VOLUME 9 (2018)
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About The Cover
The cover for issue 4 of Oncotarget features Figure 1, "Niclosamide effectively and selectively inhibits viability of AML cells," from Chae, et al.
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Table of Contents
Editorial
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| What is treatment free remission in chronic myeloid leukemia |
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https://doi.org/10.18632/oncotarget.23398
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| 4279-4279 |
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| Targeting PR1 in myeloid leukemia |
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https://doi.org/10.18632/oncotarget.23403
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| 4280-4281 |
Priority Research Papers
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| Progesterone receptor isoforms agonists and antagonists differentially reprogram estrogen signaling |
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https://doi.org/10.18632/oncotarget.21378
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| 4282-4300 |
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| Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREBdependent signaling pathways |
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https://doi.org/10.18632/oncotarget.23794
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| 4301-4317 |
Research Papers: Immunology
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| Sodium fluoride causes hepatocellular Sphase arrest by activating ATMp53p21 and ATRChk1Cdc25A pathways in mice |
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https://doi.org/10.18632/oncotarget.23093
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| 4318-4337 |
Research Papers
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| Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma |
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https://doi.org/10.18632/oncotarget.22774
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| 4338-4353 |
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| Discovery and functional implications of a miR29b1/miR29a cluster polymorphism in acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.23150
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| 4354-4365 |
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| Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter |
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https://doi.org/10.18632/oncotarget.10525
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| 4366-4374 |
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| Clinical and molecular features of innate and acquired resistance to antiPD1/PDL1 therapy in lung cancer |
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https://doi.org/10.18632/oncotarget.23315
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| 4375-4384 |
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| Transfusionassociated adverse reactions TAARs and cytokine accumulations in the stored blood components: the impact of prestorage versus poststorage leukoreduction |
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https://doi.org/10.18632/oncotarget.23136
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| 4385-4394 |
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| Impact of DLK1DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer |
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https://doi.org/10.18632/oncotarget.10611
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| 4395-4410 |
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| LncRNA MALAT1 regulates smooth muscle cell phenotype switch via activation of autophagy |
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https://doi.org/10.18632/oncotarget.23230
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| 4411-4426 |
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| Comparative gene expression profiling of human metallothionein3 upregulation in neuroblastoma cells and its impact on susceptibility to cisplatin |
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https://doi.org/10.18632/oncotarget.23333
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| 4427-4439 |
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| RAS GTPases are modified by SUMOylation |
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https://doi.org/10.18632/oncotarget.23269
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| 4440-4450 |
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| Fibrosisrelated miRNAs as serum biomarkers for pancreatic ductal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.23377
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| 4451-4460 |
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| The inhibition of PLCγ1 protects chondrocytes against osteoarthritis implicating its binding to Akt |
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https://doi.org/10.18632/oncotarget.23286
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| 4461-4474 |
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| Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV4 |
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https://doi.org/10.18632/oncotarget.23381
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| 4475-4484 |
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| Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies |
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https://doi.org/10.18632/oncotarget.23321
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| 4485-4495 |
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| A dual mechanism of activation of the Sonic Hedgehog pathway in anaplastic thyroid cancer: crosstalk with RASBRAFMEK pathway and ligand secretion by tumor stroma |
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https://doi.org/10.18632/oncotarget.23388
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| 4496-4510 |
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| AMPK activation by Tanshinone IIA protects neuronal cells from oxygenglucose deprivation |
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https://doi.org/10.18632/oncotarget.23391
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| 4511-4521 |
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| Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome |
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https://doi.org/10.18632/oncotarget.23393
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| 4522-4536 |
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| APOBECmediated mutagenesis in urothelial carcinoma is associated with improved survival mutations in DNA damage response genes and immune response |
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https://doi.org/10.18632/oncotarget.23344
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| 4537-4548 |
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| Signature of survival: a 18FFDG PET based wholeliver radiomic analysis predicts survival after 90YTARE for hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.23423
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| 4549-4558 |
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| Adduction to arginine detoxifies aflatoxin B1 by eliminating genotoxicity and altering in vitro toxicokinetic profiles |
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https://doi.org/10.18632/oncotarget.23382
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| 4559-4570 |
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| Inhibition of autophagyattenuated calcium oxalate crystalinduced renal tubular epithelial cell injury in vivo and in vitro |
