Oncotarget

VOLUME 8 (2017)

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About The Cover

The cover for issue 59 of Oncotarget features Figure 4A, "Knockdown of Glut-1 expression by siGlut-1 was verified by immunofluorescent staining in tumor cells after 48 h. The nuclei of tumor cells were counter-stained with DAPI," from Dai, et al.

Table of Contents

Editorial

Liraglutide: another reason to target prediabetes

https://doi.org/10.18632/oncotarget.22256
99203-99204
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TGFβ activates PI3KAKT signaling <i>via</i> TRAF6

https://doi.org/10.18632/oncotarget.22275
99205-99206
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Therapeutic induction of high endothelial venules HEVs to enhance Tcell infiltration in tumors

https://doi.org/10.18632/oncotarget.22276
99207-99208
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T cells in chronic lymphocytic leukemia: can they fight

https://doi.org/10.18632/oncotarget.22277
99209-99210
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SNPs for breast cancer risk assessment

https://doi.org/10.18632/oncotarget.22278
99211-99212
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Linking dental pathologies and cancer <i>via</i> Wnt signalling

https://doi.org/10.18632/oncotarget.22281
99213-99214
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MEK/ERK addiction in CNL/aCML

https://doi.org/10.18632/oncotarget.22283
99215-99216
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The ascorbate transporter SVCT2 to target microgliadependent inflammation

https://doi.org/10.18632/oncotarget.22306
99217-99218
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Elagolix: a promising oral GnRH antagonist for endometriosisassociated pain

https://doi.org/10.18632/oncotarget.22381
99219-99220
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Progress and criticalities in the management of acute promyelocytic leukemia

https://doi.org/10.18632/oncotarget.22385
99221-99222
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Research Perspectives

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity

https://doi.org/10.18632/oncotarget.21834
99223-99236
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Priority Research Papers

Comparative analysis of primary <i>versus</i> relapse/refractory DLBCL identifies shifts in mutation spectrum

https://doi.org/10.18632/oncotarget.18502
99237-99244
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel smallmolecule arylsulfonamide causes energetic stress and suppresses breast and lung tumor growth and metastasis

https://doi.org/10.18632/oncotarget.22104
99245-99260
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Priority Research Papers: Gerotarget

Constitutive Cyclin O deficiency results in penetrant hydrocephalus impaired growth and infertility

https://doi.org/10.18632/oncotarget.21818
99261-99273
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

GULP1/CED6 ameliorates amyloidβ toxicity in a <i>Drosophila</i> model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.20062
99274-99283
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Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing

https://doi.org/10.18632/oncotarget.21849
99284-99295
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

COX2 metabolic products the prostaglandin I<sub>2</sub> and F<sub>2α</sub> mediate the effects of TNFα and Zn<sup>2+</sup> in stimulating the phosphorylation of Tau

https://doi.org/10.18632/oncotarget.21853
99296-99311
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Research Papers: Immunology

Deep sequencing of the T cell receptor β repertoire reveals signature patterns and clonal drift in atherosclerotic plaques and patients

https://doi.org/10.18632/oncotarget.19892
99312-99322
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Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander <i>Andrias davidianus</i>

https://doi.org/10.18632/oncotarget.21470
99323-99335
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The sexist behaviour of immune checkpoint inhibitors in cancer therapy

https://doi.org/10.18632/oncotarget.22242
99336-99346
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Research Papers

Effects of nicorandil on PI3K/Akt signaling pathway and its antiapoptotic mechanisms in coronary microembolization in rats

https://doi.org/10.18632/oncotarget.19966
99347-99358
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Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACEinduced hypoxia: A biopsy and resection matched study

https://doi.org/10.18632/oncotarget.22078
99359-99371
Abstract  |  PDF  |  Full Text  |  How to cite

