymph node ratio is a predictor of esophageal carcinoma patient survival: a literaturebased pooled analysis

https://doi.org/10.18632/oncotarget.19258
62231-62239
Abstract  |  PDF  |  Full Text  |  How to cite

CCNE1 expression in high grade serous carcinoma does not correlate with chemoresistance

https://doi.org/10.18632/oncotarget.19272
62240-62247
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Periostin promotes epithelialmesenchymal transition via the MAPK/miR381 axis in lung cancer

https://doi.org/10.18632/oncotarget.19273
62248-62260
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The influence of marital status on the survival of patients with esophageal cancer: a populationbased propensitymatched study

https://doi.org/10.18632/oncotarget.19446
62261-62273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Utility of gene methylation analysis cytological examination and HPV16/18 genotyping in triage of highrisk human papilloma viruspositive women

https://doi.org/10.18632/oncotarget.19459
62274-62285
Abstract  |  PDF  |  Full Text  |  How to cite

Genetic polymorphisms of long noncoding RNA GAS5 predict platinumbased concurrent chemoradiotherapy response in nasopharyngeal carcinoma patients

https://doi.org/10.18632/oncotarget.19725
62286-62297
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination of bone marrow mesenchymal stem cells sheet and platelet rich plasma for posterolateral lumbar fusion

https://doi.org/10.18632/oncotarget.19749
62298-62311
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

Tumorinfiltrating immune cells and prognosis in gastric cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17602
62312-62329
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis comparing the efficacy of nedaplatinbased regimens between squamous cell and nonsquamous cell lung cancers

https://doi.org/10.18632/oncotarget.17499
62330-62338
Abstract  |  PDF  |  Full Text  |  How to cite

Is FOLFOXIRI alone or combined with targeted therapy administered as firstline treatment a reasonable choice for most patients with mCRC Systematic review and network metaanalysis

https://doi.org/10.18632/oncotarget.17725
62339-62348
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic significance of antidiabetic medications in pancreatic cancer: A metaanalysis

https://doi.org/10.18632/oncotarget.17728
62349-62357
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Occupational ultraviolet exposure and risk of nonHodgkin's lymphomas: a metaanalysis

https://doi.org/10.18632/oncotarget.18140
62358-62370
Abstract  |  PDF  |  Full Text  |  How to cite

Colorectal adenoma recurrence rates among postpolypectomy patients in the placebocontrolled groups of randomized clinical trials: a metaanalysis

https://doi.org/10.18632/oncotarget.18181
62371-62381
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of three promoter polymorphisms in interleukin10 gene with cancer susceptibility in the Chinese population: a metaanalysis

https://doi.org/10.18632/oncotarget.18220
62382-62399
Abstract  |  PDF  |  Full Text  |  How to cite

Correlation between estrogen receptor expression and prognosis in epithelial ovarian cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.18253
62400-62413
Abstract  |  PDF  |  Full Text  |  How to cite

A metaanalysis of Hashimoto’s thyroiditis and papillary thyroid carcinoma risk

https://doi.org/10.18632/oncotarget.18620
62414-62424
Abstract  |  PDF  |  Full Text  |  How to cite

Statin use and endometrial cancer risk: a metaanalysis

https://doi.org/10.18632/oncotarget.18658
62425-62434
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of the efficacy of treatments for newly diagnosed and relapsed/refractory multiple myeloma with del17p

https://doi.org/10.18632/oncotarget.18722
62435-62444
Abstract  |  PDF  |  Full Text  |  How to cite

Association between LMP2/LMP7 genetic variability and cancer susceptibility especially among Asians: evidence from a metaanalysis

https://doi.org/10.18632/oncotarget.18752
62445-62453
Abstract  |  PDF  |  Full Text  |  How to cite

Long noncoding RNA TUG1 as a potential prognostic biomarker in human cancers: a metaanalysis

https://doi.org/10.18632/oncotarget.19099
62454-62462
Abstract  |  PDF  |  Full Text  |  How to cite

Association between TGFB1 genetic polymorphisms and chronic allograft dysfunction: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19516
62463-62469
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic value of long non coding RNAs in cervical cancer: A metaanalysis

https://doi.org/10.18632/oncotarget.17620
62470-62477
Abstract  |  PDF  |  Full Text  |  How to cite

Increased mortality for colorectal cancer patients with preexisting diabetes mellitus: an updated metaanalysis

https://doi.org/10.18632/oncotarget.19923
62478-62488
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Reduced Ecadherin expression is correlated with poor prognosis in patients with bladder cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19934
62489-62499
Abstract  |  PDF  |  Full Text  |  How to cite

Metaanalysis of associations between telomere length and colorectal cancer survival from observational studies

https://doi.org/10.18632/oncotarget.20055
62500-62507
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic polymorphisms of noncoding RNAs associated with increased head and neck cancer susceptibility: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.20096
62508-62523
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinicopathological and prognostic significance of circulating tumor cells in patients with lung cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.19122
62524-62536
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic and clinicopathological significance of SIRT1 expression in NSCLC: a metaanalysis

https://doi.org/10.18632/oncotarget.19244
62537-62544
Abstract  |  PDF  |  Full Text  |  How to cite