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https://doi.org/10.18632/oncotarget.23383
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| 4571-4582 |
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| Quantitative metabolomics for investigating the value of polyamines in the early diagnosis and therapy of colorectal cancer |
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https://doi.org/10.18632/oncotarget.22885
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| 4583-4592 |
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| αTocopherol succinate enhances pterostilbene antitumor activity in human breast cancer cells in vivo and in vitro |
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https://doi.org/10.18632/oncotarget.23390
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| 4593-4606 |
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| Prognostic factors for olfactory groove meningioma with nasal cavity extension |
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https://doi.org/10.18632/oncotarget.23461
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| 4607-4613 |
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| Computational methods reveal novel functionalities of PIWIinteracting RNAs in human papillomavirusinduced head and neck squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.23464
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| 4614-4624 |
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| Olinked Nacetylglucosamine transferase enhances secretory clusterin expression via liver X receptors and sterol response element binding protein regulation in cervical cancer |
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https://doi.org/10.18632/oncotarget.23588
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| 4625-4636 |
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| PDL1 confers resistance to EGFR mutationindependent tyrosine kinase inhibitors in nonsmall cell lung cancer via upregulation of YAP1 expression |
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https://doi.org/10.18632/oncotarget.23161
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| 4637-4646 |
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| Suppression of homologydependent DNA doublestrand break repair induces PARP inhibitor sensitivity in VHLdeficient human renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.23470
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| 4647-4660 |
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| Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathologicalmolecular analysis |
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https://doi.org/10.18632/oncotarget.23163
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| 4661-4674 |
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| Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma |
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https://doi.org/10.18632/oncotarget.22563
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| 4675-4697 |
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| Association of SNPs in the TIMP2 gene and large artery atherosclerotic stroke in southern Chinese Han population |
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https://doi.org/10.18632/oncotarget.23473
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| 4698-4706 |
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| Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer |
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https://doi.org/10.18632/oncotarget.23523
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| 4707-4721 |
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| Activation of MAPK signalling results in resistance to saracatinib AZD0530 in ovarian cancer |
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https://doi.org/10.18632/oncotarget.23524
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| 4722-4736 |
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| Personalized adoptive immunotherapy for patients with EBVassociated tumors and complications: Evaluation of novel naturally processed and presented EBVderived Tcell epitopes |
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https://doi.org/10.18632/oncotarget.23531
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| 4737-4757 |
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| Quantitative highthroughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing |
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https://doi.org/10.18632/oncotarget.23462
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| 4758-4772 |
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| Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyteerythroid progenitors and reduction of granulocytemacrophage progenitors |
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https://doi.org/10.18632/oncotarget.23463
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| 4773-4786 |
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| Induction of endoplasmic reticulum stress and mitochondrial dysfunction dependent apoptosis signaling pathway in human renal cancer cells by norcantharidin |
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https://doi.org/10.18632/oncotarget.23465
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| 4787-4797 |
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| Coexpression analysis revealed PTCH13’UTR promoted cell migration and invasion by activating miR1013p/SLC39A6 axis in nonsmall cell lung cancer: implicating the novel function of PTCH1 |
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https://doi.org/10.18632/oncotarget.23219
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| 4798-4813 |
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| A novel classifier based on three preoperative tumor markers predicting the cancerspecific survival of gastric cancer CEA CA199 and CA724 |
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https://doi.org/10.18632/oncotarget.23307
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| 4814-4822 |
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| miRNA regulation of Tip110 expression and selfrenewal and differentiation of human CD34+ hematopoietic cells |
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https://doi.org/10.18632/oncotarget.23572
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| 4823-4832 |
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| TNFα inhibits SATB2 expression and osteoblast differentiation through NFκB and MAPK pathways |
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https://doi.org/10.18632/oncotarget.23373
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| 4833-4850 |
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| Upregulation of LncRNA BCYRN1 promotes tumor progression and enhances EpCAM expression in gastric carcinoma |
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https://doi.org/10.18632/oncotarget.23585
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| 4851-4861 |
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| Morphologic predictors of pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer |
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https://doi.org/10.18632/oncotarget.23419
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| 4862-4874 |
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| Peptide inhibition of the SETD6 methyltransferase catalytic activity |
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https://doi.org/10.18632/oncotarget.23591
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| 4875-4885 |