Predictive relevance of PDL1 expression with preexisting TILs in gastric cancer

https://doi.org/10.18632/oncotarget.22079
99372-99381
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of aldehyde dehydrogenase 1 enhances the cytotoxic effect of retinaldehyde on A549 cancer cells

https://doi.org/10.18632/oncotarget.19544
99382-99393
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The prognostic value of overexpressed TrkB in solid tumors: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19561
99394-99401
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis

https://doi.org/10.18632/oncotarget.19660
99402-99413
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Combination of AQP1 and &#x03B2;catenin expression is an independent prognosis factor in astrocytoma patients

https://doi.org/10.18632/oncotarget.19562
99414-99428
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Epidermal growth factor receptor T790M mutation as a prognostic factor in EGFRmutant nonsmall cell lung cancer patients that acquired resistance to EGFR tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.19681
99429-99437
Abstract  |  PDF  |  Full Text  |  How to cite

Radiotherapy for stage IIA rectal cancer may not benefit all

https://doi.org/10.18632/oncotarget.19683
99438-99450
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Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

https://doi.org/10.18632/oncotarget.19807
99451-99469
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Laminarin counteracts dietinduced obesity associated with glucagonlike peptide1 secretion

https://doi.org/10.18632/oncotarget.19957
99470-99481
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Inhibition of ZEB1 leads to inversion of metastatic characteristics and restoration of paclitaxel sensitivity of chronic chemoresistant ovarian carcinoma cells

https://doi.org/10.18632/oncotarget.20107
99482-99494
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Interleukin13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization

https://doi.org/10.18632/oncotarget.20111
99495-99503
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Icariin induces cell differentiation and cell cycle arrest in mouse melanoma B16 cells via Erk1/2p38JNKdependent pathway

https://doi.org/10.18632/oncotarget.20118
99504-99513
Abstract  |  PDF  |  Full Text  |  How to cite

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis

https://doi.org/10.18632/oncotarget.20577
99514-99530
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Aflatoxin B<sub>1</sub> affects apoptosis and expression of death receptor and endoplasmic reticulum molecules in chicken spleen

https://doi.org/10.18632/oncotarget.20595
99531-99540
Abstract  |  PDF  |  Full Text  |  How to cite

Regional lymph node involvement and outcomes in appendiceal neuroendocrine tumors: a SEER database analysis

https://doi.org/10.18632/oncotarget.20362
99541-99551
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis

https://doi.org/10.18632/oncotarget.20601
99552-99566
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

RUNX1 promote invasiveness in pancreatic ductal adenocarcinoma through regulating miR93

https://doi.org/10.18632/oncotarget.20433
99567-99579
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Histopathological expression analysis of intercellular adhesion molecule 1 ICAM1 along development and progression of human melanoma

https://doi.org/10.18632/oncotarget.20884
99580-99586
Abstract  |  PDF  |  Full Text  |  How to cite

Prognostic significance of total metabolic tumor volume on <sup>18</sup>Ffluorodeoxyglucose positron emission tomography/ computed tomography in patients with diffuse large Bcell lymphoma receiving rituximabcontaining chemotherapy

https://doi.org/10.18632/oncotarget.20447
99587-99600
Abstract  |  PDF  |  Full Text  |  How to cite

A bioinformaticstoclinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology

https://doi.org/10.18632/oncotarget.20448
99601-99611
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Myocardin and Stat3 act synergistically to inhibit cardiomyocyte apoptosis

https://doi.org/10.18632/oncotarget.20450
99612-99623
Abstract  |  PDF  |  Full Text  |  How to cite

Harnessing the heart’s resistance to malignant tumors: cardiacderived extracellular vesicles decrease fibrosarcoma growth and leukemiarelated mortality in rodents

https://doi.org/10.18632/oncotarget.20454
99624-99636
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The quinonebased derivative HMNQ induces apoptotic and autophagic cell death by modulating reactive oxygen species in cancer cells

https://doi.org/10.18632/oncotarget.21005
99637-99648
Abstract  |  PDF  |  Full Text  |  How to cite

Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation <i>in vitro</i> and <i>in vivo</i>

https://doi.org/10.18632/oncotarget.20587
99649-99665
Abstract  |  PDF  |  Full Text  |  How to cite

Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

https://doi.org/10.18632/oncotarget.20649
99666-99680
Abstract  |  PDF  |  Full Text  |  How to cite

mir193 targets ALDH2 and contributes to toxic aldehyde accumulation and tyrosine hydroxylase dysfunction in cerebral ischemia/reperfusion injury

https://doi.org/10.18632/oncotarget.21129
99681-99692
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Apolipoprotein AI mimetic peptide 4F suppresses tumorassociated macrophages and pancreatic cancer progression

https://doi.org/10.18632/oncotarget.21157
99693-99706
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of MMP2 RB and PAI1 with decreased recurrencefree survival and overall survival in bladder cancer patients

https://doi.org/10.18632/oncotarget.20686
99707-99721
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Podocalyxin promotes proliferation and survival in mature Bcell nonHodgkin lymphoma cells

https://doi.org/10.18632/oncotarget.21283
99722-99739
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NLRP3inflammasome inhibition prevents high fat and high sugar dietsinduced heart damage through autophagy induction

https://doi.org/10.18632/oncotarget.20763
99740-99756
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR195 suppresses the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by inhibiting YAP

https://doi.org/10.18632/oncotarget.20909
99757-99771
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of hub genes related to siliconeinduced immune response in rats

https://doi.org/10.18632/oncotarget.21546
99772-99783
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mesenchymal stem cells inhibit T cell activation by releasing TGFβ1 from TGFβ1/GARP complex

https://doi.org/10.18632/oncotarget.21549
99784-99800
Abstract  |  PDF  |  Full Text  |  How to cite

Tumorassociated macrophages promote tumor metastasis via the TGF&#x03B2;/SOX9 axis in nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.21068
99801-99815
Abstract  |  PDF  |  Full Text  |  How to cite

R383C mutation of human CDC20 results in idiopathic nonobstructive azoospermia

https://doi.org/10.18632/oncotarget.21071
99816-99824
Abstract  |  PDF  |  Full Text  |  How to cite

Saikosaponind a calcium mobilizing agent sensitizes chemoresistant ovarian cancer cells to cisplatininduced apoptosis by facilitating mitochondrial fission and G2/M arrest

https://doi.org/10.18632/oncotarget.21076
99825-99840
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extracellular vesicles from KSHVinfected endothelial cells activate the complement system

https://doi.org/10.18632/oncotarget.21668
99841-99860
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Highsensitivity modified Glasgow prognostic score HSmGPS Is superior to the mGPS in esophageal cancer patients treated with chemoradiotherapy

https://doi.org/10.18632/oncotarget.21734
99861-99870
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR4835p promotes IGFII transcription and is associated with poor prognosis of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.21737
99871-99888
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

ALVJ infection induces chicken monocyte death accompanied with the production of IL1β and IL18

https://doi.org/10.18632/oncotarget.21906
99889-99900
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PD1/PDL1 interaction upregulates MDR1/Pgp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways

https://doi.org/10.18632/oncotarget.21914
99901-99912
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Functional profiling of microtumors to identify cancer associated fibroblastderived drug targets

https://doi.org/10.18632/oncotarget.21915
99913-99930
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antioxidant MMCC ameliorates catchup growth related metabolic dysfunction

https://doi.org/10.18632/oncotarget.21965
99931-99939
Abstract  |  PDF  |  Full Text  |  How to cite

Construction of a model predicting the risk of tube feeding intolerance after gastrectomy for gastric cancer based on 225 cases from a single Chinese center

https://doi.org/10.18632/oncotarget.21966
99940-99949
Abstract  |  PDF  |  Full Text  |  How to cite