Antihypertensive drug use and breast cancer risk: a metaanalysis of observational studies

https://doi.org/10.18632/oncotarget.19117
62545-62560
Abstract  |  PDF  |  Full Text  |  How to cite

A metaanalysis of transcriptomic characterization revealed extracellular matrix pathway involved in the H5N1 and H7N9 infections

https://doi.org/10.18632/oncotarget.19315
62561-62572
Abstract  |  PDF  |  Full Text  |  How to cite

CD147 as a novel biomarker for predicting the prognosis and clinicopathological features of bladder cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.19257
62573-62588
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Metaanalysis of SIRT1 expression as a prognostic marker for overall survival in gastrointestinal cancer

https://doi.org/10.18632/oncotarget.19880
62589-62599
Abstract  |  PDF  |  Full Text  |  How to cite

Clinical Research Papers

Mean platelet volume platelet distribution width and carcinoembryonic antigen to discriminate gastric cancer from gastric ulcer

https://doi.org/10.18632/oncotarget.15898
62600-62605
Abstract  |  PDF  |  Full Text  |  How to cite

Multiparametric imaging using 18FFDG PET/CT heterogeneity parameters and functional MRI techniques: prognostic significance in patients with primary advanced oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiotherapy

https://doi.org/10.18632/oncotarget.15904
62606-62621
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Postoperative fever predicts poor prognosis of gastric cancer

https://doi.org/10.18632/oncotarget.15979
62622-62629
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic clinicopathologic factors in carcinoma of unknown primary origin: a study of 106 consecutive cases

https://doi.org/10.18632/oncotarget.16021
62630-62640
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical features and prognosis for intraventricular liponeurocytoma

https://doi.org/10.18632/oncotarget.16024
62641-62647
Abstract  |  PDF  |  Full Text  |  How to cite

Addition of bevacizumab for malignant pleural effusion as the manifestation of acquired EGFRTKI resistance in NSCLC patients

https://doi.org/10.18632/oncotarget.16061
62648-62657
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The effects of intra and postoperative anaesthesia and analgesia choice on outcome after gastric cancer resection: a retrospective study

https://doi.org/10.18632/oncotarget.16724
62658-62665
Abstract  |  PDF  |  Full Text  |  How to cite

Impact of marital status during diagnosis on cancercaused specific survival in acute myeloid leukemia patients: a casecontrol and populationbased study

https://doi.org/10.18632/oncotarget.16989
62666-62680
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic value of neutrophiltolymphocyte ratio in urothelial carcinoma of the upper urinary tract and bladder: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.17467
62681-62692
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effects of liraglutide on hemodynamic parameters in patients with heart failure

https://doi.org/10.18632/oncotarget.18570
62693-62702
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Poolinganalysis for diagnostic and prognostic value of MiRNA100 in various cancers

https://doi.org/10.18632/oncotarget.18697
62703-62715
Abstract  |  PDF  |  Full Text  |  How to cite

Techniques for detecting chromosomal aberrations in myelodysplastic syndromes

https://doi.org/10.18632/oncotarget.17698
62716-62729
Abstract  |  PDF  |  Full Text  |  How to cite

Driving better and safer HER2specific CARs for cancer therapy

https://doi.org/10.18632/oncotarget.17528
62730-62741
Abstract  |  PDF  |  Full Text  |  How to cite

Improving radiotherapy in cancer treatment: Promises and challenges

https://doi.org/10.18632/oncotarget.18409
62742-62758
Abstract  |  PDF  |  Full Text  |  How to cite

Interplay between apoptosis and autophagy in colorectal cancer

https://doi.org/10.18632/oncotarget.18663
62759-62768
Abstract  |  PDF  |  Full Text  |  How to cite

Metaanalysis showing that ERCC1 polymorphism is predictive of osteosarcoma prognosis

https://doi.org/10.18632/oncotarget.19370
62769-62779
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AMPK: a novel target for treating hepatic fibrosis

https://doi.org/10.18632/oncotarget.19376
62780-62792
Abstract  |  PDF  |  Full Text  |  How to cite

The molecular basis of targeting PFKFB3 as a therapeutic strategy against cancer

https://doi.org/10.18632/oncotarget.19513
62793-62802
Abstract  |  PDF  |  Full Text  |  How to cite

Exosomal tetraspanins mediate cancer metastasis by altering host microenvironment

https://doi.org/10.18632/oncotarget.19119
62803-62815
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Metabolic syndrome endocrine disruptors and prostate cancer associations: biochemical and pathophysiological evidences

https://doi.org/10.18632/oncotarget.20631
62816-62816
Correction  |  PDF  |  How to cite

Correction: Genomic mutationdriven metastatic breast cancer therapy: a single center experience

https://doi.org/10.18632/oncotarget.20632
62817-62817
Correction  |  PDF  |  How to cite


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