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| MiR3615p suppresses chemoresistance of gastric cancer cells by targeting FOXM1 via the PI3K/Akt/mTOR pathway |
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https://doi.org/10.18632/oncotarget.23513
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| 4886-4896 |
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| Bloodbrain barrier disruption induced by diagnostic ultrasound combined with microbubbles in mice |
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https://doi.org/10.18632/oncotarget.23527
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| 4897-4914 |
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| Arsenic exposure assists ccm3 genetic polymorphism in elevating blood pressure |
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https://doi.org/10.18632/oncotarget.23518
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| 4915-4923 |
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| miR30a suppresses lung cancer progression by targeting SIRT1 |
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https://doi.org/10.18632/oncotarget.23529
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| 4924-4934 |
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| Heterotypic breast cancer model based on a silk fibroin scaffold to study the tumor microenvironment |
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https://doi.org/10.18632/oncotarget.23574
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| 4935-4950 |
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| Efficacy of granulocytemacrophage colonystimulating factor combined with metronomic paclitaxel in the treatment of Lewis lung carcinoma transplanted in mice |
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https://doi.org/10.18632/oncotarget.23530
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| 4951-4960 |
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| Assessment of a new genomic classification system in acute myeloid leukemia with a normal karyotype |
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https://doi.org/10.18632/oncotarget.23575
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| 4961-4968 |
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| Cistrimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells |
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https://doi.org/10.18632/oncotarget.23576
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| 4969-4984 |
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| The microtubuleassociated protein PRC1 is a potential therapeutic target for lung cancer |
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https://doi.org/10.18632/oncotarget.23577
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| 4985-4997 |
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| Osteopontin–integrin engagement induces HIF1α–TCF12mediated endothelialmesenchymal transition to exacerbate colorectal cancer |
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https://doi.org/10.18632/oncotarget.23578
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| 4998-5015 |
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| Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYCdriven cancer |
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https://doi.org/10.18632/oncotarget.23579
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| 5016-5031 |
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| Comparison of hepatic and serum lipid signatures in hepatocellular carcinoma patients leads to the discovery of diagnostic and prognostic biomarkers |
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https://doi.org/10.18632/oncotarget.23494
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| 5032-5043 |
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| Nonlinear mixed effects dose response modeling in high throughput drug screens: application to melanoma cell line analysis |
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https://doi.org/10.18632/oncotarget.23495
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| 5044-5057 |
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| Prognostic value of PD –L1 expression in patients with primary solid tumors |
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https://doi.org/10.18632/oncotarget.23580
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| 5058-5072 |
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| Aberrant frequency of TNFR2+ Treg and related cytokines in patients with CIN and cervical cancer |
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https://doi.org/10.18632/oncotarget.23581
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| 5073-5083 |
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| Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates prosurvival signaling |
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https://doi.org/10.18632/oncotarget.23598
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| 5084-5104 |
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| LncRNA gadd7 increased in varicocele patients suppresses cell proliferation and promotes cell apoptosis |
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https://doi.org/10.18632/oncotarget.23696
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| 5105-5110 |
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| Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to Xray irradiation |
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https://doi.org/10.18632/oncotarget.23700
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| 5111-5124 |
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| Pentraxin3 procalcitonin and lactate as prognostic markers in patients with sepsis and septic shock |
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https://doi.org/10.18632/oncotarget.23701
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| 5125-5136 |
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| Low FAT4 expression is associated with a poor prognosis in gastric cancer patients |
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https://doi.org/10.18632/oncotarget.23702
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| 5137-5154 |
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| MicroRNA340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L |
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https://doi.org/10.18632/oncotarget.23703
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| 5155-5168 |
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| Methyl donor Sadenosylmethionine SAM supplementation attenuates breast cancer growth invasion and metastasis in vivo; therapeutic and chemopreventive applications |
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https://doi.org/10.18632/oncotarget.23704
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| 5169-5183 |
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| Brucella induces unfolded protein response and inflammatory response via GntR in alveolar macrophages |
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https://doi.org/10.18632/oncotarget.23706
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| 5184-5196 |
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| Promiximabduocarmycin a new CD56 antibodydrug conjugates is highly efficacious in small cell lung cancer xenograft models |
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https://doi.org/10.18632/oncotarget.23708
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| 5197-5207 |
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| CRISPR knock out of programmed cell death protein 1 enhances antitumor activity of cytotoxic T lymphocytes |