The humanized antihuman AMHRII mAb 3C23K exerts an antitumor activity against human ovarian cancer through tumorassociated macrophages

https://doi.org/10.18632/oncotarget.21556
99950-99965
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

https://doi.org/10.18632/oncotarget.21557
99966-99977
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tamoxifen sensitivityrelated microRNA342 is a useful biomarker for breast cancer survival

https://doi.org/10.18632/oncotarget.21577
99978-99989
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Salivary miRNA panel to detect HPVpositive and HPVnegative head and neck cancer patients

https://doi.org/10.18632/oncotarget.21725
99990-100001
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Combination therapy of exendin4 and allogenic adiposederived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats

https://doi.org/10.18632/oncotarget.21727
100002-100020
Abstract  |  PDF  |  Full Text  |  How to cite

Glipizide sensitizes lung cancer cells to TRAILinduced apoptosis via Akt/mTOR/autophagy pathways

https://doi.org/10.18632/oncotarget.21754
100021-100033
Abstract  |  PDF  |  Full Text  |  How to cite

Apelin protects against myocardial ischemic injury by inhibiting dynaminrelated protein 1

https://doi.org/10.18632/oncotarget.21777
100034-100044
Abstract  |  PDF  |  Full Text  |  How to cite

Low concentration of formononetin promotes proliferation of estrogen receptorpositive cells through an ER&#x03B1;miR375PTENERK1/2bcl2 pathway

https://doi.org/10.18632/oncotarget.21923
100045-100055
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Survival outcomes of double and triplesequential targeted therapy in patients with metastatic renal cell carcinoma: a retrospective comparison

https://doi.org/10.18632/oncotarget.21926
100056-100065
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Proteome profiling of clear cell renal cell carcinoma in von HippelLindau patients highlights upregulation of XaaPro aminopeptidase1 an antiproliferative and antimigratory exoprotease

https://doi.org/10.18632/oncotarget.21929
100066-100078
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations between <i>HVEM/LIGHT/BTLA/CD160</i> polymorphisms and the occurrence of antibodymediate rejection in renal transplant recipients

https://doi.org/10.18632/oncotarget.21941
100079-100094
Abstract  |  PDF  |  Full Text  |  How to cite

Identification of potential metabolic biomarkers of cerebrospinal fluids that differentiate tuberculous meningitis from other types of meningitis by a metabolomics study

https://doi.org/10.18632/oncotarget.21942
100095-100112
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Phenformin has antitumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer

https://doi.org/10.18632/oncotarget.22012
100113-100127
Abstract  |  PDF  |  Full Text  |  How to cite

The aldehyde group of gossypol induces mitochondrial apoptosis via ROSSIRT1p53PUMA pathway in male germline stem cell

https://doi.org/10.18632/oncotarget.22044
100128-100140
Abstract  |  PDF  |  Full Text  |  How to cite

Digenic mutations on <i>SCAP</i> and <i>AGXT2</i> predispose to premature myocardial infarction

https://doi.org/10.18632/oncotarget.22045
100141-100149
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Genetic predisposition to ischaemic stroke by <i>RAGE</i> and <i>HMGB1</i> gene variants in Chinese Han population

https://doi.org/10.18632/oncotarget.22112
100150-100164
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Associations of tumor regression grade with outcomes in patients with locally advanced rectal cancer treated with preoperative twoweek course of radiotherapy

https://doi.org/10.18632/oncotarget.22118
100165-100175
Abstract  |  PDF  |  Full Text  |  How to cite

Decreased expression of interferoninduced protein 2 IFIT2 by Wnt/&#x03B2;catenin signaling confers antiapoptotic properties to colorectal cancer cells

https://doi.org/10.18632/oncotarget.22122
100176-100186
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Calcitriol induces cell senescence of kidney cancer through JMJD3 mediated histone demethylation

https://doi.org/10.18632/oncotarget.22124
100187-100195
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Systematic analysis of the expression profile of noncoding RNAs involved in ischemia/reperfusioninduced acute kidney injury in mice using RNA sequencing

https://doi.org/10.18632/oncotarget.22130
100196-100215
Abstract  |  PDF  |  Full Text  |  How to cite

Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3NF&#x03BA;B signaling

https://doi.org/10.18632/oncotarget.22145
100216-100226
Abstract  |  PDF  |  Full Text  |  How to cite

MicroRNA433 inhibits oral squamous cell carcinoma cells by targeting FAK

https://doi.org/10.18632/oncotarget.22151
100227-100241
Abstract  |  PDF  |  Full Text  |  How to cite

Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2 phosphoERK1/2 and Dickkopf Wnt signaling pathway inhibitor DKK3

https://doi.org/10.18632/oncotarget.22152
100242-100260
Abstract  |  PDF  |  Full Text  |  How to cite

<i>MAPK</i> and <i>ERK</i> polymorphisms are associated with PCOS risk in Chinese women

https://doi.org/10.18632/oncotarget.22153
100261-100268
Abstract  |  PDF  |  Full Text  |  How to cite

Gsdma3 regulates hair follicle differentiation via Wnt5amediated noncanonical Wnt signaling pathway

https://doi.org/10.18632/oncotarget.22212
100269-100279
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The cancertestis antigen sperm protein 17 a new biomarker and immunological target in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.22213
100280-100287
Abstract  |  PDF  |  Full Text  |  How to cite

Chronic kidney disease is associated with a risk of higher mortality following total knee arthroplasty in diabetic patients: a nationwide populationbased study

https://doi.org/10.18632/oncotarget.22215
100288-100295
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer

https://doi.org/10.18632/oncotarget.22220
100296-100311
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

An antiCAPN5 intracellular antibody acts as an inhibitor of CAPN5mediated neuronal degeneration

https://doi.org/10.18632/oncotarget.22221
100312-100325
Abstract  |  PDF  |  Full Text  |  How to cite

Cotargeting aurora kinase with PDL1 and PI3K abrogates immune checkpoint mediated proliferation in peripheral Tcell lymphoma: a novel therapeutic strategy

https://doi.org/10.18632/oncotarget.22222
100326-100338
Abstract  |  PDF  |  Full Text  |  How to cite

Endothelialderived interleukin6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

https://doi.org/10.18632/oncotarget.22225
100339-100352
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Serum corin is associated with the risk of chronic heart failure

https://doi.org/10.18632/oncotarget.22227
100353-100357
Abstract  |  PDF  |  Full Text  |  How to cite

Kr&#x00FC;ppellike factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling

https://doi.org/10.18632/oncotarget.22229
100358-100370
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Effect of dexmedetomidine infusion for intravenous patientcontrolled analgesia on the quality of recovery after laparotomy surgery

https://doi.org/10.18632/oncotarget.22232
100371-100383
Abstract  |  PDF  |  Full Text  |  How to cite

Plasma proteomics reveals coagulation inflammation and metabolic shifts in Htype hypertension patients with and without acute ischemic stroke

https://doi.org/10.18632/oncotarget.22233
100384-100395
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Hydrogen sulfide attenuates chronic restrain stressinduced cognitive impairment by upreglulation of Sirt1 in hippocampus

https://doi.org/10.18632/oncotarget.22237
100396-100410
Abstract  |  PDF  |  Full Text  |  How to cite

Alcohol intake aggravates adipose browning and muscle atrophy in cancerassociated cachexia

https://doi.org/10.18632/oncotarget.22243
100411-100420
Abstract  |  PDF  |  Full Text  |  How to cite

CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease

https://doi.org/10.18632/oncotarget.22244
100421-100432
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Caspase4 is essential for saikosaponin ainduced apoptosis acting upstream of caspase2 and &#x03B3;H2AX in colon cancer cells

https://doi.org/10.18632/oncotarget.22247
100433-100448
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Meta-Analysis

