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- Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure
- COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms.
- The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology
- Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways
- A diagnostic autoantibody signature for primary cutaneous melanoma
- Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects
- The NF1 gene revisited – from bench to bedside
- p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression
- Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience
- The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair
- Inflammatory responses and inflammation-associated diseases in organs
- Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis
- Precision oncology in advanced cancer patients improves overall survival with lower weekly healthcare costs
- E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts
- Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?
- Enumeration and targeted analysis of KRAS , BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer
- Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers
- The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis
- A functional signal profiling test for identifying a subset of HER2-negative breast cancers with abnormally amplified HER2 signaling activity
- Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions
- Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma
- Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma
- ERβ inhibits cyclin dependent kinases 1 and 7 in triple negative breast cancer
- Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer
- Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line
- Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma
- Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis
- Plasma thymidine kinase-1 activity predicts outcome in patients with hormone receptor positive and HER2 negative metastatic breast cancer treated with endocrine therapy
- Prognostic significance of soluble mesothelin in malignant pleural mesothelioma: a meta-analysis
- Symmetry and symmetry breaking in cancer: a foundational approach to the cancer problem
- P62 plasmid can alleviate diet-induced obesity and metabolic dysfunctions
- C1orf64 is a novel androgen receptor target gene and coregulator that interacts with 14-3-3 protein in breast cancer
- Long-term supplementation of decaffeinated green tea extract does not modify body weight or abdominal obesity in a randomized trial of men at high risk for prostate cancer
- Prognostic significance of neutrophil-to-lymphocyte ratio in patients with malignant pleural mesothelioma: a meta-analysis
- Simultaneous silencing of TGF-β1 and COX-2 reduces human skin hypertrophic scar through activation of fibroblast apoptosis
- Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA
- Methylation of HPV and a tumor suppressor gene reveals anal cancer and precursor lesions
- Clinical strategies for acquired epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small-cell lung cancer patients
- Targeting folate receptor alpha for cancer treatment
- Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality
- Phase III study of cisplatin with pemtrexed or vinorelbine plus concurrent late course accelerated hyperfractionated radiotherapy in patients with unresectable stage III non-small cell lung cancer
- Protection from chemotherapy- and antibiotic-mediated dysbiosis of the gut microbiota by a probiotic with digestive enzymes supplement
- Oleuropein, unexpected benefits!
- Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1
- One-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy
- Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?
- Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)
- Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare
- Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas
- Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis
- Physical activity and telomere length: Impact of aging and potential mechanisms of action
- Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma
- Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16
- Stem cells in cancer therapy: opportunities and challenges
- Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
- Triple-negative breast cancer: is there a treatment on the horizon?
- Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy
- Induction of DISE in ovarian cancer cells in vivo
- An inverse association between tea consumption and colorectal cancer risk
- Nanoparticles and female reproductive system: how do nanoparticles affect oogenesis and embryonic development
- The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth
- Increased risk of cerebrovascular accident related to non-alcoholic fatty liver disease: a meta-analysis
- Quercetin induces cell apoptosis of myeloma and displays a synergistic effect with dexamethasone in vitro and in vivo xenograft models
- Cannabinoids as therapeutic agents in cancer: current status and future implications
- Prognostic significance of HER3 in patients with malignant solid tumors
- A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative
- Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice
- Melatonin for the prevention and treatment of cancer
- A global comparison of the cost of patented cancer drugs in relation to global differences in wealth
- Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization
- Use of genetically encoded, light-gated ion translocators to control tumorigenesis
- Metformin and berberine, two versatile drugs in treatment of common metabolic diseases
- LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair
- Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells
- Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells
- Graphene oxide selectively targets cancer stem cells, across multiple tumor types: Implications for non-toxic cancer treatment, via “differentiation-based nano-therapy”
- Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties
- Nanoformulations of curcumin; an emerging paradigm for improved remedial application
- Cancer prevention with rapamycin
- The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts
- Exclusive destruction of mitotic spindles in human cancer cells
- Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease
- The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells
- Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine
- Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging
- Breast tissue, oral and urinary microbiomes in breast cancer
- Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors
- Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer
- Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system
- The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations
- Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model
- Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial
- Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer
- Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells
- Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay
- Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay
- Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer
- Molecular hydrogen: a preventive and therapeutic medical gas for various diseases
- Copy number of latent viruses, oncogenicity, and the microcompetition model
- Health effects of a forest environment on natural killer cells in humans: an observational pilot study
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