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https://doi.org/10.18632/oncotarget.23730
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| 5208-5215 |
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| Characterization of CDK5 inhibitor 20223 aka CP668863 for colorectal cancer therapy |
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https://doi.org/10.18632/oncotarget.23749
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| 5216-5232 |
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| REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature |
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https://doi.org/10.18632/oncotarget.23750
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| 5233-5250 |
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| Carotid artery wall shear stress is independently correlated with renal function in the elderly |
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https://doi.org/10.18632/oncotarget.23825
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| 5251-5262 |
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| Prostateselective α antagonists increase fracture risk in prostate cancer patients with and without a history of androgen deprivation therapy: a nationwide populationbased study |
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https://doi.org/10.18632/oncotarget.23828
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| 5263-5273 |
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| Inhibition of the MEK/ERK pathway augments nabpaclitaxelbased chemotherapy effects in preclinical models of pancreatic cancer |
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https://doi.org/10.18632/oncotarget.23684
|
| 5274-5286 |
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| Identifying characteristic miRNAsgenes and risk pathways of multiple sclerosis based on bioinformatics analysis |
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https://doi.org/10.18632/oncotarget.23866
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| 5287-5300 |
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| New cGMP analogues restrain proliferation and migration of melanoma cells |
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https://doi.org/10.18632/oncotarget.23685
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| 5301-5320 |
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| Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway |
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https://doi.org/10.18632/oncotarget.23915
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| 5321-5336 |
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| Dual trigger of triptorelin and HCG optimizes clinical outcome for high ovarian responder in GnRHantagonist protocols |
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https://doi.org/10.18632/oncotarget.23916
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| 5337-5343 |
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| Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells |
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https://doi.org/10.18632/oncotarget.23747
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| 5344-5367 |
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| Dipyridamole decreases dialysis risk and improves survival in patients with predialysis advanced chronic kidney disease |
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https://doi.org/10.18632/oncotarget.19850
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| 5368-5377 |
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| Diagnostic value of WIF1 methylation for colorectal cancer: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23870
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| 5378-5386 |
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| Prevalence of celiac disease in patients with Down syndrome: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23624
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| 5387-5396 |
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| Diagnostic value of circulating microRNAs for liver cirrhosis: a metaanalysis |
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https://doi.org/10.18632/oncotarget.23332
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| 5397-5405 |
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| A metaanalysis of the lymphatic microvessel density and survival in gastric cancer with 1809 cases |
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https://doi.org/10.18632/oncotarget.23526
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| 5406-5415 |
Clinical Research Papers
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| Effect of metformin on kidney function in patients with type 2 diabetes mellitus and moderate chronic kidney disease |
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https://doi.org/10.18632/oncotarget.23387
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| 5416-5423 |
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| Experiment research of focused ultrasound combined with drug and microbubble for treatment of central nervous system leukemia |
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https://doi.org/10.18632/oncotarget.23521
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| 5424-5434 |
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| Effect of postoperative systemic therapy on pulmonary adenocarcinoma with unexpected pleural spread detected during thoracotomy or thoracoscopy |
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https://doi.org/10.18632/oncotarget.23686
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| 5435-5444 |
Reviews
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| MicroRNA expression and activity in Tcell acute lymphoblastic leukemia |
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https://doi.org/10.18632/oncotarget.23539
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| 5445-5458 |
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| Targeted drugs for systemic therapy of lung cancer with brain metastases |
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https://doi.org/10.18632/oncotarget.23616
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| 5459-5472 |
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| miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.16681
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| 5473-5479 |
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| Decorin is a pivotal effector in the extracellular matrix and tumour microenvironment |
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https://doi.org/10.18632/oncotarget.23869
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| 5480-5491 |
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| Exon 3 mutations of CTNNB1 drive tumorigenesis: a review |
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https://doi.org/10.18632/oncotarget.23695
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| 5492-5508 |
Case Reports
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| Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature |
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https://doi.org/10.18632/oncotarget.23768
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| 5509-5513 |
Corrections
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| Correction: Diagnostic performance enhancement of pancreatic cancer using proteomic multimarker panel |
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https://doi.org/10.18632/oncotarget.24175
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| 5514-5514 |
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