The impact of metformin use on survival in prostate cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22117
100449-100458
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HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a metaanalysis

https://doi.org/10.18632/oncotarget.19682
100459-100468
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Comparison of efficacy between brachytherapy and penectomy in patients with penile cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.18761
100469-100477
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Clinicopathological and prognostic significance of HMGA2 overexpression in gastric cancer: a metaanalysis

https://doi.org/10.18632/oncotarget.19001
100478-100489
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Prognostic role of long noncoding RNA ZFAS1 in cancer patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.19162
100490-100498
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Prognostic role of long noncoding RNA TUG1 expression in various cancers: a metaanalysis

https://doi.org/10.18632/oncotarget.20037
100499-100507
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

What is the best combination treatment with transarterial chemoembolization of unresectable hepatocellular carcinoma a systematic review and network metaanalysis

https://doi.org/10.18632/oncotarget.20119
100508-100523
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Effects of levosimendan on mortality in patients with septic shock: systematic review with metaanalysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.20123
100524-100532
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Long noncoding RNAs for osteosarcoma in the mouse: a metaanalysis

https://doi.org/10.18632/oncotarget.20128
100533-100544
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Increased DCLK1 correlates with the malignant status and poor outcome in malignant tumors: a metaanalysis

https://doi.org/10.18632/oncotarget.20129
100545-100557
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Association of <i>PPARG</i> rs 1801282 C>G polymorphism with risk of colorectal cancer: from a casecontrol study to a metaanalysis

https://doi.org/10.18632/oncotarget.20138
100558-100569
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Smoking and risk of cholangiocarcinoma: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.20141
100570-100581
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Exogenous melatonin in the treatment of pain: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.21504
100582-100592
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Comprehensive assessment of association between TLR4 gene polymorphisms and cancer risk: a systematic metaanalysis

https://doi.org/10.18632/oncotarget.21543
100593-100602
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Potassium measurements and risk of type 2 diabetes: a doseresponse metaanalysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.21823
100603-100613
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Significance of Ki67 in nonmuscle invasive bladder cancer patients: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.21899
100614-100630
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Diagnostic prediction of urinary [TIMP2] x [IGFBP7] for acute kidney injury: A metaanalysis exploring detection time and cutoff levels

https://doi.org/10.18632/oncotarget.21903
100631-100639
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Effect of hyperthermic intrathoracic chemotherapy on the malignant pleural mesothelioma: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22062
100640-100647
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Evaluation of the NMP22 BladderChek test for detecting bladder cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22065
100648-100656
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The efficacy and safety of different pharmacological interventions for patients with advanced biliary tract cancer: A network metaanalysis

https://doi.org/10.18632/oncotarget.20445
100657-100667
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Network metaanalysis of the efficacy of firstline chemotherapy regimens in patients with advanced colorectal cancer

https://doi.org/10.18632/oncotarget.22177
100668-100677
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Clinical Research Papers

Characterization of the urinary microbiota of elderly women and the effects of type 2 diabetes and urinary tract infections on the microbiota

https://doi.org/10.18632/oncotarget.21126
100678-100690
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The protective effect of PFT&#x03B1; on alcoholinduced osteonecrosis of the femoral head

https://doi.org/10.18632/oncotarget.19160
100691-100707
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Outcome of oligoprogressing metastatic renal cell carcinoma patients treated with locoregional therapy: a multicenter retrospective analysis

https://doi.org/10.18632/oncotarget.20022
100708-100716
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Congenital heart defects of fetus after maternal exposure to organic and inorganic environmental factors: a cohort study

https://doi.org/10.18632/oncotarget.20110
100717-100723
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Optimal treatment strategies for clinically suspicious lateral pelvic lymph node metastasis in rectal cancer

https://doi.org/10.18632/oncotarget.20121
100724-100733
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Efficacy and safety of apatinib combined with transarterial chemoembolization for hepatocellular carcinoma with portal venous tumor thrombus: a retrospective study

https://doi.org/10.18632/oncotarget.20140
100734-100745
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Preoperative radiotherapy for patients with rectal cancer: a risk factor for nonreversal of ileostomy caused by stenosis or stiffness proximal to colorectal anastomosis

https://doi.org/10.18632/oncotarget.20602
100746-100753
Abstract  |  PDF  |  Full Text  |  How to cite

Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study

https://doi.org/10.18632/oncotarget.21736
100754-100763
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Neoadjuvant chemotherapy with different dose regimens of docetaxel cisplatin and fluorouracil TPF for locoregionally advanced nasopharyngeal carcinoma: a retrospective study

https://doi.org/10.18632/oncotarget.21992
100764-100772
Abstract  |  PDF  |  Full Text  |  How to cite

Ovarian stimulated cycle: not a better alternative for women without ovulation disorder in intrauterine insemination

https://doi.org/10.18632/oncotarget.22052
100773-100780
Abstract  |  PDF  |  Full Text  |  How to cite

Reviews

Tumorderived exosomes in colorectal cancer progression and their clinical applications

https://doi.org/10.18632/oncotarget.20117
100781-100790
Abstract  |  PDF  |  Full Text  |  How to cite

Does primary tumor location impact the prognosis of colorectal liver metastases patients after microwave ablation Lessons from 10 years’ experience

https://doi.org/10.18632/oncotarget.18764
100791-100800
Abstract  |  PDF  |  Full Text  |  How to cite

Comparison of crossplatform technologies for EGFR T790M testing in patients with nonsmall cell lung cancer

https://doi.org/10.18632/oncotarget.19007
100801-100818
Abstract  |  PDF  |  Full Text  |  How to cite

miRNA and lncRNA as biomarkers in cholangiocarcinomaCCA

https://doi.org/10.18632/oncotarget.19044
100819-100830
Abstract  |  PDF  |  Full Text  |  How to cite

Circulating biomarkers in osteosarcoma: new translational tools for diagnosis and treatment

https://doi.org/10.18632/oncotarget.19852
100831-100851
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Recent advances on uric acid transporters

https://doi.org/10.18632/oncotarget.20135
100852-100862
Abstract  |  PDF  |  Full Text  |  How to cite

Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry IHC or fluorescence <i>in situ</i> hybridization FISH to select the optimal patients for matched therapy

https://doi.org/10.18632/oncotarget.19809
100863-100898
Abstract  |  PDF  |  Full Text  |  How to cite

The role of microbiota in the pathogenesis of schizophrenia and major depressive disorder and the possibility of targeting microbiota as a treatment option

https://doi.org/10.18632/oncotarget.21284
100899-100907
Abstract  |  PDF  |  Full Text  |  How to cite

Venombased peptide therapy: insights into anticancer mechanism

https://doi.org/10.18632/oncotarget.21740
100908-100930
Abstract  |  PDF  |  Full Text  |  How to cite

A molecular view of the radioresistance of gliomas

https://doi.org/10.18632/oncotarget.21753
100931-100941
Abstract  |  PDF  |  Full Text  |  How to cite

Case Reports

A rare case of esophageal metastasis from pancreatic ductal adenocarcinoma: a case report and literature review

https://doi.org/10.18632/oncotarget.18458
100942-100950
Abstract  |  PDF  |  Full Text  |  How to cite

Meeting Reports

Results and prospects of development of new polyphenolic drugs for cancer patients

https://doi.org/10.18632/oncotarget.22307
100951-100956
Abstract  |  PDF  |  Full Text  |  How to cite

Corrections

Correction: Prognostic and diagnostic significance of lncRNAs expression in cervical cancer: a systematic review and metaanalysis

https://doi.org/10.18632/oncotarget.22570
100957-100957
Correction  |  PDF  |  How to cite


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